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1261
Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis
Published 2025-02-01“…Based on these key genes, we carried out nomogram construction, enrichment and immune analyses, regulatory network mapping, drug prediction, and expression verification.Results: 27 DE-IFRGs were identified by intersecting 256 DEGs, 1793 immune-related genes, and 1019 inflammation-related genes. …”
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1262
Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation
Published 2025-01-01“…We aimed to establish the Anoikis-related gene signature in CKD by bioinformatics analysis.Methods: We retrieved 3 datasets from the Gene Expression Omnibus (GEO) database to obtain differentially expressed genes (DEGs), followed by Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, Gene Set Enrichment Analysis (GSEA) and Gene Set Variation Analysis (GSVA) of them, which were intersected with Anoikis-related genes (ARGs) to derive Anoikis-related differentially expressed genes (ARDEGs). …”
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1263
Performance Evaluation of Large Language Models in Cervical Cancer Management Based on a Standardized Questionnaire: Comparative Study
Published 2025-02-01“…Interpretability analysis showed that prompts improved alignment with human annotations for proprietary models (median intersection over union 0.43), while medical-specialized models exhibited limited improvement. …”
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1264
Factors influencing gender and youth integration in agricultural research and innovation in Africa
Published 2024-02-01“…Consequently, there is a need for increased investment in translating the products and processes of R&I interventions into opportunities for entrepreneurship and employment. Intersectional lens is also needed for meaningful involvement of different community groups in the R&I interventions, and for reducing the different causes of inequalities and marginalization that hamper transformation of Africa’s food system. …”
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1265
Syntheses and structures of two coordination polymers formed by Ni(cyclam)2+ cations and sulfate anions
Published 2025-02-01“…As a result of the C—H...O hydrogen bonds between the methylene groups of the macrocyclic ligands and the non-coordinated O atoms of the sulfate anion, the coordination-polymeric chains in I are arranged in the two-dimensional layers oriented parallel to the (010) and (101) planes, the intersection of which provides the three-dimensional coherence of the crystals. …”
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1266
Bergapten alleviates senescence of chondrocytes in osteoarthritis
Published 2025-02-01“…The obtained targets were intersected with Venny2.1.0, protein-protein interaction (PPI) analysis was performed using the STRING database, and molecular docking was conducted by AutoDock Vina. …”
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1267
Co-Optimization of Operational and Intelligent Completion Parameters of CO<sub>2</sub> Water-Alternating-Gas Injection Processes in Carbonate Reservoirs
Published 2025-01-01“…First, a simulation method is developed by using Petrel and Intersect. Then, a series of simulations are performed to prove the viability of intelligent completions and to investigate the effects of the timing and duration of the CO<sub>2</sub> WAG injection, as well as the type, number, and placement of intelligent completion devices on the performance of a CO<sub>2</sub> WAG injection by MRC wells. …”
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1268
The revival of spiritual practices: factors influencing the “seeking deities and offering prayers” behavior of China’s Generation Z on social media in an atheistic context
Published 2025-01-01“…IntroductionOver the past decade, there has been a growing focus on the study of how religion and technology intersect, particularly within the field of digital religion studies. …”
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1269
Cohort profile: Noncommunicable diseases and ideal cardiovascular health among people living with and without HIV in Zambia and Zimbabwe (NCDzz cohort)
Published 2025-02-01“…Purpose The NCDzz study is a prospective cohort of people living with and without HIV attending primary care clinics in Zambia and Zimbabwe and was established in 2019 to understand the intersection between noncommunicable diseases (NCDs) and HIV in Southern Africa. …”
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1270
Innovative Model of Socio-Professional Development of a Student’s Personality
Published 2020-04-01“…The mechanism of the model implementation is to build an individual student professional perspective aimed at practical action in order to improve the level of qualification, ability to work, enrichment of professional and personal qualities and behavioural patterns.Scientific novelty of the present research consists in the formation of interdisciplinary scientific knowledge (at the intersection of psychology, pedagogy, philosophy, occupational studies) on the methodology of the modelling, organisation and content of professional education taking into account modern challenges and demands of the digital economy. …”
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1271
Autistic and transgender/gender diverse people’s experiences of health and healthcare
Published 2025-01-01“…Greater recognition of challenges and reasonable adjustments are essential for people with marginalized, intersectional identities in clinical practice.…”
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1272
A synthesis of academic literature on eco-spirituality
Published 2024-10-01“…This study critically examines the concept of eco-spirituality, exploring its intersection with spirituality and environmental concerns and its profound implications for contemporary society. …”
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1273
Comparative Evaluation of AI-Based Multi-Spectral Imaging and PCR-Based Assays for Early Detection of <i>Botrytis cinerea</i> Infection on Pepper Plants
Published 2025-01-01“…The dataset included hyperspectral images at discrete wavelengths (460 nm, 540 nm, 640 nm, 775 nm, and 875 nm) from derived vegetation indices (CVI, GNDVI, NDVI, NPCI, and PSRI) and from RGB. At an Intersection over Union with a 0.5 threshold, the Mean Average Precision (mAP50) achieved by the leaf-segmentation solution YOLOv11-Small was 86.4%. …”
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1274
Buffalo whey proteins performance at the oil/water interface: rheology characterization of the interfacial films
Published 2023-11-01“…Plate tensiometry showed that πeq of BWPC and WPC solutions increased from 9.9 to 16.7 mN/m and 11.5 to 15.0 mN/m, respectively, and conform protein concentration increased. An intersection between π – concentration isotherms was observed, indicating that below protein concentration of 1.3x10-2%, the πeq of WPC was higher than BWPC. …”
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1275
Animal experiments and network pharmacology to explore the anti-inflammatory mechanism of dapagliflozin in the treatment of polycystic ovary syndrome
Published 2025-12-01“…Furthermore, network pharmacology identified 26 intersecting target genes relevant to inflammation in PCOS, with subsequent molecular docking simulations revealing strong binding affinities of dapagliflozin to key targets, including AKT1 and TP53.Conclusions These findings suggest that dapagliflozin exerts beneficial effects on PCOS by ameliorating ovarian dysfunction and reducing inflammation. …”
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1276
The AFFIRM Framework for gender-affirming care: qualitative findings from the Transgender and Gender Diverse Health Equity Study
Published 2025-02-01“…Themes about gender-affirming care coalesced into the acronym AFFIRM: (1) Affirms in individual interactions: Participants called for affirmation of TGD identity, lived expertise, and competent TGD providers and staff. (2) Flexible and accessible: Participants expressed the need for gender-affirming care to be available beyond urban population-specific clinics, in a timely fashion without long wait lists, and in a community-centered manner such as offering non-traditional times and settings. (3) Fights systemic oppression: Participants emphasized the need for providers and health systems to eliminate gatekeeping practices for gender-affirming care and create care models that resist intersecting oppressive systems such as racism and cisgenderism. (4) Interacts with community: Patients desired intentional interaction with TGD community to holistically address health and unmet gender affirmation needs. (5) Retains patients in care: Patients shared the need to collaboratively identify and problem-solve obstacles to gender-affirming care with providers and healthcare systems to optimize TGD-specific retention strategies. (6) Multidisciplinary: Patients called for interdisciplinary teams with co-located services such as primary care and mental healthcare with letter-writing for surgical care, and incorporation of peer navigators to meet the broader social, health, and well-being needs of TGD people. …”
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1278
Association of lung health and cardiovascular health (Life’s Essential 8)
Published 2025-02-01“…BackgroundCardiorespiratory health issues often intersect. This study explored the relationship between lung health and the recently updated Cardiovascular Health Measure (Life’s Essential 8).MethodsData from the 2007–2018 National Health and Nutrition Examination Survey (NHANES) were analyzed. …”
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1279
The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome
Published 2025-01-01“…The immune-mediated, inflammatory, and fibrosing intersections of IgG4-RD and systemic sclerosis raised a question about platelets’ role in IgG4-RD. …”
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1280
Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease
Published 2025-02-01“…The differentially expressed genes (DEGs) in the key cell and GSE5281 datasets were identified, and the MRGs in GSE5281 were selected via weighted gene coexpression network analysis. After intersecting two sets of DEGs and MRGs, we performed Mendelian randomization analysis to identify the MRGs causally related to AD. …”
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