Comparison of different GnRH compounds on fertility outcomes in ovulation synchronized and presynchronized beef cows by Nicola Oosthuizen, Lucas M. Goncalves, Samir Burato, Molly S. Smith, Kelsey M. Harvey, Graham Cliff Lamb, Graham Cliff Lamb, Pedro L. P. Fontes

“…Within each location, cows were randomly assigned to one of four treatments: (1 and 2) cows were estrus synchronized using the 7-day CO-Synch + CIDR protocol (7D) wherein they received an injection of one of two GnRH compounds [gonadorelin hydrochloride (GH) or gonadorelin diacetate tetrahydrate (GDT)] and a controlled internal drug release (CIDR) device on day 0, an injection of prostaglandin F2α (PG) at CIDR removal on day 7, and a second injection of their respective GnRH compound at fixed-time artificial insemination (TAI) on day 10 (7D-GH and 7D-GHT); (3 and 4) cows were treated with the 7&7 Synch (7&7) protocol, wherein they were treated the same as treatments 1 and 2 but received their CIDR inserts on day -7 in conjunction with an injection of PG (7&7-GH and 7&7-GDT). …”
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Literature study of Zn supplementation in feed for optimizing Nile tilapia Oreochromis niloticus growth by Muhammad Agus Suprayudi, Hendri Inarto, Julie Ekasari

“…The literature sources were obtained from accredited national journals, international journals, research outcomes, theses, and dissertations over the past 20 years. …”
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Large-scale spatio-temporal variation in vital rates and population dynamics of an alpine bird by Nater, Chloé R., Frassinelli, Francesco, Martin, James A., Nilsen, Erlend B.

“…Our study highlights the potential of participatory monitoring and 2integrated modelling approaches for estimating and understanding spatio-temporal patterns in species abundance and demographic rates, and showcases how corresponding workflows can be set up in reproducible and semi-automated ways that increase their usefulness for informing management and regular reporting towards national and international biodiversity frameworks.…”
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Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-labe... by Ying Zhu, Jianwei Zhou, Zhigang Zhang, Jiaojiao Zhang, Jing Fei, Xiaoqing Zhu

“…The NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr(NAIVE) study aims to assess the clinical efficacy and safety of NACT in combination with tislelizumab (a monoclonal antibody for programmed cell death protein 1) for advanced EOC.Methods and analysis The NAIVE study is an investigator-initiated, prospective, single-centre, open-label, randomised controlled trial for advanced EOC with the International Federation of Gynaecology and Obstetrics (FIGO) stage IIIc with a Suidan CT score of 3 or greater or a Fagotti laparoscopic score of 8 or greater; or FIGO stage IV. …”
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Mycobiome analyses of critically ill COVID-19 patients by Danielle Weaver, Sara Gago, Matteo Bassetti, Daniele Roberto Giacobbe, Juergen Prattes, Martin Hoenigl, Florian Reizine, Hélène Guegan, Jean-Pierre Gangneux, Michael John Bromley, Paul Bowyer

“…Respiratory mycobiome was profiled using internal transcribed spacer 1 sequencing, and Aspergillus fumigatus burden was further validated using quantitative PCR. …”
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The carbon footprint of pasture-based buffalo milk production in Colombia by Andrés F. Pérez, Felipe Vélez S., Juan F. Naranjo R.

“…This study is adapted to the standards for life cycle assessment, focusing specifically on greenhouse gas emissions from the International Organization for  Standardization. Two functional units were used for measurement: tons of CO 2 -equivalents (CO 2e ) per hectare (ha) and kilograms of CO 2e per kilogram of fat-and-protein-corrected milk (FPCM). …”
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Using microfluidic shear to assess transfusion requirements in trauma patients by Rachael A Callcut, James T Ross, Anamaria J Robles, Leslie H Vuoncino, Ashli C Barnes, Leonardo W Graeff, Taylor L Anway, Nico T Vincent, Nithya Tippireddy, Kimi M Tanaka, Randi J Mays

“…Median age was 37.5 (IQR 27.5–52) years; patients were 77% male. 71% suffered blunt trauma, 26% had an Injury Severity Score of ≥25. An elevated international normalized ratio significantly correlated with decreased cumulative PCF (p=0.05), maximum PCF (p=0.05) and CA (p=0.02). …”
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Temples of Katas: Their Historical and Religious Significiance by Muhammad Usman Ali

“…The foremost issue associated with Raj Katas is that no author of international standing has worked on this topic. …”
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Serial measurements in COVID-19-induced acute respiratory disease to unravel heterogeneity of the disease course: design of the Maastricht Intensive Care COVID cohort (MaastrICCht) by Steven J R Meex, Walther N K A van Mook, Iwan C C van der Horst, Jeanette Tas, Coen D A Stehouwer, Rob J J van Gassel, Serge J H Heines, Mark M G Mulder, Nanon F L Heijnen, Melanie J Acampo-de Jong, Julia L M Bels, Frank C Bennis, Marcel Koelmann, Rald V M Groven, Moniek A Donkers, Frank van Rosmalen, Ben J M Hermans, Otto Bekers, Astrid M L Oude Lashof, Fabian H Tijssen, Jan-Willem E M Sels, Chahinda Ghossein-Doha, Rob G H Driessen, Pieter L Kubben, Marcus L F Janssen, Gerry A F Nicolaes, Ulrich Strauch, Zafer Geyik, Thijs S R Delnoij, Kim H M Walraven, Jeanine A M C F Verbunt, Susanne van Santen, Ronny M Schnabel, Marcel J H Aries, Marcel C G van de Poll, Bas C T van Bussel, Joachim E Wildberger, Sander M J van Kuijk, Dennis C J J Bergmans, Paul H M Savelkoul, Alma M A Mingels, Wolfgang F F A Buhre

“…Therefore, a major part of the data collection is aligned with an existing national intensive care data registry and two international COVID-19 data collection initiatives. Additionally, we create a flexible design, so that additional measures can be added during the ongoing study based on new knowledge obtained from the rapidly growing body of evidence. …”
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TIKROVĖS POSTMODERNIOS GRIMASOS by Audronė Žukauskaitė

“…After the critical debates with Judith Butler and Charles Chepherdson on the ambivalent character of the Real, Žižek refined his position and defined the Real as the internal limit of the symbolical order. The article discusses the ambivalent character of the Real and its implications on sexual, ethical and political fields. …”
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Burden of early neonatal mortality in Sub-Saharan Africa. A systematic review and meta-analysis. by Natnael Moges, Anteneh Mengist Dessie, Denekew Tenaw Anley, Melkamu Aderajew Zemene, Natnael Atnafu Gebeyehu, Getachew Asmare Adella, Gizachew Ambaw Kassie, Misganaw Asmamaw Mengstie, Mohammed Abdu Seid, Endeshaw Chekol Abebe, Molalegn Mesele Gesese, Yenealem Solomon Kebede, Sefineh Fenta Feleke, Tadesse Asmamaw Dejenie, Natnael Amare Tesfa, Wubet Alebachew Bayih, Ermias Sisay Chanie, Berihun Bantie

“…Therefore, governmental and nongovernmental agencies, international organizations, healthcare providers and institutions and academic and research institutions should give a due attention and design strategies to reduce early neonatal mortality in Sub-Saharan Africa.…”
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Altered Topological Properties of Grey Matter Structural Covariance Networks in Complete Thoracic Spinal Cord Injury Patients: A Graph Theoretical Network Analysis by Wen-Li Wang, Yu-Lin Li, Mou-Xiong Zheng, Xu-Yun Hua, Jia-Jia Wu, Fei-Fei Yang, Nan Yang, Xia He, Li-Juan Ao, Jian-Guang Xu

“…Partial correlation analysis was performed to explore the relationship between the GMV of structurally changed brain regions and SCI patients’ clinical variables, including injury duration, injury level, Visual Analog Scale (VAS), American Spinal Injury Association Impairment Scale (AIS), International Classification of Functioning, Disability and Health (ICF) scale, Self-rating Depression Scale (SDS), and Self-rating Anxiety Scale (SAS), after removing the effects of age and gender. …”
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Safety and Efficacy of Combination Therapy with Anti-Vascular Endothelial Growth Factor and Laser for Retinopathy of Prematurity: A Systematic Review and Meta-Analysis by Alamoudi A, Alnabihi AN, Alsudais AS, Almufarriji N, Batais WT, Aldahlawi AK, Altalhi A, Al-Dhibi HA, Alakeely AG

“…Anas Alamoudi,1 Ahmed N Alnabihi,2,3 Ali Saleh Alsudais,2,3 Naif Almufarriji,1 Waleed T Batais,2,3 Abdulaziz Khalid Aldahlawi,2,3 Abdullah Altalhi,4 Hassan A Al-Dhibi,5 Adel G Alakeely6 1Department of Ophthalmology, Jeddah Eye Hospital, Jeddah, Saudi Arabia; 2College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia; 3King Abdullah International Medical Research Center, Jeddah, Saudi Arabia; 4Division of Vitreoretinal Surgery, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 5Division of Vitreoretinal Surgery and Uveitis, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 6Magrabi Hospitals and Centers, Riyadh, Saudi ArabiaCorrespondence: Anas Alamoudi, Department of Ophthalmology, Jeddah Eye Hospital, Jeddah, Saudi Arabia, Email anasalamoudi99@gmail.comAim: This systematic review and meta-analysis aimed to evaluate the safety and efficacy of combined laser and anti-VEGF therapy for (retinopathy of prematurity ROP), focusing on both structural and functional outcomes.Methods: A comprehensive search was conducted in multiple databases to identify randomized controlled trials (RCTs) that investigated combination therapy for ROP. …”
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Outcomes of different surgical procedures for optic disc pit: a meta-analysis by Hussain A. Khaqan, Raheela Naz, Hafiz A. ur Rehman, Laraib Hassan, Nabeel Akram, Hafiz M. Farooqui, Ahmad Fauzan, Asad M. Khan

“…We identified the following commonly reported techniques: juxtapapillary laser alone, PPV alone or with juxtapapillary laser (PPV/JPL), internal limiting membrane peeling (PPV/ILMP), both ILMP and JPL (PPV/ILMP/JPL), inner retinal fenestration (PPV/IRF), autologous platelet concentrate (PPV/APC), macular buckling alone or with PPV, PPV with ocriplasmin (PPV/OCR) and PPV with autologous scleral flap. …”
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Healthcare performance of leprosy management in peripheral health facilities of Dhanusa and Mahottari, Nepal by Ram Kumar Mahato, Uttam Ghimire, Bijay Bajracharya, Binod K. C., Deepak Bam, Deepak Ghimire, Uttam Raj Pyakurel, David T. S. Hayman, Basu Dev Pandey, Chuman Lal Das, Krishna Prasad Paudel

“…., 0, 1) and then rescaled to a proportion, where 1 is perfect. Internal benchmarking was used to guide performance management. …”
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Feasibility of a Mobile App–Based Cognitive-Behavioral Perinatal Skills Program: Protocol for Nonrandomized Pilot Trial by Andrea B Temkin-Yu, Aliza Ayaz, Ella Blicker, Michael X Liu, Ace Oh, Isabelle E Siegel, Meredith J Seewald, Alison D Hermann, Soudebah Givrad, Lara M Baez, Lauren M Osborne, Cori M Green, Maddy M Schier, Alexandra M Davis, Shasha Zhu, Avital Falk, Shannon M Bennett

“…Trial RegistrationClinicalTrials.gov NCT05897619; https://classic.clinicaltrials.gov/ct2/show/NCT05897619 International Registered Report Identifier (IRRID)PRR1-10.2196/59461…”
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La villégiature anglaise et l’invention de la Côte d’Azur by Alain Bottaro

“…Finally came « launch time », as the expression goes: that is, the progressive inclusion of local towns in the ranks of top resorts for international travelers. It is indeed above all a British invention: from the second half of the 18th century to the 20th century, travelers from the British Isles were the creators, the propagators, and the main protagonists of the Riviera as a touristic haven. …”
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UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research by Zhan R, Liu Y, Wu J, Shen Y, Xu X, Lin G, Chen X

“…Ruanjuan Zhan,1,* Yanan Liu,1,2,* Jun Wu,1,2 Yuxin Shen,1,2 Xinhao Xu,1,2 Guanyang Lin,1,2 Xiaocheng Chen1 1The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanyang Lin; Xiaocheng Chen, Email 13867702133@163.com; cxcwzcn@139.comBackground: Givinostat, a potent histone deacetylase (HDAC) inhibitor, is promising for the treatment of relapsed leukemia and myeloma.Purpose: This study aimed to develop and verify a quick assay for the measurement of givinostat concentration using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) with eliglustat as the internal standard (IS), establishing a basic pharmacokinetic profile for its pre-clinical application and metabolic stability in vitro.Methods: Sample preparation was performed via protein precipitation using acetonitrile. …”
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Use of extracorporeal shockwave therapy combined with standard rehabilitation following anterior cruciate ligament reconstruction: a systematic review with meta-analysis by Jaehyung Shin, Hye Chang Rhim, James Kim, Raymond Guo, Ramy Elshafey, Ki-Mo Jang

“…The meta-analysis demonstrated that the Lysholm scores were significantly higher in ESWT groups than those of controls at 12 months (Weighted mean difference [WMD]: 7.037, 95% confidence interval [CI]: 6.172–7.902, I2: 0%) and 24 months (WMD: 5.463, 95% CI: 2.870–8.056, I2: 0%). Furthermore, the International Knee Documentation Committee (IKDC) scores were also significantly higher in the ESWT group than that of the control at 12 months (WMD: 6.371, 95% CI: 3.397–9.344, I2: 68.8%). …”
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Associations between disease severity, depression, health-related quality of life, and physical activity in adults with sickle cell disease by Adekola B. Ademoyegun, Mutiu A. Adeyemo, Babatunde Y. Adewuyi, Adebukola G. Ibitoye, Olalekan I. Akerele, Taofeek O. Awotidebe, Chidozie E. Mbada

“…Data on DS, depression, HRQoL, and PA were assessed through modified disease severity scoring protocol, patient health questionnaire-9, 12-item short-form health survey, and international physical activity questionnaire short-form, respectively. …”
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