Activins and Follistatin in Chronic Hepatitis C and Its Treatment with Pegylated-Interferon-α Based Therapy by Bassem Refaat, Ahmed Mohamed Ashshi, Adel Galal El-Shemi, Esam Azhar

“…Pegylated-interferon-α based therapy for the treatment of chronic hepatitis C (CHC) is considered suboptimal as not all patients respond to the treatment and it is associated with several side effects that could lead to dose reduction and/or termination of therapy. …”
Get full text

12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γ Counterregulated-Mediator of Allergic Airway Inflammation by Alexa R. Lindley, Margaret Crapster-Pregont, Yanjun Liu, Douglas A. Kuperman

“…Interleukin-13 and interferon-γ are important effectors of T-helper cells. …”
Get full text

Newer Clinical Strategies for Combining Interferon and Cytotoxic Agents Against Solid Tumours and Hematological Malignancies by Scott Wadler

“…The role of interferons in the treatment of cancer continues to evolve. …”
Get full text

Onset of Celiac Disease after Treatment of Chronic Hepatitis C with Interferon Based Triple Therapy by Amandeep Singh, Nayere Zaeri, Immanuel K. Ho

“…Patients treated with interferon (IFN) based therapies may develop exacerbation of autoimmune disease. …”
Get full text

Is Combined Bulevirtide and Pegylated Interferon Therapy for Chronic Hepatitis D Superior over Bulevirtide Monotherapy? by V. E. Syutkin, A. O. Bueverov, P. O. Bogomolov

Subjects: Get full text

Type I Interferon at the Interface of Antiviral Immunity and Immune Regulation: The Curious Case of HIV-1 by Adriano Boasso

“…Type I interferon (IFN-I) play a critical role in the innate immune response against viral infections. …”
Get full text

In vitro interleukin 4 and interferon-gamma production by mononuclear cells from atopic dermatitis patients by Serge Well, Friedhelm Diel

“…In order to elucidate further the possible role of specific cytokines in the pathogenesis of atopic dermatitis (AD) the in vitro production of interleukin 4 (IL-4) and interferon-gamma (IFN-γ) in patients with severe atopic dermatitis (n = 4) was compared with that in a group of non-atopic healthy controls. …”
Get full text

MHC Class I Molecules Exacerbate Viral Infection by Disrupting Type I Interferon Signaling by Simo Xia, Yijie Tao, Likun Cui, Yizhi Yu, Sheng Xu

Get full text

Budding of Enveloped Viruses: Interferon-Induced ISG15—Antivirus Mechanisms Targeting the Release Process by Eun Joo Seo, Jonathan Leis

Get full text

Russian interferon <i>α</i>-2b drug in the treatment of chronic hepatitis C by N. B. Kovaleva

“…To study efficacy and safety of domestic recombinant interferon α-2b Altevir® in combination to ribavirin in previously untreated patients with chronic hepatitis C (CHC).Material and methods. …”
Get full text

Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity by Dyah Ika Krisnawati, Yung-Ching Liu, Yuarn-Jang Lee, Yun-Ting Wang, Chia-Ling Chen, Po-Chun Tseng, Ting-Jing Shen, Chiou-Feng Lin

“…The interferon- (IFN-) γ expression is elicited in response to microbial infections and activates immune surveillance by antimicrobial immune elements to induce microbial killing. …”
Get full text

Successful treatment of life-threatening mycobacteriosis using adjunctive gamma-interferon therapy with genetic analysis by P. Confalonieri, S. Maiocchi, F. Salton, B. Ruaro, C. Rizzardi, M. C. Volpe, D. Licastro, L. Braga, M. Confalonieri

Get full text

Discovery of a non‐nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect by Xiyuan Wang, Zhengsheng Zhan, Zhen Wang, Yan Zhang, Kaiyan Zhao, Han Li, Xiaoqian Zhou, Yuting Guo, Fengying Fan, Jian Ding, Meiyu Geng, Xuekui Yu, Wenhu Duan, Zuoquan Xie

“…Abstract Agonists of the stimulator of interferon genes (STING) pathway are increasingly being recognized as a promising new approach in the treatment of cancer. …”
Get full text

Pegilated interferon alpha 2b «Pegaltevir» chronic hepatitis C treatment (randomized clinical trial) by Marina V. Mayevskaya, Ye. N. Bessonova, P. O. Bogomolov, N. I. Geyvandova, K. V. Zhdanov, V. G. Morozov, V. D. Pasechnikov, I. Yu. Khomenko, A. V. Yagoda, V. T. Ivashkin

“…Nowadays the question, whether pegylated interferon should be completely abandoned in the treatment of chronic hepatitis C (CHC) is still open. …”
Get full text

Levels of Interferon-Gamma Increase after Treatment for Latent Tuberculosis Infection in a High-Transmission Setting by Iukary Takenami, Brook Finkmoore, Almério Machado, Krisztina Emodi, Lee W. Riley, Sérgio Arruda

Get full text

Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C by Louis WC Liu, George Tomlinson, Tony Mazzulli, Alison Murray, Jenny Heathcote

“…BACKGROUND: Treatment of chronic hepatitis C virus (HCV) infection with interferon alpha-2b and ribavirin is costly in terms of side effects, medical resources and drug costs. …”
Get full text

The efficiency of interferon stimulated gene 15 expression in peripheral blood for early pregnancy prediction in Awassi ewes by Eman H. Lazim, Khawla A. Hussein, Dhafer M. Aziz

“…This study was designed to identify the efficiency of interferon-stimulated gene 15 (ISG15) expression for early pregnancy detection in Awassi ewes. …”
Get full text

The Role of Interferon Regulatory Factor-1 (IRF1) in Overcoming Antiestrogen Resistance in the Treatment of Breast Cancer by J. L. Schwartz, A. N. Shajahan, R. Clarke

“…While the mechanisms that regulate endocrine responsiveness and cell fate are not fully understood, interferon regulatory factor-1 (IRF1) is strongly implicated as a key regulatory node in the underlying signaling network. …”
Get full text

TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms by Nicholas L. Calistri, Tiera A. Liby, Zhi Hu, Hongmei Zhang, Mark A. Dane, Sean M. Gross, Laura M. Heiser

Subjects: Get full text

Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells by Alexia Carré, Fatoumata Samassa, Zhicheng Zhou, Javier Perez-Hernandez, Christiana Lekka, Anthony Manganaro, Masaya Oshima, Hanqing Liao, Robert Parker, Annalisa Nicastri, Barbara Brandao, Maikel L. Colli, Decio L. Eizirik, Jahnavi Aluri, Deep Patel, Marcus Göransson, Orlando Burgos Morales, Amanda Anderson, Laurie Landry, Farah Kobaisi, Raphael Scharfmann, Lorella Marselli, Piero Marchetti, Sylvaine You, Maki Nakayama, Sine R. Hadrup, Sally C. Kent, Sarah J. Richardson, Nicola Ternette, Roberto Mallone

“…Abstract Interferon (IFN)-α is the earliest cytokine signature observed in individuals at risk for type 1 diabetes (T1D), but the effect of IFN-α on the antigen repertoire of HLA Class I (HLA-I) in pancreatic β-cells is unknown. …”
Get full text