Recurrent Pericarditis, an Unexpected Effect of Adjuvant Interferon Chemotherapy for Malignant Melanoma by Farhan Ashraf, Fady Marmoush, Muhammad Ismail Shafi, Ashish Shah

“…We present a case of a young female with recurrent pericarditis due to interferon therapy. The role of interferon in adjuvant chemotherapy is well known and yields good effect, but this case highlights the very uncommon phenomena of interferon induced pericarditis and the significant distress it can cause.…”
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Cholinoceptor Activation Subserving the Effects of Interferon Gamma on the Contractility of Rat Ileum by Enri S. Borda, Leonor Sterin-Borda, Martin Rodriguez, Maria M. E. de Bracco

“…Recombinant rat interferon γ stimulated the contractility of isolated rat ileum at doses of 4–12 units/ml. …”
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Roles of Interferons in Pregnant Women with Dengue Infection: Protective or Dangerous Factors by Hao Zhang, Zhiyi He, Wenting Zeng, Hong-Juan Peng

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The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy by Janina Bruening, Bettina Weigel, Gisa Gerold

“…The human interferon (IFN) response is a key innate immune mechanism to fight virus infection. …”
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Inhibitory effect of interferon-beta on mouse spleen-derived mast cells by S. Konno, M. Adachi, K. Asano, K. Okamoto, T. Takahashi

“…Preparations of murine recombinant interferon (Mu-rIFN)-alpha, -beta and -gamma were assessed for their influence on in vitro growth of mast cells from normal mouse spleen cells (Sp C). …”
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Interferon Tau Affects Mouse Intestinal Microbiota and Expression of IL-17 by Wenkai Ren, Shuai Chen, Liwen Zhang, Gang Liu, Tarique Hussain, Xiao Hao, Jie Yin, Jielin Duan, Bie Tan, Guoyao Wu, Fuller W. Bazer, Yulong Yin

“…This study was conducted to explore the effects of interferon tau (IFNT) on the intestinal microbiota and expression of interleukin 17 (IL-17) in the intestine of mice. …”
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An overview of the human immune system and the role of interferon regulatory factors (IRFs) by Ashwinder Kaur, Chee-Mun Fang

“…To deploy effective immune responses, immune systems comprise various cells and molecules that communicate with each other via signaling pathways coordinated by gene regulatory networks. The interferon regulatory factors (IRFs) are critical regulators of both the immune system’s development and activation of different cells. …”
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Manipulation of Type I Interferon Signaling by HIV and AIDS-Associated Viruses by Buyuan He, James T. Tran, David Jesse Sanchez

“…Type I Interferons were first described for their profound antiviral abilities in cell culture and animal models, and later, they were translated into potent antiviral therapeutics. …”
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Retreatment with Pegylated Interferon Alpha-2a and Ribavirin in Patients with Chronic Hepatitis C Who Have Relapsed or Not Responded to a First Course of Pegylated Interferon-Based Therapy by Eric M Yoshida, Morris Sherman, Vincent G Bain, Curtis L Cooper, Marc Deschênes, Paul J Marotta, Samuel S Lee, Mel Krajden, Helga Witt-Sullivan, Robert J Bailey, Christopher Usaty, Kevork Peltekian, the Canadian Pegasys Study Group

“…BACKGROUND: Pegylated interferon (pegIFN) and ribavirin combination therapy remains the first-line treatment for chronic hepatitis C virus (HCV) infection. …”
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Chemical tools to define and manipulate interferon-inducible Ubl protease USP18 by Griffin J. Davis, Anthony O. Omole, Yejin Jung, Wioletta Rut, Ronald Holewinski, Kiall F. Suazo, Hong-Rae Kim, Mo Yang, Thorkell Andresson, Marcin Drag, Euna Yoo

“…Abstract Ubiquitin-specific protease 18 (USP18) is a multifunctional cysteine protease primarily responsible for deconjugating the interferon-inducible ubiquitin-like modifier ISG15 from protein substrates. …”
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Intensive Farmaco- Surveillance of Interferon Alpha 2b Recombinant in Multiple Sclerosis. by Leslie Pérez Ruiz, Ana María Ramos Cedeño, José Cabrera Gómez, Nancy Echazábal Santana, Hailen Bobillo López

Subjects: “…interferón-alfa 2b…”
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Reversible Pulmonary Arterial Hypertension Associated with Interferon-Beta Treatment for Multiple Sclerosis by E Gibbons, S Promislow, RA Davies, G Chandy, DJ Stewart, V Contreras-Dominguez, C Pugliese, R Dunne, LM Mielniczuk

“…Interferon (IFN) therapy has an important role in the treatment of multiple sclerosis and chronic hepatitis C infection. …”
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Interferon-Stimulated Genes and Immune Metabolites as Broad-Spectrum Biomarkers for Viral Infections by Chien-Hsin Huang, Maudry Laurent-Rolle, Tyler L. Grove, Jack Chun-Chieh Hsu

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Autologous Enhancement by Interferon of Natural Killer Activity of Human Peripheral Blood Lymphocytes by S. B. Cheknev, Y. G. Ashmanova, A. D. Pritsker, O. L. Latysheva, F. I. Yershov, A. J. Kulberg

“…The in vitro action of interferon (IFN)-α and IFN-γ from six healthy donors and ten patients with multiple sclerosis (MS) on natural killer (INK) activity of peripheral blood lymphocytes (PBL) was studied in an autologous system. …”
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Acute Hepatitis Induced by Alpha-Interferon in a Patient with Chronic Hepatitis C by Ivan Kraus, Dinko Vitezic

“…Hepatic adverse effects occur very rarely with alpha-interferon therapy. A case of acute hepatitis induced by alpha-interferon in a 33-year-old man with chronic hepatitis C is described. …”
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Treatment of Chronic Viral Hepatitis with Alpha-Interferon: A Consensus Conference Report by The CASL Hepatitis Consensus Group

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Vitiligo in a Patient Treated with Interferon Alpha-2a for Behçet’s Disease by Esra Guney, Gulunay Akcali, Betul Ilkay Akcay, Cihan Unlu, Gurkan Erdogan, Tahir Kansu Bozkurt, Huseyin Bayramlar

“…Behçet’s disease (BD) and vitiligo are diseases of unknown etiology. Interferon (IFN) alpha therapy is commonly used in Behçet uveitis. …”
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Impact of interferon-free regimens in patients with chronic HCV and successfully ablated HCC by Amr Maged Mahmoud Rasheed, Maissa E. L. Raziky, Mohammad El Sayed, Mai Mehrez, Gamal Esmat

“…Aim of the work This study aimed to ascertain the sustained virological response (SVR) to interferon-free regimens in chronic people with HCV after the successful treatment of hepatocellular carcinoma, as well as the percentage of persons who would demonstrate any radiological or laboratory alterations indicating a local or de novo recurrence of HCC. …”
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Potential Involvement of Type I Interferon Signaling in Immunotherapy in Seasonal Allergic Rhinitis by Lina Mattson, Antonio Lentini, Danuta R. Gawel, Tejaswi V. S. Badam, Mikael Benson, Torbjorn Ledin, Colm E. Nestor, Mika Gustafsson, Jordi Serra-Musach, Janne Bjorkander, Zou Xiang, Huan Zhang

“…Recent studies report type I interferons shifting the balance between type I T helper cell (Th1) and type II T helper cells (Th2) towards Th2 dominance by inhibiting the differentiation of naive T cells into Th1 cells. …”
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Irreversible Anterior Ischemic Optic Neuropathy Complicating Interferon Alpha and Ribaverin Therapy by Hassan Seddik, Mouna Tamzaourte, Fadoua Rouibaa, Maha Fadlouallah, Ahmed Benkirane

“…Ophthalmologic complications with interferon therapy are rare and usually reversible. …”
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