Historical Pathways for Opioid Addiction, Withdrawal with Traditional and Alternative Treatment Options with Ketamine, Cannabinoids, and Noribogaine: A Narrative Review by Amber N. Edinoff, Natalie W. Wu, Catherine A. Nix, Bryce Bonin, Rama Mouhaffel, Stephen Vining, William Gibson, Elyse M. Cornett, Kevin S. Murnane, Adam M. Kaye, Alan D. Kaye

“…Beyond its use as an anesthetic, ketamine has been shown to have many applications in several medical specialties. …”
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Clinical trials since 2020 of rapid anti-suicidal ideation effects of ketamine and its enantiomers: a systematic review by Sumra Sajid, J. John Mann, Michael F. Grunebaum

“…Multiple and single doses of IN ketamine/S-ketamine and single doses of IV ketamine produced less consistent anti-SI results. …”
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Trends in research on novel antidepressant treatments by Agnieszka Zelek-Molik, Ewa Litwa

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Comparison of anesthetic effects of xylazine combined with alfaxalone or ketamine and maintained with isoflurane in captive Formosan Reeve’s Muntjac (Muntiacus reevesi micrurus) by Li-Jen Chang, Zixuan Wang, Chen-Yeh Lien, Amanda H.C. Wen

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Morphine in Combination with Ketamine Improves Cervical Cancer Pain and Suppresses Immune Function via the JAK3/STAT5 Pathway by Yurong Jiang, Tong Li, Yi Qian, Xiaoming Zuo, Jinmei Liu

“…Background. The role of ketamine as an adjuvant for morphine in the treatment of cancer pain and immune functions has been confirmed. …”
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The Use of Electronic Consent (eConsent) Within the Ketamine for Long-Lasting Pain Relief After Surgery (KALPAS) Multicenter Trial by Doan LV, Burr J, Perez R, Martinez H, Cuevas R, Watt K, Wang J

“…It has streamlined the process of consenting patients and has been shown to benefit the research study team and participants.eConsent in the Ketamine Analgesia for Long-Lasting Pain Relief After Surgery (Kalpas) Study: The KALPAS study is a multicenter, double-blind, randomized controlled study investigating the effectiveness of ketamine in reducing chronic post-mastectomy pain in women undergoing mastectomy for oncologic indication. …”
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Acute Effects of Ketamine Infusion on Postoperative Mood Scores in Patients Undergoing Dilation and Curettage: A Randomized Double-Blind Controlled Study by Raham Hasan Mostafa, Ahmed Mohamed Khamis, Ashraf Nabil Saleh, Yehia Mamdouh Hassan Mekki, Mohamed Mohamed Kamal, Ismail Mohammed Ibrahim, Mohamed Abdulmohsen Abdulnaiem Ismaiel

“…In the last decade, it has been suggested that low dose of ketamine is a fast-acting antidepressant. Purpose. …”
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Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions by Jai Ahuja, Luba Leontieva

“…This case report examines the unexpected increase in suicidal ideation following ketamine infusion therapy in a 75-year-old female with a history of treatment-resistant depression. …”
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Low-Dose Ketamine Infusion for Perioperative Pain Management in Patients Undergoing Laparoscopic Gastric Bypass: A Prospective Randomized Controlled Trial by Mitchell T. Seman, Shawn H. Malan, Matthew R. Buras, Richard J. Butterfield, Kristi L. Harold, James A. Madura, David M. Rosenfeld, Andrew W. Gorlin

“…The ketamine group received a 0.3 mg/kg ideal body weight ketamine bolus after induction followed by a 0.2 mg/kg/hr ketamine infusion continued into the postop setting for up to 24 hours. …”
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Intraoperative low-dose ketamine infusion for postoperative pain relief in laparoscopic surgeries – A randomised, double blind controlled clinical trial by Sujil Sudersan, Ramyavel Thangavelu, Sivakumar Segaran

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Interaction of physostigmine with three injectable anaesthetics in a young chick model by H. M. S. Garmavy, F. K. Mohammad

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Strategies to innovate emergency care of status epilepticus by Jaideep Kapur

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Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome by Kyle N. Kaneko, Pablo Read, John M. Eaton, Yoshie Umemura, Justin L. Hoskin

“…Here, we present a case of refractory focal status epilepticus in a patient with SMART syndrome who was treated with ketamine, which resolved seizures without the need for intubation.…”
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Ketamine Use in Hysterosalpingography (the Jimah Procedure): A Follow-Up of Bilateral Tubal Evaluation of 27 Infertile  Women  at a Teaching Hospital, Ghana by Bashiru Babatunde Jimah, Anthony Baffour Appiah, Benjamin Dabo Sarkodie, Dorothea Anim

“…We performed repeated HSG workup under IV ketamine (20–40 mg/mL) sedation for 27 infertile women at the Cape Coast Teaching Hospital. …”
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Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain Injury by Bradley A. Dengler, Oliver Karam, Colleen A. Barthol, Aaron Chance, Laura E. Snider, Clare M. Mundy, Michael T. Bounajem, William C. Johnson, Moustafa M. Maita, Paola M. Mendez-Gomez, Ali Seifi, Shaheryar Hafeez

“…We evaluated the effects of ketamine boluses on both ICP and cerebral perfusion pressure (CPP) in patients with severe TBI and refractory ICP. …”
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Comparison of intravenous dexmedetomidine versus ketamine–dexmedetomidine combination on spinal block characteristics in patients undergoing lower limb orthopaedic surgery – A randomised clinical trial by Annapureddy Sai Krishna, Jyotsna Agarwal, Samiksha Khanuja, Sandeep Kumar, Adam Khan, Khairat Mohammad Butt

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Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression by Kasper Recourt, Joop Van Gerven, Joop Van Gerven, Nadieh Drenth, Jeroen van der Grond, Kantaro Nishigori, Nic J. Van Der Wee, Gabriël E. Jacobs, Gabriël E. Jacobs

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Ketamine Infusion as an Adjunct to Opioid Analgesia in Pediatric Patients with High-Risk Neuroblastoma Undergoing Treatment with Dinutuximab: Adverse Effects and Safety in a Non-ICU Setting by Streby KA, Tobias JD, McPhaden E, Downie S, Stanek J, Roth C, Patel PO

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Perioperative Change of High‐Sensitive Cardiac Troponin I Concentration in Cats According to Three Different Anaesthesia Protocols by Tarik Safak, Oznur Yılmaz‐Koç, Ebru Karakaya‐Bilen

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Comparative Evaluation of Regain of Consciousness in Dexmedetomidine–Propofol versus Ketamine–Propofol in the Pediatric Cardiac Catheterization Procedure under Sedation using BIS Monitoring: A Randomized Prospective Study by Priya Banga, Sunder L. Negi, Banashree Mandal, Parag Barwad, Kulbhushan Saini, Krishna P. Gourav

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