Mapping C. difficile TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling by Jennifer S. Ward, Karl J. Schreiber, John Tam, Ji-Young Youn, Roman A. Melnyk

“…Here, we used BioID to interrogate proximal interactors of the multi-domain Clostridioides difficile TcdB toxin. …”
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Knowledge, Attitudes, and Practices on Urinary Schistosomiasis among Primary Schoolchildren in Nelson Mandela Bay, South Africa by Sydlynn Dorné Hambury, Anna D. Grobler, Paula Ezinne Melariri

“…Bivariate and multivariate techniques were further used to analyse and describe the data and significant associations at p=0.05 were further interrogated using Cohen’s d and Cramér’s V, to determine the practical significance. …”
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A review of approaches to the integration of humanitarian and development aid: the case of drought management in the Horn of Africa by Tahira Shariff Mohamed, Todd Andrew Crane, Samuel Derbyshire, Guyo Roba

“…It surveys implications that arise in relation to the question of how best to address persistent drought in the Horn of Africa. Interrogating mechanisms for enhancing aid efficiency and effectiveness including crisis modifiers and contingency planning, the paper examines what progress has been made in transitioning from reactive, short-term emergency response to long-term development and what barriers still exist. …”
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Trends in Specialty Training and National Institutes of Health Funding Among Surgeon-Scientists by Gabriel Velez, MD, PhD, Vinit B. Mahajan, MD, PhD, Ronald J. Weigel, MD, PhD, MBA, Steven R. Lentz, MD, PhD

“…NIH Research Portfolio Online Reporting Tool Expenditures and Results was interrogated to identify a cohort of early-career academic surgeon-scientists receiving K-awards from 2011 to 2021. …”
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Le rôle des limites locales dans la sobriété énergétique : éclairages à partir du cas de l’autoconsommation collective en France by Jessica Zaphiropoulo

“…En se basant sur la littérature existante, cet article se propose d’utiliser une approche sociotechnique et la notion de script développée par Akrich pour explorer la manière dont les limites locales permettent d’interroger la capacité de l’ACC à proposer des alternatives au système énergétique conventionnel teintées de sobriété. …”
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Impact of Preoperative Daytime Sleepiness and Insomnia on Therapy Adherence and Neurostimulation Amplitude in Unilateral Hypoglossal Nerve Stimulation by Pordzik J, Ludwig K, Ruckes C, Gouveris H

“…Adherence was assessed by interrogating the impulse generator’s data at that time. …”
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Le respect de l’animal inscrit pour la première fois dans les programmes scolaires français à la rentrée 2024 : une avancée à encourager pour une protection interspécifique... by Aloïse Quesne

“…Il a en effet pour conséquence d’interroger et de renouveler la notion de « vivre ensemble », en promouvant la cohabitation harmonieuse du Vivant (homme, animal, nature). …”
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Epidemiology and Treatment Patterns of Fistulizing Crohn’s Disease in a Large, Real-World Australasian Cohort by Jack McNamara, William Wilson, Joseph L. Pipicella, Simon Ghaly, Jakob Begun, Ian C. Lawrance, Richard Gearry, Jane M. Andrews, Susan J. Connor

“…Methods: A large real-world cohort of people with inflammatory bowel disease under routine care was interrogated in August 2023. Current fCD was defined as fistula(e) on most recent clinical, radiologic or endoscopic investigation; prior fCD was defined as the resolution of fistula(e) on most recent documentation. …”
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Cross-Cultural Gender-Based Investigation of Filipino and Chinese Facebook Users’ Disagreement Strategies by Joan C. Ravago, John Arvin V. De Roxas, Joel M. Torres, Daisy O. Casipit, Mercedita M. Reyes

“…Results: Findings revealed that Filipino and Chinese participants employed different strategies, such as implicit performative strategies through non-elliptical expression and counterstatement with justification, declaration, and sarcasm, and indirect disagreement strategies through interrogative, declarative, and imperative statements. …”
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The multi-omics signatures of telomere length in childhood by Congrong Wang, Dries S. Martens, Mariona Bustamante, Rossella Alfano, Michelle Plusquin, Lea Maitre, John Wright, Rosemary R. C. McEachan, Johanna Lepeule, Remy Slama, Marina Vafeiadi, Leda Chatzi, Regina Grazuleviciene, Kristine B. Gutzkow, Hector Keun, Eva Borràs, Eduard Sabidó, Angel Carracedo, Georgia Escarami, Augusto Anguita-Ruiz, Dolors Pelegrí-Sisó, Juan R. Gonzalez, Martine Vrijheid, Tim S. Nawrot

“…The association of these latent components with early-life aging risk factors (child lifestyle, body mass index (BMI), exposure to smoking, etc.), were interrogated. Results After multiple-testing correction, only two CpGs (cg23686403 and cg16238918 at PARD6G gene) out of all the omics features were significantly associated with child telomere length. …”
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How far? Travel burdens for children admitted to hospitals in the Western Cape Province of South Africa by M Richards, D le Roux, D Pienaar

“…These findings could be further interrogated for people’s choices of facility and method of travel. …”
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Metagenomics: a new frontier for routine pathology testing of gastrointestinal pathogens by Nicola Z. Angel, Mitchell J. Sullivan, Areej Alsheikh-Hussain, Liang Fang, Samantha MacDonald, Alena Pribyl, Blake Wills, Gene W. Tyson, Philip Hugenholtz, Donovan H. Parks, Paul Griffin, David L. A. Wood

“…Conclusions The advantage of mNGS compared to other syndromic testing systems is the broad range of detectable targets and the ability to interrogate samples without clinician informed or assay specific bias. …”
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Les effets des normes de sexe chez les enseignant-e-s de l’école primaire by Céline Delcroix

“…Il s’agit aussi de s’interroger sur l’influence de la masculinisation dans l’activité proprement éducative puisque la place des femmes et des hommes dans la société affectent les métiers liées à la petite enfance, et pas seulement.Partant de cet état des lieux, j’ai pris pour objet de recherche les effets des normes de sexe chez les femmes et les hommes qui font le choix de devenir enseignant-e en primaire et comment ces rôles de sexe les conduisent à intérioriser des conduites professionnelles. …”
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How far back do we need to look to capture diagnoses in electronic health records? A retrospective observational study of hospital electronic health record data by Tom Marshall, Elizabeth Sapey, Miles D Witham, Steve Harris, Rachel Cooper, Chris Plummer, Felicity Evison, James Wason, Heather J Cordell, Suzy Gallier, Fiona E Matthews, Ewan Pearson, Avan A Sayer, Mervyn Singer, Joanne Field, Mohammed Osman, Sian Robinson, Victoria Bartle, Thomas Scharf, Jadene Lewis, Rominique Doal, Peta le Roux, Ray Holding, Paolo Missier

“…This study aimed to ascertain how far back in time electronic hospital records need to be interrogated to capture long-term condition diagnoses.Design Retrospective observational study of routinely collected hospital electronic health record data.Setting Queen Elizabeth Hospital Birmingham (UK)-linked data held by the PIONEER acute care data hub.Participants Patients whose first recorded admission for chronic obstructive pulmonary disease (COPD) exacerbation (n=560) or acute stroke (n=2142) was between January and December 2018 and who had a minimum of 10 years of data prior to the index date.Outcome measures We identified the most common International Classification of Diseases version 10-coded diagnoses received by patients with COPD and acute stroke separately. …”
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Natural killer cells occupy unique spatial neighborhoods in HER2- and HER2+ human breast cancers by Femke A. I. Ehlers, Katie E. Blise, Courtney B. Betts, Shamilene Sivagnanam, Loes F. S. Kooreman, E. Shelley Hwang, Gerard M. J. Bos, Lotte Wieten, Lisa M. Coussens

“…In this study, we developed a multiplex immunohistochemistry (mIHC) antibody panel designed to quantitatively interrogate leukocyte lineages, focusing on NK cells and their phenotypes, in two independent breast cancer patient cohorts (n = 26 and n = 30). …”
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Dynamiques socio-politiques et territorialités de l’immigration ivoirienne en Tunisie by Camille Cassarini

“…In the final section, the article interrogates the way in which these migratory strategies structure the modes of integration of these people in the Tunisian space. …”
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Reflections on the Yoruba Past: Toyin Falola on Isaac Delano by Wale Oyedeji

“…More than many of his contemporaries, Toyin Falola continues to demonstrate that knowledge production from Africa is sustainable if past events are interrogated accordingly. In very many ways, he displays quality content that gives him the sort of image he has built for Africans generally, and himself particularly in the world of intellectualism. …”
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Gardé·es à vue. Domination(s) et reconfigurations des rapports entre manifestant·es et policier·es pendant le hirak (2019-2021) by Lina Benchekor

“…The contrasting emotions aroused by the violence of arrests and interrogations have consequences for the dynamics of engagement and disengagement, sometimes even for other spheres of life, and can constitute a veritable biographical bifurcation. …”
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Characterizing the microstructural transition at the gray matter-white matter interface: Implementation and demonstration of age-associated differences by Joan Y Song, Roman Fleysher, Kenny Ye, Mimi Kim, Molly E Zimmerman, Richard B Lipton, Michael L Lipton

“…This method overcomes techniques issues related to interrogating the GWI. Beyond characterizing normal aging, it could be applied to explore pathological effects at this crucial, yet under-researched region.…”
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Iron deposition is associated with motor and non-motor network breakdown in parkinsonism by Fangda Leng, Yue Gao, Fan Li, Luhua Wei, Yunchuang Sun, Fang Liu, Ying Zhu, Jianxing Qiu, Zhaoxia Wang, Yiwei Zhang

“…The relationship between quantitative iron deposition and brain network status was further interrogated. To further validate the findings, 13 healthy controls and 37 PD patients who had available T1 and rs-fMRI scans were selected from Parkinson’s progression markers initiative (PPMI) database, and network analysis was performed.ResultsIn local cohort, compared to PD, MSA patients showed greater iron deposition in putamen, while PSP patients had greater iron deposition in caudate nucleus and thalamus. …”
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