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4001
Acute Oral Toxicity, Histopathological Analysis, and Antimalarial Potential of Jatropha tanjorensis Leaf Extracts
Published 2024-12-01“…Histopathological analysis of the livers and kidneys of mice exposed to the extracts was performed using standard protocols. …”
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4002
Awareness About Diabetes And Its Complications Among Patients With Diabetes Mellitus
Published 2023-12-01“…Moreover, Patients with longer diabetes duration were more likely to visit ophthalmologists at regular intervals (P value 0.023). 111 (56%) never checked their urine for proteinuria and 172 (86%) were aware that diabetes can affect their kidneys. Foot care and awareness of diabetic foot complications were lacking among patients. 48 (24%) examined their feet daily, 66 (33%) never examined their feet, and 73 (36%) were never told about foot care by their doctors. …”
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4003
Renal impairment as a risk factor for chemotherapy induced neutropenia in the treatment of trifluridine/thymidine phosphorylase inhibitor plus bevacizumab
Published 2025-01-01“…As TPI is excreted by the kidneys, the risk of adverse events is likely to be high in patients with an impaired renal function. …”
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4004
Radiopharmacokinetic modelling and radiation dose assessment of 223Ra used for treatment of metastatic castration-resistant prostate cancer
Published 2021-06-01“…The highest absorbed dose coefficients were found for bone endosteum, liver and red marrow, followed by kidneys and colon. Conclusion The biokinetic modelling of 223Ra and its progeny may help to predict their distributions in patients after administration of Xofigo®. …”
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4005
Immunohistochemical Expression of FOXP3+ Regulatory T Cells in Proteinuric Primary Glomerulopathies
Published 2021-01-01“…Data about FOXP3+ Tregs’ presence and role in primary glomerulopathies of native kidneys are minimal. We comparatively studied the immunohistochemical expression of FOXP3+ Tregs, CD4+ and CD3+ T cells in IgA nephropathy (IgAN), focal segmental glomerulosclerosis (FSGS), and membranous glomerulopathy (MGN). …”
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4006
Effect of Chromium Picolinate and Chromium Nanoparticles Added to Low- or High-Fat Diets on Chromium Biodistribution and the Blood Level of Selected Minerals in Rats
Published 2022-07-01“…The additional dietary Cr, irrespective of its form and diet type, was not accumulated in the analyzed internal organs, i.e. brain, spleen, kidneys, liver, thigh bone, and thigh muscle. It should be stressed that dietary CrPic, unlike CrNPs, added to the high-fat diet adversely reduced plasma concentration of vital minerals in comparison to the levels observed in rats fed the low-fat diet, i.e. …”
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4007
Save a trip: Clinical outcomes of cardiac allografts recovered by local surgeons compared to recipient center surgeons.
Published 2025-02-01“…Background: Local surgeon recovery of donor livers and kidneys is common and well-studied. This practice is rare and poorly studied in cardiac transplantation. …”
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4008
aDolescent and prEconception health peRspectiVe of Adult Non-communicable diseases (DERVAN): protocol for rural prospective adolescent girls cohort study in Ratnagiri district of K...
Published 2020-09-01“…The following investigations will be performed: body composition by anthropometry and bioimpedence, and blood pressure, fasting blood sample to measure glucose, insulin, lipids, micronutrients and hormones, abdominal ultrasonography to measure liver, pancreas and kidneys.A biorepository has been created for long-term storage of blood, urine and saliva samples for future analysis. …”
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4009
Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection
Published 2016-01-01“…At 6 months euthanasia was performed. Kidneys were processed for histopathology and immunohistochemistry (semiquantitative). …”
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4010
Cytokines and Water Distribution in Anorexia Nervosa
Published 2021-01-01“…Underlying mechanisms are unclear but may involve a loss of water from the gut, kidneys, or skin due to AN-associated inflammatory processes.…”
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4011
Multimodality imaging features of systemic amyloidosis: a case report
Published 2025-01-01“…Organs involved include heart, kidneys, gastrointestinal tract and nervous system, stage III of mayo 2012 model. …”
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4012
Evaluation of [Cu]Cu-DOTA and [Cu]Cu-CB-TE2A Chelates for Targeted Positron Emission Tomography with an αβ-Specific Peptide
Published 2009-03-01“…Significantly, both 64 Cu-labeled tracers showed unexpectedly high and persistent levels of radioactivity in the kidneys (> 40% injected dose/g at 4 and 12 hours postinjection). …”
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4013
Influence of B16/F10 melanoma growth variant on calcium levels in mitochondria in various organs of female mice
Published 2021-03-01“…At the initial stage of CNP‑stimulated tumor growth, a decrease in calcium in the mitochondria of the skin by 5.7 times and its accumulation in the mitochondria of the brain by 6.6 times, heart, and kidneys were recorded by 1.5 times. At the terminal stage of stimulated melanoma growth, extremely low calcium values were recorded in the mitochondria of all organs. …”
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4014
Effective treatment of severe acute pancreatitis and COVID-19 pneumonia with tocilizumab
Published 2020-09-01“…The highest ACE 2 expression was found in alveolar cells of the lungs [7], but also in the heart, kidneys, and gastrointestinal tract, including the pancreas. …”
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4015
Biodistribution of a Mitochondrial Metabolic Tracer, [18F]F-AraG, in Healthy Volunteers
Published 2022-01-01“…The highest uptake was observed in the kidneys and liver, while the brain, lung, bone marrow, and muscle showed low tracer uptake. …”
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4016
Artificial neural networks analysis predicts long-term fistula function in hemodialysis patients following percutaneous transluminal angioplasty
Published 2024-06-01“…Kidney failure is particularly common in the United States, where it affects over 700,000 individuals. …”
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4017
Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations
Published 2025-01-01“…The toxicity study revealed that the mice’s behavior, body weight, and organ weights (liver and kidneys) were unaffected by Ferula communis leaf extract administration compared to controls. …”
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4018
PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database
Published 2025-01-01“…The comparative Reporting Odds Ratios (ROR) for AR, between PD1 and PDL1 inhibitors, was calculated.ResultsWe gathered 159 AR involving an ICI, especially nivolumab (73, 45.9%), mostly affecting kidneys (87, 54.7%). Median time to onset: 28 days. …”
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4019
Simultaneous Determination of Multiple Active Components from Bushen Pills and Application in a Pharmacokinetic Study in Rats
Published 2020-01-01“…Bushen Pills (BSPs), as a traditional Chinese medicine (TCM), is widely used in clinic to enrich Yang, nourish Yin, stem essence, and strengthen kidneys. Two chromatographic methods, liquid chromatography-mass spectrometry (LC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS), were applied to analyze the multiple active components of BSPs in dosage form for quality evaluation and in rat plasma for pharmacokinetics study, respectively. …”
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4020
Ozone Therapy on Rats Submitted to Subtotal Nephrectomy: Role of Antioxidant System
Published 2005-01-01“…In this animal model of CRF, ozone rectal administrations produced a delay in the advance of the disease, protecting the kidneys against vascular, hemorheological, and oxidative mechanisms. …”
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