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  1. 2301

    Activation of Delta-Opioid Receptor Protects ARPE19 Cells against Oxygen-Glucose Deprivation/Reoxygenation-Induced Necroptosis and Apoptosis by Inhibiting the Release of TNF-α by Runjie Guo, Ping Chen, Tiantian Fu, Ren Zhang, Yuan Zhu, Nange Jin, Hong Xu, Yong Xia, Xuesong Tian

    Published 2022-01-01
    “…Calcein acetoxymethylester/propidium iodide (Calcein-AM/PI) and Terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) staining were used to detect necroptotic and apoptotic ARPE19 cells, respectively. …”
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  2. 2302

    Which PSMA PET/CT interpretation criteria most effectively diagnose prostate cancer? a retrospective cohort study by Le Ma, Yaxin Hao, Luoping Zhai, Wanchun Zhang, Xiaoming Cao, Kaiyuan Jia

    Published 2025-01-01
    “…Our study endeavors to pinpoint the most optimal criteria to enhance the precision of PCa diagnosis, encompassing clinically significant PCa (csPCa), by evaluating the consistency and diagnostic accuracy of these three criteria using two [18F]-labeled PSMA tracers. Method This retrospective analysis spans a five-year period, focusing on patients with clinically suspected or newly diagnosed, treatment-naïve PCa who underwent 18F-PSMA PET/CT. …”
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  3. 2303

    Study of a Deep Learning Reconstruction Algorithm for Displaying Small- and Medium-sized Blood Vessels in Upper Abdominal Energy Spectrum CT by Qin WANG, Weijie YAN, Yuan YUAN, Hehan TANG, Liping DENG

    Published 2025-01-01
    “…Simultaneously, 40 keV and 70 keV single-energy images were extracted using energy spectrum post-processing software, and four groups of images were generated, which were labeled as 40 keV-AV, 40 keV-DL-M, 40 keV-DL-H, and 70 keV-AV, respectively. …”
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  4. 2304

    Animal experiments and network pharmacology to explore the anti-inflammatory mechanism of dapagliflozin in the treatment of polycystic ovary syndrome by Yong Liu, He Bai, Huilin Guan, Chunhua Wang, Xueqing Song, Zihao Yong, Xiaomeng Guo, Luxin Li, Zhen Zhang

    Published 2025-12-01
    “…Pathological changes in the ovaries were examined by H&E staining, changes in ovarian tissue cell apoptosis were identified using TdT-mediated dUTP Nick-End Labeling (TUNEL) staining, and changes in inflammation-related factors were detected using immunohistochemistry and Western blotting analysis. …”
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  5. 2305

    Risk of diabetic ketoacidosis caused by sodium glucose cotransporter-2 inhibitors in patients with type 1 diabetes: a systematic review and network meta-analysis of randomized cont... by Ying Liu, Shiwen Yang, Aidou Jiang, Dan Zou, Zhaoyang Chen, Na Su, Na Su

    Published 2025-01-01
    “…However, SGLT2 inhibitors for treating T1DM are off label in China, and adverse reactions should be closely monitored during administration.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/#loginpage, identifier CRD42023416227.…”
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  6. 2306

    Association among high blood pressure health literacy, social support and health-related quality of life among a community population with hypertension: a community-based cross-sec... by Ting Chen, Wei Gan, Li Song, Yujie Wang, Huan Qi, Qinghua Zhang, Jinyu Yin

    Published 2022-06-01
    “…In multiple linear regression models, HRQoL was significantly associated with ‘Print HL’ and ‘Medication Label’ of HBP-HL (p<0.05) and all three dimensions of SS (p<0.05). …”
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  7. 2307

    Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial by Jiawei Shang, Ziming Yuan, Zuoyan Zhang, Quanhong Zhou, Yan Zou, Wei Wang

    Published 2025-02-01
    “…MethodsThis was an exploratory, prospective, open-label, parallel, single-center, randomized controlled trial. …”
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  8. 2308

    Effect of Staggered vs. Simultaneous Co-Administration of Bempedoic Acid on Pharmacokinetics of Pravastatin: Randomized, Cross-Over Clinical Trial in Healthy Volunteers by Felicitas Stoll, Salvatore Amato, Max Sauter, Jürgen Burhenne, Johanna Weiss, Walter E. Haefeli, Antje Blank

    Published 2025-01-01
    “…<b>Methods</b>: This was a single-centre, open-label, randomized, two-arm, cross-over, phase I drug interaction trial in healthy volunteers (EudraCT-No: 2022-001096-13). …”
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  9. 2309

    An exploratory study on the differential diagnostic indicators between adult systemic EBV-positive T-cell lymphoproliferative disorders and angioimmunoblastic T-cell lymphoma with... by Xiaodan Zheng, Yuanyuan Zheng, Yanlin Zhang, Jianlan Xie, Xiaojing Teng, Kuo Bi, Lan Sun, Xiaowen Huang, Mulan Jin, Xiaoge Zhou

    Published 2025-01-01
    “…Differences in immunophenotype, type of EBV-infected cells, clonality and gene mutations between the two groups of cases were compared by immunohistochemical staining, double-label staining, TCR gene rearrangement and next-generation sequencing analysis. …”
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  10. 2310

    Penggunaan Metode Naïve Bayes Classifier pada Analisis Sentimen Penilaian Masyarakat Terhadap Pelayanan Rumah Sakit di Malang by Tsania Dzulkarnain, Dian Eka Ratnawati, Bayu Rahayudi

    Published 2024-10-01
    “…After processing the data through text preprocessing and TF-IDF word weighting, data labeling, applying the Naive Bayes Classifier algorithm, and extracting negative sentiments to determine the Root Cause in negative hospital sentiments. …”
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  11. 2311

    Fetal Spinal Cord Tissue in Mini-Guidance Channels Promotes Longitudinal Axonal Growth after Grafting into Hemisected Adult Rat Spinal Cords by Norman I. Bamber, Huaying Li, Patrick Aebischer, Xiao Ming Xu

    Published 1999-01-01
    “…Immunofluorescence results indicated that numerous neurofilament-positive axons were present within the FSC tissue cable. Double-labeling of a subpopulation of these axons with calcitonin generelated peptide indicated their peripheral nervous system (PNS) origin. …”
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  12. 2312

    Cyberinfrastructure for machine learning applications in agriculture: experiences, analysis, and vision by Lucas Waltz, Sushma Katari, Chaeun Hong, Adit Anup, Julian Colbert, Anirudh Potlapally, Taylor Dill, Canaan Porter, John Engle, John Engle, Christopher Stewart, Hari Subramoni, Scott Shearer, Raghu Machiraju, Osler Ortez, Laura Lindsey, Arnab Nandi, Sami Khanal

    Published 2025-01-01
    “…While many agricultural use cases appear feasible with current compute resources and ML algorithms, the lack of reusable hardware and software components, referred to as cyberinfrastructure (CI), for collecting, transmitting, cleaning, labeling, and training datasets is a major hindrance toward developing solutions to address agricultural use cases. …”
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  13. 2313
  14. 2314

    Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells by Liping Mai, Guodong He, Jing Chen, Jiening Zhu, Shaoxian Chen, Xinghua Hou, Hui Yang, Mengzhen Zhang, Yueheng Wu, Qiuxiong Lin, Min Yang, Xiaohong Li

    Published 2021-01-01
    “…Tandem mass tag (TMT) labeling was combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for differential proteomic analysis of hypoxia in hBMSCs. …”
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  15. 2315

    Therapeutic Effect of Human Umbilical Cord Mesenchymal Stem Cells at Various Passages on Acute Liver Failure in Rats by Yongting Zhang, Yuwen Li, Wenting Li, Jie Cai, Ming Yue, Longfeng Jiang, Ruirui Xu, Lili Zhang, Jun Li, Chuanlong Zhu

    Published 2018-01-01
    “…Compared to P10 hUC-MSCs in vivo, P5 hUC-MSCs significantly enhanced the regeneration and inhibited the apoptosis of hepatocytes. CM-Dil-labeled hUC-MSCs were found to engraft within the recipient liver, whereas the homing of cells to the recipient liver in the P10 hUC-MSCs group was less effective compared to the P5 hUC-MSCs group. …”
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  16. 2316
  17. 2317
  18. 2318

    The Protocol for the Multi-Ethnic, multi-centre raNdomised controlled trial of a low-energy Diet for improving functional status in heart failure with Preserved ejection fraction (... by Noelle Robertson, Melanie J Davies, Thomas Yates, Gerry P McCann, Gaurav Singh Gulsin, Emer M Brady, Joanne V Wormleighton, Eylem Levelt, Oliver Rider, Jiliu Pan, Christopher Miller, Iain Squire, Mehak Asad, Fardad Soltani, Michelle Hadjiconstantinou, Rachel L Brown, Joanna M Bilak

    Published 2025-01-01
    “…This pragmatic randomised trial aims to evaluate the efficacy of MRP-directed weight loss on exercise intolerance, symptoms, quality of life and cardiovascular remodelling in a multiethnic cohort with obesity and HFpEF.Methods and analysis Prospective multicentre, open-label, blinded endpoint randomised controlled trial comparing low-energy MRP with guideline-driven care plus health coaching. …”
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  19. 2319
  20. 2320

    Comparing Deep Learning models for mapping rice cultivation area in Bhutan using high-resolution satellite imagery by Biplov Bhandari, Timothy Mayer

    Published 2025-01-01
    “…Further this study successfully demonstrated the usage of regional land cover products such as SERVIR’s Regional Land Cover Monitoring System (RLCMS) as a weak label approach to capture different strata addressing the class imbalance problem and improving the sampling design for Deep Learning application. …”
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