Sedoanalgesia Strategies and their Potential Benefits in the Intensive Care Unit: Narrative Review of the Literature by Arango-Martínez, Alejandro, Penagos-Sanchez, Sebastian, Restrepo-Arismendy, Simón, Arias-Correa, Ruber Hernando

“…Results: Lower rates of delirium and ICU stay were found for dexmedetomidine, while for midazolam and propofol a possible anti-inflammatory effect was found, and for ketamine a potential benefit in the hemodynamic profile was suggested. …”
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Ovariohysterectomy in Cat as An Alternative Handling of Fetus Mummification Cases by Cindy Ercha Aulia Putri, Erma Safitri, Winda Syafitri

“…Anesthesia during the ovariohysterectomy procedure involved the use of atropine sulfate, xylazine, and ketamine. Despite the extensive medical intervention, the cat, Bimbim, succumbed to its critical condition during the surgery. …”
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From Serendipity to Precision: Integrating AI, Multi-Omics, and Human-Specific Models for Personalized Neuropsychiatric Care by Masaru Tanaka

“…<b>Background/Objectives</b>: The dual forces of structured inquiry and serendipitous discovery have long shaped neuropsychiatric research, with groundbreaking treatments such as lithium and ketamine resulting from unexpected discoveries. However, relying on chance is becoming increasingly insufficient to address the rising prevalence of mental health disorders like depression and schizophrenia, which necessitate precise, innovative approaches. …”
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A Case of Schizophrenia in a Young Male Adult with no History of Substance Abuse: Impact of Clinical Pharmacists’ Interventions on Patient Outcome by Mercy N. A. Opare-Addo, Josephine Mensah, Grace Owusu Aboagye

“…Medications administered to the patient while on admission included IV diazepam, IM haloperidol, IV Ketamine, IM flupentixol, olanzapine tablets, and trihexyphenidyl tablets. …”
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Pharmacological effects of purple basil extract on ısolated mouse bladder functions and underlying molecular mechanisms by Naciye YAKTUBAY DÖNDAŞ, Beyza Nur ARSLAN

“…Mice were sacrificed under ketamine-xylazine anesthesia, bladder tissues were isolated. …”
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Research on treatment-related aspects of depression from India in the preceding decade (2014–2023): An updated systematic review by Alankrit Jaiswal, S Umesh, Nishant Goyal

“…Conclusion: More research is needed to understand the effectiveness and potential negative effects of depression treatments in India. Studies on ketamine have been inconclusive, and existing research on pharmacological agents is limited. …”
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The Evaluation of Endotracheal Intubation Effect on Blood Flow Stability Parameters in Baghdad and Gazzi AL-Harriri Hospitals by Azhar A. Mhaibes

“…Dexamethasone (0.11 mg/kg), Metoclopramide (0.14mg/kg), Ranitidine (0.71mg/kg) & Ketamine (0.5 mg/kg) as premedication. At the induction of anesthesia, patients were administrated (2-3 mg/kg) Propofol as a hypnotic drug and succinylcholine 1 mg/kg as a muscle relaxant. …”
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Elimination of Large Bladder Stone-Obstructing Pelvic Canal in African Spurred Tortoise (Centrochelys sulcata) with Per-Cloacal Bladder Stone Removal Method without Utilizing an En... by Nofan Rickyawan, drh., M.Sc., Vivi Oktavia, Dodik Prasetyo

“…This procedure begins by anesthetizing the sulcata tortoise using ketamine and medetomidine combination, followed by fragmentation and extraction of the bladder stones from the pelvic canal through the cloaca. …”
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Investigation of the effects of Afyonkarahisar Region hot springs water on blood calcium and some hormon levels in experimentally-created osteoporosis in rats by Bülent Elitok, Tolgahan Saygin, Yavuz Ulusoy, Bahadir Kilinç

“…Ovaries were removed from all animals under anesthesia with ketamine (200 mg/kg) and xylazine (10 mg/kg), after which they were divided into two groups: control (10 animals) and experimental (15 animals). …”
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Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy by Tigist Bacha, Segni Kejela, Scott A. Hagen

“…The most common procedural sedation used was the combination of ketamine and propofol in 60.6%. The mean pain score during the procedure was 0.28/10, which was significantly lower than the pre-procedural pain score (p-value < 0.001). …”
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The Effect of Eight Weeks of High Intensity Interval Training (HIIT) on the Content of Mitochondrial Fission and Fusion Proteins in the Left Ventricle of Old Rats by Mahdi Marezloo, Neda Aghaei Bahmanbeglou, Hamed Alizadeh pahlavani, Habib Asgharpour

“…Following a 48-hour period post the most recent training session, the rats were subjected to anaesthesia through the administration of Ketamine and Xylazine.  Subsequently, the left ventricle of the heart was excised, and the various parameters were measured utilizing the western blot laboratory technique. …”
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Efficacy of an Intrathecal Multidrug Infusion for Pain Control in Older Adults and in End-Stage Malignancies: A Report of Three Cases by Sadegh Abdolmohammadi, Pierre-Olivier Hétu, Andrée Néron, Gilbert Blaise

“…It was connected to an external infusion pump with a mixture of bupivacaine 1 mg/mL, naloxone 0.02 ng/mL, ketamine 100 μg/mL, morphine 0.01 mg/mL and clonidine 0.75 μg/mL. …”
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Comparative Effects of Verapamil, Nicardipine, and Nitroglycerin on Myocardial Ischemia/Reperfusion Injury by Hitoshi Yui, Uno Imaizumi, Hisashi Beppu, Mitsuhiro Ito, Munetaka Furuya, Hirofumi Arisaka, Kazu-Ichi Yoshida

“…Rabbits received regional ischemia by 30 min of left anterior descending coronary artery occlusion followed by 3 hours of reperfusion under ketamine and xylazine anesthesia. The animals were randomly assigned to the following 4 treatment groups: a control group, a verapamil group, a nicardipine group, and a nitroglycerin group. …”
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Model of Liver Fibrosis Induction by Thioacetamide in Rats for Regenerative Therapy Studies by Nathaly Enciso, José Amiel, Fredy Fabián-Domínguez, Jhon Pando, Nancy Rojas, Carlos Cisneros-Huamaní, Ernesto Nava, Javier Enciso

“…Groups G-I and G-II were sacrificed 7 days after the last dose of ASC, and G-III was sacrificed 8 weeks after the last ASC infusion, all with xylazine/ketamine (40 mg/kg). The protocol used in this work established a model of advanced hepatic fibrosis as corroborated by METAVIR tests of the histological lesions; by the high levels of the markers α-SMA, CD68, and collagen type I; by functional alterations due to elevated markers of the hepatic lesions; and by alterations of the leukocytes, lymphocytes, and platelets. …”
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Dimethyl fumarate effects on paraquat-induced hepatotoxicity in mice via anti-oxidative, anti-inflammatory, and anti-apoptotic activities by Maryam Kavianinia, Hadi Kalantar, Maryam Salehcheh, Layasadat Khorsandi, Saeedeh Shariati, Shokooh Mohtadi, Mohammad Javad Khodayar

“…On the 8th day, mice were euthanized with ketamine/xylazine, and serum factors, oxidative stress markers, apoptosis index, and inflammatory markers were measured. …”
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Part 3. Clinical Practice Guideline for Airway Management and Emergency Thoracotomy for Trauma Patients from the Korean Society of Traumatology by Chan Yong Park, O Hyun Kim, Sung Wook Chang, Kang Kook Choi, Kyung Hak Lee, Seong Yup Kim, Maru Kim, Gil Jae Lee, Korean Society of Traumatology (KST) Clinical Research Group

“…What should be used as an induction drug for airway intubation? Ketamine or etomidate can be used as a sedative induction drug when RSI is being performed in a trauma patient (2B). …”
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Effect of a multimodal analgesia strategy on remifentanil daily consumption in mechanically ventilated adult ICU patients: study protocol for a randomised, placebo-controlled, doub... by Thibault Mura, Jean-Yves Lefrant, Remy Widehem, Camille Nicolet, Violaine Delannoy, Laurie Barthelemi, Ian Soulairol, Claire Roger

“…In the interventional group, patients will receive a standardised multimodal analgesia, initially receiving nefopam and tramadol, implementing with ketamine if patients remain painful, and then implementing with remifentanil with escalating doses in case of insufficient analgesia. …”
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Comparison between Rocuronium and Atracurium Effect on Blood Pressure during General Anaesthesia in Baghdad Hospital by Adel Amen Hama, Noor Faris Hoobi, Sara Emad Majeed

“…Anesthesia was induced with using I.V. propofol drug (1.5-2.5 mg/kg), ketamine drug (0.5 mg/kg) or (2-3 mg/kg) propofol drug.  …”
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The effect of anesthesia on postoperative cognitive dysfunction in adults undergoing cataract surgery: a systematic review by Elaheh Foroughi, Etrusca Brogi, Francesco Forfori, Seyyed Taghi Hashemi

“…General anesthesia may cause POCD approximately twofold than local anesthesia. Ketamine, Midazolam, or Dexmedetomidine seemed to reduce postoperative cognitive complications compared to the control group‌‌. …”
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Systemic Inflammatory Effects of Traumatic Brain Injury, Femur Fracture, and Shock: An Experimental Murine Polytrauma Model by C. Probst, M. J. Mirzayan, P. Mommsen, C. Zeckey, T. Tegeder, L. Geerken, M. Maegele, A. Samii, M. van Griensven

“…Methods. 45 male C57BL/6J mice (mean weight 27 g) were anesthetized with ketamine/xylazine. Animals were subjected to a weight drop closed traumatic brain injury (WD-TBI), a femoral fracture and hemorrhagic shock (FX-SH). …”
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