Short-term survivors with brain metastases have modest benefits from focal and systemic therapies and remain frequent despite improving treatment landscape by M. Czogalla, J. Stöhr, N. Gleim, K. Papsdorf, S. Klagges, P. Hambsch, T. Kuhnt, F. Nägler, A. Barrantes-Freer, J. Wach, N.H. Nicolay, C. Seidel

“…While these lead to considerable survival effects in subgroups, there is limited knowledge about characteristics, prognosticators and treatment effects in patients with BM and short survival. …”
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Transformative agency of students as a resource to form civic consciousness in education system by M. V. Pevnaya, A. N. Tarasova, D. F. Telepaeva, D. S. Protasov

“…University students are more subjective; they do not just formally use resources for civic engagement, but try to accumulate civic knowledge with their help, consciously showing interest and intention in the sphere of such activity. …”
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Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology by Chukwuebuka Egbuna, Vijaykumar K. Parmar, Jaison Jeevanandam, Shahira M. Ezzat, Kingsley C. Patrick-Iwuanyanwu, Charles Oluwaseun Adetunji, Johra Khan, Eugene N. Onyeike, Chukwuemelie Zedech Uche, Muhammad Akram, Mervat S. Ibrahim, Nihal M. El Mahdy, Chinaza Godswill Awuchi, Kaliyaperumal Saravanan, Habibu Tijjani, Uchenna Estella Odoh, Mohammed Messaoudi, Jonathan C. Ifemeje, Michael C. Olisah, Nebechi Jane Ezeofor, Chukwudi Jude Chikwendu, Chinwe Gloria Ibeabuchi

“…The development of nanoparticles requires proper knowledge of their fabrication, interaction, release, distribution, target, compatibility, and functions. …”
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Implementing regional blue economy research and innovation strategies: a case study for the Black Sea by Baris Salihoglu, Baris Salihoglu, Mustafa Yücel, Pinar Uygurer, Ezgi Şahin Yücel, Evangelos Papathanassiou, Devrim Tezcan, Adrian Stanica, Irina Stanciu, Snejana Petrova Moncheva, Nina Dzhembekova, Kremena Blagovestova Stefanova, Viktor Komorin, Tudor Castravet, Kakhaber Bilashvili, Valerian Melikidze, Mamuka Gvilava, Salome Kobaidze

“…The Black Sea is a vital resource with vast potential to boost the societal value of the Blue Economy for its surrounding countries. Improved knowledge and enhanced infrastructure together with better coordination and alignment of research and innovation efforts are critical for the better management of the deteriorated Black Sea ecosystem to help restore and maintain its resilience and enable sustainable use of natural resources. …”
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<i>Miscanthus sinensis ‘Gracillimus’</i> Shows Strong Submergence Tolerance Implying Its Potential Utilization in Construction of Ecological Ditches by Chunqiao Zhao, Ting Wu, Aoxiang Chang, Zhenyu Fan, Xiaona Li, Cui Li, Mei Zheng, Yu Sun, Xiuyun Wan, Jie Meng, Jing Zhang, Zebing Chen, Di Zhao, Qiang Guo, Xincun Hou, Xifeng Fan

“…<i>) Nevski ‘Jingcao No. 2′</i> (Ely), selected from nine species. Despite limited knowledge regarding their tolerance to submergence and responses to this stress, these three grasses were chosen for investigation. …”
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<i>Pleurotus ostreatus</i>: Nutritional Enhancement and Antioxidant Activity Improvement Through Cultivation on Spent Mushroom Substrate and Roots of Leafy Vegetables by Eirini-Maria Melanouri, Ilias Diamantis, Marianna Dedousi, Eleni Dalaka, Paraskevi Antonopoulou, Seraphim Papanikolaou, Ioannis Politis, Georgios Theodorou, Panagiota Diamantopoulou

“…This study also enhances our knowledge by which SMS and RLV influence the NFE2L2/HMOX-1 molecular pathway, thereby affecting specific antioxidant-related genes. …”
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HPGCN: A graph convolutional network-based prediction model for herbal heat/cold properties by Qikai Niu, Jing’ai Wang, Hongtao Li, Lin Tong, Haiyu Xu, Weina Zhang, Ziling Zeng, Sihong Liu, Wenjing Zong, Siqi Zhang, Siwei Tian, Huamin Zhang, Bing Li

“…In this study, we propose an herbal property graph convolutional network (HPGCN) model by combining TCM theory, modern pharmacological mechanisms, prior knowledge of herbal properties, and intelligent algorithms, which can effectively predict herbal heat/cold properties. …”
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Sparse seagrass meadows are critical dugong habitat: A novel rapid assessment of habitat-wildlife associations using paired drone and in-water surveys by Nicole E. Said, Christophe Cleguer, Paul Lavery, Amanda J. Hodgson, Connor Gorham, Julian A. Tyne, Ankje Frouws, Simone Strydom, Johnny Lo, Holly C. Raudino, Kelly Waples, Kathryn McMahon

“…This study provided evidence of critical seagrass habitat, which is important knowledge for the protection and conservation of dugongs and their foraging habitat. …”
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Spatial and temporal heterogeneity of soil respiration in a bare-soil Mediterranean olive grove by S. Aranda-Barranco, S. Aranda-Barranco, P. Serrano-Ortiz, P. Serrano-Ortiz, A. S. Kowalski, A. S. Kowalski, E. P. Sánchez-Cañete, E. P. Sánchez-Cañete

“…<p>Soil respiration (<span class="inline-formula"><i>R</i>_s</span>) is an important carbon flux in terrestrial ecosystems, and knowledge about this CO<span class="inline-formula">₂</span> release process and the drivers involved is a key topic in the context of global change. …”
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Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma by Yining Zhang, Zhenfang Li, Chengchi Zhang, Chengying Shao, Yanting Duan, Guowan Zheng, Yu Cai, Minghua Ge, Jiajie Xu

“…Due to the complex anatomy and the lack of intraoperative modalities to accurately determine the incision margins, surgeons are in a dilemma between extensive tumor removal and improving the quality of patient survival. As more knowledge is gained about HNSCC, the increasing recognition of the value of optical imaging has been emphasized. …”
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Traditional herbal medicine legislative and regulatory framework: a cross-sectional quantitative study and archival review perspectives by Sileshi Dubale, Rashed Edris Usure, Yesuneh Tefera Mekasha, Gemmechu Hasen, Firdos Hafiz, Dereje Kebebe, Sultan Suleman

“…For future roadmaps, 73.8% of respondents believed the government showed a commitment to supporting THM regulation, though 51.9% of participants noted limited knowledge and awareness of THM practices and product regulations. …”
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Optimasi Convolutional Neural Network Untuk Deteksi Covid-19 pada X-ray Thorax Berbasis Dropout by I Gede Totok Suryawan, I Putu Agus Eka Darma Udayana

“…Dengan adanya penetrasi Artificial Intelligence yang tepat pada sistem medis di Indonesia, diharapkan dapat membantu terjadinya transfer knowledge antar paramedis menjadi lebih efektif. Salah satunya dengan menggunakan Deep learning yaitu Convolutional Neural Network (CNN) yang sudah terbukti merupakan salah satu metode yang dapat digunakan untuk melakukan skrining pasien dan mendeteksi COVID-19. …”
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The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity by Tamara M Sirey, Kenny Roberts, Wilfried Haerty, Oscar Bedoya-Reina, Sebastian Rogatti-Granados, Jennifer Y Tan, Nick Li, Lisa C Heather, Roderick N Carter, Sarah Cooper, Andrew J Finch, Jimi Wills, Nicholas M Morton, Ana Claudia Marques, Chris P Ponting

“…Cerox1 is the first lncRNA demonstrated, to our knowledge, to regulate mitochondrial oxidative phosphorylation and, with miR-488-3p, represent novel targets for the modulation of complex I activity.…”
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Genomic and resistome analysis of Salmonella enterica isolates from retail markets in Yichun city, China by Xiaowu Jiang, Abubakar Siddique, Li Chen, Lexin Zhu, Haiyang Zhou, Li Na, Chenghao Jia, Yan Li, Min Yue

“…This study reveals the prevalence of multidrug-resistant and virulent strains of Salmonella serovars in the markets of Yichuan city, posing a risk of human infections. The gained knowledge provided essential baseline information that may be utilized for regular tracking of MDR Salmonella transmission in the food chain to minimize potential future outbreaks.…”
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Black Boarding Academies as a Prudential Reparation by Roy Brooks

“…Moreover, transitional reparations have rarely been attempted in other countries and when tried it has never succeeded to my knowledge. South Africa attempted to use reparations for social transformation. …”
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Modelo de aprendizaje para la selección de un proyecto diseño-construcción (llave en mano) en el sector público A learning model for design-build project selection in the public se... by Alfonso Bastias, Keith R Molenaar

“…This model adjusts parameters and functions using artificial intelligence as the main knowledge engine. This approach can be adapted to many applications of decision support in the design and construction industry.…”
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Bridging the Financial Divide: Factors That Influence Financial Exclusion amongst The Unbanked Population of Botswana by Gaone Geoffrey Seleka

“…The results of this study will add to the body of knowledge in business studies and financial technologies. …”
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Exploring the role of district clinical specialist teams in maternal health outcomes in a South African district: A mixed method study from 2012 to 2020 by J Basu, A Stewart, D Basu, J Wing, U Feucht

“…Within the context of SA district health services, to explore the various obstetric intervention measures undertaken by a DCST over an 8-year period (July 2012 - February 2020), as aligned to the national DCST policy framework, and to document the knowledge and perceptions among managers and health professionals on the work done by the DCST in the district health service. …”
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Cardiovascular function shows early impairment in asymptomatic adolescents diagnosed with type 1 diabetes mellitus: an ultrasound-derived myocardial work study by Martina Ghirardo, Martina Ghirardo, Irene Cattapan, Irene Cattapan, Jolanda Sabatino, Jolanda Sabatino, Alice Pozza, Alice Pozza, Jennifer Fumanelli, Jennifer Fumanelli, Martina Avesani, Joaquin Gutierrez De Rubalcava Doblas, Carlo Moretti, Biagio Castaldi, Giovanni Di Salvo

“…Patients with stage 1 hypertension or a pre-hypertensive state exhibited pathological pulse wave velocities with values exceeding 8 m/s (&gt;99th percentile).ConclusionsTo the best of our knowledge, this was the first study to investigate MW in T1D adolescents. …”
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Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers by Sergio Sánchez-García, Rafael I. Jaén, Roberto Lozano-Rodríguez, José Avendaño-Ortiz, Alejandro Pascual‐Iglesias, Laura Hurtado-Navarro, Eduardo López-Collazo, Eduardo López-Collazo, Lisardo Boscá, Lisardo Boscá, Patricia Prieto, Patricia Prieto, Patricia Prieto

“…Thus, the possible outbreak of new biological diseases in the future makes it necessary to deepen the knowledge of this uncontrolled immune response and look for reliable biomarkers to help us predict its potential health impact. …”
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