Development and validation of a model to predict cognitive impairment in traumatic brain injury patients: a prospective observational studyResearch in context by Xiaofang Yuan, Qingrong Xu, Fengxia Du, Xiaoxia Gao, Jing Guo, Jianan Zhang, Yehuan Wu, Zhongkai Zhou, Youjia Yu, Yi Zhang

“…The score was translated into an online risk calculator that is freely available to the public (https://yuanxiaofang.shinyapps.io/Predict_cognitive_impairment_in_TBI/). Interpretation: This model for predicting post-TBI cognitive impairment has potential value for facilitating early predictions by clinicians, aiding the early initiation of preventative interventions for cognitive impairment. …”
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Width evolution of channel belts as a random walk by J. M. Turowski, J. M. Turowski, F. McNab, A. Bufe, A. Bufe, S. Tofelde

“…This result has implications for storage times and chemical alteration of floodplain sediments, as well as the interpretation of measured sediment ages. Model predictions compare well to data of sediment age distributions measured at field sites and the temporal evolution of channel belts observed in flume experiments. …”
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Exemples d’habitats aristocratiques sur les sites des rues Eugène-Desteuque et Ponsardin à Reims/Durocortorum by Magalie Cavé, Stéphane Sindonino, Sabine Groetembril

“…It is, of course, still challenged by the inherent difficulties excavations face in stratified contexts, as well as the consequences of methodical and systematic recovery of building materials at the end of Antiquity, which render reading and interpreting plans of architectural remains difficult. …”
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Identification of positive selection signatures associated with milk and composition traits in Murciano-Granadina and Barki by Hossein Mohammadi, amir hossien khaltabadi farahani, Mohammad Hossein Moradi

“…GeneCards (http://www.genecards.org) and UniProtKB (http://www.uniprot.org) databases were also used to interpret the function of the obtained genes.Results and Discussion Using FST approach, we identified seven genomic regions on chromosomes 4, 6, 14, 15 (two regions per chromosome), 17, and 23 chromosomes. …”
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A Model for Bank Management Performance Appraisal with the Advanced Technologies Approach (Meta-Synthesis Method) by Ehsan Kiani Ghalehno, Habibollah Salarzehi, Bahareh Naseri, Abdolali Keshtegar

“…"Industry 0. 4" or "Fourth Industrial Revolution" is changing our lifestyles and customer-bank relations. It inevitably interprets that both existing commercial techniques and monetary management are not excluded from this change (Singh , 2022). …”
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Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA19... by Liang Qi, Xiang Li, Jiayao Ni, Yali Du, Qing Gu, Baorui Liu, Jian He, Juan Du

“…However, in terms of model interpretability, decision tree methods provide the most intuitive display of the predictive details of the model. …”
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Novel type 2 diabetes prediction score based on traditional risk factors and circulating metabolites: model derivation and validation in two large cohort studiesResearch in context by Ruijie Xie, Christian Herder, Sha Sha, Lei Peng, Hermann Brenner, Ben Schöttker

“…A concise model with 4 instead of 11 metabolites yielded similar results. Interpretation: Adding 11 metabolites to the clinical CDRS led to a novel type 2 diabetes prediction model, we called UK Biobank Diabetes Risk Score (UKB-DRS), substantially outperformed the clinical CDRS. …”
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Conflict-related and sexual trauma in treatment-seeking Arabic-speaking men: a cross-sectional studyResearch in context by Max Vöhringer, Freya Specht, Christine Knaevelsrud, Birgit Wagner, Maria Böttche, Yuriy Nesterko

“…Additionally, the STo group scored greater trauma-related guilt compared to the CRTo (aMD = 0.45, 95% CI [0.29, 0.61], p < 0.001) and the Non-ST/CRT groups (aMD = 0.21, 95% CI [0.33, 0.09], p < 0.001). Interpretation: The results of this exploratory study reveal that a substantial proportion of Arabic-speaking treatment seeking men from different countries in the MENA region reported experiences of sexual and conflict-related trauma, which were associated with high psychological symptom scores. …”
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Global, regional, and national burdens of heart failure in adolescents and young adults aged 10–24 years from 1990 to 2021: an analysis of data from the Global Burden of Disease St... by Chengzhi Yang, Yuhe Jia, Changlin Zhang, Zening Jin, Yue Ma, Xuanye Bi, Aiju Tian

“…The BAPC analysis predicted that the cases of HF prevalence and YLDs would show a rising trend from 2022 to 2030. Interpretation: The burden of HF in adolescents and young adults aged 10–24 years was still increasing globally, which may be obscured by the burden trend of general population. …”
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Alcohol use and HIV suppression after completion of financial incentives for alcohol abstinence and isoniazid adherence: a randomized controlled trialResearch in context by Winnie R. Muyindike, Robin Fatch, Sara Lodi, Nneka I. Emenyonu, Allen Kekibiina, Julian Adong, Brian Beesiga, Kara Marson, Harsha Thirumurthy, Michael G. McDonell, Moses R. Kamya, Gabriel Chamie, Judith A. Hahn

“…Of the 617 participants with 12-month alcohol use measures, alcohol reduction incentives led to a significantly greater proportion with no/low alcohol use at 12-months (20.2% [64/317]) versus no alcohol reduction incentives (11.0% [33/300]); aRD = 8.4%, (95% CI: 3.3–13.4), p = 0.001. Interpretation: Viral suppression was high (>95%) at baseline and at 12 months: we found no effect of either 6-month alcohol reduction or INH adherence incentives on long-term viral suppression. …”
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High risk of asthma among early teens is associated with quantitative differences in mite and cat allergen specific IgE and IgG4: a modified Th2 related antibody response revisited... by Thomas A. Platts-Mills, Behnam Keshavarz, Jeffrey M. Wilson, Sheryl L. Rifas-Shiman, Samuel M. Ailsworth, Joanne E. Sordillo, Lisa Workman, Martin Chapman, Jonas Lidholm, Emily Oken, Diane R. Gold

“…The prevalence and levels of specific IgG4 to these less abundant allergens are significantly lower for Der p 2 and almost absent for Der p 23. Interpretation: High exposure to specific allergens in household dust can enhance production of both sIgE and sIgG4 antibodies, while allergens where abundance is significantly lower in dust can induce sIgE with limited or no sIgG4. …”
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Discussion: acoustic density and ocular structures rigidity in healthy individuals and patients with primary open-angle glaucoma (response to the article by Kazemi A., Zhou B., Zha... by I.N. Koshits, O.V. Svetlova, A.A. Ryabtseva, M.G. Guseva, M.B. Egemberdiev, P.P. Bakshinsky, M.V. Zaseeva

“…However, the traditional interpretation of many clinical findings obtained in practical medicine using high-tech diagnostic equipment is often incorrect and goes against the laws of nature. …”
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Editorial by Jörg Tremmel, Marisa dos Reis, Joseph Burke, Raphaelle Schwarzberg (†)

“…At the institutional level, our current bodies and decision-making processes already have inherent tendencies towards the recognition and protection of future people, for instance the European Convention on Human Rights has been interpreted progressively. Nevertheless, it requires innovative thinking to imagine alternative provisions that can complement today’s legal architecture but revolutionise our restricted thinking on this topic. …”
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Maternal and neonatal complications of pregnant women with bipolar disorder: a systematic review and meta-analysisResearch in context by Damien Etchecopar-Etchart, Masoud Rahmati, Dong Keon Yon, Lee Smith, Laurent Boyer, Guillaume Fond

“…According to the AMSTAR 2 tool, these results correspond to moderate-quality evidence. Interpretation: Despite substantial heterogeneity observed, our findings suggest the presence of a broad spectrum of complications that may affect both pregnant women with bipolar disorder and their newborns. …”
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Multi-cancer early detection tests for general population screening: a systematic literature review by Ros Wade, Sarah Nevitt, Yiwen Liu, Melissa Harden, Claire Khouja, Gary Raine, Rachel Churchill, Sofia Dias

“…Stakeholders contributed to protocol development, report drafting and interpretation of review findings. Results Over 8000 records were identified. …”
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Unveiling neurogenic biomarkers for the differentiation between sepsis patients with or without encephalopathy: an updated meta-analysis by Jiyun Hu, Wenchao Li, Shucai Xie, Ya Liao, Tao Chen, Xinrun Wang, Weiping Xia, Fang Huang, Zhaoxin Qian, Lina Zhang

“…However, results should be interpreted with caution due to the high heterogeneity among studies.…”
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Hybrid versus vaccine immunity of mRNA-1273 among people living with HIV in East and Southern Africa: a prospective cohort analysis from the multicentre CoVPN 3008 (Ubuntu) studyRe... by Nigel Garrett, Asa Tapley, Aaron Hudson, Sufia Dadabhai, Bo Zhang, Nyaradzo M. Mgodi, Jessica Andriesen, Azwidihwi Takalani, Leigh H. Fisher, Jia Jin Kee, Craig A. Magaret, Manuel Villaran, John Hural, Erica Andersen-Nissen, Guido Ferarri, Maurine D. Miner, Bert Le Roux, Eduan Wilkinson, Richard Lessells, Tulio de Oliveira, Jackline Odhiambo, Parth Shah, Laura Polakowski, Margaret Yacovone, Taraz Samandari, Zvavahera Chirenje, Peter James Elyanu, Joseph Makhema, Ethel Kamuti, Harriet Nuwagaba-Biribonwoha, Sharlaa Badal-Faesen, William Brumskine, Soritha Coetzer, Rodney Dawson, Sinead Delany-Moretlwe, Andreas Henri Diacon, Samantha Fry, Katherine Margaret Gill, Zaheer Ahmed Ebrahim Hoosain, Mina C. Hosseinipour, Mubiana Inambao, Craig Innes, Steve Innes, Dishiki Kalonji, Margaret Kasaro, Priya Kassim, Noel Kayange, William Kilembe, Fatima Laher, Moelo Malahleha, Vongane Louisa Maluleke, Grace Mboya, Kirsten McHarry, Essack Mitha, Kathryn Mngadi, Pamela Mda, Tumelo Moloantoa, Cissy Kityo Mutuluuza, Nivashnee Naicker, Vimla Naicker, Anusha Nana, Annet Nanvubya, Maphoshane Nchabeleng, Walter Otieno, Elsje Louise Potgieter, Disebo Potloane, Zelda Punt, Jamil Said, Yashna Singh, Mohammed Siddique Tayob, Yacoob Vahed, Deo Ogema Wabwire, M. Juliana McElrath, James G. Kublin, Linda-Gail Bekker, Peter B. Gilbert, Lawrence Corey, Glenda E. Gray, Yunda Huang, Philip Kotze, Sharlaa Badal-Faesen, Kagisho Baepanye, Veronique Bailey, Katekani Baloyi-Oseh, Mumtaz Booley, Johannes Louis Botha, Yolande Brown, Valerie Brown, Lisa Bunts, Soritha Coetzer, Myron Cohen, Shirley Collie, Rodney Dawson, Pallabi Deb, Hana El Sahly, Jill El-Khorazaty, Andries Engelbrecht, Marianne Gildea, Dhevium Govender, Jen Hanke, Jayla Harris, Simone Hendricks, Nick Hopkinson, Haley Howell, Nzeera Ketter, Kentse Khuto, Faatima Laher Omar, Leolin Katsidzira, Kim Linton, James Ludwig, Bongile Mabilane, Matshidiso Malefo, Ndiitwani Mamushiana, Daciana Margineantu, Jeanine May, Fatima Mayat, Cindy Molitor, Yeshnee Naidoo, Michelle Nebergall, Alan Nguyen, Sarah Nikles, Bianca Noronha, Melissa Peda, Tamara Phiri, Shanthie Pillay, Sureshnee Pillay, Lori Proulx-Burns, Laurie Rinn, Lisa Sanders, Carrie Sopher, Smitha Sripathy, Michael Stirewalt, Houriiyah Tegally, Sara Thiebaud, Alicia Toledano, Stephanie Van Wyk, Shamaya Whitby, Stephany Wilcox, Eduan Wilkinson, Haven Wilvich, Charles Wiysonge, Nelisiwe Xaba, Ntokozo Xulu

“…Twenty PLWH had persistent SARS-CoV-2 virus at least 50 days. Interpretation: Hybrid immunity was associated with superior protection from COVID-19 compared to vaccine immunity with the ancestral mRNA-1273 vaccine. …”
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The graded heat-health risk forecast and early warning with full-season coverage across China: a predicting model development and evaluation studyResearch in context by Qing Wang, Chen Chen, Huaiyue Xu, Yuanyuan Liu, Yu Zhong, Jing Liu, Menghan Wang, Mengxue Zhang, Yiting Liu, Jing Li, Tiantian Li

“…It was estimated that the proper implementation of the HHSEW-based early warning system would save 220 billion CNY in heat-related health burden compared to the current heatwave early-warning system. Interpretation: The HHSEW model has been proven to surpass the current heatwave early warning system. …”
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Effectiveness of a universal film intervention in reducing violence against children and increasing positive parenting among migrant and displaced caregivers from Myanmar: a commun... by Amanda Sim, Khaing Zar Lwin, Stephanie Eagling-Peche, G.J. Melendez-Torres, Seema Vyas, Francisco Calderon, Tawanchai Jirapramukpitak, Jamie Lachman, Sureeporn Punpuing, Andrea Gonzalez, Mary Soan, Nway Nway Oo, Ivet Castello Mitjans, Greg Tyrosvoutis, Eve Puffer

“…There were no reported adverse effects. Interpretation: Universal parenting interventions using a film-based entertainment-education approach can effectively reduce physical violence against children and increase positive parenting, with potential for scalability in low-resource settings. …”
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homeRNA self-blood collection enables high-frequency temporal profiling of presymptomatic host immune kinetics to respiratory viral infection: a prospective cohort studyResearch in... by Fang Yun Lim, Hannah G. Lea, Ashley M. Dostie, Soo-Young Kim, Tammi L. van Neel, Grant W. Hassan, Meg G. Takezawa, Lea M. Starita, Karen N. Adams, Michael Boeckh, Joshua T. Schiffer, Ollivier Hyrien, Alpana Waghmare, Erwin Berthier, Ashleigh B. Theberge

“…Finally, elevated baseline expression of antimicrobial peptides was observed in exposed-uninfected individuals. Interpretation: We demonstrated that unsupervised self-collection and stabilization of capillary blood can be applied to natural infection studies to characterize detailed early host immune kinetics at a temporal resolution comparable to that of human challenge studies. …”
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