Bioinformatics analysis of miRNAs germacrone protection on diabetic nephropathy by Binqi Wang, Wenfang He, Zhixuan Xie, Jinshi Zhang, Yan Ren, Qiang He, Juan Jin

“…Additionally, we established a DN mice model, which was treated with germacrone, to investigate how it altered the miRNA transcriptome in mice kidneys. RNA sequencing was also performed on the DN mice model with and without germacrone pre-treatment. …”
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PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice by Ying Sun, Zhanjun Jia, Gang Liu, Li Zhou, Mi Liu, Baoxue Yang, Tianxin Yang

“…The present study was undertaken to investigate the regulation of PGE2 synthetic pathway and the interaction between peroxisome proliferator-activated receptor (PPAR)γ and PGE2 synthesis in the kidneys of db/db mice. Strikingly, urinary PGE2 was remarkably elevated in db/db mice paralleled with the increased protein expressions of COX-2 and mPGES-1. …”
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Fatal Renal Failure in a Spinal Cord Injury Patient with Vesicoureteric Reflux Who Underwent Repeated Ureteric Reimplantations Unsuccessfully: Treatment Should Focus on Abolition o... by Subramanian Vaidyanathan, Bakul Soni, Kottarathil Abraham Abraham, Peter Hughes, Gurpreet Singh

“…A 29-year-old man developed paraplegia at T-10 level due to road traffic accident in 1972. Both kidneys were normal and showed good function on intravenous urography. …”
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Mesenchymal Stem Cells Attenuate Cisplatin-Induced Nephrotoxicity in iNOS-Dependent Manner by Bojana Simovic Markovic, Marina Gazdic, Aleksandar Arsenijevic, Nemanja Jovicic, Jovana Jeremic, Valentin Djonov, Nebojsa Arsenijevic, Miodrag L. Lukic, Vladislav Volarevic

“…MSC treatment significantly attenuated influx of leukocytes, macrophages, dendritic cells (DCs), neutrophils, CD4+ T helper (Th), and CD8+ cytotoxic T lymphocytes (CTLs) in damaged kidneys and attenuated the capacity of renal-infiltrated DCs, CD4+ Th, and CD8+ CTLs to produce TNF-α and IL-17. …”
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Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice by Ziyi Xiong, Qiling Kong, Juan Hua, Qi Chen, Dandan Wang

“…The main target organs of NP accumulation are the lungs, liver, heart, and kidneys. However, compared with that for other target organs, research on the adverse effects of NPs on the heart is limited. …”
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Investigation of children's toys quality on the Macedonian market: determination of lead, cadmium and chromium levels by Mirvete Abdullahi1, Suzana Angelova, Evgenija Kiroska Petreska, Tatjana Kadifkova Panovska

“…Lead in children's toys originates from toxic lead dyes and can lead to serious health complications of central nervous system, cardiovascular, immune system and kidneys. Toys like finger paints had increased values of cadmium, but insignificantly higher compared to MML. …”
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Selenium-enriched and ordinary green tea extracts prevent high blood pressure and alter gut microbiota composition of hypertensive rats caused by high-salt diet by Meirong Wu, Xiaobin Wu, Jiangxiong Zhu, Fanglan Li, Xinlin Wei, Yuanfeng Wang

“…Our results showed that GT and Se-GT supplementations significantly prevented the increase of blood pressure (BP), activated the phosphoinosmde-3-kinase/protein kinase B (PI3K/Akt) signaling pathway, and regulated the gene expression related to BP, as well as improved the tissue damage like heart, liver, and kidneys. Besides, the key parameters associated with oxidative stress, inflammation and endothelial dysfunction were also altered by GT and Se-GT treatments. …”
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Clinical characteristics of female Fabry disease patients with hypertrophic cardiomyopathy with mid-ventricular obstruction by Natsuko Inagaki, Yasuyoshi Takei, Tsuguhisa Hatano, Yasuyuki Takada, Yoshinao Yazaki, Hisanori Kosuge, Masatake Kobayashi, Shinji Suzuki, Tomohiro Umezu, Masahiko Kuroda, Kazuhiro Satomi, Takeharu Hayashi

“…The loss or reduced activity of GLA leads to damage to multiple organs, resulting in the intracellular accumulation of globotriaosylceramide in various organs, including the heart, kidneys, and nervous system. Pathological changes in the heart typically result in concentric left ventricular hypertrophy. …”
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Studying dynamic changes in body mass and mass of internal organs in laboratory rats experimentally infected with bovine leukosis virus by E. S. Krasnikova, R. V. Radionov, A. V. Krasnikov, A. Yu. Svetozarova

“…The reverse trend was observed for such internal organs of the experimental animals as liver, spleen, kidneys and lungs. At first, their relative mass decreased to some extent, then increased with different dynamics in groups. …”
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Efficacy and safety of an herbal galactagogue decoction versus powdered formulation in lactating rats by Pruksa Chotitham, Suksalin Booranasubkajorn, Saracha Pattanapholkornsakul, Pravit Akarasereenont, Pinpat Tripatara

“…Both PNF decoction and powder did not exhibit subacute toxicity to the liver and kidneys in maternal rats and pups. Conclusion: The effectiveness of the PNF decoction in improving both milk production and prolactin levels was similar to that of domperidone. …”
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MANF overexpression ameliorates oxidative stress-induced apoptosis of human nucleus pulposus cells by facilitating mitophagy through promoting MFN2 expression by Liang Ma, Xiangyu Meng, Tuerhongjiang Abudurexiti, Yuntao Liu, Jiang Gao, Weibin Sheng

“…MANF has been shown to promote mitophagy in murine kidneys; however, its role in IDD remains unexplored. …”
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Development of [F]FPy-WL12 as a PD-L1 Specific PET Imaging Peptide by Wojciech G. Lesniak PhD, Ronnie C. Mease PhD, Samit Chatterjee PhD, Dhiraj Kumar PhD, Ala Lisok MA, Bryan Wharram MS, Venkateswara Rao Kalagadda PhD, Leisha A. Emens MD, PhD, Martin G. Pomper MD, PhD, Sridhar Nimmagadda PhD

“…The majority of [ 18 F]FPy-WL12 radioactivity was localized in the tumors, liver, and kidneys indicating the need for optimization of the labeling strategy to improve the in vivo pharmacokinetics of the radiotracer.…”
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Deer antler velvet (Cervus elaphus sibiricus) promotes fracture healing via partial BMP2-Smad mediated osteoblast differentiation by Ji Hyang Gu, Min-Young Chae, Jeong June Choi, Thanh Chu Duc, Chang Gue Son, Eun-Jung Lee

“…Abstract Background Cervus elaphus Sibiricus (CES) has been traditionally used in Korean clinics to promote fracture healing based on its function of tonifying the kidneys and strengthening bones. However, experimental data supporting its efficacy are still insufficient. …”
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Pathogenicity of tick-derived lymphocytic choriomeningitis virus in BALB/c mice by Ziyan Liu, Xiaojie Liang, Liang Li, Ning Liu, Zedong Wang, Feng Wei

“…Pathological lesions were identified in most organs within 5 dpi except for the kidneys and testicles. Interferon gamma (IFN-γ) level was significantly elevated during the early stage of infection and returned to baseline levels within 10 days. …”
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The problem of rare tumors in gynecology: a clinical case of benign retroperitoneal sclerosing pelvic pecoma in 49-year-old woman by V. I. Lanchinsky, Yu. V. Chushkov, A. B. Ponomarev, Yu. I. Osmanov, A. I. Ishchenko, N. V. Vorobev

“…It is marked, that there is also a possibility of pecoma`s localization in various organs, for example, lungs, liver, kidneys, as well as in soft tissues. The possibility of multiple lesions – pecomatosis is emphasized. …”
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Harmful impacts of microplastic pollution on poultry and biodegradation techniques using microorganisms for consumer health protection: A review by Mohamed E. Abd El-Hack, Elwy A. Ashour, Fatemah AlMalki, Asmaa F. Khafaga, Mahmoud Moustafa, Mohammed O. Alshaharni, Islam M. Youssef, Ahmed A. Elolimy, Sylwester Świątkiewicz

“…In poultry, microplastics negatively affect production and harm vital organs such as the kidneys, spleen, and lungs. In humans, exposure to microplastics can lead to inflammation, immune responses, metabolic disturbances, DNA damage, neurological damage, and even cancer upon contact with mucosal membranes or absorption into the body. …”
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Effects of Cholecalciferol on Key Components of Vitamin D-Endo/Para/Autocrine System in Experimental Type 1 Diabetes by Anna Mazanova, Ihor Shymanskyi, Olha Lisakovska, Lala Hajiyeva, Yulia Komisarenko, Mykola Veliky

“…Cholecalciferol administration countered the impairments of the vitamin D-endo/para/autocrine system in the kidneys and extrarenal tissues of diabetic rats. Conclusions. …”
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Atlas of Fshr expression from novel reporter mice by Hongqian Chen, Hui-Qing Fang, Jin-Tao Liu, Shi-Yu Chang, Li-Ben Cheng, Ming-Xin Sun, Jian-Rui Feng, Ze-Min Liu, Yong-Hong Zhang, Clifford J Rosen, Peng Liu

“…The genetic decoding of the widespread pattern of Fshr expression highlights its physiological relevance beyond reproduction and fertility, and opens new avenues for therapeutic options for age-related disorders of the bones, lungs, kidneys, and hearts, among other tissues. Exploiting the power of the Fshr knockin reporter animals, this report provides the first comprehensive genetic record of the spatial distribution of FSHR expression, correcting a long-term misconception about Fshr expression and offering prospects for extensive exploration of FSH-FSHR biology.…”
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Giant Hydatid Cyst Originating From Psoas Muscle Extending to the Iliac Bone: A Case Report by Mohammad Hadi Niakan, Fatemeh Mirparsa, Hamid Zaferani Arani, Sedighe Hooshmandi, Elham Peyravi

“…ABSTRACT Hydatid cysts, caused by the Echinococcus granulosus parasite, predominantly affect the liver and lungs, but can also impact other organs such as the kidneys, brain, and muscles. Infection occurs when individuals ingest eggs from contaminated food or water, leading to cyst formation primarily in the liver. …”
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Factors Predicting Renal Function Outcome after Augmentation Cystoplasty by Shahbaz Mehmood, Raouf Seyam, Sadia Firdous, Waleed Mohammad Altaweel

“…The causes of renal deterioration were noncompliance to self-catheterization (2 patients), posterior urethral valve/dysplastic kidneys (2 patients), and reflux/infection (2 patients). …”
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