CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy by Jing Zhao, Hong-liang Rui, Min Yang, Li-jun Sun, Hong-rui Dong, Hong Cheng

“…In animal experiments, the ORG mice developed proteinuria, podocyte injury, and hypertriglyceridemia, accompanied with deregulated lipid metabolism, renal ectopic lipid deposition, activation of NOD-like receptor protein 3 (NLRP3) inflammasome, and secretion of IL-1β of the kidney. The expression of adipose differentiation-related protein (ADRP), CD36, sterol regulatory element-binding protein 1 (SREBP-1), and peroxisome proliferator-activated receptor α (PPARα) in renal tissue were increased. …”
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Application of the new ‘XU-line’ in the dynamic ultrasonographic evaluation of the spatial displacement of anterior cervical tissues for airway management: protocol for a prospecti... by Mao Xu, Yang Zhou, Yujie Wang, Mingfeng Mao, Wanrui Shi

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Angiographic and Clinical Impact of Novel Revascularization for Occluded Femoropopliteal Prosthetic Bypass Graft: A Combination of Surgical Thrombectomy and Drug-Coated Balloon Ang... by Tatsuro Takei, Takashi Kajiya, Keisuke Yamamoto, Junichiro Takaoka, Yoshihiko Atsuchi, Nobuhiko Atsuchi

“…A 77-year-old man with a history of chronic kidney disease and coronary artery disease presented to our clinic with rest pain on his left leg. …”
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Oxidative stress and inflammation in hemodialysis: a comparison of patients with or without advanced nonalcoholic fatty liver disease (NAFLD) by Vanja Kalacun, Robert Ekart, Sebastjan Bevc, Pavel Skok, Radovan Hojs, Nina Vodošek Hojs

“…Nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease are global public health issues associated with high morbidity and mortality. …”
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In vivo antidiabetic and ex-vivo antioxidant activities of dichloromethane extract of Xerophyta spekei by Michael Musila Ndile, Wycliffe Arika Makori, Cromwell Mwiti Kibiti, Mathew Piero Ngugi

“…After 21 days, lipid profiles, kidney and liver function tests as well as ex vivo antioxidant assays were carried out. …”
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Non-Operative Management with Angioembolization of Grade IV and V Renal Injuries in a Hybrid Emergency Room System by So Ra Ahn, Sang Hyun Seo, Joo Hyun Lee, Chan Yong Park

“…The authors believe that the hybrid ER system with an in-house IR team could contribute to NOM and kidney preservation even in high-grade renal injuries.…”
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Design, synthesis, in vitro, and in silico studies of 4-fluorocinnamaldehyde based thiosemicarbazones as urease inhibitors by Muhammad Islam, Saeed Ullah, Ajmal Khan, Zahra Batool, Suraj N. Mali, Shailesh S. Gurav, Kholood A. Dahlous, Saikh Mohammad, Javid Hussain, Ahmed Al-Harrasi, Zahid Shafiq

“…Abstract Clinically significant problems such as kidney stones and stomach ulcers are linked to the activation of the urease enzyme. …”
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Nursing management for 5 patients undergoing Rituximab treatment for cryoglobulinemia-associated membranoproliferative glomerulonephritis (利妥昔单抗治疗5例冷球蛋白血症相关膜增生性肾小球肾炎患者的护理)... by LI Aijuan (李爱娟)

“…A single dose of rituximab was effective to reduce the level of cryoglobulin and stabilize kidney function of patients. Comprehensive nursing interventions included strictly fluid and volume management by daily weighing and intake and output volume recording, regulation of the medication care process, development of emergency risk plans for specialist treatment and emergency kit preparation, psychological care, peer education and creating an optimal sleep environment. …”
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Antiproliferative effect of hydroalcoholic brown propolis extract on tumor and non-tumor cells by I. Vendruscolo, G. H. Berton, M. T. Biffi, P. A. Bressiani, A. K. G. Oliveira, A. P. Berti, V. M. Concato-Lopes, W. R. Pavanelli, A. P. Simon, T. L. C. Oldoni, F. A. R. Santos, I. A. L. Dalmolin, M. H. G. Canteri, E. Düsman

“…The cytotoxicity test with normal kidney cells of Macaca mullata (LLC-MK2) and human lung tumor cells (A549) showed no statistical difference from the negative control. …”
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The link between hyperuricemia and diabetes: insights from a quantitative analysis of scientific literature by Lili Ma, Jing Wang, Li Ma, Xian Min Wang

“…The reference network from 1987 to September 30, 2024, identified 19 clusters highlighting key research areas in HUA and diabetes, such as metabolic syndrome, uropathology, chronic kidney disease (CKD), and CVD. Exploring pathological mechanisms and pharmacological interventions linked to diabetes concomitant with HUA has emerged as a focal point of research and a burgeoning trend within the field.ConclusionThis study is the first scientometric analysis to synthesize research trends on HUA and diabetes, revealing molecular mechanisms and treatment strategies and providing theoretical insights for future clinical use.…”
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Application and Evaluation of [Tc]-Labeled Peptide Nucleic Acid Targeting in Breast Cancer Imaging by Yaqun Jiang MD, Yongkang Gai PhD, Yu Long MD, Qingyao Liu PhD, Chunbao Liu MD, PhD, Yongxue Zhang MD, Xiaoli Lan MD, PhD

“…Single-photon emission computed tomography (SPECT) scan showed that radioactivity mainly accumulated in kidney. MCF-7 tumors, but not MDA-MB-231 tumors, were clearly visualized after [ 99m Tc]anti-PNA-155 injection. …”
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The Labial Adhesion in Postmenopausal Women: A Systematic Review by Nastaran Mahmoudnejad, Mohammad Hamidi Madani, Roozbeh Roohinezhad

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High glucose promotes macrophage switching to the M1 phenotype via the downregulation of STAT-3 mediated autophagy. by Yu Zhao, Yuteng Jiang, Fengmei Wang, Li Sun, Mengyuan Ding, Liyuan Zhang, Beibei Wu, Xiaoliang Zhang

“…<h4>Aim</h4>Imbalanced M1/M2 macrophage phenotype activation is a key point in diabetic kidney disease (DKD). Macrophages mainly exhibit the M1 phenotype, which contributes to inflammation and fibrosis in DKD. …”
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Neutralization by Insulin of the Hypertensive Effect of Dermcidin Isoform 2: An Environmentally Induced Diabetogenic and Hypertensive Protein by Rajeshwary Ghosh, Sarbashri Bank, Rabindra Bhattacharya, Nighat N. Khan, A. Kumar Sinha

“…Ingestion of acetyl salicylic acid (aspirin) (150 mg/70 kg body weight) decreased the systolic and diastolic pressures to 125 mm and 80 mm of Hg, respectively, with decrease of dermcidin level to 15 nM. Incubation of kidney cortex cells with 0.2 μM dermcidin-inhibited synthesis of (r)-cortexin, an antihypertensive protein, and the basal (r)-cortexin level was reduced from 33 nM to 15 nM. …”
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Renin-angiotensin-aldosterone system in ISIAH rats with stressinduced arterial hypertension by A. D. Dubinina, E. V. Antonov, L. A. Fedoseeva, E. N. Pivovarova, A. L. Markel, L. N. Ivanova

“…We estimated the serum levels of renin, the angiotensin-converting enzyme, angiotensin II and aldosterone by an enzymelinked immunosorbent assay, and mRNA expression of RAS genes in kidney, adrenals and brain tissues was measured by the real-time polymerase chain reaction. …”
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Effect of Gum Arabic (Acacia senegal) on Growth Performance, Carcass Quality and Health of Clarias gariepinus Juveniles by Augustine Eyiwunmi Falaye, Abel Abah, Shakiru Okanlawon Sule

“…At inclusion above GA5 the gill, liver, and kidney were affected histologically with no changes in the intestines of all treatments. …”
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Monacolin K as a Natural Alternative for Synthetic Statins by Julia Kozakiewicz, Aleksandra Okońska, Michał Ziemba, Kamil Kościelecki, Agnieszka Kalisz, Magdalena Krakowiak, Aleksandra Kaczmarek

“…In addition, there are also concerns about liver and/or kidney damage, headaches and/or dizziness, musculoskeletal symptoms and gastrointestinal disturbances in some people, especially when high doses of monacolin K are used. …”
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Risk Factors and Consequent Diseases of Atherosclerosis in a Population Treated in a Medical Office by Luis Ángel Felicó Riverón, Georgia Díaz-Perera Fernández, Yomeidis Felicó Riverón

“…Altered waist circumference has the highest risk associated with peripheral arterial disease; high blood pressure with cardiovascular disease and peripheral arterial disease; and diabetes and dyslipidemia with chronic kidney disease.<br /> <strong>Conclusions</strong>: the diagnosis of high blood pressure and cardiovascular diseases predominated. …”
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Hepatotoxic Effects of Gaseous Sulfur Dioxide (SO₂), Nitrogen Dioxide (NO₂), and Their Mixture on Sea Bass (Centropristis striata): Hematological, Biochemical and Genotoxic Studies... by N. Gandhi, Y. Rama Govinda Reddy and Ch. Vijaya

“…Simultaneously, alterations in serum biochemical parameters suggest potential impairments in liver and kidney functions, along with disturbances in lipid metabolism. …”
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Conducting genetic epidemiology research on hyperuricaemia and gout in an indigenous community in Guam - a feasibility study by Yvette C. Paulino, Frank Camacho, Tristan VC Paulino, Delores J. Lee, Lisa Linda Natividad, Elizabeth Matisoo-Smith, Tony R. Merriman, Anna L. Gosling

“…The prevalence of metabolic conditions from highest to lowest were obesity (55.6%), hyperuricaemia (36.0%), hypertension (27.8%), gout (23.0%), diabetes (14.9%), cardiovascular disease (8.4%), kidney disease (7.3%), and liver disease (3.4%). There was variation in the prevalence of metabolic conditions among the major ethnic groups in this study. …”
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