The Role of Cytokines in Nephrotic Syndrome by Elham Ahmadian, Yalda Rahbar Saadat, Elaheh Dalir Abdolahinia, Milad Bastami, Mohammadali M. Shoja, Sepideh Zununi Vahed, Mohammadreza Ardalan

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Protective Effect of CXCR3+CD4+CD25+Foxp3+ Regulatory T Cells in Renal Ischemia-Reperfusion Injury by Cao Jun, Li Qingshu, Wei Ke, Li Ping, Dong Jun, Luo Jie, Min Su

“…Numbers of Tregs were increased at 72 h after reperfusion in kidney. PC61 mAb preconditioning decreased the numbers of Tregs and aggravated kidney injury. …”
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Effect of long-term serum sodium levels on the prognosis of patients on maintenance hemodialysis by Siyu Chen, Bin Pan, Xiaowei Lou, Jianghua Chen, Ping Zhang

“…Abnormal serum Na (SNa) levels are common in patients with chronic kidney disease (CKD) which is associated with increased morbidity and mortality. …”
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Light-chain proximal tubulopathy: a retrospective study from a single Chinese nephrology referral center by Xin Wang, Xiao-juan Yu, Su-xia Wang, Fu-de Zhou, Ming-hui Zhao

“…One patient presented with acute kidney injury and 16 patients presented with chronic kidney disease. …”
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Effects of Oral L-Carnitine Supplementation on Lipid Profile, Anemia, and Quality of Life in Chronic Renal Disease Patients under Hemodialysis: A Randomized, Double-Blinded, Placeb... by Afsoon Emami Naini, Mahnaz Moradi, Mojgan Mortazavi, Asghar Amini Harandi, Mehdi Hadizadeh, Farhad Shirani, Hamed Basir Ghafoori, Pardis Emami Naini

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Complement Factor H Gene Variant in a Patient with Thrombotic Microangiopathy on a Mixed Clinical Background by Yoichi Iwafuchi, Tetsuo Morioka, Yuko Oyama, Shin Goto, Ichiei Narita

“…However, she was in poor general condition and did not get the consent of her family, so no invasive searches such as a kidney biopsy were performed. Despite the cause of acute kidney insufficiency being unclear, she was transferred to us for maintenance hemodialysis. …”
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Gender disparity in living organ donation: a qualitative analysis of experiences and perceptions of female donors in Pakistan by Muhammad Ishaq, Javeria Saleem, Ruhma Binte Shahzad, Mahrukh Iqbal, Abida Tehreem, Raja Sajjad Asghar, Aleena Touqeer, Gul Mehar Javaid Bukkhari

“…Objectives This study aims to explore and analyse the interplay of sociocultural, psychological and institutional factors, gender roles and power dynamics in shaping the decision-making processes and experiences of living kidney and liver donors in Punjab, specifically focusing on women.Design This study employed a qualitative approach, using in-depth interviews to delve into the narratives and experiences of living kidney and liver donors in Punjab.Setting Punjab Human Organ Transplantation Authority (PHOTA), Lahore, Punjab, Pakistan.Participants 17 participants registered at the PHOTA for kidney or liver donation.Results Interviews with living donors at PHOTA, Lahore, provided qualitative data, which was then systematically coded and analysed to identify recurring themes that explore the underlying social and cultural reasons for the observed gender disparity. …”
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Amelioration of Nephrotoxicity in Mice Induced by Antituberculosis Drugs Using Ensete ventricosum (Welw.) Cheesman Corm Extract by Abebe Dukessa Dubiwak, Urge Gerema, Daba Abdisa, Ebsa Tofik, Wondu Reta

“…The group of mice treated with an EVCE reinstated those derangements. The kidney section of Group-II mice showed an abnormality in kidney structure; however, these deformities were not detectable in group-IV mice. …”
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Deceased Donor Renal Transplantation Combined with Bilateral Nephrectomy in a Patient with Tuberous Sclerosis and Renal Failure by R. Novotny, J. Chlupac, T. Marada, S. Bloudickova-Rajnochova, H. Vavrinova, L. Janousek, J. Fronek

“…Patient was placed on the “cadaverous kidney transplant waiting list”. Method. Computed tomography angiography revealed symptomatic PSA in the right kidney angiomyolipoma (AML). …”
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Macrocystic Adult Penile Lymphangioma: A Rare Presentation by Jaisukh Kalathia, Kaushal Patel, Santosh Agrawal

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Effect of Aerobic Treadmill Exercise Regulating Glucose Transporter 9 on Renal Function in Hyperuricemia Rats by LIANG Jiarong, YANG Huan, CUN Yongdan, WANG Lihuan, LI Yijie, YE Bin

“…Hematoxylin-eosin (HE) was used to stain the renal histopathological section, and the microscope (×400) was used to observe the structural changes of renal tubules and glomerulus; the peroxidase method was used to detect the renal function indexes such as uric acid (UA), creatinine (Cre) and urea nitrogen (BUN); enzyme-linked immunosorbent assay (ELISA) method was used to determine the contents of interleukin-1β (IL-1β) in serum and kidney tissues; Western blot was used to detect the expressions of Caspase-1, IL-1β and glucose transporter 9 (GLUT-9) in the kidney tissues.Results① Pathological examination results: there was not obvious pathological changes were observed in the kidney tissues of the Control group; in the Model group, the renal tissue capsule was incomplete, the glomerulus was deformed and atrophic, and the renal tubules were disordered; in the Exercise group, the number of inflammatory cell infiltration was significantly decreased, the renal tubular structure was relatively intact, and the pathological changes such as cytoplasmic vacuolation of renal tubular epithelial cells were significantly decreased. ② UA, Cre and BUN content of serum: compared with the Control group, UA, BUN and Cre content in serum of the Model group and Exercise group was significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, UA, BUN and Cre content in serum of the Exercise group were significantly decreased (<italic>P</italic>&lt;0.05). ③ Serum and kidney IL-1β content: compared with the Control group, the expression of IL-1β in serum and kidney of the Model group and the Exercise group were significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, the expression of IL-1β in serum and kidney of the Exercise group was significantly decreased (<italic>P</italic>&lt;0.05). ④ Expressions of Caspase-1, IL-1β and GLUT-9 protein: compared with the Control group, the expressions of Caspase-1, IL-1β and GLUT-9 protein in kidney tissues of the Model group and the Exercise group were significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, the expressions of Caspase-1, IL-1β, and GLUT-9 protein in kidney tissues of the Exercise group were significantly decreased (<italic>P</italic>&lt;0.05).ConclusionAerobic treadmill exercise can effectively reduce the level of uric acid and inflammatory response of hyperuricemia rats, and improve renal function, which may be related to the regulation of GLUT-9 protein expression.…”
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Theoretical Construction and Clinical Application of "Flaccidity Caused by Deficiency and Congestion" of Osteoporosis by YAO Xinmiao

“…Based on the basic theories such as "kidney governing bone" and "kidney deficiency", professor YAO Xinmiao of The Third Affiliated Hospital of Zhejiang Chinese Medical University creatively put forward the pathogenic theory of "flaccidity caused by deficiency and congestion" of OP, which holds that the pathogenesis of OP is the combination of deficiency and blood stasis, mixed with impotence. …”
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ROS-ERK Pathway as Dual Mediators of Cellular Injury and Autophagy-Associated Adaptive Response in Urinary Protein-Irritated Renal Tubular Epithelial Cells by Jian-kun Deng, Xueqin Zhang, Hong-luan Wu, Yu Gan, Ling Ye, Huijuan Zheng, Zebing Zhu, Wei Jing Liu, Hua-feng Liu

“…What is more, ERK inhibitor U0126 could decrease the release of neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), and the number of apoptotic cells induced by urinary proteins, indicating the damaging effects of ERK pathway in mediating cellular injury and apoptosis in HK-2 cells. …”
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Diet with high content of advanced glycation end products induces oxidative stress damage and systemic inflammation in experimental mice: protective effect of peanut skin procyanid... by Li Zhao, Xingxing Zhang, Langzhi He, Yubing Li, Yue Yu, Qun Lu, Rui Liu

“…The expression of advanced glycation product receptor (RAGE) was also significantly increased in liver and kidney (P &lt; 0.05). PSP could not only effectively reduce the accumulation of AGEs in serum, liver and kidney of mice, but also reduce the expression of RAGE in liver and kidney of mice. …”
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Renal Transplantation in Secondary Amyloidosis Associated with Tuberculosis by Vivek B. Kute, Aruna V. Vanikar, Himanshu V. Patel, Manoj R. Gumber, Pankaj R. Shah, Pranjal R. Modi, Hargovind L. Trivedi

“…She was transplanted with kidney from her 28-year-old brother with 3/6 human leukocyte antigen match. …”
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TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation by Agnieszka Loboda, Mateusz Sobczak, Alicja Jozkowicz, Jozef Dulak

“…Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic kidney diseases. Increased apoptosis, epithelial-to-mesenchymal transition, and inflammatory cell infiltration characterize the injured kidney. …”
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Donor-Recipient Size Mismatch in Paediatric Renal Transplantation by J. Donati-Bourne, H. W. Roberts, R. A. Coleman

“…End stage renal failure in children is a rare but devastating condition, and kidney transplantation remains the only permanent treatment option. …”
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The Prevention of the Renal Chronic Damage: a Priority from Childhood by Aymahara Gómez Morejón, Lidia Rosa Pérez González, Ortelio Chaviano Mendoza, Jan O’neil González Ramos, Juan Carlos Yanes Macías, Annia Quintana Marrero

“…<strong>Background:</strong> chronic kidney disease in children has become a serious public health problem, it implies a high risk of mortality that increases over the years, its early recognition allows to act on risk factors and prevent their progression to terminal stages. …”
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Attempted Depletion of Passenger Leukocytes by Irradiation in Pigs by Hao-Chih Tai, Xiaocheng Zhu, Yih Jyh Lin, Hidetaka Hara, Mohamed Ezzelarab, Michael Epperley, Mubina A. Quader, David K. C. Cooper

“…In Study 1, we attempted to deplete leukocytes from potential kidney “donor” pigs, using two regimens of total body irradiation. …”
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Glomerular Filtration Result in Patients with Hypertensive Emergencies by Manuel Tasis Hernández, Wendy Talavera Hernández, Valentina Edighill Villanueva, Aliucha María Rodríguez Díaz, Taimy Calvera Castro, Juan Francisco Gastón Del Monte

“…<strong>Foundation</strong>: hypertensive emergencies may be the presentation of an underlying chronic kidney disease; in turn kidney damage may be the cause that leads to hypertensive emergency. …”
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