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3782
γδ T Cells’ Role in Donor-Specific Antibody Generation: Insights From Transplant Recipients and Experimental Models
Published 2025-01-01“…Analysis of a cohort of 331 kidney transplant recipients found no relation between the number of circulating γδ T cells and the risk to develop DSA. …”
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3783
FGF21 ameliorates diabetic nephropathy through CDK1-dependently regulating the cell cycle
Published 2025-01-01“…To investigate the mechanism of action of FGF21 in the treatment of glycolytic kidney, transcriptome sequencing of renal tissues and KEGG pathway enrichment analysis of differential genes were performed.ResultsThe study’s findings demonstrated that FGF21 intervention increased clotting time, decreased oxidative stress and inflammation, and avoided thrombosis in addition to considerably improving glomerular filtration damage. …”
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3784
Systematic review: characteristics of myocarditis followed by fixed drug eruption and dry eye syndrome in patients who have been vaccinated with monkeypox in children and adults
Published 2025-01-01“…MPOX infection shares clinical similarities with smallpox but can cause complications like myocarditis, anorectal pain, ocular lesions, kidney damage, or soft tissue superinfection. The study aims to understand the characteristics of myocarditis, fixed drug eruption, and dry eye syndrome in Monkeypox patients.MethodsThis review was conducted based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), and the Cochrane Handbook for Systematic Reviews of Interventions. …”
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3785
Unveiling the toxicity of JWH-018 and JWH-019: Insights from behavioral and molecular studies in vivo and vitro
Published 2025-01-01“…In the present study, we aimed to investigate the toxicity and underlying mechanisms of indole SCs JWH-018 and JWH-019 in mice (C57BL/6, male, 6–8 weeks old), zebrafish (AB strain, male, 4–5 months old) and modified human embryonic kidney (HEK) 293 T cells, using behavioral, pharmacokinetic, pharmacological approaches, and molecular docking. …”
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3787
Effects of Density Stress on Growth and Physiology of Epinephelus fuscoguttatus ♀×Epinephelus lanceolatus ♂
Published 2025-02-01“…Before testing the corresponding indicators, the brain, liver, intestine, stomach, and kidney were frozen in liquid nitrogen. The results showed that the optimum stocking density of pearl gentian grouper was (15.48–29.67) kg/m3 under the conditions of water [temperature (27±2) ℃, dissolved oxygen (8.0±1.0) mg/L, pH 7.8, and salinity 24±1]. …”
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3788
Serum NFL and neuropsychological performance over ∼8 years in women with and without HIV: a longitudinal repeated measures studyResearch in context
Published 2025-02-01“…The MWCCS is funded primarily by the National Heart, Lung, and Blood Institute (NHLBI), with additional co-funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Aging (NIA), National Institute of Dental and Craniofacial Research (NIDCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), National Institute of Nursing Research (NINR), National Cancer Institute (NCI), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute on Deafness and Other Communication Disorders (NIDCD), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute on Minority Health and Health Disparities (NIMHD), and in coordination and alignment with the research priorities of the National Institutes of Health, Office of AIDS Research (OAR). …”
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3789
Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway
Published 2025-02-01“…Introduction: Vascular calcification, a devastating vascular complication accompanying atherosclerotic cardiovascular disease and chronic kidney disease, increases the incidence of adverse cardiovascular events and compromises the efficacy of vascular interventions. …”
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3790
Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inf...
Published 2025-01-01“…Many of these patients develop forms of acute kidney injury, heart or acute liver failure during intensive care. …”
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3791
Characteristics of adherent and non-adherent patients with hypertension in a Norwegian cross-sectional study
Published 2025-02-01“…Exclusion criteria were dementia, substance or alcohol abuse, pregnancy, terminal illnesses, poor Norwegian language skills, or severe kidney failure [glomerular filtration rate (GFR) < 30 mL/min/1.73 m2]. …”
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3792
Cardiovascular risk assessment: Missing albuminuria contributing to gender inequality
Published 2025-01-01“…Introduction: Chronic kidney disease (CKD) is associated with high cardiovascular disease (CVD) risk, and requires specific interventions to decreases CVD risk.The guidelines indicate that systematic global CVD risk assessment is recommended in individuals with any major vascular risk factor. …”
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3793
Cardiovascular risk assessment: Missing albuminuria contributing to gender inequality
Published 2025-01-01“…Introduction: Chronic kidney disease (CKD) is associated with high cardiovascular disease (CVD) risk, and requires specific interventions to decreases CVD risk.The guidelines indicate that systematic global CVD risk assessment is recommended in individuals with any major vascular risk factor. …”
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3794
Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2<small.letters>dmepda</small.letters>H<mml:math> <mml:mrow>...
Published 2006-01-01“…The dimethyl sulphoxide(DMSO) soluble complexes (<bold>1</bold>)–(<bold>4</bold>) and (<bold>6</bold>) were assessed for their cancer chemotherapeutic potential towards hepatocellular carcinoma and kidney adenocarcinoma cell lines. The 1,10-phenanthroline containing complex [Cu(2dmepda)(phen)<mml:math> <mml:mrow> <mml:msub> <mml:mrow> <mml:mrow><mml:mrow> <mml:mrow><mml:mo>(</mml:mo> <mml:mrow><mml:msub> <mml:mtext>H</mml:mtext> <mml:mn>2</mml:mn> </mml:msub> <mml:mtext>O</mml:mtext> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow> </mml:mrow> <mml:mo>]</mml:mo></mml:mrow> </mml:mrow> <mml:mn>2</mml:mn> </mml:msub> </mml:mrow> </mml:math>0.5phen (<bold>3</bold>) was the most potent with activity that compares well to that of <emph>cis</emph>platin.…”
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3795
Evidence-based incorporation of key parameters into MELD score for acute-on-chronic liver failure
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3796
Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024
Published 2025-01-01“…AN UNSUPERVISED LEARNING TOOL FOR STEM CELL BURDEN ASSESSMENT IN THE PRETERM KIDNEY • M. Fraschini, V. Fanos, L. Didaci, G. Faa (Cagliari, Italy; Philadelphia, Pennsylvania, USA) ABS 25. …”
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Protective Effects of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, against Cisplatin-Induced Nephrotoxicity in Mice
Published 2017-01-01“…Gemigliptin attenuated cisplatin-induced apoptotic cell death, as assessed by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling and Western blot analysis in the kidneys. Gemigliptin also decreased the plasma levels of tumor necrosis factor-α and monocyte chemoattractant protein-1 and attenuated nuclear staining of nuclear factor kappa-B p65 in the kidneys. …”
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The DnaJ-Hsp70-Hsp90 co-chaperon networks in scallops under toxic Alexandrium dinoflagellates exposure
Published 2025-01-01“…CfDnaJs’ up-regulation in kidneys was similar with that in hepatopancreas, while their down-regulation was stronger in kidneys than in hepatopancreas, with CFA.38965.19.DNAJC30 being continuously down-regulated in both tissues of the two algae exposure. …”
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Pathological investigations on theileriosis caused by theileria annulata in brown calves
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