In vitro evaluation of anthelmintic activity of biocompatibile carbon quantum dot nanocomposite against egg and larval stages of equine strongyles by Armin Fakheri, Bijan Esmaeilnejad, Hamid Akbari, Rahim Molaei

“…Conclusions Given the potential for resistance to Ivermectin, seeking suitable alternatives is essential. …”
Get full text

Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta. by Jennifer McIntyre, Alison Morrison, Kirsty Maitland, Duncan Berger, Daniel R G Price, Sam Dougan, Dionysis Grigoriadis, Alan Tracey, Nancy Holroyd, Katie Bull, Hannah Rose Vineer, Mike J Glover, Eric R Morgan, Alasdair J Nisbet, Tom N McNeilly, Yvonne Bartley, Neil Sargison, Dave Bartley, Matt Berriman, James A Cotton, Eileen Devaney, Roz Laing, Stephen R Doyle

“…Genome-wide analyses of drug resistance, combining evidence from three distinct experiments, identified selection around known candidate genes for benzimidazole, levamisole and ivermectin resistance, as well as novel regions associated with ivermectin and moxidectin resistance. …”
Get full text

Bullous Scabies in an Immunocompromised Host by James R. Wester, Lesley E Jackson, Kathryn Mokgosi, Tomer Barak, Mahmoud Abu Hazeem

“…The patient was initiated on topical permethrin. Oral ivermectin was not available in country and was obtained from overseas shipment, delaying treatment initiation. …”
Get full text

Burden of scabies in a Ghanaian penitentiary. by Yaw Ampem Amoako, Michael Ntiamoah Oppong, Dennis Odai Laryea, Gloria Kyem, Solomon Gyabaah, Abigail Agbanyo, Bernadette Agbavor, Nana Konama Kotey, Irene Dzathor, Felicia Owusu-Antwi, Kingsley Asiedu, Richard Odame Phillips, Ymkje Stienstra

“…Therefore, we aimed to assess the burden of scabies and ascertain if prevalence was high enough to warrant mass drug administration (MDA) with ivermectin in a medium security prison in central Ghana.…”
Get full text

Veterinary Drug Prescribing Practices at Selected District Veterinary Clinics of Rift Valley Areas of Ethiopia by Monenus Etefa, Ashenafi Feyisa Beyi, Dinka Ayana, Tariku Jibat Beyene, Takele Beyene Tufa

“…Among the total drugs, oxytetracycline, ivermectin, penstrep, sulfa drugs, and albendazole were the most leading prescribed drugs with a frequency of 43.0%, 17.6%, 10.2%, 6.5%, and 1.3%, respectively. …”
Get full text

Antifilarial Activity of the Methanolic Extract of Indigofera tinctoria (Fabaceae) on Bovine Parasites (Onchocerca ochengi) by Enock Enock Rakwa, Benoît Bargui Koubala, Bertrand Ndou Mando, Mathieu Djongra, Francis Nveikoueing, Dieudonné Ndjonka

“…The control of onchocerciasis relies much on the use of the chemical drug ivermectin, which is only effective against microfilariae and has led to drug resistance. …”
Get full text

Crusted Demodicosis in an Immunocompetent Pediatric Patient by Guillermo Antonio Guerrero-González, Maira Elizabeth Herz-Ruelas, Minerva Gómez-Flores, Jorge Ocampo-Candiani

“…Oral ivermectin was repeated every week and oral erythromycin plus topical metronidazole cream was added. …”
Get full text

Fluralaner systemic treatment of chickens results in mortality in Triatoma gerstaeckeri, vector of the agent of Chagas disease by Cassandra Durden, Yuexun Tian, Koyle Knape, Cory Klemashevich, Keri N. Norman, John B. Carey, Sarah A. Hamer, Gabriel L. Hamer

“…The insecticide products tested included: Safe-Guard® Aquasol (fenbendazole), Ivomec® Pour-On (ivermectin) and Bravecto® (fluralaner). Triatoma gerstaeckeri nymphs were allowed to feed on insecticide-live birds at 0, 3, 7, 14, 28 and 56 days post-treatment. …”
Get full text

Onchocerciasis is not a major cause of blindness in two endemic villages in Sierra Leone by Ibrahim Kargbo-Labour, Victoria Redwood-Sawyerr, Abdulai Conteh, Doris Harding, Mohamed S. Bah, Patricia Houck, Sugandh Juneja, Achille Kabore, Darin Evans, Angela M. Weaver, Yaobi Zhang

“…Despite 17 rounds of annual ivermectin treatment since 2005, a report circulated by a local politician indicated an increase in cases of suspected onchocerciasis-related vision impairment in two villages (Mangobo and Petifu) in Tonkolili district. …”
Get full text

Severe subcutaneous infection with Clostridium septicum in a herd of native Icelandic horses by Charlotta Oddsdóttir, Ólöf G. Sigurðardóttir, Vala Friðriksdóttir, Vilhjálmur Svansson, Birkir Þór Bragason, Sigríður Björnsdóttir

“…Such infections have not been reported in Iceland, although ivermectin products formulated for subcutaneous injection have been widely used for more than 30 years. …”
Get full text

On-farm molecular epidemiology and therapeutic insights into multidrug-resistant Staphylococcus aureus isolated from bubaline mastitis by Muhammad Ijaz, Muhammad Umar Javed, Arslan Ahmed, Hamza Rasheed, Farwa Anwar, Syed Faizan Ali Shah, Jawad Sabir

“…The resistant antibiotics were combined with non- antibiotics (NSAIDs and ivermectin) using well diffusion method and checkerboard assay to evaluate resistance modulation. …”
Get full text

Current Evidence on the Use of Antifilarial Agents in the Management of bancroftian Filariasis by Sumadhya Deepika Fernando, Chaturaka Rodrigo, Senaka Rajapakse

“…Diethylcarbamazine (DEC) remains the prime antifilarial agent with a well-established microfilaricidal and some macrofilaricidal effects. Ivermectin (IVM) is highly microfilaricidal but minimally macrofilaricidal. …”
Get full text

Therapeutic effectiveness of three commercial anthelmintics against strongylids in buffalo calves (Bubalus bubalis) by David Uzcátegui, Víctor Gutiérrez, María Rodríguez, Andrea González, Alfredo Sánchez

“…Furthermore, levamisole was most effective against strongylids. In the case of ivermectin, the FEC reduction percentage was less than 90% during the trial, resulting in a low-CI 95% of -7.2%, showing possible anthelmintic resistance. …”
Get full text

Insecticidal Activity of Some Traditionally Used Ethiopian Medicinal Plants against Sheep Ked Melophagus ovinus by Negero Gemeda, Walelegn Mokonnen, Hirut Lemma, Ashenif Tadele, Kelbessa Urga, Getachew Addis, Asfaw Debella, Mesaye Getachew, Frehiwot Teka, Kidist Yirsaw, Kissi Mudie, Solomon Gebre

“…Twelve medicinal plants and a commercially used drug Ivermectin were examined for insecticidal activity against Melophagus ovinus sheep ked at different time intervals using in vitro adult immersion test. …”
Get full text

Dermatitis due to Mixed Demodex and Sarcoptes Mites in Dogs by B. Sudhakara Reddy, K. Nalini Kumari, S. Sivajothi, R. Venkatasivakumar

“…Both dogs were treated with daily oral ivermectin at 100 to 400 μg/kg body weight as incremental doses, external application of amitraz and supportive treatments with topical antimicrobial shampoo. …”
Get full text

Rosacea-like skin reaction under treatment with dupilumab for atopic dermatitis by C. Grote, F. Zirkenbach, J. N. Wagner, M. Augustin

“…At first, dupilumab was continued alongside doxycycline, metronidazole gel and ivermectin cream.Results Following a worsening of her skin condition, dupilumab was discontinued. …”
Get full text

Anti-SARS-CoV-2 Biotherapeutics and Chemotherapeutics: An Insight into Product Specifications and Marketing Dynamics by Vijay Kotra, Dinakar Mallem, Anil Kumar Kanuri, Mahesh Reddy Burra, Shaik Nyamathullah, Looi Shu Ying, Khairul Anwar Husain, Ravi Varala, Madhadevi Sudhakar, Khang Wen Goh, Toong Hai Sam, Long Chiau Ming

“…There are several chemotherapeutics that have been studied for the treatment of COVID-19, including Paxlovid (Nirmatrelvir & Ritonavir) fixed dose combination, nirmatrelvir and ritonavir fixed dose combination, Remdesivir (Vekulary/Covifor) fixed dose combination, chloroquine and hydroxychloroquine, molnupiravir, favipiravir, Infliximab (Remsima®) fixed dose combination tocilizumab (Actimera), casirivimab+imdevimab (Ronapreve) fixed dose combination, ivermectin, methylprednisole. These drugs have been repurposed for use in COVID-19 due to their antiviral properties and ability to reduce inflammation. …”
Get full text

Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout by Murtaza Mazhar, Ijlal Akbar Ali, Nelson Iván Agudelo Higuita

“…The patient was treated with a three-week course of ivermectin with complete resolution of signs, symptoms, peripheral eosinophilia, and the positive IgG serology. …”
Get full text

Knowledge, Attitude, and Practice of Community towards an Onchocerciasis Elimination Program from South West Ethiopia by Haile Worku, Misganaw Mola, Bizuwork Derebew Alemu, Sebwedin Surur Jemal, Aklilu Ayiza, Samuel Getachew, Nitin Mahendra Chauhan, Sunil Tulshiram Hajare, Suresh Chandra Singh, Mohammed Kuddus, Vijay J. Upadhye

“…The communities attitude towards community directed therapy (CDT) using Ivermectin is positive (68.5%). According to 56% of the community, offering incentives for community drug distributors (CDD) has the potential to make the elimination campaign more successful. …”
Get full text

Macrofilaricidal Activity, Acute and Biochemical Effects of Three Lichen Species Found on Mount Cameroon by Thierry Roland Kang, Jerome Nyhalah Dinga, Ayuk Elizabeth Orock, Elvis Monya, Moses Njutain Ngemenya

“…Onchocerciasis is a parasitic infection affecting a relatively small population globally but has very devastating pathological outcomes. Ivermectin and recently moxidectin are the only drugs approved for clinical management of the disease, both of which have several limitations. …”
Get full text