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1221
Shared Genes and Pathways in Ulcerative Colitis and Ankylosing Spondylitis: Functional Validation and Implications for Diagnosis
Published 2025-02-01“…The DEGs from both datasets were intersected to identify common DEGs, relevant to both UC and AS, which were used in receiver operating characteristic (ROC) curve analysis to confirm key genes in the shared pathway. …”
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1222
Studying gender in the experiences of patients with heart failure: A scoping review of qualitative studies and methodological recommendations
Published 2025-01-01“…To this end, researchers should clearly state their conceptual approach to gender and analyse their findings using state-of-the-art gender theoretical frameworks and intersectional approaches. Ultimately, this will allow the development of tailored and effective clinical care.…”
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1223
Immune gene features and prognosis in colorectal cancer: insights from ssGSEA typing
Published 2025-02-01“…Between the two groups, a total of 1550 DEGs were identified and 395 differentially expressed immune-related genes (DE-IRGs) were identified by intersection with 2483 IRGs. The DE-IRGs of the high Immunity group were dominated by Cytokine receptor interactions, chemokine signaling pathways and immune cell-mediated cytotoxicity, and molecule function of immune effector process. …”
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1224
Retrospective analysis of scientific and psychological concepts of domestic violence
Published 2023-12-01“…According to scientists, violence is associated with the use of deliberate physical, psychological, financial and material pressure on a person, as most cases of domestic violence intersect with psychological pressure and exploitation. …”
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1225
GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease
Published 2025-02-01“…The glutathione peroxidase 3 (GPX3) gene emerged as a pivotal hub gene, with its expression significantly altered in both TBI and PD datasets.Conclusion: This study underscores the critical role of GPX3 in the molecular intersection of TBI and PD, suggesting it as a novel and potential therapeutic target, offering new insights into potential therapeutic strategies.Keywords: traumatic brain injury, Parkinson’s disease, bioinformatics, oxidative stress, mitochondrial dysfunction, neurodegenerative diseases…”
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1226
Research on path planning for coal mine rescue robots
Published 2024-12-01“…Next, a correction factor is incorporated into the cost function of the Bidirectional A* algorithm to ensure that the forward and backward search paths intersect, preventing them from diverging. Additionally, a dynamic weighting factor is added to the estimated cost function to eliminate irrelevant expanded nodes during pathfinding, thus improving search efficiency. …”
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1227
Structural Vulnerability Factors and Gestational Weight Gain: A Scoping Review on the Extent, Range, and Nature of the Literature
Published 2024-12-01“…Conclusions: Given the heterogeneity in findings across studies, adopting an intersectional approach may enhance our understanding of the complex interplay between SVFs and the social context in relation to GWG. …”
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1228
Deep Learning-Based Fully Automatic Segmentation of the Paranasal Sinuses in Chronic Rhinosinusitis Patients Using Computed Tomographic Images
Published 2025-01-01“…Testing results demonstrated that the model accurately identified the segmentation areas, achieving a Dice Similarity Coefficient of 92.8%, Intersection over Union of 86.64%, accuracy of 99.69%, precision of 92.63%, and recall of 93.22%. …”
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1229
Whole-transcriptome analysis reveals the characteristics of intramuscular fat circRNA expression and its associated network in grazing yaks of different months of age under cold st...
Published 2025-03-01“…Conclusions: Taking the intersection of the predicted circRNA target genes with the differential miRNAs for intramuscular fat in yaks of different months of age, we obtained two candidate ceRNA pairs that might be related to intramuscular fat deposition in yaks, and found that bta-let-7i might be related to fat deposition in yaks and might be regulated by X_85287959_85291068, and that X_85287959_85291068 could be a candidate circRNA to enhance the quality of yak meat. …”
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1230
Dicoumarol sensitizes hepatocellular carcinoma cells to ferroptosis induced by imidazole ketone erastin
Published 2025-02-01“…Differentially expressed genes were identified and intersected with the ferroptosis-related genes (FRGs) listed in the FerrDb database, yielding the identification of 13 distinct FRGs.ResultsA ferroptosis signature index model (Risk Score) was developed to predict HCC prognosis. …”
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1231
Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa)
Published 2025-01-01“…Then, genes in the highest co-expressed module were intersected with the up-regulated DEGs to construct a Protein-Protein Interaction network, resulting in 237 overlapping genes. …”
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1232
Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach
Published 2025-02-01“…However, the mechanism underlying the effects of SSA in prostate cancer treatment remains elusive.MethodsIn this study, a network pharmacology approach was applied to identify relevant targets from drug- and disease-related databases, and intersections were analyzed using Venny2.1 to construct a Protein-Protein interaction (PPI) interaction network. …”
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1233
Cost-efficient assignment panel for ducks. Setup of a cost-efficient assignment panel for duck populations.
Published 2024-09-01“…This SNP array is made of two libraries (one for the Muscovy duck, the other for the common duck which encompasses the Pekin duck), the intersection of which, after a preliminary elimination on the primer length, contained only 399 SNP that were considered a starting point to obtain a final list. …”
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1234
improving Pain mAnagement for childreN and young people attendeD by Ambulance (PANDA): protocol for a realist review. [version 3; peer review: 2 approved, 1 approved with reservati...
Published 2025-01-01“…Pain is a highly complex sensory and emotional experience. The intersection between acute pain, unwell CYP and the unpredictable pre-hospital environment is convoluted. …”
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1235
Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction
Published 2025-01-01“…It is crucial to analyse them from an intersectional perspective, considering the influence of multiple axes of inequality on health, in order to develop gender-sensitive strategies with a multidisciplinary approach.…”
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1236
Adverse outcome pathway-based assessment of pulmonary toxicity from the in vivo mixture of biocides dinotefuran and cetylpyridinium chloride
Published 2025-01-01“…We previously identified cetylpyridinium chloride and dinotefuran as a potential binary biocidal combination associated with pulmonary fibrosis, based on two intersecting adverse outcome pathways (AOPs) using the molecular initiating events (MIE) modeling method and in vitro testing. …”
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1237
HSRoadNet: Hard-Swish Activation Function and Improved Squeeze–Excitation Module Network for Road Extraction Using Satellite Remote Sensing Imagery
Published 2025-01-01“…Comparison experimental results indicate that, in various indicators, the proposed method performs serviceably, it, respectively, increased by 16.8%, 2.2%, 1.5%, and 8.5% over the suboptimal in <italic>F</italic>-score, global accuracy, class average accuracy, and recall ratio. The mean intersection over union (MIoU) value of the proposed method was the suboptimum with a disparity of 0.2% from the optimal. …”
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1238
FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression
Published 2025-01-01“…The Bioinformatics and Evolutionary Genomics web tool was employed to intersect the sets of shared microRNAs and their common targets. …”
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1239
Identification and validation of diagnostic genes IFI44 and IRF9 in insomnia-associated autoimmune uveitis
Published 2025-01-01“…PPI network analysis highlighted 10 key genes, CMap analysis identified 30 compounds, and WGCNA revealed 54 key genes and 30 compounds. Intersection of the above-mentioned key genes and compounds identified six genes and five compounds. …”
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1240
Grouting Mechanism in Water-Bearing Fractured Rock Based on Two-Phase Flow
Published 2021-01-01“…The optimization scheme of grouting was put forward, which adopted multiple grouting holes in the long side, and grouting in different directions and periods to avoid the possible problems of multihole intersection. The rationality and effectiveness of the proposed optimization method were verified through the calculation of water yield and analysis of cement composition from the drilling core in the grouted zone. …”
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