Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein by Marie-Lynn Cuypers, Tom Jaspers, Jarne Clerckx, Simon Leekens, Christopher Cawthorne, Guy Bormans, Frederik Cleeren, Nick Geukens, Bart De Strooper, Maarten Dewilde

“…Additional MOG binding of antibodies does not affect peripheral biodistribution but alters brain distribution to white matter localization and less neuronal internalization. Conclusions We have discovered mouse/human/cynomolgus cross-reactive anti-MOG VHHs which have the ability to drastically increase brain exposure of antibodies. …”
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Association of leukocyte telomere length with the risk of digestive diseases: A large-scale cohort study by Hongqun Yang, Lanlan Chen, Yahui Liu, Jinjiao Li

“…After a mean follow-up time of 11.8 years, over 20 International Classification of Diseases, 10th Revision (ICD-10) codes were showed to be associated with telomere attrition. …”
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Assessing the potential of germplasm collections for the management of genetic diversity: the case of the French National Cryobank by Jacques, Alicia, Duclos, Delphine, Danchin-Burge, Coralie, Mercat, Marie-José, Tixier-Boichard, Michèle, Restoux, Gwendal

“…These indicators can be calculated at regular intervals to support the planning and management of collections at national and international levels and help population managers to exploit the resources currently available. …”
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Strengthening research preparedness for crises: lessons from Norwegian government agencies in using randomized trials and quasi-experimental methods to evaluate public policy inter... by Unni Gopinathan, Ingeborg Elgersma, Therese Dalsbø, Mona Bjørbæk, Atle Fretheim

“…The measures evaluated included organizational, educational and financial interventions and interventions for oversight and sanctions. Some agencies have internal capabilities for designing and conducting evaluations, while others commissioned such studies to universities and other research institutions. …”
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Tibiofemoral Joint Contact Force Estimation Based on OpenSim Musculoskeletal Modeling by WANG Xiaoling, JIAN Jiawei, XIE Qiurong, LIAN Zhanghui, GUO Chunming, GUO Jiemei, LI Yurong

“…Through the model scale, inverse kinematics, inverse dynamics analysis, residual reduction processing and muscle control and analysis, medial/lateral tibiofemoral contact force is estimated during walking gait, considering the contribution of external force and internal muscle strength. MATLAB 2018b is used for statistical analysis. …”
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Tropical upper-tropospheric trends in ozone and carbon monoxide (2005–2020): observational and model results by L. Froidevaux, D. E. Kinnison, B. Gaubert, M. J. Schwartz, N. J. Livesey, W. G. Read, C. G. Bardeen, J. R. Ziemke, J. R. Ziemke, R. A. Fuller

“…</p> <p>Our tropical composition trend results contribute to continuing international assessments of tropospheric evolution.</p>…”
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Efficacy and prognosis of dapagliflozin in the treatment of patients with acute myocardial infarction complicated with type 2 diabetes in Xining area by Jinping Chai, Delian Li, Yanmin Liu, Xiaoling Su

“…The objective of this study is to investigate the efficacy and prognosis of dapagliflozin in patients with acute myocardial infarction complicated by type 2 diabetes in the Xining region.Methodanalysis on January 1, 2018 to January 1, 2020, in Qinghai province people's hospital of cardiovascular internal medicine hospital treatment of 245 cases of acute myocardial infarction combined the clinical data of patients with type 2 diabetes. …”
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Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing by Roldan Munoz S, Mol PGM, de Vries F, van Dijk PR, Hillege H, Postmus D, de Vries ST

“…Sonia Roldan Munoz,1 Peter GM Mol,1 Femke de Vries,2 Peter R van Dijk,3 Hans Hillege,4 Douwe Postmus,4 Sieta T de Vries1 1Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 2Faculty of Beta Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; 3Division of Endocrinology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 4Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsCorrespondence: Sieta T de Vries, Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, Email s.t.de.vries@umcg.nlBackground: Treatment guidelines recommend metformin as initial drug in many people with type 2 diabetes (T2D) and low risk of cardiovascular disease, with the possibility to switch to or add other drug classes. …”
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SOME ASPECTS OF THE ANALYSIS OF CYCLICAL FLUCTUATIONS IN THE ECONOMY (IN THE CASE OF THE CORONAVIRUS PANDEMIC CRISIS) by Kamoliddin Jabbarov

“…Key suggestions include expanding digiti­zation, maintaining strict public health measures, gradually resuming economic activities with ap­propriate safety protocols, and fostering international cooperation to ensure a coordinated response to the crisis. …”
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Data-Sharing Statements Requested from Clinical Trials by Public, Environmental, and Occupational Health Journals: Cross-Sectional Study by Yingxin Liu, Jingyi Zhang, Lehana Thabane, Xuerui Bai, Lili Kang, Gregory Y H Lip, Harriette G C Van Spall, Min Xia, Guowei Li

“…Sharing individual participant data in public, environmental, and occupational health trials can help improve public trust and support by enhancing transparent reporting and reproducibility of research findings. The International Committee of Medical Journal Editors (ICMJE) requires all papers to include a data-sharing statement. …”
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Guideline: Neurorehabilitation in patients with disorder of consciousness. Recommendations from the Spanish Society of Neurorehabilitation by E. Noé, M.D. Navarro, B. Moliner, M. O’Valle, J. Olaya, A. Maza, R. Llorens, J. Ferri, R. Rodríguez, T. Pérez, M. Bernabéu, C. Colomer, A. Gómez, C. González, A. Juárez-Belaúnde, C. López, S. Laxe, R. Pelayo, M. Ríos, I. Quemada, Enrique Noé Sebastián, María Dolores Navarro Pérez, Belén Moliner Muñoz, Myrtha O’Valle Rodríguez, José Olaya Sanchez, Roberto Llorens Rodríguez, Anny Maza Pino, Joan Ferri Campos, Rubén Rodríguez Duarte, Teresa Pérez Nieves, Montserrat Bernabeu, Carolina Colomer Font, Antonio Gómez Blanco, Carlos González Alted, Alan Juárez Belaúnde, Cristina López Pascua, Sara Laxe García, Raúl Pelayo Vergara, Marcos Ríos Lago, Ignacio Quemada

“…This document is based on a review of international clinical practice guidelines published between 2015 and 2022. …”
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Regulatory problems and developmental psychopathology within the first 2 years of living—a nested in cohort population-based study by Janni Ammitzbøll, Janni Ammitzbøll, Anne Lise Olsen, Susanne Landorph, Christian Ritz, Anne Mette Skovgaard, Anne Mette Skovgaard

“…Follow-up at 1½ years included diagnostic assessment according to the International Classification of Diseases, ICD-10, and the Diagnostic Classification of Mental Health and Developmental Disorders in Infancy and Early Childhood: Revised edition, DC:0-3R. …”
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Efficacy and Acceptability of a Mobile App for Monitoring the Clinical Status of Patients With Chronic Obstructive Pulmonary Disease Receiving Home Oxygen Therapy: Randomized Contr... by Anisbed Naranjo-Rojas, Luis Ángel Perula-de Torres, Freiser Eccehomo Cruz-Mosquera, Guillermo Molina-Recio

“…Trial RegistrationClinicalTrials NCT04820790; https://clinicaltrials.gov/study/NCT04820790 International Registered Report Identifier (IRRID)RR2-https://doi.org/10.1186/s12875-021-01450-8…”
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Structure of mycoses of the skin and its appendices in HIV-infected patients by V.D. Moskaliuk, I.I. Kravchuk, Yu.O. Randiuk, I.V. Balaniuk

“…The diagnosis of HIV infection was established according to the International Classification of Diseases of the 10th revision (ICD-10) and verified by the detection of specific serological and molecular biological markers of HIV. …”
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Access to Health Care and Use of Health Care Services Among Males in Africa: Protocol for a Scoping Review by Nkoleleng Johannah Mashilo, Kelechi Elizabeth Oladimeji, Siphamandla Gumede, Samanta Tresha Lalla-Edward

“…Trial RegistrationOSF Registries https://osf.io/xz6sr International Registered Report Identifier (IRRID)DERR1-10.2196/52351…”
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Book phenomenon in library philosophy and library research by Baiba Sporane

“…A person can comprehend, experience, and understand a book's internal being, valuing the book as a phenomenon, not just as a piece of material culture. …”
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Molecular mapping and validation of quantitative trait loci for content of micronutrients in wheat grain by Xiangdong Chen, Junchao You, Nannan Dong, Di Wu, Die Zhao, Rui Yong, Wenjing Hu

“…A total of 60 and 51 high-confidence annotated genes for QFe/Se.yaas-2D and QMn/Zn.yaas-4D were identified using the International Wheat Genome Sequencing Consortium Reference Sequence v2.1 (IWGSC RefSeq v2.1), respectively. …”
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Medicaid Eligibility and Time to Re-incarceration Among Previously Incarcerated Subjects With Schizophrenia by Chris Kozma, Michael Dickson, Jacqueline Pesa, Carmela J. Benson

“…Subjects were included if they had a schizophrenia diagnosis (International Classification of Diseases, 9th Revision, Clinical Modification [ICD- 9-CM] code 295.xx), were between the ages of 18 and 62, and had been released from incarceration. …”
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Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials by Hillary Norton, Paula Sliwinska-Stanczyk, Tomas Hala, Bassel El-Zorkany, Lori Stockert, Rajiv Mundayat, Lisy Wang, Christopher T. Ritchlin

“…Across categories, tofacitinib responses/improvements were greater than with placebo, except for ≥ 40% Assessment of SpondyloArthritis international Society improvement (ASAS40), ASAS partial remission, 50% improvement from baseline in the Bath Ankylosing Spondylitis Disease Activity Index score (BASDAI50), and Ankylosing Spondylitis Disease Activity Score using C-reactive protein (ASDAS-CRP) inactive disease rates, which were similar for tofacitinib and placebo in the BMI ≥ 30 kg/m2 category. …”
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Research trends in farmers' mental health: A scoping review of mental health outcomes and interventions among farming populations worldwide. by Briana N M Hagen, Ashley Albright, Jan Sargeant, Charlotte B Winder, Sherilee L Harper, Terri L O'Sullivan, Andria Jones-Bitton

“…The objectives of this scoping review were to: provide a descriptive analysis of the literature pertaining to mental health outcomes in farming populations; describe the international scope of the research; and highlight published mental health services and interventions that have been evaluated.…”
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