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201
Validation of Simultaneous Quantitative Method of HIV Protease Inhibitors Atazanavir, Darunavir and Ritonavir in Human Plasma by UPLC-MS/MS
Published 2014-01-01“…The sample pretreatment consisted of solid phase extraction of analytes and their deuterated analogs as internal standards from 50 μL human plasma. Chromatographic separation of analytes was performed on Waters Acquity UPLC C18 (50 × 2.1 mm, 1.7 μm) column under gradient conditions using 10 mM ammonium formate, pH 4.0, and acetonitrile as the mobile phase. …”
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202
Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma
Published 2019-01-01“…The plasma samples containing rifampicin and isotopically labelled internal standard rifampicin D8, were cleaned up using a Captiva ND Lipids filtration plate. …”
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203
A Unique Source for Innovative Longitudinal Research: The POPLINK Database
Published 2016-03-01“…POPLINK allows for a large array of longitudinal studies, such as social mobility, migration, fertility, mortality, civil status, kinship relations, diseases, disability and causes of death. International standards of occupations (HISCO) and diseases (ICD-10) have been applied, facilitating comparability. …”
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204
Ion suppression correction and normalization for non-targeted metabolomics
Published 2025-02-01“…Here we report a method, the IROA TruQuant Workflow, that uses a stable isotope-labeled internal standard (IROA-IS) library plus companion algorithms to: 1) measure and correct for ion suppression, and 2) perform Dual MSTUS normalization of MS metabolomic data. …”
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205
Modern features of the cryptocurrency use for terrorist financing, money laundering and other unlawful activities: prospective countermeasures
Published 2023-07-01“…The author identifies the need to complete the process of legislative definition of the status and regulation of cryptocurrency circulation; to improve the national system of countermeasures, to establish coordination of the work of authorised state bodies; to ensure the implementation of international standards; to establish public-private partnership and cooperation between competent entities of Ukraine and foreign countries.…”
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206
Quantification and identification of microfibers released from textiles during simulated accelerated washing
Published 2025-03-01“…As such, in this work, fibers from different fabrics were subjected to a simulated accelerated washing process to determine the release of microfibers into the resulting water following established and defined international standards. Though there are numerous examples of scientific works delving into this subject, the present work constitutes an initial step towards the use of internationally recognized methodologies for the determination of microfibers during washing processes that, when in conjunction with other similarly carried out works, may contribute to a better understanding of the mechanisms of release of these materials during everyday activities, such as washing and drying of clothes. …”
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207
Non-discrimination and equality in healthcare: guarantees of implementation in international law and Ukrainian legislation
Published 2024-12-01“…The author emphasises the need to harmonise national legislation with international standards, which will contribute to the creation of an inclusive healthcare system. …”
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208
The Impact of Oil and Gas Resources In the Arctic on the Development of the Transport System in the Region
Published 2015-08-01“…The current state of the port system, which does not fully meet the latest international standards, is of crucial importance as well. …”
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209
Long-Term Stability of Hydromorphone in Human Plasma Frozen at −20°C for Three Years Quantified by LC-MS/MS
Published 2022-01-01“…Blood samples were disposed using solid-phase extraction with an additional substitution of stable isotope labelled hydromorphone as an internal standard. Hydromorphone concentrations were determined by ultra-performance liquid chromatography (UPLC) with gradient elution, followed by tandem mass spectrometry with electrospray ionization. …”
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210
A Unique Source for Innovative Longitudinal Research: The POPLINK Database
Published 2016-03-01“…POPLINK allows for a large array of longitudinal studies, such as social mobility, migration, fertility, mortality, civil status, kinship relations, diseases, disability and causes of death. International standards of occupations (HISCO) and diseases (ICD-10) have been applied, facilitating comparability. …”
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211
Development and Validation of a GC-MS Method for the Detection and Quantification of Clotiapine in Blood and Urine Specimens and Application to a Postmortem Case
Published 2015-01-01“…Methadone-d9 was used as internal standard. Results. The limit of detection (LOD) was 1.2 and 1.3 ng/mL for urine and blood, respectively, while the lower limit of quantification (LLOQ) was 3.9 and 4.3 ng/mL, respectively. …”
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212
CONCEPTUAL AMBUSH OF DIGITAL TRANSFORMATIONS IN THE SYSTEMS OF GOVERNMENT MANAGEMENT: WIKILEAKS TODAY
Published 2024-12-01“…The main drivers of digital transformation (technological innovations, citizens' expectations, international standards) and barriers (financial constraints, digital competence, regulatory instability) are identified. …”
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213
Characterization of Key Odorants in Soy Sauce and Their Concentration Changes during Storage
Published 2023-01-01“…The results of quantitative analysis through the internal standard curve showed that the concentrations of HEMF, HDMF, acetic acid, 1-hydroxy-2-butanone, acetol, and furfuryl alcohol varied greatly during storage, so these compounds might be used as the indicators to determine the shelf life of HLFSS. …”
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214
Key Elements in Integrity Management of Underground Gas Storage: A Framework for Energy Safety
Published 2025-01-01“…To address these issues, this study systematically analyzes domestic and international standards related to gas storage and establishes a technical system based on “three-in-one” integrity management (geological structure, wellbore, and surface facilities). …”
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215
Comprehensive Analysis of Sustainability Rating Systems for Road Infrastructure
Published 2025-01-01“…Furthermore, this study identifies notable deficiencies in the integration of critical international standards, including ISO, EN, and ASTM, which constrains the comprehensiveness and global applicability of these frameworks. …”
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216
A Unique Source for Innovative Longitudinal Research: The POPLINK Database
Published 2016-03-01“…POPLINK allows for a large array of longitudinal studies, such as social mobility, migration, fertility, mortality, civil status, kinship relations, diseases, disability and causes of death. International standards of occupations (HISCO) and diseases (ICD-10) have been applied, facilitating comparability. …”
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217
Determination of Crizotinib in Mouse Tissues by LC-MS/MS and Its Application to a Tissue Distribution Study
Published 2020-01-01“…Mouse tissue homogenates were processed by protein precipitation with methanol, and apatinib was chosen as the internal standard. The analytes were separated on a Phenomenex Kinetex C18 (50 mm × 2.1 mm, 2.6 μm) column with gradient elution using methanol and 0.3% formic acid water solution. …”
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218
Development and Validation of UPLC-MS/MS Method for Determination of Enasidenib in Rat Plasma and Its Pharmacokinetic Application
Published 2020-01-01“…In our research, a straightforward UPLC-MS/MS method, with diazepam as the internal standard (IS), was proposed and acknowledged to determine the concentrations of enasidenib in rat plasma. …”
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219
Determination of Urinary Creatinine in Washington State Residents via Liquid Chromatography/Tandem Mass Spectrometry
Published 2014-01-01“…A viable, quick, and reliable method for determining urinary creatinine by liquid chromatography/tandem mass spectrometry (LC/MS/MS) was developed and used to evaluate spot urine samples collected for the Washington Environmental Biomonitoring Survey (WEBS): part of the Washington State Department of Health, Public Health Laboratories (PHL). 50 µL of urine was mixed with a 1 : 1 acetonitrile/water solution containing deuterated creatinine as the internal standard and then analyzed by LC/MS/MS. Utilizing electrospray ionization (ESI) in positive mode, the transition ions for creatinine and creatinine-d3 were determined to be 114.0 to 44.1 (quantifier), 114.0 to 86.1 (qualifier), and 117.0 to 47.1 (creatinine-d3). …”
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220
Fine tuning enzyme activity assays for monitoring the enzymatic hydrolysis of PET
Published 2025-01-01“…For the HPLC-based assessment, the incorporation of an internal standard within the analytic procedure enabled a more accurate quantification of the overall TPA content and the assessment of molar distributions and relative content of each aromatic degradation product. …”
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