Immune responses in children with secondary infection of mycoplasma pneumoniae after COVID-19: focus on eosinophils and IgE by Pingping Wang, Jin Yao, Yaqiong Li, Zhanjun Zhang, Ruiling Zhang, Shouting Lu, Meixia Sun, Xiaorong Huang

Subjects: Get full text

Clinical significance of PCT, CRP, IL-6, NLR, and TyG Index in early diagnosis and severity assessment of acute pancreatitis: A retrospective analysis by Xu Xinyu, Zhou Jiang, Ai Qing, Li Lihua, Liu Xiehong, Zhou Lin

Subjects: Get full text

Characterisation of IGF-1 (rs7136446) and IL-6 (rs1800795) polymorphisms among breast cancer patients in western Algeria by Fatima Zohraa Boussouf, Asmahane Medjdoub, Zineb Tahari, Moussa Messatfa, Noria Bouras, Chahinez Amira Dahmani, Sonia Amal Seddiki, Tewfik Sahraoui

Subjects: Get full text

Low-grade systemic inflammation, but not neuroinflammation, is associated with 12-month postoperative outcome after total hip arthroplasty in patients with painful osteoarthritis:... by Morten R. Blichfeldt-Eckhardt, Claus Varnum, Jørgen T. Lauridsen, Lasse E. Rasmussen, Winnie C. P. Mortensen, Hanne I. Jensen, Henrik B. Vaegter, Kate L. Lambertsen

Subjects: Get full text

Multimodal low-opioid anesthesia as a factor in reducing the activation of the proinflammatory response in cardiac surgery by S.R. Maruniak, O.A. Loskutov, O.M. Druzhyna, I.R. Malysh, V.G. Kolesnikov, N.O. Korotchuk

“…The aim – to evaluate the effect of the low opioid anesthetic management scheme on the dynamics of cytokines (interleukin-6) during coronary artery bypass grafting (CABG). …”
Get full text

Cytokines in Liver Cirrhosis (Their Importance in Assessing Activity and Decompensation) by G. K. Mirodzhov, S. D. Pulatova

“…In patients with Class B liver cirrhosis, the level of TNF-α increased to 75.0 ± 4.5 pg/mL (p < 0.001), interleukin-2 — to 328.7 ± 23.9 pg/mL (p < 0.05), and interleukin-6 — to 95.4 ± 7.7 pg/mL (p < 0.001). Serum interleukin-10 decreased compared with the control group (23.1 ± 2.8 pg/mL; p > 0.05). …”
Get full text

Effects of ursolic acid on growth performance, serum biochemistry, antioxidant capacity, and intestinal health of broilers by X.W. Zhang, X. Li, Y. Yin, M. Wang, Y.F. Wang, J.Y. Chen, Y.R. Zhao

“…Barnesiella negatively correlated with interleukin 6, interleukin 1, and triacylglycerol, but positively correlated with interleukin 10 (P < 0.05). …”
Get full text

HSV-1 miR-H6 Inhibits HSV-1 Replication and IL-6 Expression in Human Corneal Epithelial Cells In Vitro by Fang Duan, Jingyu Liao, Qiang Huang, Yuhong Nie, Kaili Wu

“…In addition, miR-H6 can decrease the interleukin 6 released into the medium, which was determined by ELISA. …”
Get full text

A Case of Rheumatoid Arthritis and Limited Systemic Sclerosis Overlap Successfully Treated with Tocilizumab for Arthritis and Concomitant Generalized Lymphadenopathy and Primary Bi... by Eiko Saito, Shinji Sato, Shinichi Nogi, Noriko Sasaki, Naofumi Chinen, Kiri Honda, Takayuki Wakabayashi, Chiho Yamada, Naoya Nakamura, Yasuo Suzuki

“…This suggested that interleukin-6 might play an important role in reactive lymphadenopathy and PBC associated with RA/lSSc.…”
Get full text

e-Cadherin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson Disease by Samuela Cataldi, Michela Codini, Stéphane Hunot, François-Pierre Légeron, Ivana Ferri, Paola Siccu, Angelo Sidoni, Francesco Saverio Ambesi-Impiombato, Tommaso Beccari, Francesco Curcio, Elisabetta Albi

“…We used 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a neurotoxin that induces Parkinson disease, to evaluate the change of midbrain structure and the behavior of the anti-inflammatory factor e-cadherin, interleukin-6, tyrosine hydroxylase, phosphatase and tensin homolog, and caveolin-1. …”
Get full text

Clinical characteristics and usage of statins in patients with stable ischemic heart disease referred for angiography or coronary artery bypass grafting by I.V. Shklianka, O.J. Zharinov, К.O. Mikhaliev, O.A. Epanchintseva

“…No statin therapy was associated with higher levels of total cholesterol and interleukin-6 compared with the group of patients taking statins (total cholesterol, respectively, 4.8 versus 4.2 mmol/l (p = 0.016) and interleukin-6, respectively, 4.4 versus. 3.1 p/ml (p = 0.022)). …”
Get full text

Idiopathic Multicentric Castleman Disease following SARS-CoV-2 Vaccination by Chien-Yu Ker, Hung-Wei Liu, Yu-Chieh Su, Pang-Yu Lai*

“…The preferred primary treatment for iMCD is siltuximab, an anti-interleukin-6 antibody (anti–IL-6). Chemotherapy is reserved for severe cases or when anti-IL-6 is unavailable. …”
Get full text

The effect of SARS-CoV-2 Omicron BA. 5.2 infection on perioperative physiological indicators in orthopedic patients by Hao Wu, JunZhe Yang, YuQin Yan, Xiao Hu, BiXi Li, PengFei Cheng, XiaoYang Song

“…Results Heart rate, mean arterial pressure, oxygenation index, NLR, PLR, SII, interleukin-6 and calcitonin were similar between the two groups (P > 0.05). …”
Get full text

Tocilizumab Was Effective in Repairing the Large Geode in a Patient with Rheumatoid Arthritis by Takuya Izumiyama, Yu Mori, Eiji Itoi

“…The present report shows the significant effect of interleukin-6 receptor blocker, tocilizumab, in repairing the large geode in the left humeral lateral epicondyle. …”
Get full text

Curdlan sulphate modulates protein synthesis and enhances NF-κB and C/EBP binding activity in HepG2 cells by A. Guzdek, H. Rokita

“…In human hepatoma HepG2 cell line curdlan sulphate enhances basal and interleukin-6-stimulated fibrinogen and antichymotrypsin (ACT) synthesis, slightly increases basal ceruloplasmin production and exerts only minor effects on alpha-1-proteinase inhibitor and transferrin. …”
Get full text

Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells by E. Jablonskaca, W. Puzewska, M. Marcinczyk, J. Jablonski

“…Background: In our previous study we found that rhsIL-6R, along with recombinant human interleukin-6, plays a regulatory role in the immune response by modulating the tumour necrosis factor-α (TNF-α) expression and its production by peripheral blood mononuclearcells (PBMC). …”
Get full text

Superior liver protection in mice fed total parenteral nutrition containing the novel lipid emulsion Vegaven as compared to a mixed-oil lipid emulsion containing fish oil by Eliana Lucchinetti, Phing-How Lou, Alessandro Quaranta, Craig E. Wheelock, Akash Chakravarty, Martin Hersberger, Stefanie D. Krämer, Michael Zaugg

“…Tumor necrosis factor alpha and interleukin-6 (IL6) tissue concentrations were increased in livers of mice in the SMOF group and interleukin-6 (IL6) to interleukin-10 (IL10) ratios were lower in livers and epididymal white adipose tissue of mice in the VEGA group. …”
Get full text

Purpuric pityriasis rosea in patients with anorexia nervosa by Giulia Ciccarese, Antonio Guadagno, Astrid Herzum, Valentina Amicarelli, Francesco Drago

“…Furthermore, an increased level of the vascular cell adhesion molecule 1, interleukin 6, and tumor necrosis factor-α has been demonstrated in AN patients, which may be responsible for their increased vascular dysfunction. …”
Get full text

TAFRO Syndrome Mimicking Solid Cancer and Successfully Treated by Tocilizumab: A Case and Literature Review by Pei-An Fu, Chia-Chi Wu, Ya-Ting Hsu

“…Hypersecretion of pro-inflammatory cytokines, such as interleukin-6, plays a critical role in this disease. …”
Get full text

Metallothionein-3-mediated intracellular zinc mediates antioxidant and anti-inflammatory responses in the complete Freund’s adjuvant-induced inflammatory pain mouse model by Ngoc Buu Tran, Sook-Jeong Lee

“…Furthermore, intracellular Zn2+ was crucial in regulating oxidative stress markers (glutathione, superoxide dismutase, catalase, and malondialdehyde) and inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6, in MT3 knockout mice induced with CFA. …”
Get full text