The Current Status and Advance in Treatment of Glycogen Storage Disease Type Ⅰb by JIANG Jingjing, MA Mingsheng

“…Most subtypes can lead to increased glycogen accumulation in tissues of the liver, muscles, kidneys etc. GSD type Ⅰ (GSDⅠ) is the most common type of the liver glycogen storage diseases that are caused by a deficiency in glucose-6-phosphatase in the liver, kidneys, and intestines. …”
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Appeal of Editor-in-Chief by No authors

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Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome by Jan Soukop, Ludmila Kazdová, Martina Hüttl, Hana Malínská, Irena Marková, Olena Oliyarnyk, Denisa Miklánková, Soňa Gurská, Zuzana Rácová, Martin Poruba, Rostislav Večeřa

“…In contrast, the hypertriglyceridemia-induced ectopic storage of lipids in muscles, the heart, and kidneys reduced glucose utilization in muscles and was not affected. …”
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Central and nephrogenic diabetes insipidus: updates on diagnosis and management by Kathryn Flynn, Jennifer Hatfield, Kevin Brown, Nicole Vietor, Thanh Hoang

“…Inability to respond to or produce ADH leads to inability of the kidneys to reabsorb water, resulting in hypotonic polyuria and, if lack of hydration, hypernatremia. …”
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Epithelioid Angiomyolipoma of Liver with an Inflammatory Component: A Case Report by Jyothi C. R., Dhanya P. Menon, Joy Augustine, A. K. Abdul Siyad

“…Angiomyolipomas (AMLs) are benign mesenchymal tumors seen in kidneys in association with tuberous sclerosis. They are uncommon in liver. …”
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Influence of Chronic Alcohol Use on Osteoblastic Differentiation of Bone Marrow Cells, Bone Properties, and Hepatic and Renal Morphology of Rats by Michelle Cardoso de Sousa, Mariana Raquel da Cruz Vegian, Matheus Alves Biserra, Bruno César Almeida Costa, Samira Esteves Afonso Camargo, Sigmar de Mello Rode, Carolina Judica Ramos, Luciane Dias de Oliveira, Luana Marotta Reis de Vasconcellos

“…However, significant changes in the liver and kidneys and adverse effects on the mechanical properties of the tibia were observed. …”
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Tribbles 3 Regulates the Fibrosis Cytokine TGF-β1 through ERK1/2-MAPK Signaling Pathway in Diabetic Nephropathy by Luwei Zhang, Jinhang Zhang, Xinnong Liu, Shengli Liu, Jun Tian

“…The expression of TRB3, TGF-β1, and collagen type IV was increased in kidneys of db/db diabetic mice. TGF-β1 and collagen type IV regulated by high glucose through ERK1/2 MAPK were downregulated by silencing TRB3 in renal mesangial cells. …”
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Vasopressin Antagonists and Dilutional Hyponatremia by D Mohamed Babatin, Samuel S Lee

“…Hyponatremia of less than 130 mmol/L occurs in 30% of cirrhotic patients (1), and is mainly due to the reduced capacity of their kidneys to excrete free water.…”
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Tissue tropism and clinical manifestation of chicken infectious bronchitis (review) by Ali Dandal Shebli, V. V. Makarov

“…It is regarded generally as a respiratory system disease; different strains of chicken infectious bronchitis virus can demonstrate variability of tissue tropism and affect reproductive organs as well as kidneys with severe effects. Some virus strains propagate in intestines but without pathological changes.…”
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Construction and Radiolabeling of Adenovirus Variants that Incorporate Human Metallothionein into Protein IX for Analysis of Biodistribution by Lei Liu, Buck E. Rogers, Natalia Aladyshkina, Bing Cheng, Stephen J. Lokitz, David T. Curiel, J. Michael Mathis

“…Similar to the imaging results, most of the radioactivity was found in the liver, spleen, kidneys, and bladder, with significant differences between the groups observed in the liver. …”
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The Protective Effect of Lidocaine on Septic Rats via the Inhibition of High Mobility Group Box 1 Expression and NF-κB Activation by Huan-Liang Wang, Yan-Qiu Xing, Ying-Xue Xu, Fei Rong, Wei-Fu Lei, Wen-Hua Zhang

“…In this study, we investigated the effect of lidocaine treatment on serum HMGB1 level and HMGB1 expression in liver, lungs, kidneys, and ileum in septic rats induced by cecal ligation and puncture (CLP). …”
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Systemic Candida parapsilosis Infection Model in Immunosuppressed ICR Mice and Assessing the Antifungal Efficiency of Fluconazole by Yu’e Wu, Fangui Min, Jinchun Pan, Jing Wang, Wen Yuan, Yu Zhang, Ren Huang, Lixin Zhang

“…Postmortem and histopathological examinations presented fugal-specific lesions in multiorgans, especially in kidneys, characterized by inflammation, numerous microabscesses, and fungal infiltration. …”
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Clinical Practice Guidelines for Hypertensive Emergency Treatment by Carlos Garcia Gomez, Raúl Nieto Cabrera

“…It has been defined as the abrupt increase of systolic and diastolic blood pressure (usually ≥ 220/140 mmHg) associated with organic damage mainly of the central nervous system, heart or kidneys. This document includes concepts, different presentations, diagnosis and treatment, stressing the function of the most frequent hypotensive medications. …”
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An Emerging Pulmonary Haemorrhagic Syndrome in Dogs: Similar to the Human Leptospiral Pulmonary Haemorrhagic Syndrome? by R. Klopfleisch, B. Kohn, S. Plog, C. Weingart, K. Nöckler, A. Mayer-Scholl, A. D. Gruber

“…Leptospira could not be cultured post mortem from the lungs or kidneys. However, Leptospira-specific PCR was positive in lung, liver or kidneys of three dogs. …”
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Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus by Ozgur Kanat, Veysel Soydal Ataseven, Ilke Evrim Secinti, Veli Incecik, Firat Dogan

“…In contrast, no positivity was observed in the kidneys and heart.<p> <b>Conclusion: </b>It is anticipated that the data obtained on small ruminant lentivirus infections will have an important place in goat breeding and will be important for new studies and control programs that may be developed.…”
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A Low-Protein Diet Enhances Angiotensin II Production in the Lung of Pregnant Rats but Not Nonpregnant Rats by Haijun Gao, Daren Tubianosa Tanchico, Uma Yallampalli, Chandrasekhar Yallampalli

“…Plasma angiotensin II, expressions of Ace and Ace2, and activities of these proteins in lungs, kidneys, and plasma were measured. These parameters were compared among nonpregnant rats or between nonpregnant and pregnant rats fed different diets. …”
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Novel Heterozygous Mutations in JAG1 and NOTCH2 Genes in a Neonatal Patient with Alagille Syndrome by Alisa Brennan, Anil Kesavan

“…We describe a case of ALGS with novel mutations of JAG1 and NOTCH2 genes in a newborn girl with complex congenital heart disease, bilateral dysplastic kidneys, and malrotation with volvulus.…”
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THE ALGORITHM OF DETERMINATION OF EYE FUNDUS VESSELS BLOOD FLOW CHARACTERISTICS ON VIDEOSEQUENCE by O. V. Nedzvedz, S. V. Ablameyko, A. M. Nedzved, A. V. Glinsky, G. M. Karapetyan, A. A. Anisimov, I. B. Gurevich, V. V. Yashina

“…Such characteristics allow to determine blood flow changes in the microvasculature affecting the blood flow in the brain, kidneys and coronary vessels. Developed algorithm includes four stages: the video sequence stabilization, the vessels segmentation with the help of a neural network, the determination of the instantaneous velocity in the vessels based on the optical flow and the analysis of the results.…”
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The APOA1 p.Leu202Arg variant potentially causes autosomal recessive cardiac amyloidosis by Shusuke Yagi, Ryosuke Miyamoto, Masayoshi Tasaki, Hiroyuki Morino, Ryuji Otani, Muneyuki Kadota, Takayuki Ise, Hiroki Yamazaki, Kenya Kusunose, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Daiju Fukuda, Mitsuharu Ueda, Masataka Sata

“…Abstract ApoA-I amyloidosis is an extremely rare form of systemic amyloidosis that commonly involves the heart, kidneys, and liver. ApoA-I amyloidosis is caused by amyloidogenic variants of APOA1 that are inherited in an autosomal dominant manner. …”
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Lung Transplantation in a Patient with COPA Syndrome by Jorge M. Mallea, Anna Kornafeld, Andras Khoor, David B. Erasmus

“…COPA syndrome is a newly discovered, rare genetic autoimmune disorder, which can affect the lungs, joints, and kidneys. It is difficult to recognize, and the survival benefit of lung transplantation for these patients is not yet known. …”
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