An Adrenocortical Carcinoma Associated with Non-Islet Cell Tumor Hypoglycemia and Aberrant ACTH Production by M. D. S. A. Dilrukshi, A. W. Wickramarachchi, D. D. K. Abeyaratne, Brian Shine, Bahram Jafar-Mohammadi, N. P. Somasundaram

“…He was diagnosed with a diffusely disseminated adrenocortical carcinoma with immunohistochemistry of tumor cells showing focal ACTH immunostain positivity. Conclusion. Non-islet cell tumor hypoglycemia and ACTH-dependent Cushing’s syndrome are extremely rare presentations of an ACC, and co-occurrence of these entities in a single patient is never reported in the literature.…”
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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies by Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Ziliang Ao, Mark Meloche, C. Bruce Verchere, Lieping Chen, Dawei Ou, Alice Mui, Garth L. Warnock

“…Type 1 diabetes (T1D) is a chronic autoimmune disease and characterized by absolute insulin deficiency. β-cell replacement by islet cell transplantation has been established as a feasible treatment option for T1D. …”
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IL-6 Promotes Islet β-Cell Dysfunction in Rat Collagen-Induced Arthritis by Huan Jin, Yaogui Ning, Haotong Zhou, Youlian Wang

“…Fasting insulin (FIns) and the expressions of IL-6 were detected by ELISA. Islet caspase-3 was examined by immunohistochemistry. …”
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Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation by Hiroki Shima, Akiko Inagaki, Takehiro Imura, Youhei Yamagata, Kimiko Watanabe, Kazuhiko Igarashi, Masafumi Goto, Kazutaka Murayama

“…The clostridial collagenases, H and G, play key roles in pancreatic islet isolation. Collagenases digest the peptide bond between Yaa and the subsequent Gly in Gly-Xaa-Yaa repeats. …”
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Enhanced dynorphin expression and secretion in pancreatic beta-cells under hyperglycemic conditions by Miranda Movahed, Ruy A. Louzada, Manuel Blandino-Rosano

Subjects: “…Islet…”
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Combined Microencapsulated Islet Transplantation and Revascularization of Aortorenal Bypass in a Diabetic Nephropathy Rat Model by Yunqiang He, Ziqiang Xu, Hongxing Fu, Bin Chen, Silu Wang, Bicheng Chen, Mengtao Zhou, Yong Cai

“…The levels of urine protein and the expression of MCP-1 in graft vessels were decreased after islet transplantation. The injury of glomerular basement membrane and podocytes was significantly ameliorated. …”
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Molecular Structure, Membrane Interactions, and Toxicity of the Islet Amyloid Polypeptide in Type 2 Diabetes Mellitus by Lucie Caillon, Anais R. F. Hoffmann, Alexandra Botz, Lucie Khemtemourian

“…Human islet amyloid polypeptide (hIAPP) is the major component of the amyloid deposits found in the pancreatic islets of patients with type 2 diabetes mellitus (T2DM). …”
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Reversal of Early Diabetic Nephropathy by Islet Transplantation under the Kidney Capsule in a Rat Model by Yunqiang He, Ziqiang Xu, Mingshi Zhou, Minmin Wu, Xuehai Chen, Silu Wang, Kaiyan Qiu, Yong Cai, Hongxing Fu, Bicheng Chen, Mengtao Zhou

“…Diabetic nephropathy (DN) is a common microvascular complication of diabetes mellitus, and insulin therapy has many side effects in the treatment of DN. Islet transplantation has emerged as a promising therapy for diabetic patients. …”
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Human Islet Amyloid Polypeptide Fibril Binding to Catalase: A Transmission Electron Microscopy and Microplate Study by Nathaniel G. N. Milton, J. Robin Harris

“…The diabetes-associated human islet amyloid polypeptide (IAPP) is a 37-amino-acid peptide that forms fibrils in vitro and in vivo. …”
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Genetically Engineered Islets and Alternative Sources of Insulin-Producing Cells for Treating Autoimmune Diabetes: Quo Vadis? by Feng-Cheng Chou, Shing-Hwa Huang, Huey-Kang Sytwu

“…Islet transplantation is a promising therapy for patients with type 1 diabetes that can provide moment-to-moment metabolic control of glucose and allow them to achieve insulin independence. …”
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Recent Insight in Islet Amyloid Polypeptide Morphology, Structure, Membrane Interaction, and Toxicity in Type 2 Diabetes by Lucie Khemtemourian, Ehud Gazit, Andrew Miranker

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Pravastatin Improves Glucose Regulation and Biocompatibility of Agarose Encapsulated Porcine Islets following Transplantation into Pancreatectomized Dogs by Lawrence S. Gazda, Horatiu V. Vinerean, Melissa A. Laramore, Richard D. Hall, Joseph W. Carraway, Barry H. Smith

“…The encapsulation of porcine islets is an attractive methodology for the treatment of Type I diabetes. …”
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Generalizability of machine learning models for diabetes detection a study with nordic islet transplant and PIMA datasets by Dinesh Chellappan, Harikumar Rajaguru

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Changes in Intestinal Microbiota Are Associated with Islet Function in a Mouse Model of Dietary Vitamin A Deficiency by Yunting Zhou, Junming Zhou, Yumin Zhang, Jun Tang, Bo Sun, Wei Xu, Xiaohang Wang, Yang Chen, Zilin Sun

“…We found intestinal microbiota effect islet function via controlling intestinal inflammatory phenotype in VAD diet-fed mice. …”
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Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells by Nadine E. Rekittke, Meidjie Ang, Divya Rawat, Rahul Khatri, Thomas Linn

“…Type 1 diabetes is an autoimmune disease resulting in the permanent destruction of pancreatic islets. Islet transplantation to portal vein provides an approach to compensate for loss of insulin producing cells. …”
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Naringin prevents heart mitochondria dysfunction during diabetic cardiomyopathy in rats by Ilya Zavodnik, Tatsiana A. Kavalenia, Siarhei N. Kirko, Elena B. Belonovskaya, Irina A. Kuzmitskaya, Yulia V. Eroshenko, Elena A. Lapshina, Vyacheslav U. Buko

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Corrigendum to “TERT and Akt Are Involved in the Par-4-Dependent Apoptosis of Islet β Cells in Type 2 Diabetes” by Chen Liu, Wu QiNan, Lei XiaoTian, Yang MengLiu, Gan XiaGuang, Leng WeiLing, Liang ZiWen, Zhang Ling, Yang GangYi, Chen Bing

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Detection of Islet Cell Immune Reactivity with Low Glycemic Index Foods: Is This a Concern for Type 1 Diabetes? by Datis Kharrazian, Martha Herbert, Aristo Vojdani

“…We measured the reactivity of either monoclonal or polyclonal affinity-purified antibodies to insulin, insulin receptor alpha, insulin receptor beta, zinc transporter 8 (ZnT8), tyrosine phosphatase-based islet antigen 2 (IA2), and glutamic acid decarboxylase (GAD) 65 and 67 against 204 dietary proteins that are commonly consumed. …”
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Antioxidant Effects of Eugenol on Oxidative Stress Induced by Hydrogen Peroxide in Islets of Langerhans Isolated from Male Mouse by Ali Akbar Oroojan, Narges Chenani, Marzieh An’aam

“…The antioxidant system in islets of Langerhans is weak, which can lead to diabetes. …”
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Activation of GPR119 Stimulates Human β-Cell Replication and Neogenesis in Humanized Mice with Functional Human Islets by Ansarullah, Colette Free, Jenica Christopherson, Quanhai Chen, Jie Gao, Chengyang Liu, Ali Naji, Alex Rabinovitch, Zhiguang Guo

“…Using humanized mice with functional human islets, we investigated whether activating GPR119 by PSN632408, a small molecular agonist, can stimulate human β-cell regeneration in vivo. …”
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