Triptorelin in the Relief of Lower Urinary Tract Symptoms in Advanced Prostate Cancer Patients: The RESULT Study by Alexandre Peltier, Fouad Aoun, Vincent De Ruyter, Patrick Cabri, Roland Van Velthoven

“…This prospective, noninterventional, open-label, multicentre, Belgian study assessed the prevalence of moderate to severe lower urinary tract symptoms (LUTS) in patients with locally advanced or metastatic prostate cancer scheduled to receive triptorelin therapy and its effects on LUTS were evaluated focusing on symptom relief and changes in quality of life (QOL) related to urinary symptoms (November 2006 to May 2010). …”
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Trajectory inference from single-cell genomics data with a process time model. by Meichen Fang, Gennady Gorin, Lior Pachter

“…We also compare our parameter estimates of degradation rates to those derived from metabolic labeling datasets, thereby showcasing the biophysical utility of Chronocell. …”
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Interpretable and integrative deep learning for discovering brain-behaviour associations by Corentin Ambroise, Antoine Grigis, Josselin Houenou, Vincent Frouin

“…Moreover, approaches based solely on clinician labels often fail to capture the complexity and variability of these conditions. …”
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Illustrated type catalogue of marine Isopoda (Crustacea: Peracarida) from the Museu Nacional/UFRJ, Brazil by Cristiana S. Serejo, Agatha C. S. Fernandes

“…By photographing the specimens and digitizing the collection specimens´ labels, we expect to improve internal management and offer free access to the data, so as to preserve and promote the museum´s collections, which guard important and unique information on world biodiversity.…”
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Transition from Ambrisentan to Bosentan in Pulmonary Arterial Hypertension: A Single-Center Prospective Study by Su-Gang Gong, Lan Wang, Bigyan Pudasaini, Ping Yuan, Rong Jiang, Qin-Hua Zhao, Jing He, Rui Zhang, Wen-hui Wu, Jin-Ming Liu, Cai-cun Zhou

“…Methods: Twenty PAH patients were enrolled into the single-center, open-labelled prospective study. Echocardiogram, WHO functional class (WHO-FC), 6-minute walking distance (6MWD), right heart catheterization, and hemotology were collected. …”
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Stromal Derived Factor-1/CXCR4 Axis Involved in Bone Marrow Mesenchymal Stem Cells Recruitment to Injured Liver by Kuai Xiao Ling, Li Peng, Zhang Jian Feng, Cao Wei, Yuan Wei Yan, Shao Nan, Guan Cheng Qi, Wang Zhi Wei

“…The concentration of SDF-1 increased as modeling time extended, which was determined by ELISA method. The Dir-labeled BMSCs were injected into the liver of the rats through portal vein. …”
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Real-Time Multi-Task Deep Learning Model for Polyp Detection, Characterization, and Size Estimation by Phanukorn Sunthornwetchapong, Kasichon Hombubpha, Kasenee Tiankanon, Satimai Aniwan, Pasit Jakkrawankul, Natawut Nupairoj, Peerapon Vateekul, Rungsun Rerknimitr

“…For the various tasks, the models are trained using datasets with incomplete labels, leading to a comparison of different training strategies. …”
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Causality-driven feature selection and domain adaptation for enhancing chemical foundation models in downstream tasks by Eduardo Soares, Victor Yukio Shirasuna, Emilio Vital Brazil, Karen Fiorella Aquino Gutierrez, Renato Cerqueira, Dmitry Zubarev, Kristin Schmidt, Daniel P Sanders

“…This methodology reduces reliance on labeled data, facilitating data acquisition and broadening the scope of chemical language representation. …”
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Supervised and Self-Supervised Learning for Assembly Line Action Recognition by Christopher Indris, Fady Ibrahim, Hatem Ibrahem, Götz Bramesfeld, Jie Huo, Hafiz Mughees Ahmad, Syed Khizer Hayat, Guanghui Wang

“…The comparative study was extended to self-supervised learning via a modified SPOT model, which achieved a mAP@IoU=0.1:0.7 of 65% with just 10% of the data labeled using extractor architectures from the fully-supervised portion. …”
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What Parents Think about Giving Nonnutritive Sweeteners to Their Children: A Pilot Study by Allison C. Sylvetsky, Mitchell Greenberg, Xiongce Zhao, Kristina I. Rother

“…Our findings also suggest that food labeling should be revised in order for consumers to more easily identify NNS in foods and beverages.…”
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Benefit from the Chin-Down Maneuver in the Swallowing Performance and Self-Perception of Parkinson’s Disease Patients by Annelise Ayres, Geraldo Pereira Jotz, Carlos R. M. Rieder, Maira Rozenfeld Olchik

“…Materials and Method. We performed an open-label trial, with three groups compounds by PD individuals: the experimental group, control group, and orientation group. …”
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Quantifying glucose uptake at the single cell level with confocal microscopy reveals significant variability within and across individuals by Joel D. Paprocki, Patrick J. Macdonald, Yongjin Xu, Alan Cheng, Timothy C. Dunn, Sergey Y. Tetin

“…For the first time, we demonstrate that intracellular/extracellular tracer percentages can be measured at the single cell level using the fluorescently labeled glucose analog, 2-NBDG. A small donor panel study indicates that the characteristic intracellular 2-NBDG percentages can statistically differ based on race (i.e., Caucasian/Hispanic vs Black). …”
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HER2-related biomarkers predict clinical outcomes with trastuzumab deruxtecan treatment in patients with HER2-expressing metastatic colorectal cancer: biomarker analyses of DESTINY... by Salvatore Siena, Kanwal Raghav, Toshiki Masuishi, Kensei Yamaguchi, Tomohiro Nishina, Elena Elez, Javier Rodriguez, Ian Chau, Maria Di Bartolomeo, Hisato Kawakami, Fumitaka Suto, Makito Koga, Koichiro Inaki, Yusuke Kuwahara, Issey Takehara, Daniel Barrios, Kojiro Kobayashi, Axel Grothey, Takayuki Yoshino

“…Abstract DESTINY-CRC01 (NCT03384940) was a multicentre, open-label, phase 2 study that investigated the safety and efficacy of trastuzumab deruxtecan (T-DXd) in patients with human epidermal growth factor receptor 2 (HER2)-expressing metastatic colorectal cancer (CRC). …”
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One Size Does Not Fit All: Face Emotion Processing Impairments in Semantic Dementia, Behavioural-Variant Frontotemporal Dementia and Alzheimer’s Disease Are Mediated by Distinct Co... by Laurie A. Miller, Sharpley Hsieh, Suncica Lah, Sharon Savage, John R. Hodges, Olivier Piguet

“…These analyses revealed that language impairments explained the original poor scores obtained by the SD patients on the Ekman 60 and Emotion Selection tasks, which involve verbal labels. Perceptual deficits contributed to Emotion Matching performance in the bvFTD and AD patients. …”
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Simple Spectrophotometric Method for Determination of Paroxetine in Tablets Using 1,2-Naphthoquinone-4-Sulphonate as a Chromogenic Reagent by Ibrahim A. Darwish, Heba H. Abdine, Sawsan M. Amer, Lama I. Al-Rayes

“…The proposed method was successfully applied to the determination of PRX in its pharmaceutical tablets with good accuracy and precisions; the label claim percentage was 97.17±1.06 %. The results obtained by the proposed method were comparable with those obtained by the official method.…”
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Elevated Transforming Growth Factor-β2 in the Aqueous Humor: A Possible Explanation for High Rate of Capsular Contraction Syndrome in High Myopia by Keke Zhang, Xiangjia Zhu, Minjie Chen, Xinghuai Sun, Jin Yang, Peng Zhou, Yi Lu

“…Histopathological analysis revealed proliferation of fibroblast-like lens epithelial cells on the shrunken anterior capsule, labeled with TGF-β2 antibodies. ELISA and Western blot showed higher levels of TGF-β2 in aqueous humor of patients with capsular contraction syndrome and high myopia. …”
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Separating and Characterizing Functional Nitrogen Degraders via Magnetic Nanoparticle-Mediated Isolation by Yujiao Sun, Meng Yin, Danyang Zheng, Lei Wang, Xiaohui Zhao, Jie Li

“…Magnetic nanoparticle-mediated isolation (MMI) is a new method for isolating active functional microbes from complex microorganisms without substrate labeling. In this study, the composition and properties of magnetic nanoparticles (MNPs) were characterized by a number of techniques, indicating that MNPs have characteristics such as microinterfaces and can be efficiently fixed on the surface of microbial cells. …”
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Derivation and Identification of Motor Neurons from Human Urine-Derived Induced Pluripotent Stem Cells by Huan Yi, Bingbing Xie, Ben Liu, Xuan Wang, Li Xu, Jia Liu, Min Li, Xiufeng Zhong, Fuhua Peng

“…The comparison of the ratios of positive labeling for MN markers between urine-iPSCs and B-iPSCs demonstrated that the differentiation potentials of these cells were not significantly different. …”
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APDL: an adaptive step size method for white-box adversarial attacks by Jiale Hu, Xiang Li, Changzheng Liu, Ronghua Zhang, Junwei Tang, Yi Sun, Yuedong Wang

“…This approach mitigates the edge effects associated with gradient attacks by adjusting the hardness and softness of labels. Experiments conducted on ImageNet-compatible datasets demonstrate that APDL is significantly faster than the commonly used nonadaptive methods, whereas the TDLF method exhibits strong transferability.…”
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Dyspepsia: When and How to Test for Helicobacter pylori Infection by Maria Pina Dore, Giovanni Mario Pes, Gabrio Bassotti, Paolo Usai-Satta

“…For patients without alarm symptoms, noninvasive testing for H. pylori, with either carbon-13-labeled urea breath testing or stool antigen testing, is recommended as a first-line strategy. …”
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