Semi-Supervised Change Detection with Data Augmentation and Adaptive Thresholding for High-Resolution Remote Sensing Images by Wuxia Zhang, Xinlong Shu, Siyuan Wu, Songtao Ding

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Promoting Shared Metacognition in Online Learning: The Practices of Distributed Teaching Presence and the Relationships to Cognitive Presence by Ye Chen, Lixuan Chen

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Anti-LAG-3 antibody LBL-007 plus anti-PD-1 antibody toripalimab in advanced nasopharyngeal carcinoma and other solid tumors: an open-label, multicenter, phase Ib/II trial by Gang Chen, Dong-Chen Sun, Yi Ba, Ya-Xiong Zhang, Ting Zhou, Yuan-Yuan Zhao, Hong-Yun Zhao, Wen-Feng Fang, Yan Huang, Zhen Wang, Chao Deng, De-Sheng Hu, Wei Wang, Jin-Guan Lin, Gui-Ling Li, Su-Xia Luo, Zhi-Chao Fu, Hai-Sheng Zhu, Hui-Li Wang, Sheng-Li Cai, Xiao-Qiang Kang, Li Zhang, Yun-Peng Yang

“…Abstract Purpose Open-label phase Ib/II study to investigate the safety and efficacy of LBL-007, an anti-LAG-3 antibody, plus toripalimab, an anti-PD-1 antibody, in patients with previously treated advanced nasopharyngeal carcinoma (NPC) and other solid tumors. …”
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Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumors by Matthew Burge, David Goldstein, Andrew Haydon, Nick Pavlakis, Charlotte Lemech, Edward Hammond, Darryn Bampton, Keith Dredge, Michael P Brown, Andrew Clouston, Nigel J Waterhouse, Amanda C Stanley, Lucie Leveque-El Mouttie, Grace M Chojnowski

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AOZORA: long-term safety and joint health in paediatric persons with haemophilia A without factor VIII inhibitors receiving emicizumab – protocol for a multicentre, open-label, phase IV clinical study by Seitaro Yoshida, Masashi Taki, Hideyuki Takedani, Midori Shima, Keiji Nogami, Azusa Nagao, Haruko Yamaguchi-Suita, Yui Kyogoku, Akira Ishiguro, Kaoru Kitsukawa

“…The AOZORA study will evaluate the long-term safety and joint health of paediatric PwHA without factor (F)VIII inhibitors taking emicizumab; here, we report the details of the study protocol and baseline data.Methods and analysis AOZORA is a multicentre, open-label, phase IV clinical study in Japan that aims to enrol approximately 30 PwHA aged <12 years without FVIII inhibitors. …”
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Comparative proteomic analysis reveals the effects of different fatty acid forms on high-fat diet mice by Jiaping Pan, Huan Wang, Ye Li, Chenyang Lu

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Part of Speech Tagging: Shallow or Deep Learning? by Robert Östling

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Advancements in nanosensors for cancer detection by Dinesh Bhatia, Tania Acharjee, Monika Bhatia

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Incorporation of anthocyanin into zein nanofibrous films by electrospinning: Structural characterization, functional properties, and ammonia color-responsiveness by Jun Wang, Wenpeng Zhao, Dongli Qin, Hongyan Shan, Xiaoman Zhu, Lilan Chen, Ying Liu, Songnan Li

Subjects: “…Freshness-indicating label…”
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MaDis-Stereo: Enhanced Stereo Matching via Distilled Masked Image Modeling by Jihye Ahn, Hyesong Choi, Soomin Kim, Dongbo Min

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Multidimensional evaluation of nutritional security policies in the Republic of Moldova: gaps, progress, and alignment with international standards by Rodica Siminiuc, Dinu Țurcanu, Sergiu Siminiuc

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Extracting Regular Building Footprints Using Projection Histogram Method from UAV-Based 3D Models by Yaoyao Ren, Xing Li, Fangyuqing Jin, Chunmei Li, Wei Liu, Erzhu Li, Lianpeng Zhang

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Implementing sustainability frameworks at a product-level – Exploring the usability by Paule Bhérer-Breton, Anna Woodhouse, Bente Aspeholen Åby, Hilke Bos-Brouwers, Melanie Kok, Hanne Fjerdingby Olsen

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Changes in the nutrient composition of top-selling packaged foods and beverages in Colombia between 2016 to 2021 by Luis Carlos Forero, Luis F. Gómez, Mercedes Mora-Plazas, María Parra-Murillo, María Parra-Murillo, Sara Toquica, Lindsey Smith Taillie

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Prevention of Acute Radiation-Induced Skin Reaction with NPE® Camellia Sinensis Nonfermentatum Extract in Female Breast Cancer Patients Undergoing Postoperative Radiotherapy: A Single Centre, Prospective, Open-Label Pilot Study by Gabriela Näf, Urs E. Gasser, Hans E. Holzgang, Sandra Schafroth, Christoph Oehler, Daniel R. Zwahlen

“…Twenty patients were enrolled in this single centre, prospective, open-label pilot study. The outcomes of 20 prospective data sets were compared with 100 retrospectively collected matched data sets derived from hospital records. …”
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Combined use of respiratory multiplex PCR and procalcitonin to reduce antibiotic exposure in sickle-cell adult patients with acute chest syndrome (The ANTIBIO-STA study): a randomised, controlled, open-label trialResearch in context by Alexandre Sabaté-Elabbadi, Armand Mekontso-Dessap, François Lionnet, Aline Santin, Charlotte Verdet, Paul-Louis Woerther, Julien Lopinto, Matthieu Turpin, Alexandra Rousseau, Romane Lacoste-Badie, Keyvan Razazi, Guillaume Voiriot, Muriel Fartoukh

“…Methods: We conducted a randomised, controlled, parallel group, open-label study in two French hospitals. Consecutive adult patients with ACS were randomly assigned to the conventional or interventional strategy, where antibiotic therapy was targeted on the results of mPCR performed on lower respiratory tract secretions (LRTS) samples, and antibiotic discontinuation based on PCT values and kinetics at Day 1 (D1), D3 and D7. …”
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Rationale and design of the multicenter, national, randomized, open labeled phase III trial: allogeneic stem cell transplantation as a potential curative treatment for patients with relapsed or progressed multiple myeloma (AlloRelapseMM Study) by Annemarie Glöckner, Stefan Schönland, Hermann Einsele, Nicolaus Kröger

“…Methods This clinical trial is a national, multicenter, randomized, open labeled phase III study conducted in 30 hospitals spread all over Germany. …”
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Prevalence of High Fat Sugar Salt Products, Labeling Characteristics, and Categories of Foods Sold within In-Store Restricted Areas: A Survey in 3 UK Supermarkets after the 2022 Implementation of the Food (Promotion and Placement) Regulations by Ella Hurst, Sally G Moore, Lewis W Wallis

Subjects: “…front-of-pack nutrition labeling…”
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Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-label, phase II, randomised controlled trial by Ying Zhu, Jianwei Zhou, Zhigang Zhang, Jiaojiao Zhang, Jing Fei, Xiaoqing Zhu

“…The NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr(NAIVE) study aims to assess the clinical efficacy and safety of NACT in combination with tislelizumab (a monoclonal antibody for programmed cell death protein 1) for advanced EOC.Methods and analysis The NAIVE study is an investigator-initiated, prospective, single-centre, open-label, randomised controlled trial for advanced EOC with the International Federation of Gynaecology and Obstetrics (FIGO) stage IIIc with a Suidan CT score of 3 or greater or a Fagotti laparoscopic score of 8 or greater; or FIGO stage IV. …”
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The near-optimal adjustment of carbon and nitrogen allocations into different organs in early-season rice cultivars with drastically different yield components under nitrogen appli... by Wen Ning, Wen Ning, Lin Su, Lin Su, Dandan Shi, Dandan Shi, Meina Ji, Meina Ji, Xiang Ouyang, Qingfeng Song, Caihong Shao, Xin-Guang Zhu, Shuoqi Chang, Shuoqi Chang

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