Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years by Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan

“…Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. …”
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Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis by Ankit Agrawal, MD, Sharmeen Sorathia, MD, Umesh Bhagat, MD, Salman Zahid, MD, Aro Daniela Arockiam, MD, Aqieda Bayat, MD, Ahmad Safdar, MD, Akiva Rosenzveig, MD, Muhammad Majid, MD, Sanya Chandna, MD, Rahul Gupta, MD, Brittany Weber, MD, PhD, Erin D. Michos, MD, MHS

“…Pregnant patients with psoriasis had a higher incidence of complications during delivery, including preeclampsia/eclampsia, acute kidney injury, pulmonary edema, cardiac arrhythmias, and venous thromboembolism compared to those without psoriasis. …”
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Tc99m-DTPA Study to Validate an Experimental Model of Ureteral Obstruction in Rabbits: Preliminary Results by Marcelo Lopes de Lima, Rodolfo Bertti, Juliano César Moro, Fábio Coltro Neto, Ricardo Miyaoka, Adriano Fregonesi, Mariana da Cunha Lopes de Lima, Celso Darío Ramos

“…Surgery procedure provided unilateral ureteral obstruction (left kidney) to urinary flow and posteriorly was evaluated by Tc99m-DTPA renal scintigraphy and histopathological study. …”
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The role of diet therapy in insulin resistance in women with polycystic ovary syndrome by H.B. Semenyna, T.V. Fartushok, N.V. Fartushok, N.Ya. Dumanchuk, O.M. Yurchyshyn

“…The study did not include pregnant, lactating women who took hormonal therapy and/or insulin sensitizers during the last 2 months, had liver, kidney, and heart diseases that failed local treatment of hirsutism, with congenital hyperplasia of the adrenal glands, androgen-secreting tumors, Cushing's syndrome. …”
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Prognostic role of aetiological agent vs. clinical pattern in candidates to lead extraction for cardiac implantable electronic device infections by Giulia Massaro, Renato Pascale, Mauro Biffi, Cristian Martignani, Matteo Ziacchi, Andrea Simeone, Raimondo Pittorru, Manuel De Lazzari, Federico Migliore, Igor Diemberger

“…S. aureus was isolated in 32.5% of patients, and it was more associated with valvular heart disease, systemic infection, and chronic kidney disease. CIEDI pattern was associated with 1-year mortality, with a significantly worse outcome in patients with “cold closed pocket” (CCP). …”
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Rapid corticosteroid taper versus standard of care for immune checkpoint inhibitor induced nephritis: a single-center retrospective cohort study by Ryan Sullivan, Riley Fadden, Kerry L Reynolds, Meghan D Lee, Harish Seethapathy, Ian A Strohbehn, Sophia H Zhao, Genevieve M Boland, Meghan E Sise

“…Fifteen (56%) of patients were rechallenged with ICIs, and only two (13%) developed recurrent nephritis.Conclusions Patients with ICI-induced nephritis have excellent kidney outcomes when treated with corticosteroids that are tapered over 3 weeks.…”
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Poor Glycemic Control in Carbapenem-Resistant Klebsiella pneumoniae Infections: Impact on Epidemiological Features, Mortality Risks, and Polymyxin Resistance by Wang Q, Yan T, Ma C, Teng X, Shen C, Wang N, Yu K, Chu W, Zhou Q, Liu Z

“…Three clinically isolated CRKP strains were used to investigate the effect of glucose on bacterial capsule synthesis and the impact on bacterial resistance to polymyxin and serum killing.Results: Patients with poor glycemic control experienced more severe infections and had a higher likelihood of chronic kidney disease (CKD) and acute renal insufficiency compared to those with good glycemic control. …”
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First results of the EuroHeart program by András Jánosi, Zoltán Járai

“…One in five patients (20.2%) had a history of heart attack, 6.2% had a stroke. Abnormal kidney function was confirmed in 7.5% of patients. …”
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Internal Dosimetry in Patients Undergoing Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-[DOTA0-Tyr3] Octerotate: A Single-Center Experience by Elahe Mahmoudi, Mahasti Amoui, Mohammad Reza Deevband, Elahe Pirayesh, Mohammad Reza Asgari, Mehdi Ghorbani

“…Results: Mean calculated dose in the kidney and liver were obtained as 0.30-0.82 mGy/ MBq, and 1.05-2.11 mGy/MBq, respectively. …”
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Isolation and Characterization of Coronavirus and Rotavirus Associated with Calves in Central Part of Oromia, Ethiopia by Umer Seid, Fufa Dawo, Asamino Tesfaye, Munera Ahmednur

“…All samples (7) of ELISA test positive of both coronavirus and rotavirus were propagated in Madin-Darby bovine kidney (MDBK) cells. After 3 subsequent passages, progressive cytopathic effect (CPE), i.e., rounding, detachment, and the destruction of monolayer cell of five samples (1 sample of coronavirus and 4 samples of rotavirus) (71.4%) were observed. …”
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The Optimum Dietary Phenylalanine Requirement of Hybrid Grouper (Epinephelusfuscoguttatus ♀ × Epinepheluslanceolatus ♂) Juveniles: Effects on Growth Performance, Gut Micromorpholog... by Pinxian Yang, Haijiao Wang, Lei Ma, Haoran Yin, Zhanying Zhu, Cong Liu, Wei Huang, Zhiyu Zhou, Xiaoyi Wu, Sehrish Taj

“…In addition, fish fed Phe 10.1 had lower levels of nuclear factor erythroid 2 (Nrf2) and heat shock protein 70 (HSP70) in the head kidney, and Cu/Zn-superoxide (Cu/ZnSOD) dismutases in the midgut compared to fish fed other Phe levels. …”
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Exploring healthcare workers’ immunisation behaviour towards COVID-19 vaccines through psychological patterns by Nour El Houda Benkaddour, Sara Ramdani, Hind Khalil, Asmae Lekfif, Naima Abda, Bouchra Oneib, Yassamine Bentata

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Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK by Tim Doran, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Siobhan Reilly, Claire Planner, Ivan Olier, Linda Gask

“…For both groups, most conditions were more prevalent in more deprived areas, whereas for the SMI group conditions such as hypothyroidism, chronic kidney disease and cancer were more prevalent in more affluent areas.Conclusions Our findings highlight the health inequalities faced by people with SMI. …”
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ZINQ-L: a zero-inflated quantile approach for differential abundance analysis of longitudinal microbiome data by Shuai Li, Runzhe Li, John R. Lee, John R. Lee, Ni Zhao, Wodan Ling

“…Its comprehensive examination of the abundance distribution enables the identification of heterogeneous associations, improving the testing power.ResultsExtensive simulation studies and an application to a real kidney transplant microbiome study demonstrate the improved power of ZINQ-L in detecting true signals while controlling false discovery rates.ConclusionZINQ-L is a zero-inflated quantile-based approach for detecting individual taxa associated with outcomes or exposures in longitudinal microbiome studies, providing a robust and powerful option to improve and complement the existing methods in the field.…”
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Determinants of Diabetic Nephropathy among Diabetic Patients in General Public Hospitals of Tigray, Ethiopia, 2018/19 by Teklewoini Mariye Zemicheal, Degena Bahrey Tadesse, Hagos Tasew Atalay, Girmay Teklay Weldesamuel, Gebrewahd Bezabh Gebremichael, Haben Nuguse Tesfay, Teklehaimanot Gereziher Haile

“…Unmanaged diabetic nephropathy is one of the most leading causes of kidney failure. There is a scarcity of information on the determinants of diabetic nephropathy among diabetes mellitus patients in Ethiopia. …”
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Emergency Laparotomy in the Critically Ill: Futility at the Bedside by Niels D. Martin, Sagar P. Patel, Kristen Chreiman, Jose L. Pascual, Benjamin Braslow, Patrick M. Reilly, Lewis J. Kaplan

“…Preoperative lactate levels were higher in nonsurvivors (2.7 vs. 8.5 mmol/L, p<0.001), as was vasopressor use (62.5% vs. 97.5%, p<0.001), acute kidney injury (51.6% vs. 72.5%, p<0.01), leukocytosis (53.1% vs. 71.3%, p<0.04), and anemia (45.3% vs. 71.3%, p<0.01). …”
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Miramistin effect on BHK-21 and PSGK-30 cell line proliferation and FMD virus reproduction in these cells by M. I. Doronin, D. A. Lozovoy, V. V. Pronin, D. V. Mikhalishin, V. A. Starikov, A. V. Borisov, A. A. Shishkova

“…Since many types of mycoplasmas affect the genitourinary system organs, to assess the cytotoxicity of Miramistin kidney mammalian cells of various mammals can be used as test systems, in particular, the newborn Syrian hamster (VNK-21), Siberian mountain ibex (PSGK-30), and others. …”
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Upregulation of GSTP1 mediated by chimeric TFE3 promotes TFE3-tRCC progression by targeting JNK signaling pathway by Weixu Chen, Mengtong Wu, Lin Du, Changhua Fang, Hao Wang, Wendi Wang, Chengwei Zhang, Hongqian Guo, Gutian Zhang

“…Abstract Background TFE3-translocation renal cell carcinoma (TFE3-tRCC), a distinct subtype of kidney cancer characterized by Xp11.2 translocations, involving TFE3 fusion with various partner genes, lacks effective treatments and prognostic biomarkers for advanced stages. …”
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Comparing the Prognostic Value of Lactate to the Neutrophil to Lymphocyte Ratio Among Sepsis Patients: A Prospective Cohort Study by Bou Chebl R, Haidar S, Kattouf N, Assaf M, Alwan JS, Khamis MM, Abdeldaem K, Makki M, Tamim H, Abou Dagher G

“…No significant differences were found in AUCs between lactate and NLR in patients with septic shock, Lactate< 2, Lactate≥ 2, diabetes, malignancy, chronic kidney diseases, other sources of infection, albumin ≥ 30 and age ≥ 65.Conclusion: In this study, lactate but not NLR was associated with in-hospital mortality. …”
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Secondary Cancer after Androgen Deprivation Therapy in Prostate Cancer: A Nationwide Study by Jae Heon Kim, Gi Hwan Bae, Jaehun Jung, Tae Il Noh

“…The ADT group showed lower risks of overall cancer-specific incidence for stomach, colon/rectum, liver/inflammatory bowel disease (IBD), gall bladder/extrahepatic bile duct, lung, bladder, and kidney cancers than the non-ADT group. When the duration of ADT was more than 2 years of ADT, the ADT group showed higher risk of cancer-specific incidence for brain and other CNS cancers but lower risk of cancer-specific incidence for liver/ IBD and lung cancers than the non-ADT group. …”