The Impact of Farnesoid X Receptor Activation on Intestinal Permeability in Inflammatory Bowel Disease by Maja Stojancevic, Karmen Stankov, Momir Mikov

“…Activation of FXR in the intestinal tract decreases the production of proinflammatory cytokines such as interleukin (IL) 1-beta, IL-2, IL-6, tumour necrosis factor-alpha and interferon-gamma, thus contributing to a reduction in inflammation and epithelial permeability. …”
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Lymphatic Malformation, Retinoblastoma, or Facial Cleft: Atypical Presentations of PHACE Syndrome by María Fernández-Ibieta, Juan Carlos López-Gutiérrez

“…The first one was followed and treated in the pre-propranolol era and had a moderate response to corticoids and interferon.…”
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MPNs as Inflammatory Diseases: The Evidence, Consequences, and Perspectives by Hans Carl Hasselbalch, Mads Emil Bjørn

“…Early intervention with interferon-alpha2, which as monotherapy has been shown to be able to induce minimal residual disease, in combination with potent anti-inflammatory agents such as JAK-inhibitors is foreseen as the most promising new treatment modality in the years to come.…”
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Analysis of the IFN-γ-induced signal transduction pathway in fetal rejection by Irene Athanassakis

“…Although placenta lacks expression of class II MHC antigens, they can be induced either by interferon-gamma (IFN-γ) on the spongiotrophoblast zone, or by 5-azacytidine (5-azaC) on the labyrinthine trophoblast zone, two agents actively participating in a plethora of immunological and inflammatory reactions. …”
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ACSL4 promotes the formation of the proliferative subtype in hepatoblastoma by Wei Dang, Qin Li, Xiaoying Wang

“…Mechanistically, ACSL4 was found to promote cell proliferation by downregulating the interferon response signaling pathway which may implicate contribution to immunosuppression in the tumor. …”
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Oxidized Lipoproteins Suppress Nitric Oxide Synthase in Macrophages: Study of Glucocorticoid Receptor Involvement by K. E. Matthys, P. G. Jorens, B. Marescau, M. Rosseneu, H. Bult, A. G. Herman

“…However, it suppressed the iNOS activity resulting from stimulation of the cells with lipopolysaccharide with or without interferon-γ. AcLDL had no inhibitory effect, indicating that cholesterol accumulation as such was not responsible. …”
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Nephrological problems in a child with Aicardi-Goutières syndrome by Małgorzata Piejak, Zuzanna Hus, Adam Bujanowicz, Piotr Skrzypczyk, Joanna Samotyjek, Beata Jurkiewicz, Hanna Szymanik-Grzelak, Mariusz I. Furmanek, Małgorzata Pańczyk-Tomaszewska

“…Aicardi-Goutières syndrome (AGS) is a rare genetic disorder characterized by excessive interferon-alpha production, leading to central nervous system damage, manifesting as subacute encephalopathy in infancy. …”
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KSHV hijacks the antiviral kinase IKKε to initiate lytic replication. by Xiaoqian Wang, Zhenshan Liu, Xue Xu, Xin Wang, Zizhen Ming, Chengrong Liu, Hang Gao, Tingting Li, Qiming Liang

“…IKKε is a traditional antiviral kinase known for positively regulating the production of type I interferon (IFN) and the expression of IFN-stimulated genes (ISGs) during various virus infections. …”
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Prevalence and exposure variables of latent infection by mycobacterium tuberculosis in healthcare workers by Raphael Sampaio dos Santos, Katerine Moraes dos Santos, Angela Maria Mendes Abreu, Cristiane Cardoso de Paula, Regina Célia Gollner Zeitoune

“…The study also showed that interferon-gamma release assays were more commonly used as a diagnostic method compared to skin tests. …”
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Modulation of nitric oxide synthase activity in macrophages by P. G. Jorens, K. E. Matthys, H. Bult

“…., lipopolysaccharide (LPS) and interferon-γ (IFNγ). Other cytokines can modulate the induction of NO biosynthesis in macrophages. …”
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Guanylate-Binding Protein 1 Promotes Migration and Invasion of Human Periodontal Ligament Stem Cells by Shi Bai, Tao Chen, Xia Deng

“…Previous studies have shown interferon-gamma (IFN-γ) promoted migration of the V54/2 cell line and dental pulp stem cells (DPSCs), but the underlying mechanisms remain largely unknown. …”
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Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy by Patrick Hwu, Ravi Murthy, Aung Naing, Sapna P. Patel, Simon Young, Alda Tam, Nina M. Muñoz, Malea Williams, Katherine Dixon, Crystal Dupuis, Amanda McWatters, Rony Avritscher, Soraya Zorro Manrique, Kevin McHugh, David Leach, Jeffrey D. Hartgerink, Punit Prakash, Rahul A. Sheth

“…The influence of varying needle design and hydrogel-based drug delivery on the immune response to a stimulator of interferon genes (STING) agonist was evaluated using flow cytometry and single cell RNA sequencing. …”
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Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells by Hongzhuan Zhou, Huanhuan Zhang, Xia Su, Fuzhou Xu, Bing Xiao, Jin Zhang, Qi Qi, Lulu Lin, Kaidi Cui, Qinqin Li, Songping Li, Bing Yang

“…Preliminary studies have shown that knockdown of FHL2 promotes CPV replication by decreasing the expression of interferon β (IFN-β) and interferon-stimulated genes (ISGs), while overexpression of FHL2 can inhibit the replication of CPV by up-regulating the expression of IFN-β and related ISGs. …”
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Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae by Wei Yu, Peiyao Jia, Xiaobing Chu, Shengjie Li, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Yingchun Xu, Qiwen Yang

“…Furthermore, despite lower intracellular bacterial loads, ramR L58P and F165L mutants induce heightened pro‐inflammatory cytokine responses in macrophages and elevate systemic cytokine levels (interleukin [IL]2, IL4, IL6, IL12, interferon‐α, and interferon‐γ) in human blood co‐culture experiments. …”
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Efficacy and safety of 3D-therapy at HCV-related subcompensated liver cirrhosis (genotype 1b) by P. O. Bogomolov, M. V. Matsiyevich, A. O. Buyeverov, V. D. Beznosenko, Ye. V. Fedosova, M. Yu. Petrachenkova, S. V. Koblov, K. Yu. Kokina, O. S. Kuzmina, N. V. Voronkova

“…To estimate efficacy and safety of 3D mode of interferon­free therapy in patients with subcompensated liver cirrhosis (LC) of HCV etiology (genotype 1b). …”
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Synergy of rehabilitation for stress-related disorders and ARIs in school-age children under the war condition in Ukraine by I.O. Mityuryayeva-Kornijko, Ie.A. Burlaka, T.D. Klets, O.A. Panchenko, A.V. Kabantseva, E.S. Sukhodolska

“…The study was carried out as part of the program of outpatient observation of children with various acute manifestations of ARIs against the background of stress damage to the nervous system due to the war in Ukraine, and taking naturopathic drugs with immunocorrective properties (scheme (1)): 1) affinity-purified antibodies to human interferon gamma (6 mg), histamine (6 mg) and CD4 (6 mg) — a mixture of homeopathic dilutions C12, C30 and C50; or in combination with a drug with a sedative effect (scheme (1+2)): 1) affinity-purified antibodies to human gamma interferon (6 mg), histamine (6 mg) and CD4 (6 mg) — a mixture of homeopathic dilutions C12, C30 and C50; 2) affinity-purified antibodies to brain-specific protein S100 (3 mg) — a mixture of homeopathic dilutions C12, C30 and C50. …”
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Co-occurrence of Myasthenia Gravis and Multiple Sclerosis: A Case Report by G. Rynkevič, R. Kizlaitienė

“…Remission of MG was achieved with medications and thymectomy, but treatment of MS had its challenges, as first-line immunomodulating drugs interferon beta-1a and dimethyl fumarate were not effective, and second line treatment with monoclonal antibody medication rituximab and ocrelizumab showed efficacy for both diseases, MG and MS. …”
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Regulatory Role of CD4+ T Cells in Myocarditis by Daria Vdovenko, Urs Eriksson

“…So far, a direct pathogenic role has been described for both activated Th17 and Th1 effector CD4+ T cell subsets, though Th1 effector T cell-derived interferon-gamma was shown to limit myocarditis severity and prevent transition to inflammatory dilated cardiomyopathy. …”
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mosGILT antibodies interfere with Plasmodium sporogony in Anopheles gambiae by Brady Dolan, Tomás Correa Gaviria, Yuemei Dong, Peter Cresswell, George Dimopoulos, Yu-Min Chuang, Erol Fikrig

“…Following Plasmodium acquisition by Anopheles gambiae, mosquito gamma-interferon-inducible lysosomal thiol reductase (mosGILT) plays a critical role in its subsequent sporogony in the mosquito. …”
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Roles of Cells from the Arterial Vessel Wall in Atherosclerosis by Di Wang, Zhiyan Wang, Lili Zhang, Yi Wang

“…In addition, numerous types of cytokines produced by different cells from the arterial vessel wall, including endothelium-derived relaxing factors, endothelium-derived contracting factors, tumor necrosis factors, interleukin, adhesion molecules, interferon, and adventitium-derived relaxing factors, have been implicated in atherosclerosis. …”
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