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Integrin-Linked Kinase: A Multi-functional Regulator Modulating Extracellular Pressure-Stimulated Cancer Cell Adhesion through Focal Adhesion Kinase and AKT
Published 2009-01-01“…Pressure induces phosphorylation of AKT and focal adhesion kinase (FAK), which are required for pressure-stimulated cancer cell adhesion, but what mediates this effect is unknown. …”
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Immunofluorescence for Detection of TOR Kinase Activity In Situ in Photosynthetic Organisms
Published 2024-12-01“…The target of rapamycin (TOR) is a central hub kinase that promotes growth and development in all eukaryote cells. …”
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Dysfunction of G Protein-Coupled Receptor Kinases in Alzheimer's Disease
Published 2010-01-01“…G protein-coupled receptor kinases (GRKs) are a small family of serine/threonine protein kinases primarily acting at the “receptor-G protein interface”. …”
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Role of Bruton's Tyrosine Kinase in B Cell Development
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An antifouling polydopamine-based fluorescent aptasensor for determination of arginine kinase
Published 2023-05-01“…In this work, a polydopamine (PDA)-based fluorescent aptasensor was developed to detect arginine kinase (AK), one of the major allergens in shellfish. …”
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Diacylglycerol kinase δ is required for skeletal muscle development and regeneration
Published 2025-01-01Subjects: “…diacylglycerol kinase…”
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Eukaryotic Targets of a Bacterial Protein Kinase Virulence Factor
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Protein Kinases and Their Inhibitors in Pluripotent Stem Cell Fate Regulation
Published 2019-01-01“…Protein kinases modulate the reversible postmodifications of substrate proteins to their phosphorylated forms as an essential process in regulating intracellular signaling transduction cascades. …”
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Anti-Inflammatory Effects of Protein Kinase Inhibitor Pyrrol Derivate
Published 2016-01-01“…In our previous studies we showed antitumor and anti-inflammatory activities of protein kinases inhibitor pyrrol derivate 1-(4-Cl-benzyl)-3-Cl-4-(CF3-fenylamino)-1H-pyrrol-2,5-dione (MI-1) on rat colon cancer model. …”
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Diacylglycerol kinase alpha regulates post-hepatectomy liver regeneration
Published 2025-01-01Subjects: “…Diacylglycerol kinase…”
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Curcumin: Synthesis optimization and in silico interaction with cyclin dependent kinase
Published 2017-09-01“…To computationally assess its therapeutic potential against cyclin dependent kinases (CDKs), curcumin was docked in different isoforms of CDKs. …”
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Pantothenate kinase 4 controls skeletal muscle substrate metabolism
Published 2025-01-01“…Here we show that pantothenate kinase 4 (PanK4) is a new conserved exercise target with high abundance in muscle. …”
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Screening for Janus kinase-2 exon 12 mutations among Janus kinase-2 V617F-negative polycythemia vera suspected Iraqi patients
Published 2024-12-01Subjects: “…janus kinase 2 exon 12…”
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An Anaplastic Lymphoma Kinase-positive Inflammatory Myofibroblastic Tumor with Rapidly Acquired Resistance to First-line Anaplastic Lymphoma Kinase Inhibitor: A Case and Literature Review
Published 2024-01-01Subjects: “…anaplastic lymphoma kinase inhibitor…”
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Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
Published 2025-02-01“…We also discovered that CDK8/CDK19 affect splicing, a novel means by which Mediator kinases control gene expression. To further probe Mediator kinase function, we completed cytokine screens and metabolomics experiments. …”
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Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases
Published 2017-01-01“…Rho-associated kinase (Rho-kinase/ROCK) was originally identified as an effector protein of the G protein Rho. …”
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Sphingosine Kinase 1 – A Therapeutic Opportunity for Alleviating Liver Fibrosis?
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Personal glucose meter-based portable method for creatine kinase assay
Published 2025-03-01Subjects: Get full text
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Receptor-like Kinase GOM1 Regulates Glume-Opening in Rice
Published 2024-12-01“…Map-based cloning and subsequent complementation tests confirmed that GOM1 encodes a receptor-like kinase (RLK). <i>GOM1</i> was expressed in nearly all floral tissues, with the highest expression in the lodicule. …”
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