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1281
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation
Published 2025-01-01“…Methods Firstly, the network pharmacology was used to screen the RosA targets, and LUAD-related differential expressed genes (DEGs) were acquired from the GEO database. The intersection of LUAD regulated by RosA (RDEGs) was obtained through the Venn diagram. …”
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1282
Unveiling prognostic value of JAK/STAT signaling pathway related genes in colorectal cancer: a study of Mendelian randomization analysis
Published 2025-02-01“…Results The 3,668 JAK-STAT-DEGs were obtained by intersection of 5826 CRC-DEGs and 9766 JAK-STAT key module genes. …”
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1283
Exploration of the mechanism of Lithospermum erythrorhizon oil in treating atopic dermatitis based on network pharmacology and experimental validation of the PI3K-Akt pathway regul...
Published 2025-01-01“…Common targets were selected by intersecting these with AD-related targets from GeneCards. …”
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1284
Co-occurring climate events and environmental justice in California, 2018–2019
Published 2025-01-01“…We defined county-day wildfire burn zone disasters when an active wildfire burn zone intersected a county, burned 1+ structures, killed a civilian, or received a Federal Emergency Management Agency Fire Management Declaration, and overlapped with a community. …”
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1285
Revealing Land-Use Dynamics on Thermal Environment of Riverine Cities Under Climate Variability Using Remote Sensing and Geospatial Techniques
Published 2024-12-01“…Finally, Warming and Cooling Transition (WCT) maps were generated by intersecting LST classes with 2000 as the baseline. Results indicated a rise in LST from 32.39 °C in 2000 to 45.63 °C in 2020. …”
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1286
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1287
Le port antique de Chelles (Seine-et-Marne) : une course après la rivière
Published 2020-12-01“…This resulted in the intersecting meander that can be recognized today and which is already visible on 18th c. maps. …”
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1288
Inequalities in total fertility rate in Sierra Leone, 2008–2019
Published 2025-02-01“…These implications collectively suggest that policymakers should adopt an integrated approach that combines economic empowerment, educational initiatives, and provincial development strategies to address these intersecting inequalities in TFR effectively.…”
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1289
YOLOX-SwinT algorithm improves the accuracy of AO/OTA classification of intertrochanteric fractures by orthopedic trauma surgeons
Published 2025-01-01“…Results: The mean average precision at the intersection over union (IoU) of 0.5 (mAP50) for subgroup detection reached 90.29%. …”
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1290
Marine sponge symbiotic bacterial bioremediation against heavy metal pollutants in tiger prawns; Penaeus monodon culture medium
Published 2024-07-01“…The health of the tiger prawns was evaluated by observing signs of tissue damage.FINDINGS: Among all the treatments, Treatment I with copper ion exposure had the highest average specific growth rate of the tiger prawns in terms of weight and body length, followed by Treatment II with lead ion exposure and Treatment III with a combination of both pollutants (the lowest). The intersection of copper and lead ion concentrations in the tiger prawns and cultivation media occurred in the cultivation period of 15–20 days. …”
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1291
Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Valid...
Published 2024-12-01“…Moreover, there were 99 intersecting genes between GQD and CAC. The core targets of GQD contained NFKB1, IL1B, IL6, TLR4, and TNF, and GQD reduced inflammation by inhibiting the TLR4 signaling pathway. …”
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1292
The Identification of FN1 as an Early Diagnostic Marker for Recurrent Abortion by Single-Exosome Profiling
Published 2025-02-01“…After PBA treatment, samples were analyzed for single exosomes, and exosomes from each group were compared using volcano plots, dot plots, and ROC curves.Results: By intersecting all significantly differentially expressed genes obtained from comparisons between the normal pregnancy control group and the recurrent abortion group, including the RA before abortion, RA after abortion, and RA non-pregnancy groups, we identified seven shared differential genes: FN1, APIPOQ, CDH13, DSG1, CLDN4, CD36, and ULBP3. …”
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1293
Management of mangrove landscape and ecosystem for ecotourism
Published 2024-10-01“…BACKGROUND AND OBJECTIVES: Mangroves have high potential for advancing ecotourism because of their position at the intersection of land and sea. Many studies have reported that mangroves and coastal environments are the right places for the development of sustainable ecotourism. …”
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1294
Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m6A-dependent manner
Published 2025-02-01“…Further MeRIP-seq and RIP-seq revealed 197 genes interacting with IGF2BP3, downregulated at mRNA and m6A levels after NC treatment, primarily associated with multiple metabolism-related pathways. Through intersection analysis, we pinpointed 30 potential metabolic target genes regulated by NC through IGF2BP3. …”
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1295
Exploring the Mechanism of Canmei Formula in Preventing and Treating Recurrence of Colorectal Adenoma Based on Data Mining and Algorithm Prediction
Published 2025-02-01“…Network topology analysis and bioinformatics analysis were performed on 164 intersecting core targets. Molecular docking and qPCR analysis revealed that CMF downregulates angiotensin II type 1 receptor (AT1R) and regulated interleukin-8 (CXCL8) and matrix metalloproteinase 13 (MMP13) within the REN/Ang II/AT1R axis of the renin-angiotensin signaling pathway, thereby preventing and treating CRA. …”
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1296
Review and Prospect of Research on Urban Walking Safety and Environmental Influencing Factors Thereof
Published 2025-02-01“…Thirdly, from the perspective of research hotspot, it can be seen form the three dimensions of activity safety, traffic safety and security that, different levels of environmental elements such as neighborhoods, streets and intersections, have important influence on walking safety. …”
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1297
Integrated bioinformatics analysis to explore potential therapeutic targets and drugs for small cell carcinoma of the esophagus
Published 2025-01-01“…Then, up- and down-regulated genes were intersected with the oncogenes and the tumor suppressor genes respectively, to obtain the differentially expressed onco/tumor suppressor genes in SCCE. …”
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1298
Efectos de los factores de edificabilidad sobre la productividad laboral de moldajes de vigas en fundaciones The effects of buildability factors on formwork labor productivity of g...
Published 2010-08-01“…Therefore, the objective of this research is to investigate and quantify the effects and relative influence of the following buildability factors on formwork labor efficiency of this activity: (a) variability of beam sizes; (b) beam sizes; and (c) number of joints formed at beams intersections. To achieve this objective, a large volume of productivity data was collected and analyzed using the multiple regression method. …”
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1299
Use of Digital Health Technologies for Dementia Care: Bibliometric Analysis and Report
Published 2025-02-01“…Overall, the number of publications covering the intersection of DHTs and dementia has increased steadily over time. …”
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1300
RETRACTED: Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study
Published 2023-05-01“…The STRING database and Cytoscape were utilized to create protein–protein interaction (PPI) networks and further screening of core targets.Results: The intersection of target genes and core target genes of the phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) pathway was enriched, the top-five core target genes were selected, and the binding affinity of corresponding compounds to the top-five core targets was analyzed using molecular docking. …”
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