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281
Chronic hepatitis B and risk of kidney involvement
Published 2013-05-01“…Moreover, renal disease may be caused by medications used for CHB treatment, e.g. direct nephrotoxicity of adefovir or tenofovir, alpha interferon-induced glomerulonephritis, etc. Relation of HBV-infection to periarteritis nodosa - necrotizing vasculitis, ischemic nephropathy is known. …”
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282
Modern modes of chronic hepatitis B treatment in daily clinical practice
Published 2014-11-01“…At application of pegilated interferon (PEG-IFN) resistance does not develop, however frequency of adverse events is high. …”
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283
Effect of decitabine on PD-L2 methylation in whole blood of iodine-induced autoimmune thyroiditis rats
Published 2025-01-01“…Following Dec intervention, the methylation level of the PD-L2 in rats increased and interferon and interleukin-23 levels decreased, albeit not significantly. …”
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284
Central Giant Cell Tumour-A Case Series
Published 2025-01-01“…Conservative treatment modalities such as interferon alpha therapy calcitonin therapy and intralesional corticosteroid injections can significantly reduce postoperative morbidity however it is important to follow up on these cases for an extended period in order to study the effects and potential recurrence of these cases. …”
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285
The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing
Published 2015-01-01“…Using Canadian list prices, the present analysis points out a paradox: while the cost per antiviral regimen is increasing, the cost per cure is decreasing, especially with interferon-free therapy. In a publicly funded health care system, the lowest cost per cure is a more valuable measure of value for public money than the cost per regimen.…”
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286
Treatment of Chronic Hepatitis C in Canadian Prison Inmates
Published 2005-01-01“…PURPOSE: To assess sustained viral response rate and adherence to standard interferon alpha-2b and ribavirin therapy in inmates with chronic hepatitis C (HCV) in Canadian penitentiaries in the Pacific region.…”
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287
Elderly Patients Are at Greater Risk of Cytopenia During Antiviral Therapy for Hepatitis C
Published 2006-01-01“…The results of antiviral therapy for hepatitis C virus (HCV) have improved recently with the use of pegylated interferon (PEG-IFN)/ribavirin (RBV) combination therapy. …”
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288
Characterization of the First Marine Pestivirus, Phocoena Pestivirus (PhoPeV)
Published 2025-01-01“…Pestiviruses generally counteract the cellular innate immune response by degradation of interferon regulatory factor 3 (IRF3) mediated by the viral N-terminal protease (N<sup>pro</sup>). …”
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289
Cytokines and Water Distribution in Anorexia Nervosa
Published 2021-01-01“…Following blood collection, 27 cytokines and chemokines were quantified using multiplex ELISA-based technology: Eotaxin, Eotaxin-3, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon- (IFN-) γ, interleukin- (IL-) 1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, interferon γ-induced protein- (IP-) 10, macrophage inflammatory protein- (MIP-) 1α, MIP-1β, monocyte chemoattractant protein- (MCP-) 1, MCP-4, thymus and activation-regulated chemokine (TARC), TNF-α, and TNF-β. …”
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290
Single-cell RNA sequencing reveals intrahepatic signature related to pathobiology of duck hepatitis A virus type 3 (DHAV-3) infection
Published 2025-02-01“…We found that infected S ducks exhibited the activation of type I and II interferon pathways with elevated expression of interferon-stimulated genes (ISGs) compared to infected R ducks and healthy controls. …”
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291
Predictors of Antiviral Therapy in a Post-Transfusion Cohort of Hepatitis C Patients
Published 2006-01-01“…The efficacy of therapy has recently improved with the addition of ribavirin and pegylated interferon. The aim of the present study was to identify the clinical, socioeconomic and health-system predictors of antiviral treatment for HCV.…”
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292
Hyperferritinemia at the patient with chronic hepatitis C
Published 2009-02-01“…., 38 years, despite of rapid virologic response at combined antiviral therapy by pegilated interferon α-2а and ribavirin, had persistently high activity of transaminases and initially high level of serum ferritin increase twice.Conclusion. …”
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293
A Rare Form of Chronic Granulomatous Disease (Type Iva) Presenting as Inflammatory Bowel Disease
Published 1996-01-01“…His gastrointestinal symptoms markedly improved during therapy with gamma-interferon. Chronic granulomatous disease can present initially with a clinical picture suggestive of chronic intestinal inflammation. …”
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294
CANDLE syndrome – a narrative review
Published 2024-09-01“…The syndrome is associated with gene mutations encoding proteasome or immunoproteasome subunits, particularly PSMB8, contributing to disrupted proteostasis and aberrant type 1 interferon production. The diagnostic criteria remain undefined, necessitating a multidisciplinary approach for accurate diagnosis and management. …”
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295
Comparative Performance of Ante-Mortem Diagnostic Assays for the Identification of <i>Mycobacterium bovis</i>-Infected Domestic Dogs (<i>Canis lupus familiaris</i>)
Published 2025-01-01“…Circulating serum cytokine concentrations of interferon gamma and TNF-α were not statistically different between the high- and low-risk groups of dogs. …”
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296
DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge
Published 2025-02-01“…DDO268 safely induces local type I interferon production and stimulates dendritic cell activation providing enhanced protection against IAV challenge. …”
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297
A cell-based model to study mechanisms of endothelial-dependent thrombin generation in response to inflammation and its modulation by hydroxychloroquine
Published 2025-01-01“…Methods: Cytokine-induced (tumor necrosis factor [TNF]-α, interleukin [IL]-1β, and interferon-γ) effects on ECs isolated from umbilical veins or human aortic tissue were assessed using calibrated automated thrombography in platelet-poor plasma. …”
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298
Viral Response to Specifically Targeted Antiviral Therapy for Hepatitis C and the Implications for Treatment Success
Published 2010-01-01“…Strategies including induction dosing with interferon and ribavirin, use of combination high-potency STAT-C molecules and an intensive emphasis on adherence to HCV antiviral therapy will be critical to the success of this promising advance in HCV therapy.…”
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299
Simultaneous measurement of multiple Th1 and Th2 serum cytokines in psoriasis and correlation with disease severity
Published 2003-01-01“…Serum levels of interleukin (IL)-6, IL-7, IL-8, and interferon (IFN)-γ have been reported elevated in psoriatic patients.…”
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300
Contribution of Genetic Factors to Sjögren’s Syndrome and Sjögren’s Syndrome Related Lymphomagenesis
Published 2015-01-01“…Moreover, genetic variations outside the MHC locus involving genes in type I interferon pathway, NF-κB signaling, B- and T-cell function and methylation processes have been shown to be associated with both SS and SS-related lymphoma development. …”
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