Nonlinear associations of the hs-CRP/HDL-C index with metabolic dysfunction-associated steatotic liver disease and advanced liver fibrosis in US adults: insights from NHANES 2017–2... by Bin Liang, Xue Qiu, Jiansheng Huang, Yequan Lu, Hairong Shen, Jianchao Ma, Yongyu Chen

“…Additionally, significant interactions were observed between MASLD and covariates such as gender, smoking status, chronic kidney disease (CKD), and cancer. Similarly, the hs-CRP/HDL-C index exhibited positive correlations with advanced liver fibrosis across diverse subgroups, with notable interactions related to cancer. …”
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Prevalence of complications and comorbidities associated with obesity: a health insurance claims analysis by Jay P. Bae, David R. Nelson, Kristina S. Boye, Kieren J. Mather

“…Disorders such as obstructive sleep apnea, osteoarthritis, type 2 diabetes, metabolic dysfunction-associated steatotic liver disease, coronary heart diseases (CHD), and chronic kidney diseases also exhibited substantial burden among those with obesity. …”
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Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis by Flora Magno de Jesus Oliveira, Cassiano Felippe Gonçalves-de-Albuquerque, Isabel Matos Medeiros de Moraes, Patrícia Alves Reis, Vinicius Novaes Rocha, Patrícia Torres Bozza, Adriana Ribeiro Silva, Hugo Caire de Castro Faria Neto

“…One single administration of simvastatin 6 h after CLP was able to prevent both liver and kidney dysfunction. In addition, this drug decreased cell accumulation in the peritoneum as well as the levels of TNF-α, MIF, IL-6, and IL-1β. …”
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Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein by Paula Andréa Malveira Cavalcante, Natalia Alenina, Alexandre Budu, Leandro Ceotto Freitas-Lima, Thaís Alves-Silva, Juan Sebastian Henao Agudelo, Fatimunnisa Qadri, Niels Olsen Saraiva Camara, Michael Bader, Ronaldo Carvalho Araújo

“…Macrophages contribute to a continuous increase in blood pressure and kidney damage in hypertension, but their polarization status and the underlying mechanisms have not been clarified. …”
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Understanding the Spectrum of Mild Clinical Outcomes and Novel Findings in Arterial Tortuosity Syndrome Among Qatari Patients: Implications of SLC2A10 Mutation by Muhammed Riyas K. Rahmath, Haytham Ibrahim, Muhammad Faiyaz-Ul-Haque, Zafar Nawaz, Ahmad Zitoun, Ahmed Hussein, Ahmed Sadek, Ayman El-Menyar, Reema Kamal, Hassan Al-Thani, Gulab Sher

“…Novel features such as a flat philtrum, bulbous noses, bilateral nasolacrimal duct obstruction, allergic conjunctivitis, latent nystagmus, café au lait spots, eczema, dermatitis, allergic reactions, bilateral temporomandibular joint cysts, bilateral syndactyly (toes), parapelvic cysts, kidney malrotation, vesicoureteral reflux, and nephrolithiasis were identified in our cohort. …”
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The Impact of Complete Revascularization in Symptomatic Severe Left Ventricular Dysfunction between Coronary Artery Bypass Graft and Percutaneous Coronary Intervention by Hsiu-Yu Fang, Yen-Nan Fang, Yin-Chia Chen, Jiunn-Jye Sheu, Wei-Chieh Lee

“…There was no significant difference in the incidence values of in-hospital course and those of in-hospital mortality, acute kidney injury, and postprocedural hemodialysis. There was no significant difference in the 1-yearfollow-up of recurrent MI, revascularization, or stroke between the groups. …”
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Spot Urine Estimations Are Equivalent to 24-Hour Urine Assessments of Urine Protein Excretion for Predicting Clinical Outcomes by Boon Wee Teo, Ping Tyug Loh, Weng Kin Wong, Peh Joo Ho, Kwok Pui Choi, Qi Chun Toh, Hui Xu, Sharon Saw, Titus Lau, Sunil Sethi, Evan J. C. Lee

“…The use of spot urine protein to creatinine ratios in estimating 24 hr urine protein excretion rates for diagnosing and managing chronic kidney disease (CKD) predated the standardization of creatinine assays. …”
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Angioembolization performed by trauma surgeons for trauma patients: is it feasible in Korea? A retrospective study by Soonseong Kwon, Kyounghwan Kim, Soon Tak Jeong, Joongsuck Kim, Kwanghee Yeo, Ohsang Kwon, Sung Jin Park, Jihun Gwak, Wu Seong Kang

“…The indications for trauma surgeon–performed angiography included significant hemorrhage from liver injury, pelvic injury, splenic injury, or kidney injury. We assessed the angiography results according to the operator of the initial angiographic procedure. …”
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Rice endosperm and bran proteins ameliorate diabetic osteoporosis in Zucker Diabetic Fatty rats by Masatoshi Kubota, Shogo Sugaki, Erika Komori, Reiko Watanabe, Yuki Higuchi, Yukikazu Harada, Hiroyuki Hashimoto, Shinobu Fujimura, Motoni Kadowaki

“…The rats exhibited an early stage of diabetic nephropathy and chronic kidney disease–mineral and bone disorder, and parameters reflecting mineral and bone metabolism and bone structure and strength were evaluated. …”
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Lipid nephrotoxicity mediated by HIF-1α activation accelerates tubular injury in diabetic nephropathy by Zebo Hu, Qianwen Zhu, Ying Wang, Xue Deng, Hui Yang, Mingjun Zhou, Jiyuan Zhang, Hao Wang, Haosen Wang, Lin Wang, Cui Zhang, Shu Li

“…This study is intended to explore the effect of hypoxia-inducible factor-1α (HIF-1α) activation on lipid accumulation in the diabetic kidney. A type 1 diabetic rat model was established by STZ intraperitoneal injection. …”
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Food nutrition and toxicology targeting on specific organs in the era of single-cell sequencing by Xiaofei Wang, Xiaowen Cheng, Huiling Liu, Xiaohuan Mu, Hao Zheng

“…ScRNA-seq applications has been summarized on three typical organs (brain, liver, kidney), and two representative immune- and tumor related health problems. …”
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The Plasma Soluble Urokinase Plasminogen Activator Receptor Is Related to Disease Activity of Patients with ANCA-Associated Vasculitis by Fei Huang, Yueqiang Li, Ranran Xu, Anying Cheng, Yongman Lv, Qingquan Liu

“…The soluble urokinase plasminogen activator receptor (suPAR) is associated with kidney diseases and is used as a prognostic factor of renal function progression. …”
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The relationship between thiamin, folic acid and cognitive function in a rat model of uremia by Yifei Lu, Chenqi Xu, Kewei Xie, Bingru Zhao, Minzhou Wang, Cheng Qian, Xuemei Chen, Leyi Gu, Wangshu Wu, Renhua Lu

“…The Morris water maze was used to assess the cognitive function eight weeks post-surgery, and serum levels of thiamin, folic acid and homocysteine were detected subsequently. Brain and kidney tissues were collected for pathological examination and 8-Hydroxy-2’-deoxyguanosine (8-OHdG) immunochemistry staining. …”
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Association between normal weight obesity and comorbidities and events of cardiovascular diseases among adults in South China. by Miaomiao Ma, Deliang Lv, Xiaobing Wu, Yuqing Chen, Shimiao Dai, Yutian Luo, Hui Yang, Wei Xie, Fengzhu Xie, Qinggang Shang, Ziyang Zhang, Zhiguang Zhao, Ji-Chang Zhou

“…The cardiovascular comorbidities being studied were abdominal obesity (AO), diabetes, hypertension, dyslipidemia, metabolic syndrome, and chronic kidney disease, while the CVD events were occurrences of myocardial infarction and strokes. …”
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Optimalisasi Strategi Intelijen dalam Menghadapi Ancaman TPPO Jaringan Kamboja dan Implikasinya bagi Keamanan Nasional by Gidion Jhon Putra

“…The results show that kidney organ trafficking and the exploitation of non-procedural Indonesian Migrant Workers (PMI) as online scammers represent the latest modus operandi of human trafficking and transnational crimes that violate human dignity. …”
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Physically engineered extracellular vesicles targeted delivering miR-21-5p to promote renoprotection after renal ischemia-reperfusion injury by Di Wu, Wenjie Ma, Liucheng Wang, Chengcheng Long, Silin Chen, Jingyu Liu, Yiguan Qian, Jun Zhao, Changcheng Zhou, Ruipeng Jia

“…Acute kidney injury (AKI) resulting from ischemia-reperfusion injury (IRI) is a common challenge in various clinical practices, yet effective therapies remain elusive. …”
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Utilization of cardiopulmonary bypass at radical nephrectomy for renal cell carcinoma with tumour thrombus by Chalairat Suk‐Ouichai, Mitchell M. Huang, Clayton Neill, Christopher K. Mehta, Ashley E. Ross, Shilajit D. Kundu, Kent T. Perry Jr, Duc T. Pham, Hiten D. Patel

“…Conclusions Surgical extirpation of kidney tumours with associated TT remains the standard of care among patients with locally advanced RCC. …”
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Human cytomegalovirus (HCMV) trends in Sri Lanka: insights from a hospital-based seroprevalence analysis by Narapity Pathirannehalage Sunil-Chandra, Madawala Vithanage Madusha Lakmali Jayasundara, Maththe Gama Ralalage Shobha Sanjeewani Gunathilaka, Suduwa Dewage Himal Suminda

“…Methods A total of 820 blood samples obtained from 820 participants of selected low and high-risk populations in Sri Lanka, namely; hospital inpatients (n = 200), antenatal women (n = 80), blood donors (n = 80), cancer patients (n = 200), Sexually Transmitted Disease (STD) clinic attendees (n = 160) and Chronic Kidney Disease (CKD) patients on haemodialysis (n = 100) were tested for IgG antibodies against HCMV by Enzyme Linked Immunosorbent Assay (ELISA). …”
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The SGLT-2 Inhibitors and their Role in the Treatment of Heart Failure - A Review of Literature by Silvia Ciraolo, Agnieszka Kulczycka-Rowicka, Joanna Wojda, Katarzyna Lesiczka-Fedoryj, Anna Walczak, Zuzanna Kościuszko, Adam Sobiński, Matylda Czerwonka, Katarzyna Kurza, Julianna Podolec

“…Key mechanisms include natriuresis, improved cardiac metabolism, reduced inflammation, prevention of cardiac remodeling, sympathetic inhibition, enhanced vascular health, and better kidney function. • Conclusions: The benefits of SGLT2 inhibitors extend beyond glucose control. …”
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New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis by Sameh A. Abdelnour, Walaa M. Essawi, Nasser Ghanem, Ibrahim T. El-Ratel, Abdel-Wahab A. Abdel-Warith, Elsayed M. Younis, Ahmed N. F. Neamat-Allah, Shimaa A. Amer, Simon J. Davies, Ali Ali El-Raghi

“…ASG treatment significantly improved liver and kidney functions. The concentration of haptoglobin, tumour necrosis factor-alpha (TNF-α), and Malondialdehyde (MDA) was significantly lower in the treated group (4.42 mg/dl, 68.89 pg/ml, 3.46 nmol, respectively) than in the control group (8.29 mg/dl, 83 pg/ml, 6.23 nmol, respectively). …”
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