Loss of Kat2b impairs intraflagellar transport and the Hedgehog signaling pathway in primary cilia by Jae Hee Jun, Hwayeon Cha, Je Yeong Ko, Ho-Shik Kim, Kyung Hyun Yoo, Jong Hoon Park

“…In addition, Kat2b-knockout mice showed mild abnormalities and ciliary IFT defects in the kidneys. These results establish a link between acetylation regulated by Kat2b and its relevance to ciliary assembly and function.…”
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TNM-Like Classification: A New Proposed Method for Heart Failure Staging by Francesco Fedele, Maria Chiara Gatto, Alessandra D’Ambrosi, Massimo Mancone

“…With an eye on the TNM staging used in oncology, we drawn up a classification that will consider the different involvement of organs such as lungs, kidneys, and liver in addition to psychological pattern and quality of life in HF patients. …”
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The Nephroprotective Effect of Andrographis Paniculata Ethanol Extract Chitosan Nanoparticles on Vero cells by Wahyu Kurniawan Dhadhang, Nabilah, Nuryanti, Novrial Dody, Aries Nurulita Nunuk

“…Nephroprotective agents are substances that protect the kidneys from nephrotoxicity. Some nephroprotective agents are derived from medicinal plants. …”
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Clinical and morphological features of salmonellosis in cows and calves affected by heat stress by L. I. Drozdova, E. N. Shilova, I. A. Shkuratova, M. V. Ryaposova

“…Some pathological processestypical for sepsiswere foundin other parenchymalorgans (kidneys, heart). The nature of pathological changes in dicates that there is as epticprocess that spreads both hematogenically and lymphogenically, and the structure of granulomas most likely indicates that such apathogen as Salmonelacholeraesuis circulates in cattle.…”
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Case of acute drug-induced hepatitis after halothane anesthesia by I. Yu. Pirogova, Ye. V. Berestova, O. Yu. Bastrikov, Ye. B. Kovaleva, T. P. Petukhova, M. V. Guseva, I. A. Gubina, I. V. Rezepin, S. P. Sinitsyn

“…Biotransformation of volatile anesthetics can result in production of toxic metabolites and metabolic by-products, resulting in damage of the liver and kidneys. Disorders of liver function can be of two types: early – transient elevation of transaminase activity and late – liver necrosis. …”
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Disturbance of Inorganic Phosphate Metabolism in Diabetes Mellitus: Its Relevance to the Pathogenesis of Diabetic Retinopathy by H. Vorum, J. Ditzel

“…First, the homeostatic function of the kidneys is suboptimal in diabetes, because elevated blood glucose concentrations depolarize the brush border membrane for Pi reabsorption and lead to lack of intracellular phosphate and hyperphosphaturia. …”
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Delirium Accompanied by Cholinergic Deficiency and Organ Failure in a 73-Year-Old Critically Ill Patient: Physostigmine as a Therapeutic Option by Benedikt Zujalovic, Eberhard Barth

“…Acetylcholine is a major transmitter of the parasympathetic nervous system influencing several organs (e.g., heart and kidneys) and the inflammatory response too. This perception might explain that delirium is not an individual symptom, but rather a part of a symptom complex with various disorders of the whole organism. …”
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Profil Lipid dan Kejadian Hipertensi pada Pria Perokok Berat by Yonrizal Nurdin

“… The cigarette will lead to peripheral vasoconstriction of the blood vessels and vessels in the kidneys, leading to an increase in blood pressure. …”
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Frequency of branching pattern variation of the renal artery in a subset of Karachi population: A Study on Multi-Detector Computed Tomography by Maria Mohiuddin, Rosheena Nabeel Khan, Syeda Bushra Ahmed, Mubina Lakhani, Amatul Sughra, Nuzhat Hassan

“…A total of 250 participants (500 kidneys) aged 21 to 60 years and serum creatinine of ≤ 1.3 mg /dl were included in the study. …”
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A Case of an Elderly Woman Who Developed Corneal Perforation in the Clinical Course of Myeloperoxidase Positive Antineutrophil Cytoplasmic Antibody-Associated Vasculitis by Shuhei Kobayashi, Makoto Harada, Aiko Yamada, Yasuhiro Iesato, Koji Hashimoto, Yuji Kamijo

“…Although AAV leads to systemic organ injury, such as of the lungs, kidneys, nerves, and skin, patients with AAV sometimes develop ocular lesions. …”
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Murine model evaluation of biochemical and tissue-damage induced by Bothrops asper (Nauyaca) snake venom by Dr. Carlos Gallardo-Casas Ángel Gallardo-Casas, María Teresa Valadez-Omaña, Emmanuel Correa Solís, María del Carmen Castillo-Hernández, Rocio Ortiz-Butron

“…Subsequently, the mice were administered the LD25 value of the venom (or saline solution for control), and 24 hours after the injection, LDH, AST, and ALT enzymes were measured in the blood, and the liver and kidneys were collected from each animal. Results: Results: Animals treated with poison (LD25 of 1 mg of protein/kg) had greater activity of AST, ALT and LDH enzymes, structural damage in the cortex and renal medulla, as well as in the liver after 24 hours of administration in the experimental group Conclusion: B. asper venom causes an increase in LDH and transaminase enzymes, as well as renal and hepatic histopathological alterations. …”
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Adverse Health Effects of the Long-Term Simultaneous Exposure to Arsenic and Particulate Matter in a Murine Model by Cesar Rivas-Santiago, Maria Gallegos-Bañuelos, Irving Trejo-Ramos, Nancy Solís-Torres, Raúl Quintana-Belmares, Noé Macías-Segura, Héctor Gutiérrez-Bañuelos, Lorena Troncoso-Vazquez, Bruno Rivas-Santiago, Irma Gonzalez-Curiel

“…After 7, 14, and 28 days of exposure, the animals were euthanized and serum, lungs, kidneys, and hearts were collected. Analysis performed showed high levels of lung inflammation in all experimental groups, with an additive effect in the coexposed group. …”
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Sympathetic Nervous Regulation in Patients with Cirrhosis: Pathogenesis of Fluid Retention and Formation of Ascites by Jens H Henriksen, Helmer Ring-Larsen, Niels Juel Christensen

“…In patients with cirrhosis, the kidneys have been identified as an important source of noradrenaline ‘spillover’ into plasma, which indicates enhanced sympathetic nervous activity in these organs. …”
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Acute toxicity test and lethal dose (LD50) from a combination of sambiloto extracts (Andrographis paniculate) and catfish oil (Pangasius micronema Blkr.) in mice by Rinanda Al Rissa Rizki Hera, Meitasari Annisa Diyan, Sasongko Heru

“…The extract was administered for 14 days, and symptoms of toxicity were observed, including the number of animals that died, body weight, and the weight of the liver, kidneys, and heart. The data was then tested using the Thompson-Weil method and statistical tests using the oneway ANOVA test and continued with the Tukey post hoc test. …”
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QUALITATIVE RISK ASSESSMENT OF AVIAN INFLUENZA VIRUS TRANSMISSION THROUGH INCUBATION EGGS by A. S. Oganesyan, A. V. Varkentin, N. Ye. Baskakova, A. K. Karaulov

“…Evidence of actual vertical transmission of highly pathogenic avian influenza virus is limited, however, it is recognized that the infection manifests by systemic lesions in the organs (bursa, thymus, spleen, heart, pancreas, kidneys, brain, trachea, lungs, adrenals and skeletal muscles). …”
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The Role of Sulfatides in Liver Health and Disease by Lin Chen, Montserrat Elizalde, Gloria Alvarez-Sola

“…Sulfatides or 3-O-sulfogalactosylceramide are negatively charged sulfated glycosphingolipids abundant in the brain and kidneys and play crucial roles in nerve impulse conduction and urinary pH regulation. …”
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Intravascular Large B-Cell Lymphoma Mimicking Temporal Arteritis by Ifeyinwa Emmanuela Obiorah, Metin Ozdemirli

“…On autopsy, there was disseminated intravascular lymphoma involving predominantly vessels within the heart, kidneys, liver, stomach, lungs, adrenal glands, small intestine, bladder, thyroid, and brain. …”
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Principles of portal hypertension treatment at patients with liver cirrhosis by Ye. A. Fedosina, M. V. Mayevskaya, V. T. Ivashkin

“…As the major part of these states peripheral vasodilation, prescription of vasoconstrictors (first of all — terlipressin) is pathogenically justified and results in arrest of acute bleedings from esophageal VV, and in functional recovery of kidneys at renal failure.…”
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Safety Considerations When Dry Needling the Multifidi in the Thoracolumbar Region: A Cadaveric Study by Christi L. Williams, Christian R. Falyar, Ryan C. McConnell, Stacey Lindsley

“…While studies have examined the safety considerations in the upper lumbar spine related to the kidneys and lungs, none have investigated the possibility of entering the spinal canal in this region…”
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Large Pyoderma Gangrenosum-Like Ulcers: A Rare Presentation of Granulomatosis with Polyangiitis by Basheer Tashtoush, Roya Memarpour, Yasmin Johnston, Jose Ramirez

“…Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis (WG), is a rare systemic vasculitis that classically manifests as necrotizing granulomas of the upper and lower respiratory tract, kidneys, and blood vessels; however, it may affect any organ system, including the skin. …”
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