Feasibility assessment of a pharmaco-kinetic behavior based yield model of salivary cotinine among tobacco users by E.C. Hensel, R.J. Robinson

“…Conclusions: The PkBBY model was internally validated and shows promise as a tool for establishing a causal relationship between puffing behavior and an established biomarker of nicotine exposure. …”
Get full text

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach by Pei Liu, Lin Xu, Jing-han Guo, Jin-hua Chang, Xi-gang Liu, He-fei Xue, Ru-xing Wang, Zhong-si Li, Guang-xin Miao, Cui-zhe Liu, Jian-yu Zhou

“…The aim of the present study was to establish an efficient, sensitive ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach for pharmacokinetic analysis of diosgenin amorphous solid dispersion (ASD) using tanshinone IIA as an internal standard (IS). Male Sprague-Dawley rats were orally administered diosgenin ASD, and orbital blood samples were collected for analysis. …”
Get full text

Bipolar affective disorder in India: A multi-site population-based cross-sectional study by Bhavika Vajawat, Satish Suhas, Sydney Moirangthem, Channaveerachari Naveen Kumar, Mathew Varghese, Gopalkrishna Gururaj, Vivek Benegal, Girish N. Rao, NMHS National Collaborators Group

“…The diagnosis of BPAD was based on Mini-International Neuropsychiatric Interview 6.0.0. Sheehan's Disability Scale was used to assess the disability. …”
Get full text

On being and having: a qualitative study of self-perceptions in bipolar disorder by Matthew N. Ponticiello, Alexis L. Chang, Rebecca J. Chang, Salahudeen Mirza, Andrés Martin

“…We coded the transcripts according to the principles of thematic analysis and analyzed the data using an interpretative phenomenological analysis approach.ResultsWe identified three overarching domains: (1) Benefit or burden: a dialectic through which participants weighed the valence of their illness over time; (2) Self or other: the internal or external locus through which they experienced BD; and (3) From ineffability to meaning making: the process of naming, understanding, and incorporating BD into their life’s whole. …”
Get full text

Effectiveness of supracondylar dome osteotomy in reducing lateral condylar prominence and enhancing functional outcomes in pediatric cubitus varus: a retrospective study by Yam Prakash Gurung, Sabin Pokharel, Rajan Bhusal, Tarun Rajbhandari, Ashok Kumar Banskota, Bibek Banskota

“…Abstract Background Cubitus varus, a common complication of pediatric supracondylar humerus fractures, presents with internal rotation, extension, and varus angulation. …”
Get full text

Achieving equiaxed and lamellar TiAl alloys via cold-cathode electron beam additive manufacturing with dual-wire synergistic control by Yilei Shi, Shuili Gong, Haiying Xu, Wei Chen, Zhuang Wang, Guang Yang, Xin Liu, Bojin Qi

“…Mo, Zr, and Si elements were introduced into the TiAl alloy, and precise thermal control allowed the separated twin wires to simultaneously form a stable co-molten pool, and the specimens with good appearance and no internal microcracks and pores were obtained. Furthermore, a detailed comparison between Ti48Al alloy and Ti48Al1Mo0.45Zr0.3Si alloy was carried out, focusing on aspects such as grain morphology, chemical composition homogeneity, phase constitution, and mechanical properties. …”
Get full text

Epidemiology and clinical features of childhood malignant solid tumors in a single center in southwest China over 24 years by Ting Li, Xiangpan Kong, Dawei He

“…They were classified according to the International Classification of Childhood Cancer, Third Edition (ICCC-3). …”
Get full text

Binge eating disorder recognition and stigma among an adult community sample by Marilou Côté, Marie-Pier Roy, Christopher Rodrigue, Catherine Bégin

“…., gender, age, income, education) and psychosocial variables (i.e., explicit and internalized weight bias, familiarity with BED). A multiple linear regression analysis was performed to identify the sociodemographic and psychosocial variables that were the most important in explaining the variance in stigma towards BED. …”
Get full text

The Tools for Integrated Management of Childhood Illness (TIMCI) study protocol: a multi-country mixed-method evaluation of pulse oximetry and clinical decision support algorithms by Fenella Beynon, Hélène Langet, Leah F. Bohle, Shally Awasthi, Ousmane Ndiaye, James Machoki M’Imunya, Honorati Masanja, Susan Horton, Maymouna Ba, Silvia Cicconi, Mira Emmanuel-Fabula, Papa Moctar Faye, Tracy R. Glass, Kristina Keitel, Divas Kumar, Gaurav Kumar, Gillian A. Levine, Lena Matata, Grace Mhalu, Andolo Miheso, Deusdedit Mjungu, Francis Njiri, Elisabeth Reus, Michael Ruffo, Fabian Schär, Kovid Sharma, Helen L. Storey, Irene Masanja, Kaspar Wyss, Valérie D’Acremont, TIMCI Collaborator Group

“…Findings will be shared with communities, healthcare providers, Ministries of Health and other local, national and international stakeholders to facilitate evidence-based decision-making on scale-up. …”
Get full text

Cyclical Inclusive Growth Model of the European Union by E. V. Sapir, A. D. Vasilchenko

“…As an integration entity, the EU contends with a series of internal challenges that impede its development, arising from the divergent economic interests of member states and the uneven distribution of the costs and benefits of the 'twin transition' in the context of Europe’s declining global competitiveness. …”
Get full text

Examination of the physical profiles of physically handicapped female badminton players by Mehmet Fatih Yüksel

“…In accordance with the obstacle classification determined by the International Physically Handicappeds Badminton Federation, handicapped female badminton players were composed of two groups including SL-3, SL-4, SU-5 (standing players, n= 11) and WH-1, WH-2 (wheelchair players, n= 9). …”
Get full text

Mechanical Mechanism of Water Injection to Enhance the Stability of Soft Coal by Chuanqi Zhu, Hao Fan, Wanrong Liu, Shaobo Li

“…The cohesive force increases first and then decreases, while the angle of internal friction almost has no change. (4) After reasonable water injection, the shape of liquid bridge in coal body changes into capillary tube, and the liquid bridge force reaches the maximum value, which transforms from a highly unstable bulk to a stable continuum. …”
Get full text

Risk factors for disruptive behaviours: protocol for a systematic review and meta-analysis of quasi-experimental evidence by Essi Viding, Francesca Solmi, Simon Russell, Lucy Karwatowska, Bianca Lucia De Stavola, Sara Jaffee, Jean-Baptiste Pingault

“…The findings will be disseminated via publication in a peer-reviewed scientific journal and through presentations at international meetings and conferences.PROSPERO registration number CRD42020169313.…”
Get full text

Social Participation of the Russian and Armenian Students in the Socio-Cultural Development of Cities by M. V. Pevnaya, E. A. Shuklina, A. N. Tarasova, L. A. Asoyan

“…The article was prepared on the basis of an international comparative study – a sociological survey of students from regional universities from 37 cities in the Sverdlovsk region of the Russian Federation and 20 settlements of the Shirak region in the Republic of Armenia (targeted sample, No. = 715). …”
Get full text

Preparation, Reliability, and Validity of a Japanese Version of the “Satisfaction of Treatment among Caregivers of Dependent Type 2 Diabetic Patients” Questionnaire by Satoshi Ida, Ryutaro Kaneko, Kanako Imataka, Kaoru Okubo, Yoshitaka Shirakura, Kentaro Azuma, Ryoko Fujiwara, Hiroka Takahashi, Kazuya Murata

“…Cronbach’s α coefficient was calculated to assess internal consistency. Exploratory factor analyses were performed to assess construct validity, and Pearson’s correlation coefficients between STCD2-J score and HbA1c as well as the degree of satisfaction with patients’ blood glucose levels, depression, and negative self-assessment of nursing care were calculated to assess criterion-related validity. …”
Get full text

Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal by Raffaele Falsaperla, Vincenzo Sortino, Gerhard Josef Kluger, Thomas Herberhold, Andrea Rüegger, Pasquale Striano, Martino Ruggieri, Joerg Klepper, Georgia Ramantani

“…Large‐scale multicenter studies, facilitated through international collaborations like the European Network for Therapy in Rare Epilepsies (NETRE), hold promise in elucidating the complexities of this patient population and developing personalized therapeutic approaches. …”
Get full text

Evolution of EFTA in Differentiated Integration within Europe by V. V. Zolotukhin

“…The thematic allocation is carefully structured based on existing competencies; officials of EFTA's pillar bodies within the two-pillar EEA structure maintain productive relations with the EU, while others focus on internal matters. The geographical location of these bodies plays a decisive role: Brussels and Luxembourg are aligned with a broad Eurocentric decision-making paradigm, while those within EFTA prioritize endogenous agendas.Switzerland's integration trajectory relies on a diverse array of regulatory mechanisms aimed at bridging disparate areas and fostering cooperation among participating states. …”
Get full text

HCFC-141b (CH3CCl2F) Emission Estimates for 2000–2050 in Eastern China by Dayu Zhang, Jing Wu, Zehua Liu, Tong Wang, Yueling Zhang, Dongmei Hu, Lin Peng

“…Abstract HCFC-141b (CH3CCl2F) has dual environmental impacts on ozone depletion and climate change, with the ozone depletion potential of 0.11 and the global warming potential of 782, and its emissions has attracted international attention. Under the control of the Montreal Protocol, China should phase out the production and consumption of HCFC-141b by 2030. …”
Get full text

The "conquest" of historical space in the 21st century Russia: negative historical identity? by Aurimas Švedas

“…The intellectual foundations of the "state patriotism" in the sphere of political science are such terms as "energetic superpower" and "sovereign democracy," which were used simultaneously in order to present Russia on the international stage and to provide the state regime – the vertical of power – with meaningfulness in the eyes of the inhabitants of the state. …”
Get full text

Control of Unexpected <i>Mucor lusitanicus</i> in Litchi Fruit by Hydrocooling with Hypochlorous Acid and Cold Storage by I-Fang Liu, Huey-Ling Lin, Chang-Lin Chen

“…This approach can extend the storage ability of litchi fruit while maintaining its quality, providing a safer method for local and international markets.…”
Get full text