Lack of Hypoxia Inducible Factor-1α Influences on Macrophages Ability to Deal with Leishmania braziliensis In Vitro and Affects Pathology In Vivo by Rodrigo C.O. Sanches, Leonardo G. Vaz, Fabio V. Marinho, Erika S. Guimarães, Edgar M. Carvalho, Lucas P. Carvalho, Sergio C. Oliveira

“…Cutaneous leishmaniasis, caused by Leishmania braziliensis, still represents a serious health problem in Brazil, especially in the northeast region. Currently, to our knowledge, no report describes the role of hypoxia inducible factor-1α (HIF-1α) during L braziliensis infection. …”
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Analisis Kesiapan Penerapan Process Mining pada Sistem Manajemen Pembelajaran Universitas Telkom by Angelina Prima Kurniati, Gede Agung Ary Wisudiawan

“…This paper explores the feasibility of Telkom University LMS usage data to be analysed using process mining. To the best of our knowledge, there was no previous research doing process-based data analytics on this LMS. …”
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Results of replacing fish meal with insect protein in carp feeds by O. Deren, O. Bernakevych, L. Bobeliak, N. Hrytsyshyna, M. Koryliak

“…The application of the knowledge gained in fish farming practice will provide an opportunity to replace traditional feed components with an alternative cheap, affordable and environmentally friendly source of animal protein.…”
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Evaluating user experience in cultural heritage through virtual reality simulations by Shinnu Jangra, Gurjinder Singh, Archana Mantri

“…While previous research has explored the use of digital technologies in museums, there needs to be a greater understanding of VR's effects on user engagement, emotional connection, and knowledge retention within heritage contexts. This study developed a VR-Simulator for the Le-Corbusier Museum, Chandigarh, India, also called VRSLM, and accessed the impact and emotions of participants using the Achievement Emotion Questionnaire (AEQ). …”
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The impact of attitude towards an e-tax system on tax compliance of Vietnamese enterprises: Adoption of an e-tax system as a mediator by Ha Thi Hai Do, Yen Thi Hai Mac, Hoa Thi Van Tran, Thuy Thi Le Nguyen

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Pentavalent Antimonials Combined with Other Therapeutic Alternatives for the Treatment of Cutaneous and Mucocutaneous Leishmaniasis: A Systematic Review by Taisa Rocha Navasconi Berbert, Tatiane França Perles de Mello, Priscila Wolf Nassif, Camila Alves Mota, Aline Verzignassi Silveira, Giovana Chiqueto Duarte, Izabel Galhardo Demarchi, Sandra Mara Alessi Aristides, Maria Valdrinez Campana Lonardoni, Jorge Juarez Vieira Teixeira, Thaís Gomes Verziganassi Silveira

“…A literature review was performed in the databases Web of Knowledge and PubMed in the period from 01st of December 2004 to 01st of June 2017, according to Prisma statement. …”
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Building resilient cattle through better management of buffalo health by Alfredo Sánchez, Merilio Montero

“…However, for it to work, it is necessary to generate a deep knowledge of the animal species, the ecosystem, and the ecological principles of grazing, Capacities that producers must develop. …”
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Spatial deconvolution from bulk DNA methylation profiles determines intratumoral epigenetic heterogeneity by Binbin Liu, Yumo Xie, Yu Zhang, Guannan Tang, Jinxin Lin, Ze Yuan, Xiaoxia Liu, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu

“…The MeHEG algorithm offers novel insights into tumor heterogeneity from an epigenetic perspective, potentially enriching current knowledge of tumor complexity and providing a new tool for clinical and research applications in cancer biology.…”
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Prevalence of dengue and leptospirosis coinfection and associated mortality rates: a systematic review and meta-analysis by Suraj Tiwari, Mahalaqua Nazli Khatib, Rekha MM, Mandeep Kaur, Girish Chandra Sharma, Puneet Sudan, K. Satyam Naidu, Rajesh Singh, Teena Vishwakarma, Sonam Puri, Muhammed Shabil, Anuradha Yadav, Takveer Singh, Sahil Khurana, Rachana Mehta, Prakasini Satapathy, Renu Sah, Abhay M Gaidhane, Ganesh Bushi

“…Methods Adhering the PRISMA 2020 guidelines and registered in the PROSPERO database, we conducted a systematic review and meta-analysis using the PubMed, Embase, and Web of Science databases up to October 2024. Nested Knowledge was used for screening and data extraction. …”
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Evaluating the Cellophane Production Supply Chain Using Multi-Criteria Decision-Making Approaches by َAhmad Jafarnejad, Amir Mohammad Khani

“…This study contributes to the knowledge of SCM since it has elicited how much one needs to understand the market, manage risks, and ensure compliance. …”
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Medical student experiences of Case-Based Learning (CBL) at a multicultural medical school by Catherine Bruen, Jan Illing, Ronan Daly, Frances Meagher, Caroline Delany, Gozie Offiah, Sally Doherty, Ellen Stuart, Martina Crehan, Helen Kelly

“…Abstract Background Educational research highlights active approaches to learning are more effective in knowledge retention and problem-solving. It has long been acknowledged that adapting to more active ways of learning form part of the challenge for new university students as the pedagogical distance between the didactical approach largely followed by secondary school systems the world over differs quite significantly from the often more student-led, critical approach taken by universities. …”
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Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave by Rafael Bielza, Patricia Pérez, Nuria García, Laura Ballesteros-Sanabria, Rosa María Martínez, Azam Ghazi, Clara Hernando, María Victoria Rodríguez, Israel J. Thuissard, Cristina Andreu-Vázquez, José Manuel Bautista

“…While these findings shed light on the knowledge of SIgA-S1, further interdisciplinary studies are warranted to better understand the immune response to SARS-CoV-2 infection.…”
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Lipids in parenteral nutrition – expert consensus statements: Translating guidelines into clinical practice by Robert G. Martindale, Philip C. Calder, Sarah V. Cogle, David C. Evans, Leah Gramlich, Stephen A. McClave, Manpreet S. Mundi, Maurizio Muscaritoli, Reid Nishikawa, Jayshil Patel, Lorenzo Pradelli, Martin Rosenthal, Christian Stoppe, Kelly A. Tappenden, Malissa Warren, Dan Waitzberg, Paul E. Wischmeyer, Stanislaw Klek

“…They assessed the current state of knowledge and developed expert consensus statements regarding the use of lipid emulsions in patients requiring PN. …”
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Global Mountain Safeguard Research (GLOMOS): Five Years Into Action by Stefan Schneiderbauer, Paola Fontanella Pisa, Lina Rodriguez, Navneet Kumar, Federica Romagnoli, Dipesh Chapagain, Jörg Szarzynski

“…The GLOMOS principle is to involve relevant stakeholders and local actors in its work from the beginning of the design phase of projects, recognizing the integration of Indigenous and local knowledge systems as a foundation for risk reduction and the enhancement of climate change adaptation. …”
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Quo vadis autoimmune hepatitis? - Summary of the 5th international autoimmune hepatitis group research workshop 2024Keypoints by Bastian Engel, David N. Assis, Mamatha Bhat, Jan Clusmann, Joost PH. Drenth, Alessio Gerussi, María-Carlota Londoño, Ye Htun Oo, Ida Schregel, Marcial Sebode, Richard Taubert

“…The specific objectives of this year's 5th Workshop were: (1) To further improve diagnostics. (2) Initiate clinical trials including knowledge transfer on drugs from extrahepatic immune-mediated diseases, including B cell-depleting CAR T cells. (3) Utilisation of multi-omics approaches to improve the understanding of disease pathogenesis. (4) Application of machine learning-based approaches established in oncology or transplantation medicine to improve diagnosis and outcome prediction in AIH.…”
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Neuronal cell type specific roles for Nprl2 in neurodevelopmental disorder-relevant behaviors by Brianne Dentel, Lidiette Angeles-Perez, Abigail Y. Flores, Katherine Lei, Chongyu Ren, Andrea Pineda Sanchez, Peter T. Tsai

“…We identify seizures only in the Syn1cre conditional mutant (cKO); hyperactivity, learning difficulties, social deficits, and impulsivity in the Syn1cre and Vgatcre cKOs; and social deficits, and fear learning deficits in L7cre cKOs. To our knowledge, we are the first to describe the behavioral contributions of Nprl2's function across multiple cell types. …”
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Sewage pollution from onsite sewage disposal systems and an offshore wastewater treatment plant outfall in coastal waters of Keaukaha, Hawaiʻi Island by Shayla M.P. Waiki, Steven L. Colbert, Tracy N. Wiegner, Noelani Puniwai, Joseph W.P. Nakoa, III, Nicolas M. Storie, Craig E. Nelson, Ashlynn N. Overly, Karla J. McDermid, Devon K. Aguiar

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Users’ Perspectives of Direct-to-Consumer Telemedicine Services: Survey Study by Kate Churruca, Darran Foo, Andrew Turner, Emily Crameri, Maree Saba, Samantha Spanos, Matthew Vickers, Jeffrey Braithwaite, Louise A Ellis

“…Most participants felt “more in control” (106/128, 82.9%) and “in charge” of their health concern (102/130, 78.5%) when using DTC telemedicine services, in addition to having “more correct knowledge” (92/128, 71.9%) and “feeling better informed as a patient” (94/131, 71.8%). …”
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Mark loss can strongly bias estimates of demographic rates in multi-state models: a case study with simulated and empirical datasets by Touzalin, Frédéric, Petit, Eric J., Cam, Emmanuelle, Stagier, Claire, Teeling, Emma C., Puechmaille, Sébastien J.

“…In this study, we focus on the issue of mark loss and the associated recycling of remarked individuals, which requires further exploration given the increasing use of these models. 2. To fill this knowledge gap, we employed a wide range of simulation scenarios that reflect commonly encountered real case studies, drawing inspiration from the survival rates of 700 vertebrate species. …”
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Specific detection of pigeon parvovirus with TaqMan real-time PCR technology by Cuiteng Chen, Chunhua Zhu, Shuyu Chen, Zhen Chen, Huanru Fu, YuYi Chen, Mengyan Zhang, Wenyu Zhang, Yu Huang, Longfei Cheng, Chunhe Wan

“…Owing to the failure to propagate PiPV in embryos and cells, knowledge of PiPV replication mechanisms in birds still needs further study. …”
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