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301
HPLC-MS/MS-Mediated Analysis of the Pharmacokinetics, Bioavailability, and Tissue Distribution of Schisandrol B in Rats
Published 2021-01-01“…For this analysis, bifendate was chosen as an internal standard (IS). A liquid-liquid extraction (LLE) approach was employed for the preparation of samples that were subsequently separated with an Agilent ZORBAX Eclipse XDB-C18 (4.6 × 150 mm, 5 μm) column with an isocratic mobile phase consisting of methanol and water containing 5 mM ammonium acetate and 0.1% formic acid (90 : 10, v/v). …”
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302
Development of an automated method for in-house production of sodium 18F-fluoride for injection: process validation as a step toward routine clinical application
Published 2025-02-01“…Process validation was carried according to GMP guidelines to ensure consistency of [18F]NaF quality with international standards. The final radiopharmaceutical met all quality criteria specified by Ph. …”
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303
HALAL INDUSTRY IN KYRGYZSTAN: CURRENT STATE AND DEVELOPMENT PROSPECTS
Published 2024-12-01“…The subject of the study are the organisational and economic mechanisms of the halal industry in the Kyrgyz Republic where the development of the halal industry relies on the basis of innovative investments by orienting themselves on international standards. The use of theoretical and practical recommendations. …”
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304
Validated UPLC-MS/MS Method for Determination of Futibatinib and Its Pharmacokinetics in Beagle Dogs
Published 2022-01-01“…After the plasma protein was removed by acetonitrile precipitation, futibatinib was detected and derazantinib was used as the internal standard (IS). Futibatinib and IS were separated in an UPLC BEH C18 column (2.1 mm × 50 mm, 1.7 μm) with acetonitrile and 0.1% formic acid as the mobile phase, and the flow rate was 0.3 mL/min. …”
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305
A Validated Volumetric Absorptive Microsampling-Liquid Chromatography Tandem Mass Spectrometry Method to Quantify Doxycycline Levels in Urine: An Application to Monitor the Malaria...
Published 2020-01-01“…The mean extraction recovery was 109% (mean RSD, 5.4%, n = 6) for doxycycline and 102% (mean RSD, 7.0%) for the internal standard. No matrix effect has been shown. Within-run as within-day precision and accuracy were, respectively, below 14% and ranged from 96 to 106%. …”
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306
Pharmacokinetics and Bioavailability Study of Tubeimoside I in ICR Mice by UPLC-MS/MS
Published 2018-01-01“…The TBMS-I and ardisiacrispin A (internal standard (IS)) were quantitatively detected by a tandem mass spectrometry equipped with an electrospray ionization (ESI) in a positive mode by multiple reaction monitoring (MRM). …”
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307
Design of An Automobile Engine Stand.
Published 2024“…By utilizing this stand, garages can enhance their engine maintenance practices to align with international standards, ultimately improving operational efficiency. …”
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308
Development and Validation of a New Method for Determination of Pb and Cr in Marine Organisms by Total Reflection X-Ray Fluorescence (TXRF) Spectroscopy
Published 2019-01-01“…In order to correct possible instrument drifts, 20 μg·L−1 of gallium was used as internal standard (IS). The results showed that TXRF method was linear over the concentration ranges of 5.242–100 μg·L−1 for Pb and 2.363–100 μg·L−1 for Cr. …”
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309
Designing and evaluating a patient decision aid for patients with locally advanced or locally recurrent rectal cancer: a national multicentre mixed methods study protocol
Published 2022-06-01“…There are no decision tools for these patients and current resources have found to not meet minimum international standards. The overall aim of this study is to produce a validated patient decision aid (PtDA) to assist patients considering radical pelvic exenteration for LARC and LRRC created in line with international minimum standards.Methods and analysis This study is a national, multicentre mixed methods project and has been designed in keeping with guidance from the International Patient Decision Aids Standard.This study is in four stages. …”
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310
Predictive Ability of Visit-to-Visit Variability of HbA1c Measurements for the Development of Diabetic Kidney Disease: A Retrospective Longitudinal Observational Study
Published 2022-01-01“…Visit-to-visit variability of HbA1c was calculated as the internal standard deviation of HbA1c (HbA1c-SD), the coefficient of variation of HbA1c (HbA1c-CV), the HbA1c change score (HbA1c-HVS), and the area under the HbA1c curve (HbA1c-AUC) with 3-year serial HbA1c measurement data, and the associations between these indices and the development/progression of DKD were examined. …”
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311
Technology Readiness Level of biodiversity monitoring with molecular methods – where are we on the road to routine implementation?
Published 2025-01-01“…Key barriers to the broader implementation of molecular methods to monitoring include the need for international standards, better quantitative estimates and comprehensive reference libraries. …”
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312
Sources of Civil and Sports Law as a sub-branch of Civil Law of Ukraine
Published 2022-06-01“…In addition, Civil and Sports Law will meet international standards, the legal status of professional athletes and other subjects of sports legal relations will become more protected, research in the field of Private Law regulation of social relations arising in the field of physical culture and sports will be intensified, it will make it possible to establish the procedure for consideration of disputes between subjects of sports legal relations more transparent.…”
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313
ECONOMIC ASPECTS OF ORGANIC SOY PRODUCTION IN UKRAINE
Published 2024-12-01“…The subject of this work is the implementation of the strategy of sustainable development in Ukraine, which is based on ensuring national interests and fulfilling international obligations, it is envisaged to overcome imbalances that exist, in particular, in the environmental sphere, the harmonisation of global climate change trends with international standards through the introduction of scientific aspects of organic soybean production. …”
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314
Perceptions and barriers to the use and training of point-of-care ultrasound among Finnish emergency physicians – a nationwide survey
Published 2025-01-01“…Conclusions The results highlight a need for reform in POCUS training in Finland, demonstrating a need for structured, competency-based educational frameworks that align with international standards. Improvements on training infrastructure, including enhanced mentorship and increased access to ultrasound equipment, are essential enablers of such a reform. …”
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315
Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs
Published 2021-01-01“…Sitagliptin was selected as the internal standard. 0.02% formic acid aqueous solution (A) and methanol-acetonitrile (B) were used as mobile phases with gradient elution at a flow rate of 0.3 mL/min. …”
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316
An initial benchmark of the quality of the diagnosis and surgical treatment of breast cancer in South Africa
Published 2025-02-01“…Rates of positive margins (5.7%), overall axillary surgery (95.8%) and appropriate treatment sequencing in locally advanced breast cancer patients (98.4%) consistently reached minimum international standards. Rates of multidisciplinary team discussion (72.2%), radiotherapy (66.7%) and sentinel node biopsy (39.6%) showed wide cross-site variance. …”
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317
Evaluation of Sharia-based Sustainability Reporting Framework Influenced by the Emergence of Metaverse Axes in Accounting
Published 2023-03-01“…By promoting jurisprudential values and Shariah standards, Islamic societies are always seeking to strengthen the level of adherence to morality, and this issue has caused many countries to consider Islamic rules in addition to international standards and laws to achieve greater legitimacy. …”
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318
Assessment of heavy metal pollution and spatial distribution in waterfalls of Chattogram district, Bangladesh: Implications for drinking and irrigation purposes
Published 2025-04-01“…The concentrations of Na, K, Ca, Mg, Fe, Mn, Cu, Cd, Hg, Cr, and As in water samples were measured by Atomic Absorption Spectrometer (AAS), and compared with the national (ECR, 2023) and international standards (WHO, 2015). Heavy Metal Pollution Index (HPI) were calculated (18.51 to 22.87) showed below the critical limit of 100, indicating suitability for drinking. …”
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319
Principles to award learning achievements for lifelong learning in health using micro-credentials: an international Delphi study
Published 2025-02-01“…Establishing international standards can ensure consistency, promote equity, and enhance quality of recognition systems. …”
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320
Analysis of antibiotic sensitivity of clinical strains of microorganisms with the Russian Mueller–Hinton broth
Published 2024-12-01“…MHB-Obolensk complies with the requirements of national and international standards and can be used to reliably test, among other things, current combinations of microorganism–antibiotic pairs that cannot be studied using the disk diffusion method.…”
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