The value-added model of the supply chain of petrochemical industries with a sustainable development approach by ali amiri, seyed abbas heydari, vahidreza Mirabi

“…These components were leveled based on interpretive structural technique, and they formed a model in 7 levels. …”
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Global burden of metabolic dysfunction-associated steatotic liver disease, 2010 to 2021 by Gong Feng, Giovanni Targher, Christopher D. Byrne, Yusuf Yilmaz, Vincent Wai-Sun Wong, Cosmas Rinaldi Adithya Lesmana, Leon A. Adams, Jerome Boursier, George Papatheodoridis, Mohamed El-Kassas, Nahum Méndez-Sánchez, Silvia Sookoian, Laurent Castera, Wah-Kheong Chan, Feng Ye, Sombat Treeprasertsuk, Helena Cortez-Pinto, Hon Ho Yu, Won Kim, Manuel Romero-Gómez, Atsushi Nakajima, Khin Maung Win, Seung Up Kim, Adriaan G. Holleboom, Giada Sebastiani, Ponsiano Ocama, John D. Ryan, Monica Lupșor-Platon, Hasmik Ghazinyan, Mamun Al-Mahtab, Saeed Hamid, Nilanka Perera, Khalid A. Alswat, Qiuwei Pan, Michelle T. Long, Vasily Isakov, Man Mi, Marco Arrese, Arun J. Sanyal, Shiv Kumar Sarin, Nathalie Carvalho Leite, Luca Valenti, Philip N. Newsome, Hannes Hagström, Salvatore Petta, Hannele Yki-Järvinen, Jörn M. Schattenberg, Marlen I. Castellanos Fernández, Isabelle A. Leclercq, Gulnara Aghayeva, Abdel-Naser Elzouki, Ali Tumi, Ala I. Sharara, Asma Labidi, Faisal M. Sanai, Khaled Matar, Maen Al-Mattooq, Maisam Waid Akroush, Mustapha Benazzouz, Nabil Debzi, Maryam Alkhatry, Salma Barakat, Said A. Al-Busafi, John Rwegasha, Wah Yang, Agyei Adwoa, Christopher Kenneth Opio, Mohammadjavad Sotoudeheian, Yu Jun Wong, Jacob George, Ming-Hua Zheng

“…However, the study’s reliance on modeling and available data suggests cautious interpretation, and further research is needed to validate these findings in clinical and real-world settings.…”
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A novel ddPCR™ assay for eDNA detection and quantification of Greater Amberjack Seriola dumerilli and three congeners in US waters: challenges and application to fisheries independ... by P. Joana Dias, Ryan Lehman, Bryan L. Huerta-Beltrán, Ana Wheeler, Crystal L. Hightower, Jessica Heise, Theodore Switzer, Clint Rhode, J. Marcus Drymon, Lynne Stokes, Mark A. Albins, Sean Powers, Nicole Phillips

“…Key to progressing the field is Droplet Digital™ PCR (ddPCR™), a highly sensitive technique with advanced multiplexing and direct quantification capabilities that can provide fisheries scientists with improved interpretation of eDNA data. Methods We developed and validated a novel tetraplex ddPCR™ assay able to detect and distinguish between S. dumerili, S. fasciata, S. rivoliana, and S. zonata from seawater eDNA samples. …”
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Evolving trends in lung cancer risk factors in the ten most populous countries: an analysis of data from the 2019 Global Burden of Disease StudyResearch in context by Chinmay T. Jani, Samuel A. Kareff, Dan Morgenstern-Kaplan, Ana S. Salazar, Georgina Hanbury, Justin D. Salciccioli, Dominic C. Marshall, Joseph Shalhoub, Harpreet Singh, Estelamari Rodriguez, Gilberto Lopes

“…Despite a decline in asbestos-associated TBL cancer ASMR from 8.91/100,000 to 6.0/100,000, the rate in the United States remained twice higher than the global average for the entire study period. Interpretation: Tobacco-associated TBL cancer mortality is declining but still predominant. …”
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Association of clinical signs of possible serious bacterial infections identified by community health workers with mortality of young infants in South Asia: a prospective, observat... by Gary L. Darmstadt, Saifuddin Ahmed, Mohammad Shahidul Islam, Safa Abdalla, Shams El Arifeen, Melissa L. Arvay, Abdullah H. Baqui, Zulfiqar A. Bhutta, Anuradha Bose, Nicholas E. Connor, Belal Hossain, Rita Isaac, Arif Mahmud, Dipak K. Mitra, Luke C. Mullany, Imran Nisar, Kalpana Panigrahi, Pinaki Panigrahi, Qazi Sadeq-ur Rahman, Senjuti Saha, Sajid B. Soofi, Nardos Solomon, Mathuram Santosham, Stephanie J. Schrag, Shamim A. Qazi, Samir K. Saha

“…Hypothermia had particularly high risk for mortality during days 7–<60 (HR 45.1, 95% CI 27.6–73.4). Interpretation: WHO reconsideration of hypothermia as a sign of critical illness is warranted. …”
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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context by Podjanee Jittamala, Simon Boyd, William H.K. Schilling, James A. Watson, Thundon Ngamprasertchai, Tanaya Siripoon, Viravarn Luvira, Elizabeth M. Batty, Phrutsamon Wongnak, Lisia M. Esper, Pedro J. Almeida, Cintia Cruz, Fernando R. Ascencao, Renato S. Aguiar, Najia K. Ghanchi, James J. Callery, Shivani Singh, Varaporn Kruabkontho, Thatsanun Ngernseng, Jaruwan Tubprasert, Wanassanan Madmanee, Kanokon Suwannasin, Amornrat Promsongsil, Borimas Hanboonkunupakarn, Kittiyod Poovorawan, Manus Potaporn, Attasit Srisubat, Bootsakorn Loharjun, Walter R.J. Taylor, Farah Qamar, Abdul Momin Kazi, M. Asim Beg, Danoy Chommanam, Sisouphanh Vidhamaly, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Arjen M. Dondorp, Nicholas P.J. Day, Mauro M. Teixeira, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Nicholas J. White

“…Fluoxetine was well tolerated, there were no serious adverse events and only one grade 3 adverse event in the intervention arm. Interpretation: Overall, the evidence from this study is compatible with fluoxetine having a weak in vivo antiviral activity against SARS-CoV-2, although the primary endpoint is also compatible with no effect. …”
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Risk of aortic aneurysm or dissection following use of fluoroquinolones: a retrospective multinational network cohort studyResearch in context by Jack L. Janetzki, Jung Ho Kim, Evan Minty, Jung Ah Lee, Daniel R. Morales, Rohan Khera, Chungsoo Kim, Thamir M. Alshammari, Scott L. DuVall, Michael E. Matheny, Thomas Falconer, Seonji Kim, Thanh-Phuc Phan, Phung-Anh Nguyen, Min-Huei Hsu, Jason C. Hsu, Rae Woong Park, Kenneth K.C. Man, Sarah Seager, Mui Van Zandt, James P. Gilbert, Patrick B. Ryan, Martijn J. Schuemie, Marc A. Suchard, George Hripcsak, Nicole Pratt, Seng Chan You

“…There was no significant difference in risk for FQ versus CPH (ARD, 0.11 per 1000 person-year; calibrated HR, 1.01 [95% CI 0.82–1.25]). Interpretation: This large-scale study used a rigorous design with objective diagnostics to address bias and confounding. …”
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Coal mining-induced composite damage to geological bodies and geological guarantee against damage reduction by Shuangming WANG, Qiang SUN, Xin HU, Jishi GENG, Enke HOU, Shengquan WANG, Shutao ZHOU, Qingmin SHI, Shihao YUAN, Kai CHEN, Shijie SONG

“…., a precise exploration system, an intelligent perception system, a rapid interpretation system, a risk assessment system, an engineering loss reduction system, and a comprehensive analysis platform for mining-induced composite damage. …”
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Prevalence and determinants of post-neonatal mortality in East Africa: a multilevel analysis of the recent demographic and health survey by Alebachew Ferede Zegeye, Desale Bihonegn Asmamaw, Wubshet D. Negash, Wubshet D. Negash, Tadele Biresaw Belachew, Elsa Awoke Fentie, Atitegeb Abera Kidie, Tsegaw Amare Baykeda, Samrawit Mihret Fetene, Banchlay Addis, Sisay Maru Wubante, Abel Endawkie, Tadesse Tarik Tamir

“…In the multilevel logistic regression model, significant factors were deemed to be associated with post-neonatal mortality at p-values &lt;0.05. The data were interpreted using the adjusted odds ratio (AOR) and confidence interval (CI). …”
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Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context by Thuy-Dung Nguyen, Joeri J. Meijsen, Robert Sigström, Ralf Kuja-Halkola, Ying Xiong, Arvid Harder, Kaarina Kowalec, Joëlle A. Pasman, Carolina Scarpa, Elin Hörbeck, Lina Jonsson, Sara Hägg, Niamh Mullins, Kevin S. O’Connell, Christina Dalman, Dorte Helenius, Richard Zetterberg, Henrik Larsson, Paul Lichtenstein, Ole A. Andreassen, Thomas Werge, Alfonso Buil, Mikael Landén, Patrick F. Sullivan, Yi Lu

“…PRS for BD type-I was associated with increased odds of psychotic MDD, while BD type-II PRS showed no significant association with psychotic MDD. Interpretation: This study provides evidence for the genetic basis of psychotic MDD, underscoring its unique position bridging the spectrum of mood and psychotic disorders. …”
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Outcomes of endometrial cancer prevention strategies in patients with Lynch syndrome: a nationwide cohort study in the NetherlandsResearch in context by Ellis L. Eikenboom, Lotte van Leeuwen, Floris Groenendijk, Jorien M. Woolderink, Anne M. Van Altena, Monique E. Van Leerdam, Manon C.W. Spaander, Helena C. van Doorn, Anja Wagner, M.C. Breijer, A.S. Tjalsma, F. Vork, H.P.M. Smedts, J. van der Velden, M.M.A. Brood-van Zanten, J.E. van de Riet, A.L.M. Oei, H. Kessel, P.M.L.H. Vencken, M.P.L.M. Snijders, R.H.M. Hermans, A. Bouman, H.W. Ünsalan, A.M.G. van de Swaluw, G.M. Plaisier, H.C. van Doorn, K. van den Berg, W. Hofhuis, Y.A.J.M. Dabekausen, P.R. Kolk, H.T.C. Nagel, A.M.L.D. van Haaften-de Jong, A.C. van Hof, M. van den Hende, J. Kaijser, H.H. de Haan, R.A. Smit, M.W.G. Moonen-Delarue, J.J. Beltman, J.E. Martens, R. Kruitwagen, J.M. van der Ploeg, J.M. Woolderink, S.F.P.J. Coppus, M.J. Duk, M.J.A. Apperloo, C.M. Koopmans, C.C.M. Buis, H. van Meurs, E.C. Dul, B.B.J. Hermsen, A.M. van Altena, A. Baalbergen, A.A. van Ginkel-Terng, M. Baas, P. van Greunen, C.M.W.H. Smeets, H. Knipscheer, J.E. Martens, C. Schmeink, M.D. van der Laan, E.J.M. van Es, J.E.W. van Dijk, F.M.F. Rosier-van Dunné, H. Nijman, C.G. Gerestein, D. Boskamp, E.C.A.H. Scheers, M. Verbruggen, L.R. Bartelink, C.B.M. Kruijdenberg, J.M. Briët, B. Visschers, M. Engelen

“…For all endometrial carcinomas together, including index carriers, cumulative incidence was 22.7% at age 70. Interpretation: In a nation-wide cohort of Lynch syndrome carriers, nearly one-third of eligible carriers did not undergo gynaecological surveillance. …”
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Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysisResearch in context by Anis Rassi, Jr, Alyssa Grimshaw, Ashwin Sarwal, Ranjit Sah, Sangam Shah, Nelson I. Agudelo Higuita, Fabio Mahamed Rassi, Michaele Francesco Corbisiero, Hannah M. Kyllo, Jordan Stellern, Samantha Kaplan, Luis A. Marcos, Edgar A. Ramírez-García, Martin Casapia, Peter Hotez, Maria Elena Bottazzi, Shital Patel, Carlos Franco-Paredes, José Antonio Marin-Neto, Andrés F. Henao-Martínez

“…Compared to no treatment or placebo, antiparasitic treatment led to a reduction in i) ECG changes (17 studies, 4994 participants: risk ratio (RR): 0.48, 95% CI 0.36–0.66, p < 0.001; I2 = 76.4%) with a number needed to treat (NNT) of 5; ii) disease progression (12 studies, 5722 participants: RR: 0.35, 95% CI 0.23–0.51, p < 0.001; I2 = 72.4%) NNT of 6; iii) cardiovascular death (7 studies, 5662 participants: RR: 0.44, 95% CI 0.21–0.95, p = 0.04; I2 = 50.5%) NNT of 22; and iv) overall mortality (10 studies, 7694 participants: RR: 0.54, 95% CI 0.34–0.87, p < 0.001; I2 = 60%) NNT of 23. Interpretation: We found compelling evidence that antiparasitic treatment significantly reduces the risk of ECG changes, disease progression, cardiovascular death, and overall mortality in chronic Chagas disease. …”
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Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context by Wenqian Liu, Mo Yang, Nanxing Wang, Xiangrong Liu, Chaoyu Wang, Kaibin Shi, Fu-Dong Shi, Yuesong Pan, Mingjun Zhang, Zhiwei Sun, Yongjun Wang, Yilong Wang

“…In the treatment of stroke with neuroprotective agents, although the drug dosage of ICO injection was lower than intravenous injection, drug accumulation in the brain increased after ICO injection, which helped repair nerve damage, reduce neuronal apoptosis, and decrease the expression of inflammatory factors. Interpretation: ICO injection is a central nervous system drug delivery method that utilizes natural microchannels between the skull and dura mater for efficient drug delivery. …”
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Prediction model for type 2 diabetes mellitus and its association with mortality using machine learning in three independent cohorts from South Korea, Japan, and the UK: a model de... by Hayeon Lee, Seung Ha Hwang, Seoyoung Park, Yunjeong Choi, Sooji Lee, Jaeyu Park, Yejun Son, Hyeon Jin Kim, Soeun Kim, Jiyeon Oh, Lee Smith, Damiano Pizzol, Sang Youl Rhee, Hyunji Sang, Jinseok Lee, Dong Keon Yon

“…Similar patterns and trends were observed in the validation cohorts (T1: 1.74 [1.49–2.03], T2: 1.97 [1.69–2.30], and T3: 3.31 [2.82–3.38] in validation cohort A; T1: 1.33 [1.03–1.71], T2: 1.54 [1.21–1.96], and T3: 1.73 [1.36–2.20] in validation cohort B). Interpretation: This study derived and validated an ML-based model to predict the incidence of T2DM within 5 years across three countries (South Korea, Japan, and the UK), showing that the model probability is associated with an increased risk of mortality. …”
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Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology by Elliot Gould, Hannah S. Fraser, Timothy H. Parker, Shinichi Nakagawa, Simon C. Griffith, Peter A. Vesk, Fiona Fidler, Daniel G. Hamilton, Robin N. Abbey-Lee, Jessica K. Abbott, Luis A. Aguirre, Carles Alcaraz, Irith Aloni, Drew Altschul, Kunal Arekar, Jeff W. Atkins, Joe Atkinson, Christopher M. Baker, Meghan Barrett, Kristian Bell, Suleiman Kehinde Bello, Iván Beltrán, Bernd J. Berauer, Michael Grant Bertram, Peter D. Billman, Charlie K. Blake, Shannon Blake, Louis Bliard, Andrea Bonisoli-Alquati, Timothée Bonnet, Camille Nina Marion Bordes, Aneesh P. H. Bose, Thomas Botterill-James, Melissa Anna Boyd, Sarah A. Boyle, Tom Bradfer-Lawrence, Jennifer Bradham, Jack A. Brand, Martin I. Brengdahl, Martin Bulla, Luc Bussière, Ettore Camerlenghi, Sara E. Campbell, Leonardo L. F. Campos, Anthony Caravaggi, Pedro Cardoso, Charles J. W. Carroll, Therese A. Catanach, Xuan Chen, Heung Ying Janet Chik, Emily Sarah Choy, Alec Philip Christie, Angela Chuang, Amanda J. Chunco, Bethany L. Clark, Andrea Contina, Garth A. Covernton, Murray P. Cox, Kimberly A. Cressman, Marco Crotti, Connor Davidson Crouch, Pietro B. D’Amelio, Alexandra Allison de Sousa, Timm Fabian Döbert, Ralph Dobler, Adam J. Dobson, Tim S. Doherty, Szymon Marian Drobniak, Alexandra Grace Duffy, Alison B. Duncan, Robert P. Dunn, Jamie Dunning, Trishna Dutta, Luke Eberhart-Hertel, Jared Alan Elmore, Mahmoud Medhat Elsherif, Holly M. English, David C. Ensminger, Ulrich Rainer Ernst, Stephen M. Ferguson, Esteban Fernandez-Juricic, Thalita Ferreira-Arruda, John Fieberg, Elizabeth A. Finch, Evan A. Fiorenza, David N. Fisher, Amélie Fontaine, Wolfgang Forstmeier, Yoan Fourcade, Graham S. Frank, Cathryn A. Freund, Eduardo Fuentes-Lillo, Sara L. Gandy, Dustin G. Gannon, Ana I. García-Cervigón, Alexis C. Garretson, Xuezhen Ge, William L. Geary, Charly Géron, Marc Gilles, Antje Girndt, Daniel Gliksman, Harrison B. Goldspiel, Dylan G. E. Gomes, Megan Kate Good, Sarah C. Goslee, J. Stephen Gosnell, Eliza M. Grames, Paolo Gratton, Nicholas M. Grebe, Skye M. Greenler, Maaike Griffioen, Daniel M. Griffith, Frances J. Griffith, Jake J. Grossman, Ali Güncan, Stef Haesen, James G. Hagan, Heather A. Hager, Jonathan Philo Harris, Natasha Dean Harrison, Sarah Syedia Hasnain, Justin Chase Havird, Andrew J. Heaton, María Laura Herrera-Chaustre, Tanner J. Howard, Bin-Yan Hsu, Fabiola Iannarilli, Esperanza C. Iranzo, Erik N. K. Iverson, Saheed Olaide Jimoh, Douglas H. Johnson, Martin Johnsson, Jesse Jorna, Tommaso Jucker, Martin Jung, Ineta Kačergytė, Oliver Kaltz, Alison Ke, Clint D. Kelly, Katharine Keogan, Friedrich Wolfgang Keppeler, Alexander K. Killion, Dongmin Kim, David P. Kochan, Peter Korsten, Shan Kothari, Jonas Kuppler, Jillian M. Kusch, Malgorzata Lagisz, Kristen Marianne Lalla, Daniel J. Larkin, Courtney L. Larson, Katherine S. Lauck, M. Elise Lauterbur, Alan Law, Don-Jean Léandri-Breton, Jonas J. Lembrechts, Kiara L’Herpiniere, Eva J. P. Lievens, Daniela Oliveira de Lima, Shane Lindsay, Martin Luquet, Ross MacLeod, Kirsty H. Macphie, Kit Magellan, Magdalena M. Mair, Lisa E. Malm, Stefano Mammola, Caitlin P. Mandeville, Michael Manhart, Laura Milena Manrique-Garzon, Elina Mäntylä, Philippe Marchand, Benjamin Michael Marshall, Charles A. Martin, Dominic Andreas Martin, Jake Mitchell Martin, April Robin Martinig, Erin S. McCallum, Mark McCauley, Sabrina M. McNew, Scott J. Meiners, Thomas Merkling, Marcus Michelangeli, Maria Moiron, Bruno Moreira, Jennifer Mortensen, Benjamin Mos, Taofeek Olatunbosun Muraina, Penelope Wrenn Murphy, Luca Nelli, Petri Niemelä, Josh Nightingale, Gustav Nilsonne, Sergio Nolazco, Sabine S. Nooten, Jessie Lanterman Novotny, Agnes Birgitta Olin, Chris L. Organ, Kate L. Ostevik, Facundo Xavier Palacio, Matthieu Paquet, Darren James Parker, David J. Pascall, Valerie J. Pasquarella, John Harold Paterson, Ana Payo-Payo, Karen Marie Pedersen, Grégoire Perez, Kayla I. Perry, Patrice Pottier, Michael J. Proulx, Raphaël Proulx, Jessica L Pruett, Veronarindra Ramananjato, Finaritra Tolotra Randimbiarison, Onja H. Razafindratsima, Diana J. Rennison, Federico Riva, Sepand Riyahi, Michael James Roast, Felipe Pereira Rocha, Dominique G. Roche, Cristian Román-Palacios, Michael S. Rosenberg, Jessica Ross, Freya E. Rowland, Deusdedith Rugemalila, Avery L. Russell, Suvi Ruuskanen, Patrick Saccone, Asaf Sadeh, Stephen M. Salazar, Kris Sales, Pablo Salmón, Alfredo Sánchez-Tójar, Leticia Pereira Santos, Francesca Santostefano, Hayden T. Schilling, Marcus Schmidt, Tim Schmoll, Adam C. Schneider, Allie E. Schrock, Julia Schroeder, Nicolas Schtickzelle, Nick L. Schultz, Drew A. Scott, Michael Peter Scroggie, Julie Teresa Shapiro, Nitika Sharma, Caroline L. Shearer, Diego Simón, Michael I. Sitvarin, Fabrício Luiz Skupien, Heather Lea Slinn, Grania Polly Smith, Jeremy A. Smith, Rahel Sollmann, Kaitlin Stack Whitney, Shannon Michael Still, Erica F. Stuber, Guy F. Sutton, Ben Swallow, Conor Claverie Taff, Elina Takola, Andrew J. Tanentzap, Rocío Tarjuelo, Richard J. Telford, Christopher J. Thawley, Hugo Thierry, Jacqueline Thomson, Svenja Tidau, Emily M. Tompkins, Claire Marie Tortorelli, Andrew Trlica, Biz R. Turnell, Lara Urban, Stijn Van de Vondel, Jessica Eva Megan van der Wal, Jens Van Eeckhoven, Francis van Oordt, K. Michelle Vanderwel, Mark C. Vanderwel, Karen J. Vanderwolf, Juliana Vélez, Diana Carolina Vergara-Florez, Brian C. Verrelli, Marcus Vinícius Vieira, Nora Villamil, Valerio Vitali, Julien Vollering, Jeffrey Walker, Xanthe J. Walker, Jonathan A. Walter, Pawel Waryszak, Ryan J. Weaver, Ronja E. M. Wedegärtner, Daniel L. Weller, Shannon Whelan, Rachel Louise White, David William Wolfson, Andrew Wood, Scott W. Yanco, Jian D. L. Yen, Casey Youngflesh, Giacomo Zilio, Cédric Zimmer, Gregory Mark Zimmerman, Rachel A. Zitomer

“…The existence of substantial variability among analysis outcomes raises important questions about how ecologists and evolutionary biologists should interpret published results, and how they should conduct analyses in the future.…”
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Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigationResearch... by Karl Michaëlsson, Rui Zheng, John A. Baron, Tove Fall, Alicja Wolk, Lars Lind, Jonas Höijer, Carl Brunius, Eva Warensjö Lemming, Olga E. Titova, Bodil Svennblad, Susanna C. Larsson, Shuai Yuan, Håkan Melhus, Liisa Byberg, Hannah L. Brooke

“…The genetically determined concentration of nine proteins influenced fat mass, and one influenced lean body mass. Interpretation: These data reveal biological links between cardiovascular diseases and fragility fractures. …”
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Geography and age drive racial and ethnic disparities in hospital mortality for paediatric community-acquired pneumonia in the United States: a retrospective population based cohor... by Cody-Aaron L. Gathers, Nadir Yehya, Anireddy Reddy, Paula M. Magee, Vanessa C. Denny, Michelle R. Mayeda, Amanda O’Halloran, Sanjiv D. Mehta, Stephanie Wanamaker, Jessica C. Fowler, Garrett Keim

“…Among patients <1 year, Black patients in the South (OR 2.35, 95% CI 1.52–3.63, p < 0.001) and West (OR 2.47, 95% CI 1.35–4.49, p = 0.003) and Hispanic/Latino patients in the Northeast (OR 2.36, 95% CI 1.46–3.66, p = 0.031) had the highest mortality, relative to White patients <1 year in the Northeast. Interpretation: We found evidence of racial and ethnic disparities in mortality for children diagnosed with community-acquired pneumonia. …”
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Durvalumab and tremelimumab in patients with advanced rare cancer: a multi-centre, non-blinded, open-label phase II basket trialResearch in context by Abha A. Gupta, Anna Tinker, Derek Jonker, Rahma Jamal, Hal Hirte, Eric W. Winquist, Quincy Chu, Christian Kollmannsberger, Ralph Wong, Thierry Alcindor, Torsten O. Nielsen, Ming Tsao, Tricia R. Cottrell, Diane Provencher, John Hilton, Monika K. Krzyżanowska, Christine Elser, Sebastien Hotte, Joana Sederias, Siwei Zhang, Wei Tu, Janet Dancey

“…Grade 3/4 adverse events were rare, where 4 patients experienced grade 4 related events and39 patients experienced grade 3 events. Interpretation: Durvalumab + tremelimumab treatment resulted in meaningful responses in salivary carcinoma and CCCO and deserves further exploration in front-line studies. …”
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L’aqueduc de Fontanières : un cinquième aqueduc romain à Lyon ? by Jean-Yves Barbier

“…Gabut had already rightly observed at the end of the 19th century, that the water would indeed have flowed from south to north towards Lyon/Lugdunum, rendering obsolete prior interpretations of an extension of the Brévenne aqueduct from its arrival at Saint-Irénée towards the south-east. …”
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Changes of Narrative: Osvald Sirén’s Photographic Modeling of Modern Research on Chinese Garden by Jiuwen GU, Yuanfeng SHI, Shan JIA

“…His early research on art history profoundly influences his approach to expressing photography and his perspective on interpreting gardens. The gardens photographed by Osvald Sirén often depict spatial scenes of significant depth. …”
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