Interleukin-6 “Trans-Signaling” and Ischemic Vascular Disease: The Important Role of Soluble gp130 by Mario Luca Morieri, Angelina Passaro, Giovanni Zuliani

“…Inflammation plays a major role in the onset of cardiovascular disease (CVD). Interleukine-6 (IL-6) is a multifunctional cytokine involved both in the beneficial acute inflammatory response and in the detrimental chronic low-grade systemic inflammation. …”
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The role of interleukin-6 classic and trans-signaling and interleukin-11 classic signaling in gastric cancer cells by Josephine Runge, Christoph Garbers, Juliane Lokau

Subjects: “…interleukin-6…”
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Systemic Factors Related to Intraocular Levels of Interleukin-6 and Vascular Endothelial Growth Factor in Diabetic Retinopathy by Byung Ju Jung, Mee Yon Lee, Sohee Jeon

“…This study is for identifying systemic factors correlating with intraocular levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) in diabetic retinopathy. …”
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Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models by Carol Milligan, Dale O. Cowley, William Stewart, Alyson M. Curry, Elizabeth Forbes, Brian Rector, Annette Hastie, Liang Liu, Gregory A. Hawkins

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A Case of Squamous Cell Carcinoma of the Lung That Produced Granulocyte Colony-Stimulating Factor and Interleukin-6 by Nobuhiro Takeuchi, Kento Yamamoto, Kazuyoshi Naba

“…Immunohistochemical examination of biopsy specimens showed positive staining with antigranulocyte colony-stimulating factor and anti-interleukin-6 monoclonal antibodies. Diagnosis of a tumor that produced granulocyte colony-stimulating factor and interleukin-6 was established. …”
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Effect of Exercise Training on Interleukin-6, Tumour Necrosis Factor Alpha and Functional Capacity in Heart Failure by Neil A. Smart, Alf I. Larsen, John P. Le Maitre, Almir S. Ferraz

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The potential utility of synovial C-reactive protein, interleukin-6, and presepsin in diagnostics of periprosthetic joint infection by Lyudmila V. Lyubimova, Svetlana I. Pavlova, Nikolay S. Nikolaev, Evgeniy A. Lyubimov, Nadezhda N. Pchelova, Vladimir Y. Emelianov

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Intraoperative dynamics of interleukin-6 levels during planned coronary stenting with different approaches to analgesic sedation by D.О. Dziuba

Subjects: “…interleukin-6…”
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Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells by Liza U. Ljungberg, Mulugeta M. Zegeye, Caroline Kardeby, Knut Fälker, Dirk Repsilber, Allan Sirsjö

“…Background. Interleukin 6 (IL6) is a multifunctional cytokine produced by various cells, including vascular endothelial cells. …”
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Use of Anti-Interleukin-6 Receptor Monoclonal Antibody in Drug-Induced Acute Respiratory Distress Syndrome by Alessandra Petrillo, Noa Biran, Sean Sadikot

“…We discuss a case of a patient with multiple myeloma who was hospitalized with drug-induced ARDS who had a rapid response to an anti-interleukin-6 monoclonal antibody.…”
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Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case–control study by Elif Baris, Izel Topaloglu, Elif Akalin, Emre Hamurtekin, Seray Kabaran, Ayse Gelal, Reyhan Ucku, Mualla Aylin Arici

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The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review by Theodoros Karampitsakos, Despoina Mavrogianni, Nikolaos Machairiotis, Anastasios Potiris, Periklis Panagopoulos, Sofoklis Stavros, Panos Antsaklis, Peter Drakakis

Subjects: “…interleukin-6 (IL-6)…”
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Circulating Interleukin-6 (but Not Other Immune Mediators) Associates with Criteria for Fried’s Frailty among Very Old Adults by Gilberto Santos Morais Junior, Diego Ignacio Valenzuela Perez, Audrey Cecília Tonet-Furioso, Lucy Gomes, Karla Helena Coelho Vilaça, Vicente Paulo Alves, Clayton Franco Moraes, Otávio Toledo Nóbrega

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Evaluation of Serum Levels of Interleukins 6, 8, 17 and 22 in Acne Vulgaris: A Cross-Sectional Study by Mahmood D. Al-Mendalawi

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Mast Cell Degranulation Decreases Lipopolysaccharide-Induced Aortic Gene Expression and Systemic Levels of Interleukin-6 In Vivo by Jason M. Springer, Vineesh V. Raveendran, Mingcai Zhang, Ryan Funk, Donald D. Smith, Mehrdad Maz, Kottarappat N. Dileepan

“…Mast cells play an important role in immunomodulation and in the maintenance of vascular integrity. Interleukin-6 (IL-6) is one of the key biomarkers and therapeutic target in systemic vasculitis. …”
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Age-dependent differences in the association between blood interleukin-6 levels and mortality in patients with sepsis: a retrospective observational study by Takashi Shimazui, Takehiko Oami, Tadanaga Shimada, Keisuke Tomita, Taka-aki Nakada

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IL-6 and PD-1 antibody blockade combination therapy regulate inflammation and T lymphocyte apoptosis in murine model of sepsis by Song I Lee, Na Young Kim, Chaeuk Chung, Dongil Park, Da Hyun Kang, Duk Ki Kim, Min-Kyung Yeo, Pureum Sun, Jeong Eun Lee

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IL-6–174 G/C transversion might decrease male infertility risk: A case-control study by Tayyebeh Zamani-Badi, Mohammad Karimian, Javad Amini Mahabadi, Atieh Rafatmanesh, Hossein Nikzad

Subjects: “…Polymorphism, Genetic, Interleukin-6, Spermatogenesis, Male infertility.…”
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Impact of diabetes mellitus on dental implants: A cross sectional controlled clinical study. by Rezhna Muhammed Hamad-Ameen, Othman Abu-Bakr Omer

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Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts by Tino Stauber, Greta Moschini, Amro A Hussien, Patrick Klaus Jaeger, Katrien De Bock, Jess G Snedeker

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