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1241
Recent trends in research on the role of cholesterol in leukemia: a bibliometric and visualization study
Published 2025-01-01“…Further exploration at the intersection of cholesterol metabolism and leukemia requires multidisciplinary collaboration.ConclusionThis bibliometric study delineates the evolving research landscape on cholesterol’s role in leukemia, pinpointing emerging trends and future research directions to inform effective therapeutic strategies.…”
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1242
Taung and beyond: The mining history, geology and taphonomy of Australopithecus in South Africa
Published 2025-02-01“…The South African Fossil Hominid sites provide a unique opportunity to expand our understanding of the intersection between human evolution and changing environmental conditions, as the karstic landscape and remnant cave systems preserve both fossils and sedimentary archives of past environmental change. …”
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1243
Discrete Element Modeling on Mechanical Behavior of Heterogeneous Rock Containing X-Shaped Fissure under Uniaxial Compression
Published 2020-01-01“…Based on the experimental results of an intact rock specimen under uniaxial compression, particle flow code (PFC2D) was adopted to carry out a discrete element modeling (DEM) for the mechanical behavior of heterogeneous rocks containing X-shaped fissures (two intersecting symmetric single fissures) under uniaxial compression. …”
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1244
Comorbidities and neurosurgical interventions in a cohort with connective tissue disorders
Published 2025-01-01“…We evaluated relationships between diagnoses and surgical interventions by multivariate correlation and intersection plots using the UpSetR package.ResultsOf 759 individuals, we excluded 42 based on incomplete data. …”
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1245
Screening of necroptosis-related genes and evaluating the prognostic capacity, clinical value, and the effect of their copy number variations in acute myeloid leukemia
Published 2025-01-01“…Methods Necroptosis-related differentially expressed genes (NRDEGs) were identified after intersecting differentially expressed genes (DEGs) from the Gene Expression Omnibus(GEO) database with NRGs from GeneCards, the Molecular Signatures Database (MSigDB) and literatures. …”
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1246
The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs)
Published 2025-01-01“…The functional versatility of Atoh1 prompted us to test the possibility that Atoh1 may intersect the dental pulp stem cell (DPSC) gene regulatory network governing odontogenic differentiation. …”
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1247
Analysis of the mechanism of Zangjiangzhi capsule in the treatment of hyperlipidemia based on its ingredients identified by UHPLC-Q-Exactive-Orbitrap-MS
Published 2025-01-01“…Among them, 158 targets intersected with the HLP target network. Network pharmacology analysis showed that MAPK1, PPAR-α, RXRA, HSP90AA1, PIK3R1, AKT1, PIK3CA, IL6, TNF, and ESR1 are the key targets of action. …”
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1248
The impact of the COVID-19 pandemic on the research activity and working experience of clinical academics, with a focus on gender and ethnicity: a qualitative study in the UK
Published 2022-06-01“…Participants described differential experiences based upon their gender and ethnicity, noting intersectional identities.Conclusions While there have been some positives afforded to clinical academics, particularly for new avenues of research, COVID-19 has negatively impacted workload, future career intentions and mental health. …”
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1249
Perspectives on which health settings geriatricians should staff: a qualitative study of patients, care providers and health administrators
Published 2025-01-01“…Acute care was reported to be most important by some because no other care provider has the intersection of acute medicine skills with geriatric training. …”
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1250
Comprehensive Analysis of Competing Endogenous RNA Network Focusing on Long Noncoding RNA Involved in Cirrhotic Hepatocellular Carcinoma
Published 2021-01-01“…A total of 74 lncRNAs, 36 intersection miRNAs, and 949 mRNAs were differentially expressed in cirrhotic HCC samples compared with cirrhosis samples. …”
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1251
Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease
Published 2025-02-01“…Methods In this study, the intersection of the differentially expressed genes (DEGs) from the GSE109887 cohort, immune-related genes (IRGs) obtained from WGCNA analysis, and mitochondria-related genes (MRGs) was taken to identify mitochondria–immune-related genes (MIRGs). …”
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1252
Unveiling new therapeutic horizons in rheumatoid arthritis: an In-depth exploration of circular RNAs derived from plasma exosomes
Published 2025-01-01“…A diagnostic xgboost model was developed using common hub genes identified by random forest and least absolute shrinkage and selection operator (LASSO), with intersection genes derived from overlapping machine learning-selected genes. …”
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1253
Compound identification of Shuangxinfang and its potential mechanisms in the treatment of myocardial infarction with depression: insights from LC-MS/MS and bioinformatic prediction
Published 2025-01-01“…All the targets were intersected to construct the Protein-Protein Interaction (PPI) network on Metascape platform and the herb-compound-target (HCT) network on Cytoscape, to identify the hub targets. …”
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1254
Optimizing composite ecological networks through Synergistic risk Management, ecological Conservation, and recreational Integration: A case study of Beijing’s shallow mountain regi...
Published 2025-01-01“…Key findings include: (1) The study identified 49 ecological source sites and 43 recreational source sites, along with 105 ecological corridors and 80 recreational corridors; (2) This research selected 54 ecological pinch points, 137 intersections between ecological and recreational corridors, and 283 alternative composite source points combining ecological and recreational resources; (3) This paper selected 140 composite source points and the construction of 128 composite corridors, 161 potential corridors, 371.82 km2 of risk prevention area, and 468.74 km2 of ecological protection area; (4) Network analysis revealed that the composite ecological network demonstrated superior closure, complexity, and connectivity compared to traditional methods; (5) This study proposed an optimization strategy for ecological spatial networks, based on the “patch-corridor-substrate” theory of landscape ecology, emphasizing 3 levels: ecological restoration, ecological protection, and the development of recreational systems. …”
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1255
Integrated bioinformatics analysis identified cuproptosis-related hub gene Mpeg1 as potential biomarker in spinal cord injury
Published 2025-01-01“…Hub genes were identified at the intersection of PPI analysis results from two modules and cuproptosis-related DEGs. …”
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1256
Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for...
Published 2024-12-01“…Pathway and functional enrichment revealed key biological processes and pathways like p53 signaling, and cell cycle. The intersection of these DEGs with genes involved in cell cycle and p53 signaling, identified 23 common genes that were used for constructing a PPI network. …”
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1257
ENTREPRENEURSHIP OF MEMORY IN PUBLIC SPACE AND SOCIAL COMMUNICATION: A POSTCOLONIAL APPROACH IN TIME OF WAR
Published 2024-12-01“…In the discourse of the creative industries and the creative economy, it is appropriate to consider the model of the experience economy, which operates creatively in the context of the "memory of emotional experience" and strategically intersects with the discourse of the politics of memory. …”
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1258
Design of Command and Dispatch System for Automatic Reading of Meter Images in Substations by UAV Inspection Photos
Published 2024-01-01“…The experimental results show that in two datasets, The mean average precision of 50 (mAP50) accuracy of the YOLOv6n model using this method reached 99.71% and 98.60%, respectively, and the inference speed of a single image was 17.1[Formula: see text]ms and 13.2[Formula: see text]ms, respectively. The mean intersection over union (mIoU) of the image segmentation model reached 82.00%, 74.73%, 73.50%, 82.26% and 73.20%, respectively, and the single segmentation speed reached 33.7[Formula: see text]ms. …”
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1259
A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma
Published 2025-02-01“…Results Three differentially expressed ARGs (CDC25C, E2F1 and RBL2) with prognostic value were identified by the intersection of multiple machine learning algorithms. …”
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1260
Double degree programs and education for sustainable development implementation: Experience of Ukrainian and UK universities cooperation in wartime
Published 2025-02-01“…Loss of human capital, including educational losses, becomes more relevant from the perspective of further sector development.This paper explores the intersection of DDP implementation and the implementation of Education for Sustainable Development (ESD), focusing on faculty members’ experiences within the Twinning Initiative framework. …”
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