Diabetic microangiopathies: mechanisms of development, approaches to the therapy by Birukova E.V, Shinkin M.V.

“…Among patients with type 1 diabetes mellitus, one-third have serious kidney complications, characterized by an increase in urinary albumin excretion and a decrease in renal function, up to hemodialysis.…”
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Biochemical and histopathological profiling of Wistar rat treated with Brassica napus as a supplementary feed by Kazi Md. Mahmudul Hasan, Nasrin Tamanna, Md. Anwarul Haque

“…The aim of this animal study is to determine the effects of high erucic acid containing rapeseed oil (Brassica napus L.) varieties on liver, kidney and heart muscles in Wistar rats. Male Wistar rats were divided into three groups where each group containing four rats. …”
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Clinical Practice Guidelines of Traditional Chinese Medicine Rehabilitation for Incomplete Paraplegia by Working Group of Clinical Practice Guidelines of Traditional Chinese Medicine Rehabilitation for Incomplete Paraplegia

“…We sort out the treatment, evidence level, recommended opinions and recommended prescriptions of different syndrome types of incomplete paraplegia, such as blood stasis syndrome, Qi deficiency and blood stasis syndrome, spleen and stomach weakness syndrome, liver and kidney deficiency syndrome, Qi and blood deficiency syndrome and so on. …”
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Clinicoradiological Manifestations of Melioidosis with Pulmonary Involvement in a Tertiary Hospital Setup by P Prem Ananth, R Anand, R Prathipa, S Raghul Raj, N Nagarajan

“…Diabetes mellitus was the most common comorbid followed by chronic kidney disease. Radiologically, the right upper lobes (46.6%) are more commonly involved followed by the left upper lobe (23.3%). …”
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Severe Bioprosthetic Mitral Valve Stenosis and Heart Failure in a Young Woman with Systemic Lupus Erythematosus by Siddharth Wartak, Isaac Akkad, Adnan Sadiq, Gregory Crooke, Manfred Moskovits, Robert Frankel, Gerald Hollander, Jacob Shani

“…She was treated for heart failure but in view of her persistent symptoms and low EF was considered for heart and kidney transplant. This was a challenge in view of her history of lupus. …”
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Inhibition of early EHDV2-Ibaraki infection steps in bovine cells by endosome alkalinization or ikarugamycin, but not by blockage of individual endocytic pathways by Maya Malka, Inbar Czaczkes, Shlomi Kashkash, Shirel Shachar, Eran Bacharach, Marcelo Ehrlich

“…The endosome alkalinizing agent ammonium chloride blocked EHDV2-Ibaraki infection of Madin-Darby Bovine Kidney (MDBK) cells with dependence on its time of addition, suggesting the criticality of endosomal pH for the completion of early stages of infection. …”
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Elevation of preoperative cystatin C as an early predictor of contrast-induced nephropathy in patients receiving percutaneous coronary intervention by Guoqiang Gu, Ningning Yu, Yaqing Zhou, Wei Cui

“…Serum creatinine (SCr) is a commonly used biomarker of renal function, but an elevation in SCr lags behind the onset of kidney injury and is not viable for early detection of CIN after PCI. …”
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Mitochondrial Dysfunction and Diabetic Nephropathy: Nontraditional Therapeutic Opportunities by Ping Na Zhang, Meng Qi Zhou, Jing Guo, Hui Juan Zheng, Jingyi Tang, Chao Zhang, Yu Ning Liu, Wei Jing Liu, Yao Xian Wang

“…Growing evidence shows that persistent mitochondrial dysfunction contributes to the progression of renal diseases, including DN, as it alters mitochondrial homeostasis and, in turn, affects normal kidney function. Pharmacological regulation of mitochondrial networking is a promising therapeutic strategy for preventing and restoring renal function in DN. …”
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Euodiae Fructus: a review of botany, application, processing, phytochemistry, quality control, pharmacology, and toxicology by Yule Hao, Jiawen Qi, Xinggui Huang, Chenhao Liu, Yi Liu

“…It also exhibits diverse toxicological properties and poses specific toxic risks to the liver, heart, and kidney. Nonetheless, research is scarce regarding the toxicology of EF, especially on its cardiotoxicity and nephrotoxicity. …”
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A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements by Kazuhiko Higashioka, Kenji Yoshida, Kensuke Oryoji, Kazuo Kamada, Shinichi Mizuki, Hiroshi Tsukamoto, Eisuke Yokota, Koichi Akashi

“…He was suspected as having SLE or malignant lymphoma but diagnosed as having IgG4-RD by the elevated serum IgG4 level and histological findings from kidney and lymph node. We report a case of IgG4-RD with multiple ten-organ involvement that was successfully treated with prednisolone therapy.…”
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The Efficiency of Chitosan Against Tert Butylhydroquinone (TBHQ)-Induced Neurobehavioral Changes and Toxicity Effects in Male Rats by Shahad Alahmadi, Mohammed Mufadhe Alanazi, Fawaz Alasmari, Wedad Saeed Al-Qahtani, Gadah Albasher

“…Background: We investigated chitosan’s protective effects against tertiary butylhydroquinone (TBHQ)-induced toxicity in adult male rats, focusing on cognitive functions and oxidative stress in the brain, liver, and kidneys. …”
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Toxicopathological Effects of the Venom of Echis ocellatus on Experimentally Envenomated Swiss Albino Rats by P. O. Yusuf, G. Ada, D. B. Nuhu, S. Dahiru, P. M. Ameh, M. Mamman, M. U. Kawu, M. Bisallah, S. J. Enam

“…These findings suggest the venom of Echis ocellatus induces significant hematotoxicity, with pathological involvement of the heart, liver, kidneys, and spleen. …”
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Comparative Analysis of the Full-Length Genome Sequence of a Clinical Isolate of Human Parainfluenza Virus 4B by John A. Lednicky, Thomas B. Waltzek, Micah D. Halpern, Sara B. Hamilton

“…In this paper, hPIV-4 was detected in primary rhesus monkey kidney (PRMK) cells that had been inoculated with nasopharyngeal swab material obtained from a child with a mild upper respiratory tract illness. …”
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Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes by Mahnoor Mahnoor, Syeda Aina Ali, Saira Nasir, Moiz Azmat, Hafiz Muhammad Umer Farooqi

“…<b>Background</b>: Emphysematous pyelonephritis (EPN) is an infectious disease of the renal system caused by gas-producing microorganisms harboring the kidneys. Patients with diabetes mellitus (DM), an endocrine disease with hyperglycemia, are particularly susceptible to the EPN as their immune system is compromised in fighting against infections. …”
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Circulating CTRP1 Levels Are Increased and Associated with the STOD in Essential Hypertension in Chinese Patients by Zhengjia Su, Shuya Tian, Wei Liang

“…In conclusion, CTRP1 levels are increased and associated with the STOD (heart and kidney) in essential hypertension, which can be regarded as a novel biomarker in the prediction of prognosis for patients with essential hypertension.…”
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Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center Experience by Pedro W. Baron, Ramzi Ben-Youssef, Okechukwu N. Ojogho, Arputharaj Kore, D. Duane Baldwin

“…Recipients of laparoscopically procured kidneys have been reported to have delayed graft function, a slower creatinine nadir, and potential significant complications. …”
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A Retrospective Study: Quick Scoring of Symptoms to Estimate the Risk of Cardiac Arrest in the Emergency Department by Yaoke Xu, Hua Zhang, Zongxuan Zhao, Kaifeng Wen, Ci Tian, Qiangrong Zhai, Yi Bai, Shu Li, Hongxia Ge, Xiaodan Li, Qidi Zhou, Qingbian Ma

“…Gender (p<0.001), age (p<0.001), history of heart failure (p=0.006), chronic kidney disease (p=0.011), and hyperlipidemia (p=0.004) were other factors contributing to our model. …”
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In Vivo Hypoglycaemic Effect and Inhibitory Mechanism of the Branch Bark Extract of the Mulberry on STZ-Induced Diabetic Mice by Hua-Yu Liu, Meng Fang, Yu-Qing Zhang

“…Mulberry BBE was orally administered to STZ-induced diabetic mice for three weeks, and it improved the weight gain and ameliorated the swelling of liver and kidney in diabetic mice. Obviously, mulberry BBE not only can reduce the abnormally elevated levels of serum insulin and ameliorate insulin resistance induced by STZ, but also it regulates dyslipidemia in diabetic mice. …”
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Recent advances in 3D-printing-based organ-on-a-chip by Xinkun Wu, Wenwan Shi, Xiaojiang Liu, Zhongze Gu

“…In this review, recent advances in 3D-printing-based OOC are systematically summarized based on materials used for direct or indirect 3D printing of OOC, 3D printing techniques for the construction of OOC, and applications of 3D-printing-based OOC in models of the heart, blood vessels, intestines, liver, and kidney. Moreover, the paper outlines prospective vistas and hurdles within the field, intended to catalyze innovative use of 3D printing methodologies to propel OOC advancements.…”
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Uroprotective and Hepatoprotective Potential of Anagallis arvensis against the Experimental Animal Model by Ushna Shabbir, Irfan Anjum, Muhammad Naveed Mushtaq, Muhammad Nasir Hayat Malik, Sana Ismail, Joham Javed, Saeeda Noreen, Ayesha Pervaiz, Anika Tariq, Misbah Wazir, Zeenat Islam, Muhammad Majid, Sehrish Mansha, Zaka Ur Rehman

“…Anagallis arvensis (A. arvensis) belonging to the family Primulaceae is traditionally used for liver and kidney diseases. The aim of the study was to evaluate the uroprotective and hepatoprotective potentials of A. arvensis in cyclophosphamide-induced interstitial cystitis and paracetamol-induced hepatotoxicity rat model, respectively. …”
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