Showing 81 - 100 results of 2,046 for search '"kinase"', query time: 0.06s Refine Results
  1. 81
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    Crosstalk between Substrates and Rho-Associated Kinase Inhibitors in Cryopreservation of Tissue-Engineered Constructs by Arindam Bit, Awanish Kumar, Abhishek Kumar Singh, Albert A. Rizvanov, Andrey P. Kiassov, Pradeep Kumar Patra, Munish Kumar, Akalabya Bissoyi

    Published 2017-01-01
    “…Several natural and synthetic materials are extensively used as substrates for tissue engineering constructs and cryopreservation because they promote cell attachment and proliferation. Rho-associated kinase (ROCK) inhibitors can improve the physiological function and postthaw viability of cryopreserved MSCs. …”
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    Article
  3. 83

    Clinical relevance and druggability of sole reciprocal kinase fusions: A large‐scale study by Jiao Feng, Tonghui Ma, Chunyang Wang, Baoming Wang, Qian Liu, Zhengchuang Liu, Houquan Tao, Zaiyuan Ye

    Published 2024-09-01
    “…Abstract Background Building on our prior work that RNA alternative splicing modulates the druggability of kinase fusions, this study probes the clinical significance of sole reciprocal fusions. …”
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  4. 84
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    High Expression of Polo-Like Kinase 1 Is Associated with Early Development of Hepatocellular Carcinoma by Wei Sun, Qi Su, Xiankui Cao, Bin Shang, Aishan Chen, Hongzhuan Yin, Baolin Liu

    Published 2014-01-01
    “…Polo-like kinase 1 (PLK1), one of serine/threonine-protein kinase, has been demonstrated to play pivotal roles in malignant transformation. …”
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  6. 86
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    Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice by Jiayin Zheng, Yue Wang, Song Han, Yanlin Luo, Xiuli Sun, Ning Zhu, Li Zhao, Junfa Li

    Published 2018-01-01
    “…Diabetic encephalopathy is a complication of diabetes mellitus characterized by impaired cognitive functions. Protein kinase C (PKC) isoforms are rarely reported on diabetic encephalopathy, although they have been believed to play crucial roles in other diabetic complications. …”
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    Article
  8. 88
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    Sleep in Genetically Confirmed Pantothenate Kinase-Associated Neurodegeneration: A Video-Polysomnographic Study by Maria Livia Fantini, Giovanni Cossu, Andrea Molari, Monia Cabinio, Ozlem Uyanik, Roberto Cilia, Maurizio Melis, Angelo Antonini, Luigi Ferini-Strambi

    Published 2010-01-01
    “…Pantothenate kinase-associated neurodegeneration (PKAN) is a familial or sporadic disease characterized by extrapyramidal and corticospinal signs with dementia. …”
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  10. 90
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    Functional Characterization of the Canine Heme-Regulated eIF2α Kinase: Regulation of Protein Synthesis by Kimon C. Kanelakis, Jayashree Pyati, Pamela C. Wagaman, Jui Chang Chuang, Young Yang, Nigel P. Shankley

    Published 2009-01-01
    “…Quercetin, a kinase inhibitor known to inhibit mouse and human HRI, inhibits canine HRI in a concentration-dependent manner. …”
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  14. 94
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    Calcium/calmodulin-dependent protein kinase II α and β differentially regulate mammalian sleep by Weiwen Yang, Jingyi Shi, Chenggang Li, Jingqun Yang, Jianjun Yu, Juan Huang, Yi Rao

    Published 2025-01-01
    “…Over the last two decades, protein kinases including Ca2+/calmodulin-dependent protein kinase II (CaMKII) α and β have been implicated in sleep regulation. …”
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    Article
  16. 96

    Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias by Alessandro Morotti, Giovanna Carrà, Cristina Panuzzo, Sabrina Crivellaro, Riccardo Taulli, Angelo Guerrasio, Giuseppe Saglio

    Published 2015-01-01
    “…Here, we review the role of BCR-ABL/protein kinase CK2 interaction in BCR-ABL leukemias, with potentially relevant implications for therapy.…”
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  17. 97
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    Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation by Giuseppe Vassalli, Giuseppina Milano, Tiziano Moccetti

    Published 2012-01-01
    “…The four best-characterized MAPK subfamilies are the c-Jun NH2-terminal kinase (JNK), extracellular signal- regulated kinase-1/2 (ERK1/2), p38 MAPK, and big MAPK-1 (BMK1/ERK5). …”
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  20. 100

    MAP4 kinase-regulated reduced CLSTN1 expression in medulloblastoma is associated with increased invasiveness by Ece Sönmez, Shen Yan, Meng-Syuan Lin, Martin Baumgartner

    Published 2025-01-01
    “…We previously identified CLSTN1 as a putative target of the pro-invasive kinase MAP4K4, which we found to reduce CLSTN1 surface expression. …”
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