The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases by Sasmitra Kandasamy, Vengadesh Letchumanan, Kar Wai Hong, Kah-Ooi Chua, Nurul Syakima Ab Mutalib, Alvin Lai Oon Ng, Long Chiau Ming, Hui Xuan Lim, Sivakumar Thurairajasingam, Jodi Woan-Fei Law, Loh Teng-Hern Tan

“… Dysbiosis is a prominent factor in numerous inflammatory conditions, with Ruminococcus gnavus, a prevalent gut microbe, implicated in inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), eczema, metabolic disorders, and rheumatic diseases. …”
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Linking gut microbiota to aging process: a new target for anti-aging by Maoyang Lu, Zhao Wang

“…Gut microbiota is linked to lots of diseases, including human metabolic diseases such as obesity, type 2 diabetes (T2D), irritable bowel syndrome, and cardiovascular disease (CVD). …”
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Infective Endocarditis Presented as a Right Atrium Mass in a Patient with Ulcerative Colitis by Ali Asghar Moeinipour, Hamid Hoseinikhah, Mohamad Ali Kiani, Naser Tayyebi Meibodi, Mohammad Hassan Aelami, Ali Reza Sepehri Shamloo, Shahram Amini

“…Involvement of the heart is infrequently seen in irritable bowel syndrome (IBD). We present a case of severe acute infective endocarditis diagnosed as ulcerative colitis in further workup.…”
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Duodenal Peptic Ulcer Perforation in the Puerperium Case Report Series by Elizabeth Stiles, Andre Robinson, Erin Fitzgerald, Marie Fleury, Andrew Rubenstein

“…We present two case reports of primigravida, advanced maternal age females with history of irritable bowel syndrome and nonsteroidal anti-inflammatory drug (NSAID) use found to have perforated duodenal ulcers after Cesarean section. …”
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New Rome-IV criteria of the functional dyspepsia (review) by A. A. Sheptulin, A. A. Kurbatova

“…Frequent combination of PDS and EPS both with each other, with such symptoms as nausea and belching and some other diseases as gastroesophageal reflux disease and irritable bowel syndrome was demonstrated. It is, still, recommended to make the diagnosis of FD, being guided both by compliance of patients symptoms to Rome criteria and the absence of alarm symptoms. …”
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Up-to-date approaches to treatment of the functional constipation at children by V. F. Privorotsky, N. Ye. Luppova

“…According to ICD-10, in the respective section, irritable bowel syndrome (IBS) and functional constipation itself are traditionally distinguished. …”
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Visceral pain and sensitisation in women with dysmenorrhea: a narrative review by Zeltia Naia, Sergio Patiño-Núñez, Olalla Bello

“…Women with dysmenorrhea have more possibilities to develop gastrointestinal pathologies like irritable bowel syndrome.…”
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Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy by Patrick Schoeters, Karl De Pooter

“…The patient’s stool transit was markedly improved (type 4 or type 5 according to the Bristol Stool Chart compared to type 7 before the treatment), positively affecting the patient’s quality of life (mean score of 2.1 on the Irritable Bowel Syndrome Quality of Life questionnaire compared to 3.9 before the treatment). …”
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Testing for Gluten-Related Disorders in Clinical Practice: The Role of Serology in Managing the Spectrum of Gluten Sensitivity by David Armstrong, Andrew C Don-Wauchope, Elena F Verdu

“…However, our understanding of the pathogenesis and spectrum of gluten sensitivity has improved, and gluten-sensitive irritable bowel syndrome patients are increasingly being recognized. …”
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Fecal Calprotectin Use in Inflammatory Bowel Disease and Beyond: A Mini-Review by Bashaar Alibrahim, Mohammed I Aljasser, Baljinder Salh

“…This has been used to distinguish patients exhibiting symptoms of irritable bowel syndrome from patients with inflammatory bowel disease, with a measure of success greater than with currently used techniques. …”
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Treatment compliance of patients with gastro-intestinal diseases by O. P. Alekseyeva, L. N. Kasimova, Ye. Ye. Goryacheva

“…Overall 151 patients (57 - with irritable bowel syndrome, 57 - with gastroesophageal reflux disease and 37 - with peptic ulcer of the stomach and duodenum) were investigated by structured interview method applying «the basic questionnaire for clinical and epidemiologic ethnocultural studies». …”
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Faecal microbiota transplantation for patients with diabetes type 1 and severe gastrointestinal neuropathy (FADIGAS): a randomised, double-blinded, placebo-controlled trialResearch... by Katrine Lundby Høyer, Simon Mark Dahl Baunwall, Ditte Smed Kornum, Mette Winther Klinge, Asbjørn Mohr Drewes, Knud Bonnet Yderstræde, Louise Bruun Thingholm, Martin Steen Mortensen, Susan Mikkelsen, Christian Erikstrup, Christian Lodberg Hvas, Klaus Krogh

“…The Irritable Bowel Syndrome Impact Scale score improved from 108 (101–123) to 140 (124–161) with FMT and 77 (53–129) to 92 (54–142) with placebo (p = 0.02). …”
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Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability by Lijun Du, John J. Kim, Jinhua Shen, Ning Dai

“…Abnormalities in intestinal barrier function expressed by increased intestinal permeability have long been observed in various gastrointestinal disorders such as Crohn’s disease (CD), ulcerative colitis (UC), celiac disease, and irritable bowel syndrome (IBS). Imbalance of metabolizing junction proteins and mucosal inflammation contributes to intestinal hyperpermeability. …”
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Inflammation, impaired motor function and visceral hypersensitivity: the main mechanisms of functional disorders of the gastrointestinal tract (materials of the Expert Council and... by V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, T. L. Lapina, V. I. Simanenkov, K. A. Sokolov

“…The pathogenesis of the most common functional diseases of the gastrointestinal tract — functional dyspepsia (FD) and irritable bowel syndrome (IBS) is multifactorial and includes motor disorders of various parts of the gastrointestinal tract, visceral hypersensitivity, changes in the intestinal microbiome, impairment of the permeability of the protective barrier, low-grade inflammation of the gastrointestinal mucosa, etc. …”
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Clinical Onset of Celiac Disease after an Episode of Campylobacter jejuni Enteritis by EF Verdu, M Mauro, J Bourgeois, D Armstrong

“…The present report describes a young woman with no previous gastrointestinal complaints who was initially diagnosed with postinfective irritable bowel syndrome (IBS) after a confirmed case of Campylobacter jejuni enteritis. …”
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Expression of TRP Channels in Colonic Mucosa of IBS-D Patients and Its Correlation with the Severity of the Disease by Li Cheng, Qing-Qing Luo, Sheng-Liang Chen

“…Lots of researches have endeavored to elucidate the pathogenetic mechanism of visceral hypersensitivity in order to guide the therapy of diarrhea predominant-irritable bowel syndrome (IBS-D). Transient receptor potential (TRP) channels and their role in visceral nociception have been vastly investigated. …”
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Psychobiotic effects of probiotics and prebiotics by V. T. Ivashkin, K. V. Ivashkin

“…The proof of possible immunologic effects of probiotics at irritable bowel syndrome that is associated with gut-brain signal axis disorders and microbiome changes was received. …”
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A novel framework for assessing causal effect of microbiome on health: long-term antibiotic usage as an instrument by Nele Taba, Krista Fischer, Estonian Biobank Research Team, Elin Org, Oliver Aasmets

“…We apply the AB-IVR method on the Estonian Biobank data and show that the microbiome has a causal role in numerous diseases including migraine, depression and irritable bowel syndrome. We show with a plethora of sensitivity analyses that the identified causal effects are robust and propose ways for further methodological developments.…”
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NUCB2/Nesfatin-1 Regulation of Chronic Visceral Hyperalgesia by Qiaoyan Gu, Yuan Lei, Jianming Wu, Ting He, Juanjuan Li, Shanshan Song

“…We previously described that different concentration Nucleobindin-2 (NUCB2)/Nesfatin-1 gradients differently regulated visceral hypersensitivity in irritable bowel syndrome. Therefore, this study is aimed at evaluating the effect of NUCB2/Nesfatin-1 on model rats with chronic visceral hyperalgesia. …”
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Evaluation of the functional gastrointestinal diseases concept from standpoints of Rome IV (2016) diagnostic criteria (review) by D. N. Andreyev, A. V. Zaborovsky, A. S. Trukhmanov, I. V. Mayev, V. T. Ivashkin

“…In the new edition of Rome criteria the management approach to patients with sphincter of Oddi dysfunction is specified, along with diagnostic criteria of functional dyspepsia and irritable bowel syndrome. Conclusion. The classification of FGID is revised in updated Rome criteria, diagnostic features of several nosological entities were specified.…”
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