Association Between Depressive Symptoms and Comorbidities Among Elderly Diabetic Individuals in China by Luyao Qiao, Xin Pan, Tianpei Li, Shouqin Yi, Zhenyu Tang

“…With the exception for dyslipidemia (OR = 1.195, 95% CI: 0.969, 1.475), individuals with hypertension, heart disease, stroke, kidney disease, memory‐related disease, or arthritis/rheumatism were prone to develop depressive status in the fully adjusted model. …”
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Pulmonary cavernous hemangioma: a case report by Wei Li, Xingxing Zheng, Hongzhe Tian, Yu Xi, Yuhao Liu

“…Abstract Background Cavernous hemangiomas can occur in various internal organs like the liver, kidney, bladder, and skin, or even in subcutaneous tissues. …”
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Migration, Distribution, and Safety Evaluation of Specific Phenotypic and Functional Mouse Spleen-Derived Invariant Natural Killer T2 Cells after Adoptive Infusion by Dongzhi Chen, Wenbin Xu, Jingfang Teng, Huifang Liu, Yuanyuan Wang, Yan Wang, Shujie Cheng, Ming Meng

“…After dissecting the mice, it was found that there were no significant abnormalities in the relevant immune organs, brain, heart, kidney, lung, and other organs. Intraperitoneal injection of α-GalCer results in a large number of iNKT2 cells, mainly secreting anti-inflammatory cytokine IL-4, from the spleen of mice. …”
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Effect of Intensive Blood Pressure Control on Cardiovascular Remodeling in Hypertensive Patients with Nephrosclerosis by Otelio Randall, John Kwagyan, Tamrat Retta, Kenneth Jamerson, Velvie Pogue, Keith Norris, Muluemebet Ketete, Shichen Xu, Tom Greene, Xuelei Wang, Lawrence Agodoa

“…We studied 1094 nondiabetics with nephrosclerosis in the African American Study of Kidney Disease and Hypertension. Subjects were randomly assigned to usual MAP goal (102–107 mmHg) or a lower MAP goal (≤92 mmHg) and randomized to beta-blocker, angiotensin converting enzyme inhibitor, or calcium channel blocker. …”
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P-cadherin-dependent adhesions are required for single lumen formation and HGF-mediated cell protrusions during epithelial morphogenesis by Sydnie K. Tran, Jessanne Y. Lichtenberg, Corinne E. Leonard, Jessica R. Williamson, Hazel R. Sterling, Grace K. Panek, Amanda H. Pearson, Santiago Lopez, Christopher A. Lemmon, Daniel E. Conway, Priscilla Y. Hwang

“…Here, we investigated the role of CDH3 on successful lumen formation and cell protrusions, using three-dimensional cultures of Madin-Darby canine kidney (MDCK) and CDH3 knockout cell lines. We show that depletion of CDH3 leads to perturbations of hollow lumen formation associated with defects in cell protrusions and tubulogenesis, mediated by Rho/ROCK pathway. …”
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SGLT2i and GLP-1RA in Cardiometabolic and Renal Diseases: From Glycemic Control to Adipose Tissue Inflammation and Senescence by Luis D'Marco, Valery Morillo, José Luis Gorriz, María K. Suarez, Manuel Nava, Ángel Ortega, Heliana Parra, Nelson Villasmil, Joselyn Rojas-Quintero, Valmore Bermúdez

“…Moreover, other frequent comorbidities in long-standing diabetic patients are chronic complications such as diabetic kidney disease, whose progression can be slowed by SGLT2i and/or GLP-1RA. …”
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No Detection of SARS-CoV-2 RNA on Urethral Swab in Patients with Positive Nasopharyngeal Swab by Lorenzo Spirito, Biagio Pinchera, Angela Patrì, Mario Delfino, Ciro Imbimbo, Paola Salvatore, Ivan Gentile, Gabriella Fabbrocini

“…Viral RNA is found in the lung, intestine, testicle, kidney, etc., which suggests the virus can be transmitted also via routes besides respiratory droplets. …”
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The Value of a Panel of Autoantibodies for Predicting the Activity of Lupus Nephritis at Time of Renal Biopsy by Gabriella Moroni, Silvana Quaglini, Antonella Radice, Barbara Trezzi, Francesca Raffiotta, Piergiorgio Messa, Renato Alberto Sinico

“…We tested a panel of autoantibodies and complement at the time of kidney biopsy and after treatment. Anti-dsDNA, anti-nucleosome, anti-ribosome P, and anti-C1q antibodies and C3/C4 were measured in 107 patients with LN at the time of renal biopsy and after 6–12 months and were correlated with clinical/histological parameters. …”
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Case Report: Rare cardiovascular characteristics of tuberous sclerosis complex with novel TSC2 variant by Zhiqin Du, Xiao Ma, Xiao Ma, Xiao Ma, Jianhua Li, Fang Yang, Yangfan Guo, Yangfan Guo

“…Cardiovascular characteristics included a history of heart valve disease, a bicuspid aortic valve, and severe aortic regurgitation. multi-system characteristics of TSC were also presented, affecting skin, brain, lung, kidney, and bone. She underwent aortic valve replacement but experienced postoperative complications, including significant pleural and pericardial effusions requiring drainage and subsequent thoracic duct ligation.ConclusionThis case expands the clinical spectrum of TSC-associated cardiovascular abnormalities, highlighting the rare association of BAV with this disorder. …”
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The challenges of using Escherichia coli as a host in recombinant insulin production by Muhammad Taher

“… Diabetes mellitus is a metabolic disease characterised by elevation of blood glucose level which leads to serious damage to the blood vessels, eyes, heart, kidney, and nerves affecting about 830 million people worldwide. …”
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Examining the relationship between incidence and mortality for commonly diagnosed cancers in the USA: an observational study using population-based SEER database by H Gilbert Welch, Adewole S Adamson, Vishal R Patel

“…The moderate-correlation tercile (r: 0.75 to 0.58) included cancers of the colon, bladder, kidney and uterus. There was little or no relationship between incidence and mortality for cancers in the low-correlation tercile (r: 0.33 to −0.10): melanoma, prostate, breast and thyroid. …”
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AKI Epidemiology and Outcomes: A Retrospective Cohort Study from the Prenephrology Era by K. Asmus, S. Erfurt, O. Ritter, S. Patschan, D. Patschan

“…Background. Acute kidney injury substantially worsens the prognosis of hospitalized patients. …”
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Comparative genomics of Leptospira santarosai reveals genomic adaptations in bovine genital strains by Maria Isabel Nogueira Di Azevedo, Frederico Kremer, Camila Ezepha, João Pedro Gomes Greco, Isadora Cosenza Vieira da Silva, Pascale Bourhy, Walter Lilenbaum

“…Important aspects of the interactions between the host and the pathogen during chronic leptospirosis have been well described in the kidney, but little is known about the genital infection mechanisms. …”
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Antilipotoxicity Activity of Osmanthus fragrans and Chrysanthemum morifolium Flower Extracts in Hepatocytes and Renal Glomerular Mesangial Cells by Po-Jung Tsai, Mei-Ling Chang, Ching-Mei Hsin, Chung-Chieh Chuang, Lu-Te Chuang, Wen-Huey Wu

“…The excess influx of free fatty acids (FFAs) into nonadipose tissues, such as those of liver and kidney, induces lipotoxicity leading to hepatic steatosis and renal dysfunction. …”
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Novel yeast Pichia kudriavzevii alleviates aflatoxins induced toxicopathology in broiler chickens through immunomodulation and antioxidant enhancement by Ashiq Ali, Aisha Khatoon, Muhammad Kashif Saleemi, Rao Zahid Abbas, Bilal Murtaza, Kaynaat Akbar, Qaisar Tanveer, Sami Ullah Khan Bahadur, Hissah Abdulrahman Alodaini, Mai Ahmad Alghamdi

“…Additionally, gross and microscopic lesions on liver and kidney were examined. The study highlights Pichia kudriavzevii as a promising agent for mitigating aflatoxin-induced toxicity in broiler chicks by improving antioxidant and immunomodulatory status, normalizing biomarkers, and reversing pathological alterations through multifaceted protective mechanisms.…”
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Effects of Red Clover Isoflavones on Growth Performance, Immune Function, and Cecal Microflora of Mice by Rongrong Guo, Xuqin Song, Xiaodie Li, Cheng Zeng, Ying Chen, Chunjie Li, Jian Yang, Deyuan Ou

“…The organ indexes and blood biochemical indexes of the mice in each RCI group were in the normal range, indicating that RCIs do not damage liver or kidney function. RCI supplementation increased serum immunity and altered the microbial community structure in the cecum of the mice. …”
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Case Report: Nephrotic syndrome as the primary manifestation of Alport syndrome in a Chinese pediatric patient by Yue Song, Yifei Li, Liqun Lu, Changqiang Yang, Jing Lu

“…BackgroundAlport syndrome (AS) is a genetically heterogeneous disorder resulting from variants in genes coding for the alpha-3/4/5 chains of Collagen IV, leading to defective basement membranes in the kidney, cochlea, and eye. The clinical manifestations of AS vary in patients. …”
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Successful Outcome of a Corticodependent Henoch-Schönlein Purpura Adult with Rituximab by Taylor Pindi Sala, Jean-Marie Michot, Renaud Snanoudj, Marion Dollat, Emmanuel Estève, Bernadette Marie, Yacine Taoufik, Jean-François Delfraissy, Thierry Lazure, Olivier Lambotte

“…We report the case of a 49-year-old woman with medical history of kidney transplantation for segmental glomerular hyalinosis. …”
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Comparison of creatinine‐based methods for estimating glomerular filtration rate in patients with heart failure by Anna Jonsson, Ida Viklund, Andreas Jonsson, Fredrik Valham, Ellinor Bergdahl, Krister Lindmark, Helena Norberg

“…Methods and results One hundred forty‐six HF patients (mean age 68 ± 13 years, mean left ventricular ejection fraction 45% ± 15) within a single‐centre hospital that underwent 51Cr‐EDTA clearance between 2010 and 2018 were included in this retrospective study. eGFR was estimated by means of Cockcroft–Gault ideal and actual weight, the Modification of Diet in Renal Disease Study (MDRD), simplified MDRD with isotope dilution mass spectroscopy traceable calibration, the Chronic Kidney Disease Epidemiology Collaboration, revised Lund–Malmö, full age spectrum, and the Berlin Initiative Study 1. …”
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Direct Medical Expenditures Associated with Eye Complications among Adults with Diabetes in the United States by Abdulkarim M. Meraya, Monira Alwhaibi, Moteb A. Khobrani, Hafiz A. Makeen, Saad S. Alqahtani, David Banji

“…After controlling for sex, age, race, poverty level, insurance coverage, prescription coverage, perceived physical and mental health, the number of chronic physical and mental conditions, marital status, education, the region of residence, smoking status, exercise, and chronic kidney disease (CKD), there was no difference in the out-of-pocket spending burden between adults with and those without ECs. …”
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