Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

“…Additionally, we identified a synergistic drug combination involving tipifarnib and a ferroptosis inducer and discovered PTP4A1 as a regulator of interferon signaling. Our data, covering 15,080 proteins, offer valuable insights for future studies of farnesylation and FTIs.…”
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Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma by Christina Draijer, Patricia Robbe, Carian E. Boorsma, Machteld N. Hylkema, Barbro N. Melgert

“…M1, M2, and M2-like phenotypes were identified by interferon regulatory factor 5 (IRF5), YM1, and IL-10, respectively. …”
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Inflammatory proteins related to depression in multiple sclerosis: A systematic review and meta-analysis by L.A. Kiropoulos, V. Rozenblat, N. Baes

“…Results: Fifteen studies involving measurements of inflammatory proteins and level of depression in 1102 individuals with MS were included in the meta-analysis: five for interleukin (IL)-10 (LPS and PHA), four for tumour necrosis factor (TNF)-α, four for interferon (IFN)-γ, and four for IL-6 (LPS and PHA). …”
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Immunomodulatory effect of hepatitis B virus (HBV) antigens and MRSA antigens on immune response by Entidhar A. Hadi, Mohammad Abd-Kadhum Al-Saadi, Kaiser N. Madlum

“…The immune response against MRSA somatic antigens was assessed by measurement of interferon-γ, interleukin-4, and interleukin-5 by enzyme-linked immunosorbent assay technique. …”
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Serum chemokine IL-8 acts as a biomarker for identifying COVID-19-associated persistent severe acute kidney injury by Zhi He, Jing-jing Liu, Shao-lei Ma

“…Cytometric Bead Array was used to detect patient plasma levels (interleukin-8 (IL-8), C-C chemokine ligand 5 (CCL5), chemokine (C-X-C Motif) ligand 9 (CXCL9), and interferon-inducible protein 10 (IP-10)) of chemokines within 24 h of enrollment.Results Of the 115 COVID-19 patients with stage 2/3 AKI, 27 were diagnosed with PS-AKI. …”
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Stevens-Johnson Syndrome and Erythema Multiforme Induced by Imiquimod 5% Cream by Ilaria Salvi, Ilaria Trave, Riccardo Castelli, Aurora Parodi, Emanuele Cozzani

“…Conclusions: We hypothesize a possible role of interferon-γ, a cytokine involved in the pathogenesis of both herpes-associated erythema multiforme and Stevens-Johnson syndrome, which is released in response to the administration of imiquimod. …”
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Noncanonical IFN Signaling, Steroids, and STATs: A Probable Role of V-ATPase by Howard M. Johnson, Ezra Noon-Song, Chulbul M. Ahmed

“…JAK1 and JAK2 activate STAT1 in the cytoplasm at the heterodimeric gamma interferon (IFNγ) receptor, while JAK1 and TYK2 activate STAT1 and STAT2 at the type I IFN heterodimeric receptor. …”
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Cortistatin-14 Exerts Neuroprotective Effect Against Microglial Activation, Blood-brain Barrier Disruption, and Cognitive Impairment in Sepsis-associated Encephalopathy by Qiang Wen, Qian Ding, Jinchao Wang, Yanhua Yin, Shangchen Xu, Yuanrong Ju, Hongsheng Ji, Bin Liu

“…In addition, cortistatin-14 treatment decreased the levels of various inflammatory cytokines, including interleukin-1β, interleukin-6, interferon-γ, and tumor necrosis factor-α in both the serum and brain of septic mice. …”
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Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction by Jingyi Tan, Anna Dai, Lai Pan, Lan Zhang, Zhongxiu Wang, Ting Ke, Weilian Sun, Yanmin Wu, Pei-Hui Ding, Lili Chen

“…Our study is aimed at exploring the effect of inflamm-aging-related cytokines of interleukin-17 (IL-17) and interferon-γ (IFN-γ) on osteoclastogenesis in vitro and periodontal destruction in vivo. …”
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Effects of Chenpi (Citrus reticulata cv. Chachiensis) on serum antioxidant enzymes, inflammatory factors, and intestinal health in Beagle dogs by Wencan Wang, Ling Xu, Yan Zhang, Yong Cao, Yixue Yang, Guo Liu, Guo Liu, Xin Mao

“…The research evidenced a notable increase in serum superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activity in dogs, accompanied by a decrease in malondialdehyde (MDA), interleukin-8 (IL-8), and interferon-gamma (IFN-γ) level. Additionally, CPP increased fecal scores and significantly reduced fecal odors due to inhibition of 3-methylindole, hydrogen sulfide (H2S), and ammonia nitrogen (NH4+-N), and also raised the levels of fecal secretory immunoglobulin A (SIgA). …”
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Anti-Inflammatory Effects of Artemisia Leaf Extract in Mice with Contact Dermatitis In Vitro and In Vivo by Chanyong Yun, Youngchul Jung, Wonjoo Chun, Beodeul Yang, Junghyun Ryu, Chiyeon Lim, Jung-Hoon Kim, Hyungwoo Kim, Su-In Cho

“…ALE prevented epidermal hyperplasia and infiltration of immune cells and lowered the production of interferon- (IFN-) gamma (γ), tumour necrosis factor- (TNF-) alpha (α), and interleukin- (IL-) 6 in inflamed tissues. …”
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Discovering the anti-parasitic activity of melatonin loaded lecithin/chitosan nanoparticles against giardiasis and cryptosporidiosis in Balb/c infected mice by Mohamed Nasser, Mona B. Abd El-atif, Habiba Alaa, Mariam Abdelaziz, Mariam Mustafa, Mustafa Masour, Salma Magdy, Salma Mohsen, Yomna El Karamany, Alyaa Farid

“…Moreover, mice of group V, which received Mel-LCNP treatment, exhibited significantly normal levels of interleukin-4 (IL-4) and interferon-gamma (IFN-γ) as well as healthy control mice group (group I). …”
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Association between Serum Neopterin and Inflammatory Activation in Chronic Kidney Disease by Ashok Kumar Yadav, Vinod Sharma, Vivekanand Jha

“…We also estimated highly sensitive CRP (hsCRP) and interluekin-6 (IL-6), tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in the CKD subjects. All assays were done using commercially available ELISA kits. …”
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Respuesta inmune en la infección por el virus del Ébola by Alain Alonso Remedios, Maité Pérez Cutiño, Daynelis Pardo Martínez, Yasmina Piloto Orraca, Blayser Ojeda Martínez, Randy Casenave-Cambet Ramírez

“…Por otro lado, este virus es resistente a los efectos antivirales del interferón tipo I, promueve la síntesis de citoquinas proinflamatorias e induce la apoptosis de los monocitos y los linfocitos. …”
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Screening of household contacts for TB infection in Cote d'Ivoire by R. K. N’Guessan, D. A. B. Orsot, J.M. Ahui Brou, N. K. Bamba, M. E. Tchoutedjem Mefo, A. S. Bakayoko

“…OBJECTIVE: Cost-benefit analysis of TB infection (TBI) screening of household contacts in Côte d’Ivoire to evaluate economic implications of the implementation of interferon-gamma release assays (IGRAs) and the tuberculin skin test (TST). …”
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Atractylenolide I prevents acute liver failure in mouse by regulating M1 macrophage polarization by Hui Zhang, Min Gao, Haiyan Wang, Junfeng Zhang, Lin Wang, Guanjun Dong, Qun Ma, Chunxia Li, Jun Dai, Zhihua Li, Fenglian Yan, Huabao Xiong

“…In vitro experiments with bone marrow-derived macrophages indicate that ATR-I regulates macrophage polarization through the mitogen-activated protein kinase (MAPK) and interferon regulatory factor (IRF) signaling pathways. …”
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Anti-inflammatory effect of Plantago asiatica crude extract in rat gout arthritis model by Bingjun Qian, Jun Hu, Li Dai, Yue Zhou, Haixia Xu

“…In comparison to in control rats, MSU induced joint space narrowing, ankle joint swelling, and increased levels of pro-inflammatory interleukin (IL)-1β, IL-17a, tumor necrosis factor (TNF)-α, and interferon (IFN)-γ, and reductions in anti-inflammatory IL-10 in the blood. …”
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Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis by Wenchang Yang, Yaxin Wang, Peng Zhang, Tao Wang, Chengguo Li, Xin Tong, Xiangyu Zeng, Yuping Yin, Kaixiong Tao, Ruidong Li

“…Moreover, OI effectively inhibited the expression of proinflammatory cytokines including interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), and IL-1β induced by Con A. …”
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Blood molecular subtypes to guide precision treatment strategies in systemic juvenile idiopathic arthritis by In-Woon Baek, Jung Woo Rhim, Kyung-Su Park, Ki-Jo Kim

“…C2 and C3 have higher levels of interferon-stimulated signatures. In a canakinumab-treated dataset, treatment response was correlated with IL1B expression and NF-κB signaling pathway, and neutrophil activation-associated processes were effectively suppressed in a good responder group. …”
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Association between serum levels of 12 different cytokines and short-term efficacy of chemoradiotherapy in esophageal squamous cell carcinoma by Yaping Zhang, Qiufeng Qi, Ming Zhu, Yun Peng, Yanqing Bao, Jun Liu, Yanzhi Bi, Min Xiao, Shaohua Chi, Yongping Liu

“…Elevated baseline levels of IL-8 and interferon-gamma (IFN-γ) were correlated with a poorer prognosis. …”
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