Involvement of HMGB1 in Resistance to Tumor Vessel-Targeted, Monoclonal Antibody-Based Immunotherapy by Vito Pistoia, Annalisa Pezzolo

“…HMGB1-induced autophagy promotes tumor resistance to chemotherapy, as shown in different models of malignancy, for example, osteosarcoma, leukemia, and gastric cancer. To the best of our knowledge, there is virtually no information on the relationships between HMGB1 and resistance to immunotherapy. …”
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A Laboratory‐Validated, Graph‐Based Flow and Transport Model for Naturally Fractured Media by Collin R. Sutton, Christopher Zahasky

“…Large graphs over‐describe a fracture plane and act similarly to a porous medium while small graphs oversimplify the solute transport behavior. To our knowledge, this work provides the first validation of graph‐based flow and transport models across a range of experimental conditions and sets the groundwork for upscaling to more complex and computationally efficient fracture models.…”
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Improved Modelling and Assessment of the Performance of Firefighting Means in the Frame of a Fire PSA by Martina Kloos, Joerg Peschke

“…The combination of both tools allowed for an improved modelling of a fire interacting with firefighting means while epistemic uncertainties because lack of knowledge and aleatory uncertainties due to the stochastic aspects of the performances of the firefighting means are simultaneously taken into account. …”
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SIMULATION OF THE PROCESS OF RESEARCH COMPETENCIES FORMATION OF TECHNICAL UNIVERSITIES STUDENTS by GeorgiyM. Maksimovich Il'mushkin, Aleksey G. Il'mushkin

“…The phased development identified in the research competencies with specific professional training of students in technical universities is emphasized. Scientific knowledge is the backbone beginning in technical research, exerting a significant influence on the quality of graduates. …”
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Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis by Jiaona Xu, Yinan Yu, Shijie Li, Fanghui Qiu

“…To assess the direction of amino acid metabolism in T cells and construct related knowledge structure, we performed a bibliometric analysis aiming at amino acid metabolism in T cells utilizing studies publicized in recent 15 years. …”
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BURNOUT RISK OF FOSTER GUARDIAN; AN ANALYSIS OF AVOIDANCE STRATEGIES by M Fuad Badruddin, Hasan Baharun, Imbrotus Solehah

“…The results showed that burnout in foster care could be handled in several ways: ruhul jihad, guardianship mentoring, Knowledge sharing and caregiver advice. The research implies that foster carers must have innovation and creativity in dealing with foster children so that foster carers experience satisfaction in serving students.…”
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Development Trends of Air Flow Velocity Measurement Methods and Devices in Renewable Energy by Paweł Ligęza, Paweł Jamróz, Katarzyna Socha

“…The aim of the article is to familiarize people dealing with renewable energy problems, in particular wind energy, with the current state of knowledge in the field of anemometric measurements, properties of individual types of measuring devices, as well as directions of development of measurement tools. …”
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Cerâmica de tradição islâmica em contexto português by Marco Liberato, Isabel Inácio, Gonçalo Lopes, Constança dos Santos, Jacinta Bugalhão, Helena Catarino, Sandra Cavaco, Jaquelina Covaneiro, Isabel Cristina Fernandes, Ana Sofia Gomes, Susana Gómez, Maria José Gonçalves

“…On the contrary, by valuating the inputs of stratigraphic and contextual data, we verify that continuities do not restrain to the maintenance of technical knowledge, formal patterns or ornamental options. In some latitudes, in the century following the Christian conquest, the pottery production continued to incorporate innovations and tendencies from regions where Muslim powers proceed ruling. …”
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Duloxetine Contributing to a Successful Multimodal Treatment Program for Peripheral Femoral Neuropathy and Comorbid ‘Reactive Depression’ in an Adolescent by Ludmyla Kachko, Shiri Ben Ami, Alon Liberman, Einat Birk, Sefi Kronenberg

“…To the best of the authors’ knowledge, the present article is only the third such report on this dual use of duloxetine in children and adolescents, and the first report of such treatment following femoral neuropathy induced by cardiac catheterization.…”
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Research on How Human Intelligence, Consciousness, and Cognitive Computing Affect the Development of Artificial Intelligence by Yanyan Dong, Jie Hou, Ning Zhang, Maocong Zhang

“…In the future, the research and development of cutting-edge technologies such as brain-computer interface (BCI) together with the development of the human brain will eventually usher in a strong AI era, when AI can simulate and replace human’s imagination, emotion, intuition, potential, tacit knowledge, and other kinds of personalized intelligence. …”
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Le mémoire en formation infirmière en France : exemple d’un dispositif à visée socioconstructiviste by Marielle Boissart

“…However, those results clearly emphasize too, that knowledge can’t possibly be acquired within social interaction alone. …”
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Geopolitical analysis of the collapse of empires by syrous Ahmadi Nohdani, aziz nasirzade, reyhane salehabadi

“…Empires are considered to be powerful entities in the world, and via historical surveys, one can identify several important empires that have existed in different eras. Geopolitical knowledge and its constituent concepts (power, politics, and space) are closely associated with empires and can be explored from this perspective. …”
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Time and frequency domain models for multiaxial fatigue life estimation under random loading by Andrea Carpinteri, Andrea Spagnoli, Camilla Ronchei, Sabrina Vantadori

“…The former methods require the knowledge of the loading time history, and a large number of experimental tests/numerical simulations is needed to obtain statistically reliable results. …”
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La Migration Terminologique Interdisciplinaire dans le Langage Politique Contemporain by Angela GRĂDINARU, Svetlana CEBOTARI

“…In essence, the migration of terminology across disciplines in contemporary political language promotes collaboration, knowledge integration, and a holistic approach to addressing the multifaceted aspects of the modern political landscape.…”
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Adaptive learning in bionics: transforming science education by Nadine Honke, Sebastian Becker-Genschow

“…Data from questionnaires and performance tests assessed prior knowledge, learning success, cognitive activation, and situational interest.ResultsThe findings indicate that 98% of students found digital media motivating, with 81% favoring a hybrid mix of traditional and digital teaching methods. …”
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Differences in Perception of the Participants in the Management Process and Its Real Trajectory by Olaf Flak, Adrian Pyszka

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Partial Nephrectomy in a Patient with a Left Ventricular Assist Device by Jules P. Manger, John A. Kern, Tracey L. Krupski

“…Polytetrafluoroethylene (PTFE) bolsters were misidentified six months postoperatively on computed tomography (CT) at an outside institution as a retained laparotomy sponge. This is, to our knowledge, the first report of a partial nephrectomy performed in a patient with LVAD.…”
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A Case Report of a Pregnancy Complicated by Sigmoid Volvulus in the Extreme Preterm Gestational Age by Naghmeh Kian, Atefeh Moridi

“…In this study, we present a challenging case of a 36‐year‐old pregnant woman with severe abdominal pain and distension that emergently underwent surgery after the diagnosis of sigmoid volvulus without the gestation being discontinued. To our knowledge, our study presents one of the rarest cases of intestinal obstruction during pregnancy that was managed surgically without pregnancy termination. …”
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Development of the program "Method of projects" in the organization of independent work of schoolchildren at the senior stage of learning by Natalia V. Startseva

“…Skills of independent implementation of project activities, knowledge of methods, technologies and strategies of their implementation ensure the training of future specialists of a new generation at the secondary school stage. …”
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Engineering CRISPR for emerging therapeutic applications by Xiaoqi Sun, Zhuang Liu

“…This review summarizes the fundamental knowledge regarding CRISPR–Cas systems and explores the engineering strategies of these versatile systems for novel therapeutic applications. …”
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