Distribution and clinicopathological characteristics of G-CSF expression in tumor cells and stromal cells in upper tract urothelial carcinoma by Go Kobayashi, Yohei Sekino, Hikaru Nakahara, Kohei Kobatake, Keisuke Goto, Tetsutaro Hayashi, Kazuhiro Sentani, Nobuyuki Hinata

“…We further showed that G-CSF expression was associated with a high Ki-67 labeling index and with PD-L1, HER2, and p53 expression in UTUC. …”
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UEF-HOCUrdu: Unified Embeddings Ensemble Framework for Hate and Offensive Text Classification in Urdu by Kifayat Ullah, Muhammad Aslam, Muhammad Usman Ghani Khan, Faten S. Alamri, Amjad Rehman Khan

“…The ensemble model performed the best and achieved macro F1 score of 0.94, complemented by comprehensive labeled dataset focusing on hate and offensive speech in Urdu. …”
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Study protocol of the METAPANC trial - intensified treatment in patients with local operable but oligometastatic pancreatic cancer - multimodal surgical treatment versus chemothera... by Michael Ghadimi, Uwe Pelzer, Marc G. Besselink, Jens Siveke, Ralph Telgmann, Rickmer Braren, Hanneke Wilmink, Marie Crede, Alexander Koenig, Ute Koenig, Sven Thorsten Liffers, Kai Antweiler, Bas Uijterwijk, Hanna Seppanen, Arno Nordin, Pauli Puolakkainen, Olav F. Dajani, Knut Jørgen Labori, Mia Johansson, Svein Olav Bratlie, Tim Friede, Peter Jo

“…Discussion METAPANC is the first international, randomized, controlled, open-label, multicentre, phase III clinical trial for curative intended surgical therapy of oligometastatic pancreatic cancer in Europe and America. …”
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Green Analytical Method for Simultaneous Determination of Glucosamine and Calcium in Dietary Supplements by Capillary Electrophoresis with Capacitively Coupled Contactless Conducti... by Yen Nhi Do, Thi Lan Phuong Kieu, Thi Huyen My Dang, Quang Huy Nguyen, Thu Hien Dang, Cao Son Tran, Anh Phuong Vu, Thi Trang Do, Thi Ngan Nguyen, Son Luong Dinh, Thi Minh Thu Nguyen, Thi Ngoc Mai Pham, Anh Quoc Hoang, Bach Pham, Thi Anh Huong Nguyen

“…The measured concentrations were generally in line with the values of label claims and with cross-checking data from reference methods (HPLC and ICP-OES).…”
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Tetracyclines in Rheumatoid Arthritis: Dual Anti-Inflammatory and Immunomodulatory Roles, Effectiveness, and Safety Insights by Mislav Radić, Andrej Belančić, Hana Đogaš, Marijana Vučković, Andrea Gelemanović, Andrea Faour, Ivan Vlak, Josipa Radić

“…Current guidelines for RA management do not explicitly recommend tetracyclines due to these limitations, although off-label use may be considered in specific cases. The use of tetracycline for RA is restricted by drug interactions causing bacterial resistance alongside unpredictable patient responses, hence the necessity for prudence in its prescription within a clinical setting. …”
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Immunohistochemical Profile of p62/SQSTM1/Sequestosome-1 in Human Low- and High-Grade Intracranial Meningiomas by Antonio Ieni, Cristina Pizzimenti, Vincenzo Fiorentino, Mariausilia Franchina, Antonino Germanò, Giovanni Raffa, Maurizio Martini, Guido Fadda, Giovanni Tuccari

“…However, intranuclear vacuoles have been ultrastructurally observed in meningiomas, and they were labelled by p62 antibodies. Therefore, in the present study, we have investigated p62 immunohistochemical pattern in a cohort of 133 cases representative of low- and high-grade meningiomas, to verify if p62 expression may be related to clinicopathological data, thus achieving a potential prognostic role. …”
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KE-RSIC: Remote Sensing Image Captioning Based on Knowledge Embedding by Kangda Cheng, Erik Cambria, Jinlong Liu, Yushi Chen, Zhilu Wu

“…We retrieve reports with similar label distributions to the input and then extract entities and relationships from the retrieved reports using a relation extractor. …”
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Targeting the Vasculature of Colorectal Carcinoma with a Fused Protein of (RGD)3-tTF by Zheng-jie Huang, Yilin Zhao, Wei-yuan Luo, Jun You, Shui-wen Li, Wen-cheng Yi, Sheng-yu Wang, Jiang-hua Yan, Qi Luo

“…The bioactivities of (RGD)3-tTF including coagulation activity, FX activation, and binding with integrin αvβ3 were performed. The fluorescent labeled (RGD)3-tTF was intravenously injected into tumor-bearing mice and traced in vivo. …”
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Exploring the exoproteome of the parasitic nematode Anisakis simplex (s. s.) and its impact on the human host – an in vitro cross-talk proteomic approach by Robert Stryiński, Robert Stryiński, Ewa Fiedorowicz, Jesús Mateos, Aneta Andronowska, Elżbieta Łopieńska-Biernat, Mónica Carrera

“…To achieve this goal, the shotgun proteomics method based on isobaric mass labeling (via tandem mass tags; TMT) was used with a combination of nano high-performance liquid chromatography (nLC) coupled with an LTQ-Orbitrap Elite mass spectrometer. …”
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Combining a Standardized Growth Class Assessment, UAV Sensor Data, GIS Processing, and Machine Learning Classification to Derive a Correlation with the Vigour and Canopy Volume of... by Ronald P. Dillner, Maria A. Wimmer, Matthias Porten, Thomas Udelhoven, Rebecca Retzlaff

“…To address these problems, based on a standardized growth class assessment, labeled ground truth data of precisely located grapevines were predicted with specifically selected Machine Learning (ML) classifiers (Random Forest Classifier (RFC), Support Vector Machines (SVM)), utilizing multispectral UAV (Unmanned Aerial Vehicle) sensor data. …”
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A Hybrid Efficient U-Net Framework for Detection of Anterior Belly of the Digastric Muscle on Ultrasonography by Sule Erdem, Suheda Erdem, Muammer Turkoglu, Abdulkadir Sengur, Nebras M. Sobahi

“…The visual results showed that the segmentation masks of the MultiResUNet-Fusion models provided predictions close to the real labels, and all models generally localized the region of interest accurately. …”
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Improved ChIP Sequencing for H3K27ac Profiling and Super-Enhancer Analysis Assisted by Fluorescence-Activated Sorting of Formalin-Fixed Paraffin-Embedded Tissues by Nenggang Jiang, Zhihao Wen, Huan Tao, Hongyan Liao

“…Essential steps included single cell preparation, heat treatment enhancing antigen retrieval and labeling, cell sorting, chromatin shearing, ChIP and NGS. …”
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Dual‐fluorescence imaging and automated trophallaxis detection for studying multi‐nutrient regulation in superorganisms by Lior Baltiansky, Einav Sarafian‐Tamam, Efrat Greenwald, Ofer Feinerman

“…Our dual‐fluorescence imaging set‐up is designed to track two food sources, each labelled with a different fluorophore, as they are disseminated throughout a freely behaving colony of individually tagged ants. …”
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Study on Management of Blood Transfusion Therapy in Patients with Hereditary Spherocytosis by Shiyue Ma, Lingjian Tang, Chaoli Wu, Hui Tang, Xue Pu, Jinhong Niu

“…The fluorescence of EMA-labeled red blood cell (RBC) was decreased. DNA sequencing showed that His54Pro, Leu1858Val, and 6531-12C>T compound heterozygous mutations were present in the SPTA1 gene of patient I-1, Arg344Gln and c.609+86G>A heterozygous mutations were present in the SLC4A1 gene of patient II-1, and Leu2032Pro homozygous mutation was present in the SPTB gene of patient III-1. …”
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A New Approach to Determine the Total Airborne N Input into the Soil/Plant System Using 15N Isotope Dilution (ITNI): Results for Agricultural Areas in Central Germany by Rolf W.B. Russow, Frank Bahme, Heinz-Ulrich Neue

“…A soil/plant system is labeled with [15N]ammonium-[15N]nitrate and the total input of airborne N is calculated from the dilution of this tracer by N from the atmosphere. …”
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Honokiol Provides Cardioprotection from Myocardial Ischemia/Reperfusion Injury (MI/RI) by Inhibiting Mitochondrial Apoptosis via the PI3K/AKT Signaling Pathway by Linhua Lv, Qiuhuan Kong, Zhiying Li, Ying Zhang, Bijiao Chen, Lihua Lv, Yubi Zhang

“…Apoptotic levels were detected using terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) staining. Electron microscopy was utilized to identify mitochondrial damage. …”
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Prevalence and Correlates of Hypertension Unawareness among Lebanese Adults: The Need to Target Those “Left Behind” by Fatima Ghaddar, Lama Hammad, Rania A. Tohme, Tamar Kabakian-Khasholian, Nahla Hwalla, Abla M. Sibai

“…Those responding negatively to the face-to-face interview question “whether they had ever been told by a health worker that they have hypertension” were labelled as “apparently healthy.” Results. Overall prevalence of hypertension was 30.7%. …”
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Pharmacological Inhibition of Caspase-1 Ameliorates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation in Mice by Jung-Yeon Kim, Jae-Hyung Park, Kiryeong Kim, Jungmin Jo, Jaechan Leem, Kwan-Kyu Park

“…Administration of Ac-YVAD-cmk inhibited caspase-3 activation as well as caspase-1 activation and attenuated apoptotic cell death, as assessed by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling, in the kidneys of cisplatin-treated mice. …”
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Exploration of different quantitative polymerase chain reaction-based genotyping methods to distinguish Apcmin/+ mice from wildtype mice. by Yuting Sun, Tingyu Zhou, Silin Ye, Effie Yin Tung Lau, Yao Zeng, Jessie Qiaoyi Liang

“…Dual-probe qPCR assays were developed to simultaneously detect mutant and wildtype alleles using differently labelled probes. The genotyping module and delta cycle threshold method were used to facilitate the analysis of results. …”
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Tanshinlactone triggers methuosis in breast cancer cells via NRF2 activation by Wanjun Lin, Zifeng Huang, Xuening Zhang, Dayuan Zheng, Yanchao Yang, Meina Shi, Dongfang Yang, Tong Chu, Wenzhe Ma

“…Fluorescent dyes are used to label macropinosomes and lysosomes. Phase contrast, confocal and transmission electron microscopy were employed to observe cell morphological changes. …”
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