Advances in the Diagnosis of Latent Tuberculosis Infection by Zhang H, Guan W, Zhou J

“…Traditionally, the most commonly used clinical methods for diagnosing LTBI have been the tuberculin skin test (TST) and the interferon-gamma release assay (IGRA). Recently, however, novel skin tests, molecular biology techniques, and cytokine biomarkers have been developed. …”
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A Case of Acute Hepatitis E Infection in a Patient with Non-Hodgkin Lymphoma Treated Successfully with Ribavirin by Hasan N. Y. Haboubi, Rizwan Diyar, Ann Benton, Chin Lye Ch’ng

“…Thus awareness is important as additional treatment with ribavirin or pegylated interferon may be required, as in this case, in order to help achieve eradication.…”
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Le lymphosarcome fausse les résultats du test de la tuberculose effectué sur le sang by Cheick Coulibaly, Julia Seidl, Bettina Bernhard, Roland Plesker

“…En 2011, nous avons donc testé pour une première fois toute la colonie avec le test in vitro PRIMAGAM® (Prionics, Suisse), qui repose sur la détection de l’interféron gamma (IFN-gamma). Les résultats furent satisfaisants et sans équivoque. …”
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Current Views of Toll-Like Receptor Signaling Pathways by Masahiro Yamamoto, Kiyoshi Takeda

“…In terms of intracellular TLR-mediated signaling pathways, cytoplasmic adaptor molecules containing Toll/IL-1R (TIR) domains play important roles in inflammatory immune responses through the production of proinflammatory cytokines, nitric oxide, and type I interferon, and upregulation of costimulatory molecules. …”
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Borrelia burgdorferi Tolerance-Associated Changes in Gene Expression of Murine Macrophages by Sophia Chen, Ricki Deng, Anis Hadi, Sara Nandwana, William Ryan, John B. Presloid, R. Mark Wooten

“…Key findings revealed significant downregulation of type-I interferon signaling and associated immune responses, suggesting mechanisms of immune tolerance. …”
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Role of Acetylsalicylic Acid in Cytokine Stimulation of Macrophages in Antibody-Dependent Cellular Cytotoxicity (ADCC) by M. Jäpel, H. Lötzerich, K. Rogalla

“…Likewise ASA had little or no adverse effect on the capacity of the macrophages for stimulation by interferon-gamma (IFN-gamma) and interleukin-4 (IL-4). …”
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Sjogren’s Syndrome and TAM Receptors: A Possible Contribution to Disease Onset by Richard Witas, Ammon B. Peck, Julian L. Ambrus, Cuong Q. Nguyen

“…Like the related autoimmune disease systemic lupus erythematosus (SLE), SS patients and mouse models display accumulation of apoptotic cells and a Type I interferon (IFN) signature. Receptor tyrosine kinases (RTKs) of the Tyro3, Axl, and Mer (TAM) family are present on the surface of macrophages and dendritic cells and participate in phagocytosis of apoptotic cells (efferocytosis) and inhibition of Type I IFN signaling. …”
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Virus Infection-Induced Bronchial Asthma Exacerbation by Mutsuo Yamaya

“…Recent reports have demonstrated augmented viral production mediated by an impaired interferon response in the airway epithelial cells of asthma patients. …”
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Linfangioma circunscrito zosteriforme. Presentación de un caso by María Irene Guerrero, Carmen Graciela Santamaría Burgos, José Luis Ramírez Osorio, Giselle Fernández García

“…Como tratamiento se utilizó el interferón alfa y la cirugía en parte de las lesiones. …”
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The unexpected role of the STING protein in lipid metabolism by Vila, Isabelle K., Laguette, Nadine

“…In the past decade, the stimulator of interferon genes (STING) adaptor protein has emerged as a central platform enabling the activation of inflammatory responses in the presence of cytosolic DNAs. …”
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Severe Late-Onset Drug-Induced Immune Thrombocytopenia Following IFN β-1a Treatment: A Case Report of a 52-Year-Old Woman with Relapse-Remitting Multiple Sclerosis by Christophe Cisarovsky, Marie Théaudin, Pierre-Alexandre Bart, Grégoire Stalder, Lorenzo Alberio

“…Interferon β-1a (IFNβ1a) is considered safe in relapsing-remitting multiple sclerosis (RRMS). …”
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Cytokines and Angiogenesis in the Corpus Luteum by António M. Galvão, Graça Ferreira-Dias, Dariusz J. Skarzynski

“…Using the mare CL as a model, reports on locally produced cytokines, such as tumor necrosis factor α (TNF), interferon gamma (IFNG), or Fas ligand (FASL), pointed out their role on angiogenic activity modulation throughout the luteal phase. …”
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Targeting Toll-Like Receptors for Treatment of SLE by Christopher G. Horton, Zi-jian Pan, A. Darise Farris

“…Activation of these TLRs results in the production of inflammatory cytokines and type I interferon. Genome-wide association studies, single nucleotide polymorphism analyses as well as experimental mouse models have provided evidence of TLR signaling involvement in SLE and other autoimmune diseases. …”
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Genetic Associations in Acquired Immune-Mediated Bone Marrow Failure Syndromes: Insights in Aplastic Anemia and Chronic Idiopathic Neutropenia by Irene Mavroudi, Helen A. Papadaki

“…Various alleles and haplotypes of human leucocyte antigen (HLA) molecules have been implicated in the predisposition of developing the above diseases, as well as polymorphisms of inhibitory cytokines such as interferon-γ, tumor necrosis factor-α, and transforming growth factor-β1 along with polymorphisms on molecules of the immune system including the T-bet transcription factor and signal transducers and activators of transcription. …”
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Respuesta inmune en terneros experimentalmente infectados con diferentes dosis de Mycobacterium bovis by F.C. BLANCO, M.V. BIANCO, V. MEIKLE, S. GARBACCIO, L. VAGNONI, A. A. CATALDI, F. BIGI

“…Tambien se observo que el nivel de produccion de interferon gama (IFN-.) por celulas monociticas de sangre periferica no se asocia a la dosis de inoculo.…”
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Recent Advances in Antiviral Therapy for Chronic Hepatitis C by Akihiro Tamori, Masaru Enomoto, Norifumi Kawada

“…Due to their increased efficacy, safety, and tolerability, interferon-free oral therapies with DAAs have been approved for patients with HCV, including those with cirrhosis. …”
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Eales’ Disease: When the Rare Sounds Frequent by Beatriz Oliveira Lopes, Margarida Sena Brízido, Ana Isabel Reis, Margarida Maria Miranda, Susana Morais Pina

“…Tuberculin skin sensitive test (Mantoux screening test) and interferon-gamma release assay (IGRA) were positive in all patients. …”
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Natural Killer Cell and Large Granular Lymphocyte Deficiency in the Gut of Children with Inflammatory Bowel Disease by F Hadziselimovic, LR Emmons, U Schaub

“…The authors also present a new therapeutic strategy consisting of low dose interferon-alpha-2a that is efficacious in ameliorating ulcerative col iris and Crohn's disease and concomitantly increasing the number of natural killer cells and LGL in the gut.…”
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Cytokines that Modulate the Differentiation of Th17 Cells in Autoimmune Uveitis by Kailei Guo, Xiaomin Zhang

“…This article briefly describes the structures, mechanisms, and targeted drugs of cytokines—including interleukin (IL)-6, transforming growth factor-β1 (TGF-β1), IL-1β, IL-23, IL-27, IL-35, IL-2, IL-4, IL-21, and interferon (IFN)-γ—which have an important influence on the differentiation of Th17 cells and discusses their potential as therapeutic targets for treating autoimmune uveitis.…”
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The modern options of chronic hepatitis C antiviral therapy with daclatasvir: results of named patient program by V. T. Ivashkin, M. V. Mayevskaya, D. T. Abdurakhmanov, I. G. Bakulin, N. I. Geyvandova, M. L. Zubkin, S. N. Kizhlo, A. V. Kuznetsova, I. B. Latysheva, N. A. Mamonova, V. G. Morozov, O. I. Sagalova, Ye. V. Esaulenko, Ye. O. Lyusina

“…Before official registration of interferon-free treatment modes in 2015 experience of the application was limited to clinical trials or treatment within early approach programs. …”
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