Systematic Review into Diagnostics for Post-Kala-Azar Dermal Leishmaniasis (PKDL) by Emily R. Adams, Inge Versteeg, Mariska M. G. Leeflang

“…Identification of post-kala-azar dermal leishmaniasis (PKDL) is important due to the long and toxic treatment and the fact that PKDL patients may serve as a reservoir for visceral leishmaniasis (VL). …”
Get full text

Application of kDNA Minicircle PCR-RFLP to Characterize Leishmania donovani Clinical Isolates Obtained from Post-Kala-Azar Dermal Leishmaniasis in Eastern Nepal by Ojesh Pokhrel, Keshav Rai, Narayan Raj Bhattarai, Suman Rijal, Arpana Rijal, Basudha Khanal

“…Post-kala-azar dermal leishmaniasis (PKDL) is a skin manifestation of visceral leishmaniasis (VL) which develops after apparent cure in some patients. …”
Get full text

Post-kala-azar dermal leishmaniasis (PKDL) drug efficacy study landscape: A systematic scoping review of clinical trials and observational studies to assess the feasibility of establishing an individual participant-level data (IPD) platform. by Sauman Singh-Phulgenda, Rishikesh Kumar, Prabin Dahal, Abdalla Munir, Sumayyah Rashan, Rutuja Chhajed, Caitlin Naylor, Brittany J Maguire, Niyamat Ali Siddiqui, Eli Harriss, Manju Rahi, Fabiana Alves, Shyam Sundar, Kasia Stepniewska, Ahmed Musa, Philippe J Guerin, Krishna Pandey

“…<h4>Background</h4>Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis which can occur after successful treatment of visceral leishmaniasis (VL) and is a public health problem in VL endemic areas. …”
Get full text

Climate Change and Environmental Influence on Prevalence of Visceral Leishmaniasis in West Pokot County, Kenya by Bulle Abdullahi, Joshua Mutiso, Fredrick Maloba, John Macharia, Mark Riongoita, Michael Gicheru

“…Kala-azar is a parasitic disease caused by Leishmania species transmitted by sand fly. …”
Get full text

Mathematical Model Analysis and Simulation of Visceral Leishmaniasis, Kashgar, Xinjiang, 2004–2016 by Yateng Song, Tailei Zhang, Hui Li, Kai Wang, Xiaobo Lu

“…Visceral leishmaniasis (VL), known as kala-azar, is a serious parasitic disease. After malaria, VL is the second largest parasitic killer. …”
Get full text

Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review by Pashupati Pokharel, Rakesh Ghimire, Pratik Lamichhane

“…Visceral leishmaniasis, also known as kala-azar is one of the most commonly neglected tropical diseases affecting a large number of rural and resource-limited people in South Asia, Africa, and South America. …”
Get full text

Mixed Cutaneous Infection Caused by Leishmania and Dermatophytes: A Rare Coincidence or Immunological Fact by Amresh Kumar Singh, Ankur Kumar, Jayesh Pandey, Vivek Gaur, Pratima Tripathi, Indra Prasad Adhikari

“…A diagnosis of PKDL with tinea was made based on the history of kala-azar and on the skin slit smear for amastigote forms, rK39 test, and KOH mount. …”
Get full text

The leishmaniases in Kenya: A scoping review. by Grace Grifferty, Hugh Shirley, Katherine O'Brien, Jason L Hirsch, Adrienne M Orriols, Kiira Lani Amechi, Joshua Lo, Neeharika Chanda, Sarra El Hamzaoui, Jorja Kahn, Samantha V Yap, Kyleigh E Watson, Christina Curran, Amina Atef AbdelAlim, Neeloy Bose, Alissa Link Cilfone, Richard Wamai

“…Endemic in over 100 countries, the four types of leishmaniasis-visceral leishmaniasis (VL) (known as kala-azar), cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), and post-kala-azar dermal leishmaniasis (PKDL)-put 1.6 billion people at risk. …”
Get full text

Strategies to Overcome Antileishmanial Drugs Unresponsiveness by Shyam Sundar, Anup Singh, Om Prakash Singh

“…In the current review, we highlight various steps which could be implemented to halt the increasing unresponsiveness of drugs such as monitoring of therapy in the form of rational dosing and duration of treatment, understanding the mechanism of action of the drugs and drug resistance, identification of markers of resistance, distribution of drugs free of cost, evolution of effective combination therapy and immunotherapy, and proper management of HIV/VL coinfection and post-kala-azar dermal leishmaniasis (PKDL). Strong support from governmental agencies and local communities in the form of education and orientation programmes for feasibility of implementing these strategies and affordability within the context of their health systems is needed in controlling and preventing leishmaniasis.…”
Get full text

Phase 4 Pharmacovigilance Trial of Paromomycin Injection for the Treatment of Visceral Leishmaniasis in India by Prabhat K. Sinha, T. K. Jha, Chandreshwar P. Thakur, Devendra Nath, Supriyo Mukherjee, Amrendra Kumar Aditya, Shyam Sundar

Get full text

Development of a Novel Rapid Immunodiagnostic Kit Based on Flagellar 40 kDa Antigen Epitope for the Detection of Typhoid Fever in Indian Patients by Rahul Mitra, Surya Bhan, Gopal Nath, Narender Kumar, Ziledar Ali

“…The immunodiagnostic kit on analysis gave a positive result with clinically diagnosed typhoid positive patient serum and negative results were obtained with the sera of clinically diagnosed malaria, abscess of Staphylococcus aureus and Visceral leishmaniasis (Kala-azar) patients.…”
Get full text

Seroprevalence of Asymptomatic Leishmania donovani among Laborers and Associated Risk Factors in Agricultural Camps of West Armachiho District, Northwest Ethiopia: A Cross-Sectiona... by Animen Ayehu, Yibeltal Aschale, Wossenseged Lemma, Animut Alebel, Ligabaw Worku, Ayalew Jejaw, Abebe Genetu Bayih

“…Visceral leishmaniasis (VL, also called kala-azar) is a public health problem in Ethiopia, especially in sesame and sorghum growing areas. …”
Get full text