The small GTPase MRAS is a broken switch by Gabriela Bernal Astrain, Regina Strakhova, Chang Hwa Jo, Emma Teszner, Ryan C. Killoran, Matthew J. Smith

“…Acquisition of NMR spectra from isotopically labeled MRAS in live cells validated the GTPase remains fully GDP-loaded, even a supposed activated mutant. …”
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Effect of physical activity on structural asymmetry of mouse hippocampus by T. A. Zapara, A. V. Romashchenko, A. L. Proskura, A. S. Ratushnyak

“…The existing immunohistochemical methods for labeling new neurons do not allow tracing the temporal dynamics of changes in the volume of brain structures in the same animal, induced by external impacts, such as voluntary exercise. …”
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Driver Takeover Performance Prediction Based on LSTM-BiLSTM-ATTENTION Model by Lijie Chen, Daofei Li, Tao Wang, Jun Chen, Quan Yuan

“…By building a takeover scenario and conducting experiments in the driving simulation experimental platform under the human–machine co-driving environment, the relevant state indicators in the 15 s per second before the takeover request is sent are extracted from three perspectives, namely, driver state, traffic environment, and personal attributes, as model inputs, and the level of takeover performance was labeled; the hybrid LSTM-BiLSTM-ATTENTION algorithm is used to construct a driver takeover performance prediction model and compare it with other five algorithms. …”
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Influence of Exposure to Benzo[a]pyrene on Mice Testicular Germ Cells during Spermatogenesis by Hueiwang Anna Jeng, Silvina M. Bocca

“…Apoptotic response of germ cells and mature spermatozoa were qualified using the terminal deoxynucleotidyl transferase mediated deoxy-UTP nick end labeling (TUNEL) assay. B[a]P exposure at ≤10 mg/kg/day for 30 days did not significantly alter concentrations of germ cells and mature spermatozoa and apoptotic response in germ cells and mature spermatozoa. …”
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Self-Supervised Chinese Ontology Learning from Online Encyclopedias by Fanghuai Hu, Zhiqing Shao, Tong Ruan

“…We explore the three largest online Chinese encyclopedias for ontology learning and describe how to transfer the structured knowledge in encyclopedias, including article titles, category labels, redirection pages, taxonomy systems, and InfoBox modules, into ontological form. …”
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Remimazolam Combined with Andrographolide Improve Postoperative Cognitive Dysfunction in Rats after Cardiopulmonary Bypass through the AMPK/SIRT1 Signaling Pathway by Chong Chen, Lixia Lan, Kai Xu

“…Apoptosis was evaluated using western blotting and the terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling (TUNEL) staining assay. …”
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Bupropion Mediated Effects on Depression, Attention Deficit Hyperactivity Disorder, and Smoking Cessation by Austin Clark, Brendan Tate, Bretton Urban, Ryan Schroeder, Sonja Gennuso, Shahab Ahmadzadeh, David McGregor, Brook Girma, Sahar Shekoohi, Alan D. Kaye

“…We evaluated the efficacy of major on and off-label uses of bupropion, focusing on the indications, benefits, and adverse effects. …”
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RMGANets: reinforcement learning-enhanced multi-relational attention graph-aware network for anti-money laundering detection by Qianyu Wang, Wei-Tek Tsai, Bowen Du

“…Additionally, the limited number of labels for illegal transactions results in severe class imbalance and other challenges. …”
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Allergic Contact Dermatitis Reaction to Permanent Tattoo Containing Paraphenylenediamine: A Case Report by Eliot Parascandolo, Samuel Puglisi, Miguel Marenco, Gregory Puglisi

“…We advocate for consistent ingredient labeling, regulation, and transparency within the tattoo ink industry.…”
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Coping with the Forced Swim Stressor: Towards Understanding an Adaptive Mechanism by E. R. de Kloet, M. L. Molendijk

“…A PubMed analysis revealed that in a rapidly increasing number of papers (currently more than 2,000) stress-related immobility in the FST is labeled as a depression-like phenotype. In this contribution we will examine the different phases of information processing during coping with the forced swim stressor. …”
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Supervised contrastive pre-training models for mammography screening by Zhenjie Cao, Zhuo Deng, Zhicheng Yang, Jie Ma, Lan Ma

“…Mammography screening is the most effective method for early detection and diagnosis of breast cancer. Due to the lack of labeled mammograms, building an AI system for mammography screening often relies heavily on human-designed data augmentation, which doesn’t always perform robustly when applied to clinical scenarios. …”
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Pesticide use in vegetable production in rural Uganda - A case study of Kabale District, South western Uganda by Hannington, Ngabirano, Grace, Birungi

“…Only 18% of the interviewed farmers could interpret instructions on pesticide container or bag labels correctly. All farmers (100%) had never attended any training on pesticide use. …”
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Traffic Flow Parameters Collection under Variable Illumination Based on Data Fusion by Shaojie Jin, Ying Gao, Shoucai Jing, Fei Hui, Xiangmo Zhao, Jianzhen Liu

“…We collected a new dataset to train the proposed method, which consists of 1000 natural daytime images and 1000 simulated nighttime images with a total of 23094 vehicles counted, where the simulated nighttime images are generated by a style translator named CycleGAN to reduce labeling workload. Another four datasets of 2400 images containing 20161 vehicles were collected to test the proposed method. …”
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Improving clinical care of patients in Nipah outbreaks: moving beyond ‘compassionate use’ by Md Zakiul Hassan, Amanda Rojek, Piero Olliaro, Peter Horby

“…Current care relies on supportive measures and the ‘compassionate use’ of unapproved drugs like ribavirin and remdesivir. Drugs used ‘off-label’ during outbreaks can become the ‘standard of care’ without robust evidence of their safety or efficacy, complicating the testing of new therapies and perpetuating uncertainty about their true effectiveness. …”
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A Novel Remote Sensing Recognition Using Modified GMM Segmentation and DenseNet by Muhammad Waqas Ahmed, Moneerah Alotaibi, Sultan Refa Alotaibi, Dina Abdulaziz Alhammadi, Asaad Algarni, Ahmad Jalal, Jeongho Cho

“…However, challenges such as limited labeled data, inherent data complexity, and high computational demands often hinder the performance of traditional methods. …”
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PHARAOH: A collaborative crowdsourcing platform for phenotyping and regional analysis of histology by Kevin Faust, Min Li Chen, Parsa Babaei Zadeh, Dimitrios G. Oreopoulos, Alberto J. Leon, Ameesha Paliwal, Evelyn Rose Kamski-Hennekam, Marly Mikhail, Xianpi Duan, Xianzhao Duan, Mugeng Liu, Narges Ahangari, Raul Cotau, Vincent Francis Castillo, Nikfar Nikzad, Richard J. Sugden, Patrick Murphy, Safiyh S. Aljohani, Philippe Echelard, Susan J. Done, Kiran Jakate, Zaid Saeed Kamil, Yazeed Alwelaie, Mohammed J. Alyousef, Noor Said Alsafwani, Assem Saleh Alrumeh, Rola M. Saleeb, Maxime Richer, Lidiane Vieira Marins, George M. Yousef, Phedias Diamandis

“…By providing cluster-level labels on only a handful of cases, we show how custom PHARAOH models can be developed efficiently and used to guide the quantification of cellular features that correlate with molecular, pathologic and patient outcome data. …”
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DiffRSS: A Diffusion-Guided Multi-Scale Features Remote Sensing Image Segmentation Method by Honghao Liu, Ruixia Yang, Yue Xu, Zhengchao Chen, Yuyang Zheng

“…This top-down generative approach learns the data distribution of sample labels and uses image features as guiding priors for generating segmentation masks. …”
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Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential by Jingyi Yuan, Zhenmin Li, Yongjiang Yu, Xiuge Wang, Yunyun Zhao

“…However, these treatments may often lead to adverse effects, and most medications prescribed for PCOS are used off-label and have not secured approval from the U.S. …”
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Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction by Xiaodan Jiang, Huibin Lv, Hang Song, Mingzhou Zhang, Yan Liu, Xiaodan Hu, Xuemin Li, Wei Wang

“…This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, day 45, and day 75. …”
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Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma by Žane Temova Rakuša, Robert Roškar, Anita Klančar Andrejc, Tina Trdan Lušin, Nataša Faganeli, Iztok Grabnar, Aleš Mrhar, Albin Kristl, Jurij Trontelj

“…The plasma samples containing rifampicin and isotopically labelled internal standard rifampicin D8, were cleaned up using a Captiva ND Lipids filtration plate. …”
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