Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity by Yujia Zhao, Dan Liu, Wenguang Yang, Wangxiao He, Jin Yan, Leiqing Yao

“…In order to enable internalization into tumor cells, supramolecular engineering techniques were employed through terminal modification involving sulfydryl and monovalent gold ion (Au(I)), both facilitating self-assembly of modified PEPPDL1 into supramolecular nanospheres termed CTAC-PDL1 driven by aurophilic interaction. …”
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The development of a kinetic biotic ligand model to predict acute toxicity of Gadolinium for Daphnia magna by Marion Revel, Qiao-Guo Tan, Andrew Hursthouse, Susanne Heise

“…Its acute toxicity depends on its free ion concentrations (Gd3 +), which is directly related to chemical speciation. …”
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Transfer of optogenetic vectors into the brain of neonatal animals to study neuron functions during subsequent periods of development by D. A. Lanshakov, U. S. Drozd, T. A. Zapara, N. N. Dygalo

“…Optogenetics, that is, the control of cell activity using light-sensitive ion channels opsins with light of a specific wavelength, is increasingly being used to study activities and functions of neurons. …”
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Ethnicity-specific distribution of <em>TRPM8</em> gene variants in Eurasian populations: signs of selection by T. A. Potapova, A. G. Romashchenko, N. S. Yudin, M. I. Voevoda

“…The TRPM8 gene encodes the ion channel, which is a cold receptor in afferent neurons of the mammalian somatosensory system. …”
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Synthesis and Spectroscopic and Biological Activities of Zn(II) Porphyrin with Oxygen Donors by Gauri Devi Bajju, Sujata Kundan, Madhulika Bhagat, Deepmala Gupta, Ashu Kapahi, Geeta Devi

“…Absorption spectra show two principal effects: a red shift for phenols bearing substituted electron releasing groups (−CH3, −NH2) and blue shift for phenols bearing electron withdrawing groups (−NO2, −Cl) relative to Zn-t(p-CH3) PP, respectively. 1H NMR spectra show that the protons of the phenol ring axially attached to the central metal ion are merged with the protons of the porphyrin ring. …”
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Simultaneous Determination of B1, B2, B3, B6, B9, and B12 Vitamins in Premix and Fortified Flour Using HPLC/DAD: Effect of Detection Wavelength by Y. Albawarshi, A. Amr, K. Al-Ismail, M. Shahein, M. Majdalawi, M. Saleh, A. Khamaiseh, B. El-Eswed

“…The method reported in the present work does not require any sample cleanup/preconcentration steps, and chromatographic elution was achieved in 9.3 min without the need for ion-pairing reagents.…”
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Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice by Xiaolong Fu, Linqing Zhang, Yecheng Jin, Xiaoyang Sun, Aizhen Zhang, Zongzhuang Wen, Yichen Zhou, Ming Xia, Jiangang Gao

“…MYH14 is a member of the myosin family, which has been implicated in many motile processes such as ion-channel gating, organelle translocation, and the cytoskeleton rearrangement. …”
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Integration of NMR and NMRC in the Investigation of the Pore Size Distribution of Tight Sandstone Reservoirs: A Case Study in the Upper Paleozoic of Dongpu Depression by Ning Zhu, Suping Yao, Xuejun Wang, Binfeng Xia, Yunxian Zhang

“…An integration analysis comprising X-ray diffraction (XRD), three beams of argon ion (TIB) polishing approach, scanning electron microscopy (SEM), high-pressure mercury intrusion (HPMI), nuclear magnetic resonance (NMR), and nuclear magnetic resonance cryoporometry (NMRC) was applied to determine the pore structure of the tight sandstone reservoirs in the Upper Paleozoic of Dongpu Depression as well as their relationship with the physical properties of the reservoirs. …”
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FPR1 affects acute rejection in kidney transplantation by regulating iron metabolism in neutrophils by Peiyuan Li, Wenbin Ji, Baotong Zhang, Haowen Jia, Jinmiao Wang, Zhaonan Sun, Yifan Wang, Weiwei Wang, Feng Qi

“…At the cellular level, blocking FPR1 inhibited the activation of the ERK1/2 pathway, decreased ferrous ion content, affected the expression of iron metabolism-related proteins, and suppressed the formation of NETs. …”
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Commissioning and analysis of new desulfurization wastewater treatment system in a coal-fired power plant by LIU Guidong, HU Yangyang, WANG Jing, CHEN Yang, WANG Zhiyong, DANG Yulu, XU Hao

“…In a desulfurization wastewater renovation project of a coal-fired power plant in Shandong Province, the original triple-tank process was replaced by integrated high efficiency clarification process to treat the desulfurization wastewater, with suspended solids of 13 650 mg/L, CODCr of 350 mg/L and heavy metal ion concentration exceeding the standard. The basic chemical dosage could be determined by laboratory test. …”
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Biochemistry of the Thrombin-Like TLBpic and Its Purification from Bothrops pictus “Jergon de la Costa” (Reptilia: Viperidae) by Victor Ludgardo Álvarez Tohalino, Hugo Guillermo Jiménez Pacheco, Juan Raúl Jesús Zumaran Farfán, Pavel Kewin Delgado Sarmiento, Paulino Rodolfo Zegarra Panca

“…In the present study, a fraction with serinoprotease and coagulant activity has been purified on fibrinogen, called TLBpic, using a cationic ion exchange chromatographic system coupled to an HPLC system. …”
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Multi-component screening coupled with ultrasound-assisted green extraction based on HPLC-HRMS for bio-actives analysis in saffron (Crocus sativus L.) by Shouying Wang, Yiqing Song, Miaomiao Chen, Bing Bai, Lin Zhou, Changyan Zhou, Yongchun Zhang, Zhiying Huang, Wenshuai Si

“…A database of 115 bio-actives from seven subclasses, including information on retention time, parent ion m/z, fragment m/z, and isotopic fit, was established, and an instrumental method for simultaneous analysis of these targets was optimised. …”
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A Nitrogen-Rich Covalent Triazine Framework as a Photocatalyst for Hydrogen Production by Ruizhi Gong, Liuliu Yang, Shuo Qiu, Wan-Ting Chen, Qing Wang, Jiazhuo Xie, Geoffrey I. N. Waterhouse, Jing Xu

“…Further, as a nitrogen-rich porous 2D material, CTF-CN represents a potential platform for the development of novel electrode material for fuel cells and metal ion batteries.…”
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Synthesis of Highly Sulfonated Poly(arylene ether) Containing Multiphenyl for Proton Exchange Membrane Materials by Yi-Chiang Huang, Ruei-Hong Tai, Hsu-Feng Lee, Po-Hsun Wang, Ram Gopal, Chun-Che Lee, Mei-Ying Chang, Wen-Yao Huang

“…Subsequent to sulfonation, solvent-casting membranes were provided ion exchange capacity (IEC) values ranging from 0.39 to 2.90 mmol/g. …”
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Chemical Characterization of Sub-micron Aerosols during New Particle Formation in an Urban Atmosphere by Vijay P. Kanawade, Sachchida N. Tripathi, Abhishek Chakraborty, Huan Yu

“…Moreover, the increased proportion of organic ions, m/z 44 (CO2+), on these days suggested the presence of less volatile, highly oxidized OAs (LV-OOAs), revealing that the growth of new particles was mainly due to the condensation of low-volatility organic species. …”
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Metal-Based Antibacterial and Antifungal Agents: Synthesis, Characterization, and In Vitro Biological Evaluation of Co(II), Cu(II), Ni(II), and Zn(II) Complexes with Amino Acid-Der... by Zahid H. Chohan, M. Arif, Muhammad A. Akhtar, Claudiu T. Supuran

“…Ligands (L1)–(L5) were derived by condensation of β-diketones with glycine, phenylalanine, valine, and histidine and act as bidentate towards metal ions (cobalt, copper, nickel, and zinc) via the azomethine-N and deprotonated-O of the respective amino acid. …”
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Desert Dust Outbreaks over Mediterranean Basin: A Modeling, Observational, and Synoptic Analysis Approach by F. Calastrini, F. Guarnieri, S. Becagli, C. Busillo, M. Chiari, U. Dayan, F. Lucarelli, S. Nava, M. Pasqui, R. Traversi, R. Udisti, G. Zipoli

“…Furthermore, physical and chemical analyses (PIXE analysis and ion chromatography) were used to measure the concentration of all soil-related elements to quantify the contribution of dust particles to PM10. …”
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Investigation of Mechanical and Tribological Characteristics of Medical Grade Ti6al4v Titanium Alloy in Addition with Corrosion Study for Wire EDM Process by S. Prakash, C. S. Abdul Favas, I. Ameeth Basha, R. Venkatesh, M. Prabhahar, V. P. Durairaj, K. Gomathi, Haiter Lenin

“…Metals used in biomedical applications are frequently coated to prevent oxidation and metallic ion release, both of which can be harmful due to toxic effects. …”
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Multi-scale characterization of tight carbonate rocks based on digital cores by Changsheng Wang, Changsheng Wang, Lili Tian, Lili Tian, Chuanrui Sun, Chuanrui Sun, Yuwei Deng, Yuwei Deng, Ying Zhou, Ying Zhou, Xin Nie, Xin Nie

“…This study takes tight carbonate core samples in the fourth member of the Ordovician Majiagou Formation in the Ordos Basin as the research object, and the rock physics experiments, computed tomography (CT), high resolution large-scale backscatter scanning electron microscopy (MAPS), quantitative evaluation of minerals by scanning electron microscopy (QEMSCAN) and focused ion beam-scanning electron microscopy (FIB-SEM) was utilized to characterize the pore structure from micrometer to nanometer, revealing the main mineral composition, and systematically analyzing the relationship between different mineral and pore structures. …”
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Metrological studies of the characteristics of multilayer surface coatings using synchrotron radiation by A. S. Sigov, O. A. Minaeva, S. I. Anevsky, A. M. Lebedev, R. V. Minaev

“…To form multilayer nanostructures directly on the receiving surface of photodetectors, an ion-plasma sputtering module is used. The optical scheme of the channel provides for the possibility of using monochromators of grazing incidence for the range of photon energies from 25 to 100 ev and normal incidence for the range of photon energies from 4 to 25 ev. …”
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