Modelling the epidemiological and economic impact of digital adherence technologies with differentiated care for tuberculosis treatment in Ethiopia by Richard White, Katherine L Fielding, Salome Charalambous, Nicola Foster, Degu Jerene, Andrew Mganga, Taye Letta, Job van Rest, Amare Worku Tadesse, Rein MGJ Houben, Ahmed Bedru, Kristian van Kalmthout, Christopher Finn McQuaid, Lara Goscé, Jense van der Wal, Martin J Harker, Norma Madden, Tofik Abdurhman, Demekech Gadissa, Tanyaradzwa N Dube, Jason Alacapa, Natasha Deyanova

“…The maximum possible epidemiological impact a theoretical DAT intervention could achieve over the same timescale would be a 3% (95% UI 1.4%; 5.5%) reduction in incident TB and an 8.2% (95% UI 4.4%; 12.8%) reduction in TB deaths.Interpretation DAT interventions, while showing limited epidemiological impact, could substantially reduce TB treatment costs for both patients and the healthcare provider.…”
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Discovery and Spectroscopic Confirmation of Aquarius III: A Low-mass Milky Way Satellite Galaxy by W. Cerny, A. Chiti, M. Geha, B. Mutlu-Pakdil, A. Drlica-Wagner, C. Y. Tan, M. Adamów, A. B. Pace, J. D. Simon, D. J. Sand, A. P. Ji, T. S. Li, A. K. Vivas, E. F. Bell, J. L. Carlin, J. A. Carballo-Bello, A. Chaturvedi, Y. Choi, A. Doliva-Dolinsky, O. Y. Gnedin, G. Limberg, C. E. Martínez-Vázquez, S. Mau, G. E. Medina, M. Navabi, N. E. D. Noël, V. M. Placco, A. H. Riley, I. U. Roederer, G. S. Stringfellow, C. R. Bom, P. S. Ferguson, D. J. James, D. Martínez-Delgado, P. Massana, D. L. Nidever, J. D. Sakowska, L. Santana-Silva, N. F. Sherman, E. J. Tollerud, DELVE Collaboration

“…Based on calcium-triplet metallicities of the six brightest red giant members, we find that Aquarius III is very metal-poor ([Fe/H]= − 2.61 ± 0.21) with a statistically significant metallicity spread ( ${\sigma }_{[\mathrm{Fe}/{\rm{H}}]}={0.46}_{-0.14}^{+0.26}$ dex). We interpret this metallicity spread as strong evidence that the system is a dwarf galaxy as opposed to a star cluster. …”
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Modeling the tropical fish community related to land uses and environmental determinants by N. Takarina, O. Chuan, M. Afifudin, L. Tristan, I. Arif, A. Adiwibowo

“…Land uses at the sites were interpreted using satellite imagery. Fish diversity was determined using the Shannon–Wiener index, rarefaction curve, and Lorenz graph. …”
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Pharmacological management of gambling disorder: A systematic review and network meta-analysis by Konstantinos Ioannidis, Cinzia Del Giovane, Charidimos Tzagarakis, Jeremy E. Solly, Samuel J. Westwood, Valeria Parlatini, Henrietta Bowden-Jones, Jon E. Grant, Samuele Cortese, Samuel R. Chamberlain

“…Nalmefene [Odds Ratio (OR): 7.55; 95 %CI: (2.24–25.41)] and naltrexone (OR: 7.82; 95 %CI: (1.26–48.70)) had significantly higher dropout due to side effects (lower tolerability) compared with placebo. Interpretation: Based on NMA, nalmefene and naltrexone currently have the most supportive evidence for the pharmacological treatment of gambling disorder. …”
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Solid and Gaseous Methane in IRAS 23385+6053 as Seen with Open JWST Data by Ruslan Nakibov, Varvara Karteyeva, Igor Petrashkevich, Maksim Ozhiganov, Mikhail Medvedev, Anton Vasyunin

“…The band at 7.58–7.8 μ m (1320–1280 cm ^−1 ) is interpreted as a wide solid absorption methane feature overlapped by the sharp features of the methane emission. …”
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Analytical Accuracy of a Continuous Glucose Monitor in Adult Diabetic KetoacidosisTake-Home Points by Nathan L. Haas, MD, Lynn Ang, MD, Nazanene H. Esfandiari, MD, Ahsan M. Khan, MBBS, James A. Cranford, PhD, Ashley Cohen, MD, Jordan Sell, MD, Mostafa Abdel-Hamid, MD, Kevin E. Romanchik, BSN, RN, Frederick K. Korley, MD, PhD

“…The first incidence of glucose < 150 mg/dL (n = 14) was detected 28.9 minutes earlier by CGM than POCBG measurements. Interpretation: In this study, CGM provided accurate measurements of blood glucose and identified missed opportunities for earlier intervention in adults with DKA. …”
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A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in... by Thomas R. Moench, Lakshmi Botta, Brian Farrer, Jason D. Lickliter, Hyunah Kang, Yoona Park, Cheolmin Kim, Marshall Hoke, Miles Brennan, Morgan D. McSweeney, Zachary Richardson, John B. Whelan, Jong Moon Cho, Soo Young Lee, Frances Faurot, Jeff Hutchins, Samuel K. Lai

“…Geometric mean serum levels in the multiple dose cohort peaked at 0.51 μg/mL 3 days after the final dose. Interpretation: IN-006 was well-tolerated and achieved concentrations in the respiratory tract orders of magnitude above the IC50 range typical of antiviral mAbs. …”
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Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadthResearch in context by Katrina M. Pollock, Hannah M. Cheeseman, Leon R. McFarlane, Suzanne Day, Monica Tolazzi, Hannah L. Turner, Jennifer Joypooranachandran, Katsiaryna Shramko, Stefania Dispinseri, Philipp Mundsperger, Ilja Bontjer, Nana-Marie Lemm, Sofia Coelho, Maniola Tanaka, Tom Cole, Bette Korber, Dietmar Katinger, Quentin J. Sattentau, Andrew B. Ward, Gabriella Scarlatti, Rogier W. Sanders, Robin J. Shattock

“…Neutralising antibody function correlated with binding to V1/V3 and V5 epitopes and peaked after the third injection. Interpretation: Rationally designed prefusion-stabilised native-like Env trimers are robustly immunogenic in a prime-boost schedule. …”
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The influence of post-processing methods and frequency bands on rs-fMRI: An example of electroacupuncture at Zusanli (ST36) by YingJie Kang, YiLei Chen, ZhiGang Gong, YanWen Huang, Hui Wang, Jiling Huang, SongHua Zhan, YiJing Li, WenLi Tan

“…Conclusion: Post-processing methods affect the interpretation of brain effects caused by electroacupuncture at ST36. …”
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Psychoeducation of higher education seekers with using of the resource-oriented model of stress resiliency in war conditions by V.V. Ogorenko, A.E. Nikolenko, T.Y. Shusterman, V.O. Kokashynskyi, A.B. Khotimska, M.H. Koren

“…During psychoeducational work with higher education seekers, their resiliency models were analyzed, interpreted, and balanced. Study results should be taken into account in psychological support efforts for higher education seekers in war and post-war time.…”
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Planetary health education in undergraduate medical education in Germany: results from structured interviews and an online survey within the national PlanetMedEd Project by Fabio Grieco, Sandra Parisi, Anne Simmenroth, Michael Eichinger, Michael Eichinger, Janina Zirkel, Janina Zirkel, Sarah König, Jana Jünger, Jana Jünger, Eva Geck, Eva-Maria Schwienhorst-Stich

“…In contrast to mandatory educational activities, student involvement was reported for the majority of electives and was significantly associated with transformative learning objectives.InterpretationDespite a steady rise in teaching activities, mandatory Planetary Health Education remains insufficiently integrated into undergraduate medical education in Germany. …”
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Adrenal aldosterone synthase (CYP11B2) histopathology and its association with disease-induced sudden death: a cross-sectional studyResearch in context by Antero Ylänen, Juhani Isojärvi, Antti Virtanen, Helena Leijon, Tiina Vesterinen, Aapo L. Aro, Heini Huhtala, Eeva Kokko, Ilkka Pörsti, Marianna Viukari, Pasi I. Nevalainen, Niina Matikainen

“…Other findings included two pheochromocytomas, one bilateral adrenal metastasis, and two unilateral adrenal metastases. Interpretation: In this exploratory study, APA or APN were more frequently seen in DSD and SCD than nDSD cases. …”
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Effect of Acupuncture Stimulation of Hegu (LI4) and Taichong (LR3) on the Resting-State Networks in Alzheimer’s Disease: Beyond the Default Mode Network by Shaozhen Ji, Hao Zhang, Wen Qin, Ming Liu, Weimin Zheng, Ying Han, Haiqing Song, Kuncheng Li, Jie Lu, Zhiqun Wang

“…These findings might have some reference values for the interpretation of the combination stimulus of Hegu (LI4) and Taichong (LR3) in AD patients, which could deepen our understanding of the potential mechanisms of acupuncture on AD.…”
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Creep enhancement and sliding in a temperate, hard-bedded alpine glacier by J.-P. Roldán-Blasco, A. Gilbert, L. Piard, F. Gimbert, C. Vincent, O. Gagliardini, A. Togaibekov, A. Togaibekov, A. Walpersdorf, N. Maier

“…We demonstrate that the observed deformation rate profile has limited sensitivity to the flow law exponent (<span class="inline-formula"><i>n</i></span>) and instead mainly reflects an increase in the creep factor (<span class="inline-formula"><i>A</i></span>) with depth, with <span class="inline-formula"><i>A</i></span> departing from its surface value by up to a factor of 2.5 below 160 m depth. We interpret this creep factor enhancement as an effect of increasing interstitial water content with depth (from 0 % to 1.3 %), which results in an average value of <span class="inline-formula"><i>A</i>=148</span> MPa<span class="inline-formula">⁻³</span> a<span class="inline-formula">⁻¹</span>. …”
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Long-term trends in the prevalence of cardiovascular-kidney-metabolic syndrome in South Korea, 2011–2021: a representative longitudinal serial studyResearch in context by Yesol Yim, Jae E. Lee, Yejun Son, Soeun Kim, Hojae Lee, Sooji Lee, Wonwoo Jang, Hanseul Cho, Hayeon Lee, Kyeongmin Lee, Hyesu Jo, Jaeyu Park, Jiyeon Oh, Louis Jacob, Jiseung Kang, Hyunji Sang, Sang Youl Rhee, Dong Keon Yon

“…Advanced stages were more common among vulnerable subgroups, including males, older adults, rural residents, smokers, drinkers, individuals with obesity, lower education levels, and lower household incomes. Interpretation: This is the first study to investigate the long-term prevalence of CKM syndrome based on stages at the national level in an Asian population. …”
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Repeated social defeat in male mice induced unique RNA profiles in projection neurons from the amygdala to the hippocampus by Rebecca G. Biltz, Wenyuan Yin, Ethan J. Goodman, Lynde M. Wangler, Amara C. Davis, Braedan T. Oliver, Jonathan P. Godbout, John F. Sheridan

“…For instance, neurons in the prefrontal cortex, amygdala, and hippocampus are involved in the interpretation of and response to fear and threatful stimuli after RSD. …”
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MUC5B modulation of early oral biofilm glucose metabolism by Carolina Robertsson, Carolina Robertsson, Julia Davies, Gunnel Svensäter, Anders Bay Nord, Niclas Norrström, Claes Wickström

“…IntroductionSalivary mucin MUC5B has been suggested to support eubiosis in early oral biofilms by regulating the attachment of commensals, while downregulating dysbiotic activities related to dental caries development, such as microbial carbohydrate transport and metabolism.MethodsTo investigate how the metabolism of glucose, a potential driver for dental caries, in early mono- and dual-species biofilms of oral Actinomyces naeslundii and Streptococcus gordonii clinical isolates was affected by the presence of the complex salivary mucin MUC5B, this study employed nuclear magnetic resonance (NMR)-based metabolomics with the interpretation of network integration.Results and discussionMUC5B reduced early attachment in the presence of glucose compared with uncoated surfaces but maintained even species distribution. …”
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"ANAPUS KANTO": M. FOUCAULT NAUJOJI MORALĖS GENEALOGIJA by Jūratė Baranova

“…Besides that, the Antikantianism of Foucault stems from the interpretation of relation between power and subject following Nietzschean genealogy. …”
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ANTHROPOLOGICAL PROBLEMS IN THE PHILOSOPHICAL WORKS OF RUSSIAN SPIRITUAL ACADEMIES’ TEACHERS OF THE EARLY 20TH CENTURY by M. A. Ershova

“…Archimandrite Sergious (Stragorodsky) interprets the topic of finding salvation not against the background of the changes in God, but from the standpoint of the changes that occur in humanity. …”
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Neural tube defects in a war-torn Tigray regional state of Ethiopia: a retrospective study of 54,626 deliveries by Birhane Alem Berihu, Afework Mulugeta, Tony Magana, Masresha Tessema, Tafere Gebreegziabher, Yibrah Berhe, Abadi Leul Welderufael, Hayelom Kebede Mekonen

“…The results were systematically presented in both textual, tabular, graph formats to facilitate understanding and interpretation. Results Out of 54,626 delivery records, 1,612 cases of NTDs were identified (1,434 NTD cases and 178 isolated hydrocephalus cases). …”
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