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5921
Clinical characteristics of EGFR-ctDNA shedders in EGFR-mutant NSCLC patients
Published 2025-02-01“…This study aims to understand the determinants for ctDNA shedding based on clinical characteristics of lung cancer patients, for a better interpretation of false negative results to be considered when ordering ctDNA analysis for clinical practice. …”
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5922
Deep-Learning-Based Land Cover Mapping in Franciacorta Wine Growing Area
Published 2025-01-01“…Additionally, addressing challenges such as data availability, computational resources, and model interpretability is essential for advancing the field of remote sensing, in support of biodiversity conservation and the provision of ecosystem services and sustainable agriculture.…”
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5923
INTERFAITH MARRIAGE CONTROVERSIES IN SEMARANG: AN ANALYSIS OF QUR'ANIC LEGAL EXEGESIS
Published 2024-12-01“…This dispute includes discussions of Qur’anic interpretation and Islamic law as they assert different viewpoints regarding the legitimacy of marriage of Muslims with Ahl al-Kitab. …”
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5924
Attitudes toward artificial intelligence and robots in healthcare in the general population: a qualitative study
Published 2025-01-01“…The interviews were transcribed and analyzed using the MAXQDA Analytics Pro 2022 program (release 22.7.0). An interpretative approach to qualitative content analysis was applied to the responses to the research questions.ResultsThe analysis of interviews yielded three main themes: positive and negative perceptions of the use of AI and robots in healthcare and ontological concerns about AI, which went beyond objections about the usefulness of the technology. …”
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5925
Epidemiology and Resistance Profiles of Bacteria Isolated From Blood Samples in Septic Patients at Emergency Department Admission: A 6-Year Single Centre Retrospective Analysis Fro...
Published 2025-03-01“…Drug resistance was interpreted using EUCAST-2023. Clinical features included age, sex, comorbidities (e.g., cancer, diabetes), infection source, presence of central venous catheters (CVC), ongoing therapies, and sepsis severity. …”
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5926
Multi-task aquatic toxicity prediction model based on multi-level features fusion
Published 2025-02-01“…Moreover, ATFPGT-multi utilizes attention scores to identify molecular fragments associated with fish toxicity in organic molecules, as demonstrated by two organic molecule examples in the main text, demonstrating the interpretability of ATFPGT-multi. Conclusion: In summary, ATFPGT-multi provides important support and reference for the further development of aquatic toxicity assessment. …”
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5927
Cortical lesions impact cognitive decline in multiple sclerosis via volume loss of nonlesional cortex
Published 2025-01-01“…Mediation analysis showed that the effect of cortical lesions on future cognition was mediated by volume loss of the normal‐appearing instead of lesional cortex, independent of white matter lesion volume. Interpretation Multiple sclerosis‐related cortical thinning was worse in lesional compared to normal‐appearing cortex, while volume loss of normal‐appearing cortex was most predictive of subsequent cognitive decline, particularly in the default mode network. …”
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5928
Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey
Published 2024-05-01“…Although our results support a predominant role of bottom-up mechanisms, whereby hyaena density is driven by herbivore density, itself driven by resources availability, some subtle patterns of densities could be interpreted as consequences of changes in predation pressure following changes in scavenging opportunities. …”
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5929
Visualization of Right Adrenal Vein in Non‐Contrast‐Enhanced MDCT and Its Guiding Role for Right Adrenal Venous Sampling
Published 2025-01-01“…Furthermore, RAV images obtained from non‐contrast‐enhanced MDCT are highly consistent with those from AVS, indicating that interpretation of non‐contrast‐enhanced MDCT before AVS can reduce the failure rate of RAV cannulation.…”
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5930
Accumulation conditions and target area evaluation of coalbed methane in eastern uplift of Junggar Basin
Published 2025-01-01“…Utilizing well logging data, core analysis test results, and seismic data, well-seismic calibration and seismic profile interpretation were carried out. Connecting-well profiles and thickness distribution maps for coal seams in the Jurassic Xishanyao and Badaowan formations were compiled. …”
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5931
Energetic and genomic potential for hydrogenotrophic, formatotrophic, and acetoclastic methanogenesis in surface-expressed serpentinized fluids of the Samail Ophiolite
Published 2025-01-01“…These results demonstrate the applicability of an energy availability framework for interpreting methanogen ecology in serpentinizing systems.…”
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5932
Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort studyResearch in context
Published 2025-01-01“…In regression models, differences at 5 and 12 months were attenuated after adjustment for BMI and presence of other long-term conditions. Interpretation: People with diabetes reported worse physical outcomes up to 12 months after hospital discharge with COVID-19 compared to those without diabetes. …”
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5933
Socioeconomic characteristics and relapse-free and overall survival from childhood cancer – a nationwide study based on data from the Danish Childhood Cancer Registry
Published 2025-01-01“…Cox proportional hazards models were used to estimate the association between SEP indicators and 5-year RFS and OS. Results and interpretation: Tendencies towards lower 5-year RFS and OS were observed among children whose parents were unemployed/not in workforce (RFS: HR [hazard ratio] = 1.14, 95% CI [confidence interval]: 0.90–1.45, OS: HR = 1.28, 95% CI: 0.95–1.71) or from non-Western countries (RFS: HR = 1.21 95% CI: 0.96–1.52, OS: HR = 1.44, 95% CI: 1.09–1.90). …”
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5934
Development and validation of a prognostic prediction model for elderly gastric cancer patients based on oxidative stress biochemical markers
Published 2025-02-01“…The SHapley Additive exPlanations (SHAP) method was used for model interpretation. Results This study included a total of 1,859 older patients. …”
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5935
Synthesis of Nanocrystalline Mn-Doped Bi<sub>2</sub>Te<sub>3</sub> Thin Films via Magnetron Sputtering
Published 2025-01-01“…Structural analysis indicated the presence of a secondary <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>MnTe</mi><mi>x</mi></msub></mrow></semantics></math></inline-formula> phase, which complicates the interpretation of the magnetic properties. Additionally, the incorporation of Mn ions within the van der Waals gap and substitutional doping on Bi sites contributes to the observed complex magnetic properties. …”
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5936
Peripheral blood age-sensitive immune markers in multiple sclerosis: relation to sex, cytomegalovirus status, and treatmentResearch in context
Published 2025-02-01“…Finally, lower levels of IL-6, TNF, IL-10, and β-NGF were observed at baseline in PwMS who subsequently experienced clinical failure after DMTs initiation. Interpretation: Age, sex, CMV status, and specific DMTs significantly influence levels of age-sensitive immune biomarkers associated with MS and must be considered when investigating inflammation-related biomarkers. …”
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5937
Investigation of a Novel Noninvasive Risk Analytics Algorithm With Laboratory Central Venous Oxygen Saturation Measurements in Critically Ill Pediatric Patients
Published 2025-01-01“…The central venous oxygen saturation (Svo2) enables an estimate of cardiac output yet obtaining these clinical data requires invasive procedures and repeated blood sampling. Interpretation remains subjective and vulnerable to error. …”
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5938
Multiple patterns of EEG parameters and their role in the prediction of patients with prolonged disorders of consciousness
Published 2025-02-01“…A combination of machine learning and SHapley Additive exPlanations (SHAP) were used to develop predictive model and interpret the results.ResultsThe results indicated significant abnormalities in low-frequency spectral power, microstate parameters, and amplitudes of MMN and P3a in MCS and UWS. …”
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5939
Circulating tumor DNA for surveillance in high-risk melanoma patients: a study protocol
Published 2025-02-01“…This allows determination of the value and sensitivity of ctDNA for early detection of recurrence. Results and Interpretation: For validation purposes, we conducted a small pilot study using blood samples from 10 patients who had experienced recurrence and had a clinically confirmed BRAF V600E mutation. …”
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5940
Germline BRCA testing in Denmark following invasive breast cancer: Progress since 2000
Published 2025-01-01“…BRCA test rates were higher for oestrogen receptor-negative/human epidermal growth factor receptor 2-negative BC (25% in 2000–2005 vs. 38% in 2012–2017), and these findings were confirmed in multivariate regression models. Interpretation: Our results indicate a critical need for an intensified focus on BRCA testing among BC patients older than 40, where a mainstreamed testing approach might overcome delayed or missed testing. …”
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